Navigation Links
Cleveland Clinic researchers identify urgent need for Alzheimer's drug development
Date:7/2/2014

his comprehensive analysis illustrates the high rate of failure of compounds and the need for a constant supply of new drugs or a higher focus on repurposing, which can be assessed for efficacy in AD. With AD more expensive to the U.S. economy than cardiovascular disease or cancer, the Lou Ruvo Center for Brain Health research team believes the system of AD drugs must be supported, grown and coordinated to improve the success rate and development of new therapies.

In order to accelerate the drug development process and reduce the need to constantly invent new drugs, researchers note the need for more repositioning studies, which involve studying an already-approved drug in a new use or condition. For example, researchers at the Cleveland Clinic Lou Ruvo Center for Brain Health are leading a landmark Phase IIa clinical trial to determine if bexarotene (Targretin), a drug currently FDA approved to treat skin cancer, can remove a protein build-up in the brains of Alzheimer's patients, as it did in a recent animal study.


'/>"/>

Contact: Megan Pruce
prucem@ccf.org
216-445-7452
Cleveland Clinic
Source:Eurekalert

Page: 1 2

Related medicine news :

1. Cleveland Clinic selected to participate in National MDS Clinical Research Consortium
2. Cleveland Clinic researchers discover molecule that may prevent atherosclerosis
3. Cleveland Clinic Florida receives approval for transplant programs at Weston Facilities
4. Cleveland Clinic researchers investigating potential drug for treatment of Alzheimers disease
5. Cleveland Clinic study shows vitamin E may decrease cancer risk in Cowden syndrome patients
6. University Hospitals & Philips Healthcare to showcase imaging technology at Cleveland Medical Mart
7. Cleveland Clinic researcher identifies 2 new genetic mutations associated with Cowden syndrome
8. Redskins Quarterback & Lynx Shreds Athlete Kirk Cousins will Start Today vs. Cleveland Browns for Injured RG3
9. Cleveland Clinic researcher receives grant to fund autism research
10. Cleveland Clinic study shows bariatric surgery restores pancreatic function by targeting belly fat
11. Vein Expert in Winston-Salem, NC Participates in Elite Cleveland Clinic Seminar
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:11/23/2014)... November 23, 2014 Asher Milgrom, ... Aesthetics & Wellness was recently featured on ... is president and CEO of American Medical Aesthetics & ... Milgrom received a full scholarship to attend an M.D./Ph.D ... School at the University of Chicago, where his field ...
(Date:11/23/2014)... BambooFlooringChina.com , the world’s leader in bamboo flooring, ... flooring collection. Now, the business is announcing big discounts ... promotion is valid until Dec. 20, 2014. , The new ... dust-free surface, which makes it very easy to maintain. As ... wants to make its website the best shopping platform for ...
(Date:11/22/2014)... PrettyTailor , an outstanding dress ... big promotion. Customers can buy new dresses at its ... visit its website. , As a matter of fact, ... It mainly provides four types of wedding outfits, including ... girl dresses. It also provides a variety of occasion ...
(Date:11/22/2014)... (PRWEB) November 23, 2014 Today, Dylan ... its new collection of wedding dresses; the business offers ... other related accessories for ladies worldwide, allowing them to ... manager of the company, this new collection of chic ... launch. Moreover, they are offered at discounted rates now. ...
(Date:11/22/2014)... 22, 2014 Nocturia is defined ... complaint that the individual has to wake at ... report “Nocturia – Pipeline Review, H2 2014” provides ... complete with comparative analysis at various stages, therapeutics ... route of administration (RoA) and molecule type, along ...
Breaking Medicine News(10 mins):Health News:Asher Milgrom Is the Founding Doctor of AMA Skincare and Is Featured in the International Business Times 2Health News:Asher Milgrom Is the Founding Doctor of AMA Skincare and Is Featured in the International Business Times 3Health News:Asher Milgrom Is the Founding Doctor of AMA Skincare and Is Featured in the International Business Times 4Health News:Click Strand Woven Bamboo Flooring From Famous Bamboo Flooring Company BambooFlooringChina.com 2Health News:Customers Are Welcome to Shop at PrettyTailor.com 2Health News:Dylan Queen Introduces Its New Wedding Dresses 2Health News:Nocturia Therapeutic Pipeline Market Review by Drugs and Companies H2 2014 Report at RnRMarketResearch.com 2Health News:Nocturia Therapeutic Pipeline Market Review by Drugs and Companies H2 2014 Report at RnRMarketResearch.com 3Health News:Nocturia Therapeutic Pipeline Market Review by Drugs and Companies H2 2014 Report at RnRMarketResearch.com 4
... PA, 23 February 2011 - Understanding the genetics of ... specific genetic variations associated with this disorder has been ... Psychiatry implicates a brain protein called Piccolo in ... of neuronal proteins, Piccolo is a member of a ...
... increasingly popular in maternity care, but healthcare professionals need ... to a review in the March issue of the ... There is also need for greater respect and cooperation ... patients about the growing use of CAM. ...
... 2011 New research shows that medications which have ... may not have gotten approval from the Food and ... retention had been better understood. Fluid retention may explain ... medications such as Vioxx, Bextra, and Avandia. The research ...
... Feb. 23 (HealthDay News) -- People,s emotional response to challenges ... a new study. To reach that conclusion, researchers from ... a laboratory in front of a video camera and a ... the speech, and they were later asked about the emotions ...
... electronic health record system in Canada, e-health policy must ... health care reform and must take a bottom-up approach ... study published in CMAJ ( Canadian Medical ... Canada Health Infoway has invested almost $1.6 billion ...
... available in French . An electronic health ... Canada and more must be done to speed up the implementation ... be put in place effectively, doctors and front line health care ... role. These are the findings of an innovative new study assessing ...
Cached Medicine News:Health News:A new clue to the genetics of bipolar disorder: Piccolo 2Health News:Review highlights need for more education and guidance on CAM use in midwifery 2Health News:Review highlights need for more education and guidance on CAM use in midwifery 3Health News:New hypothesis explains why drugs increase risk of heart attacks and strokes 2Health News:New hypothesis explains why drugs increase risk of heart attacks and strokes 3Health News:New hypothesis explains why drugs increase risk of heart attacks and strokes 4Health News:E-health must align with health care reform 2Health News:E-health must be a priority, researchers say 2
(Date:11/21/2014)... 2014  The University of Maryland,s A. James Clark ... of the new A. James Clark Hall at the ... cultivate transformative new engineering and biomedical technologies to accelerate ... 10:00 a.m. on November 21 at the site of ... adjacent to the Jeong H. Kim Engineering Building, the ...
(Date:11/21/2014)... SAN CLEMENTE, Calif. , Nov. 21, 2014 /PRNewswire/ ... Lab Coats and Performance Scrubs carried out a new ... the medical industry,s very first "limited edition" lab ... the first female professors of surgery in the world. ... departure from its unisex predecessors, with a sleek envelope ...
(Date:11/21/2014)...  Heated dialogue in recent months about the rising ... to Gilead,s new hepatitis C drug Harvoni® – has ... what it means to put a price on patient ... while drug pricing is one of the most debated ... general business and ethical standpoint – it is also ...
Breaking Medicine Technology:University of Maryland Breaks Ground for A. James Clark Hall 2University of Maryland Breaks Ground for A. James Clark Hall 3University of Maryland Breaks Ground for A. James Clark Hall 4Medelita Introduces Medical Industry's First Limited Edition Women's Designer Lab Coat 2"The Price of Global Health" Tackles Worldwide Drug-Pricing Debate 2"The Price of Global Health" Tackles Worldwide Drug-Pricing Debate 3"The Price of Global Health" Tackles Worldwide Drug-Pricing Debate 4"The Price of Global Health" Tackles Worldwide Drug-Pricing Debate 5
... Calif., March 10, 2011 OXIS International, Inc., (OTC ... announced that it will hold a conference call with ... Eastern (8:00 a.m. Pacific). During the call ... will review significant business developments, discuss the Company,s growth ...
... 2011 STAAR Surgical Company (Nasdaq: STAA ... invasive ophthalmic products, today announced that it has entered ... the exclusive distribution of STAAR intraocular lenses in Australia. ... publicly traded in Australia, will market STAAR,s Visian ICL ...
Cached Medicine Technology:STAAR Surgical Enters Into Distribution Agreement With Ellex in Australia 2STAAR Surgical Enters Into Distribution Agreement With Ellex in Australia 3
... the First and Only ... powerful technology of RESTORE with the ... create the unrivaled RESTOREPRIME. The ultimate ... coverage for managing patients with bilateral ...
NIVEA body Good-bye Cellulite Gel-Cream visibly reduces the appearance of cellulite....
... PRIMEADVANCED is a nonrechargeable neurostimulator designed for ... needs or do not want the maintenance ... of their pain. What makes RESTOREADVANCED ... neurostimulators is the ease and efficiency with ...
All-natural porcine collagen can be used in open or laparoscopic placement....
Medicine Products: