Navigation Links
Childless women with fertility problems at higher risk of hospitalization for psychiatric disorders

Istanbul, 2 July 2012: While many small studies have shown a relationship between infertility and psychological distress, reporting a high prevalence of anxiety, mood disorders and depressive symptoms, few have studied the psychological effect of childlessness on a large population basis. Now, based on the largest cohort of women with fertility problems compiled to date, Danish investigators have shown that women who remained childless after their first investigation for infertility had more hospitalisations for psychiatric disorders than women who had at least one child following their investigation.

The results of the study were presented today at the annual meeting of ESHRE (European Society of Human Reproduction and Embryology) by Dr Birgitte Baldur-Felskov, an epidemiologist from the Danish Cancer Research Center in Copenhagen.

Most studies of this kind have been based on single clinics and self-reported psychological effects. This study, however, was a nationwide follow-up of 98,737 Danish women investigated for infertility between 1973 and 2008, who were then cross-linked via Denmark's population-based registries to the Danish Psychiatric Central Registry. This provided information on hospitalisations for psychiatric disorders, which were divided into an inclusive group of "all mental disorders", and six discharge sub-groups which comprised "alcohol and intoxicant abuse", "schizophrenia and psychoses", "affective disorders including depression", "anxiety, adjustment and obsessive compulsive disorder", "eating disorders", and "other mental disorders".

All women were followed from the date of their initial fertility investigation until the date of psychiatric event, date of emigration, date of death, date of hospitalisation or 31st December 2008, whichever came first. Such studies, said Dr Baldur-Felskov, could only be possible in somewhere like Denmark, where each citizen has a personal identification number which can be linked to any or all of the country's diagnostic registries.

Results of the study showed that, over an average follow-up time of 12.6 years (representing 1,248,243 woman-years), 54% of the 98,737 women in the cohort did have a baby. Almost 5000 women from the entire cohort were hospitalised for a psychiatric disorder, the most common discharge diagnosis being "anxiety, adjustment and obsessive compulsive disorders" followed by "affective disorders including depression".

However, those women who remained childless after their initial fertility investigation had a statistically significant (18%) higher risk of hospitalisations for all mental disorders than the women who went on to have a baby; the risk was also significantly greater for alcohol/substance abuse (by 103%), schizophrenia (by 47%) and other mental disorders (by 43%). The study also showed that childlessness increased the risk of eating disorders by 47%, although this was not statistically significant.

However, the most commonly seen discharge diagnosis in the entire cohort (anxiety, adjustment and obsessive compulsive disorders) was not affected by fertility status.

Commenting on the study's results, Dr Baldur-Felskov said: "Our study showed that women who remained childless after fertility evaluation had an 18% higher risk of all mental disorders than the women who did have at least one baby. These higher risks were evident in alcohol and substance abuse, schizophrenia and eating disorders, although appeared lower in affective disorders including depression.

"The results suggest that failure to succeed after presenting for fertility investigation may be an important risk modifier for psychiatric disorders. This adds an important component to the counselling of women being investigated and treated for infertility. Specialists and other healthcare personnel working with infertile patients should also be sensitive to the potential for psychiatric disorders among this patient group."


Contact: Christine Bauquis
European Society of Human Reproduction and Embryology

Related medicine news :

1. Taller, Heavier Women May Face Higher Ovarian Cancer Risk
2. 62 percent of men and 37 percent of women over the age of 65 are sexually active
3. Obese White Women Shying Away From Colon Cancer Screening
4. Study: Women not getting enough exercise; at risk of developing metabolic syndrome
5. Timing pregnancy an important health concern for women
6. White Women Make Up Bulk of Assisted-Living Residents
7. Stress contributes to cognitive declines in women with breast cancer, researcher says
8. Women Less Apt Than Men to Get Recommended Daily Exercise
9. Overweight Pregnant Women at Higher Risk for Complications
10. Women With Older Partners More Often Admitted to Nursing Homes
11. Research shows efficacy of treatment model developed at Women & Infants
Post Your Comments:
(Date:11/24/2015)... ... 2015 , ... Preparing for the LDT Regulation:, CLIA Won’t Satisfy the FDA, ... , FDA has long asserted that design and manufacture of Laboratory Developed Tests (LDTs) ... not meet the device regulations. , Come up short in an inspection and the ...
(Date:11/24/2015)... Richey, FL (PRWEB) , ... November 24, 2015 , ... ... deems a growing epidemic as deaths from prescription opioids in the United States grew ... and cocaine. In 2013 alone, opioids were involved in 37 percent of all fatal ...
(Date:11/24/2015)... ... November 24, 2015 , ... American Family Care (AFC), the ... of a holiday pop-up clinic located in Metro Atlanta’s North Point Mall. The clinic ... and different way. The location is scheduled to operate through Dec. 24. , Holiday ...
(Date:11/24/2015)... CA (PRWEB) , ... November 24, 2015 , ... Cold Shoulder , LLC launched ... Kickstarter last week and hit their goal of $20,000 in under 10 hours. ... aims to bring the new PRO Weight Loss Vest to the market. , The PRO ...
(Date:11/24/2015)... ... November 24, 2015 , ... ... its exceptional customer service: the TrustDale certification. The award recognizes good companies for ... stone honing , tile and grout, and hard surface restoration company earned this ...
Breaking Medicine News(10 mins):
(Date:11/24/2015)... , November 24, 2015 F1000Workspace ... scientists - since it was launched just six months ago. ... management and authoring platform for scientists - since it was ... references have been loaded on to F1000Workspace - ... - since it was launched just six months ago. ...
(Date:11/24/2015)... , Nov. 24, 2015 iRhythm Technologies, Inc. , ... care, today announced that it will participate in the 27th Annual ... New York, NY . Kevin King ... Tuesday December 1, 2015 at 8:50am ET. ... . --> . --> ...
(Date:11/24/2015)... The uptake of recently approved and pipeline premium products for Type 1 ... 2021, says GBI Research . --> ... Diabetes Mellitus (T1DM), will be a key driver of market growth to ... The uptake of recently approved and pipeline premium products for Type ... to 2021, says GBI Research . ...
Breaking Medicine Technology: