Navigation Links
Certain bacteria suppress production of toxic shock toxin: Probiotic potential looms
Date:3/22/2013

Certain Streptococci increase their production of toxic shock syndrome toxin 1, sometimes to potentially dangerous levels, when aerobic bacteria are present in the vagina. But scientists from the University of Western Ontario have discovered certain strains of lactobacillus bacteria are capable of dampening production of that toxin according to research published in the journal Applied and Environmental Microbiology.

"The risk of potentially fatal toxic shock syndrome appears to be influenced by the types of bacteria present in the vagina," says principal investigator Gregor Reid.

In planning the study, "I figured that the Staphylococcus aureus strains with the ability to produce toxic shock syndrome toxin might only do this under certain environmental conditions," says Reid. "In the vagina, that means depending on pH and the other bacteria living there."

The researchers took swabs from women with clinically healthy vaginal status, with intermediate status, and from those diagnosed with bacterial vaginosis. They then identified the bacterial species, and assayed for toxic shock syndrome toxin 1. "In particular, Streptococcus agalactiae, often referred to as Group B streptococci, an organism of particular concern when giving birth, increased toxin production 3.7-fold," says Reid. But various species of lactobacillus repressed toxin production, one by 72 percent.

"These experiments emphasize that for proper clinical care of women, we need to know all bacterial types present in the vagina," says Reid. "Culturing is inadequate, and while some microscopy is feasible if the viewer develops the expertise to assess the vaginal smears, rapid 16s sequencing systems are needed as a diagnostic tool," because many species are "very difficult to culture," or have never been cultured.

"We need to vastly improve how we diagnose infections and determine the risk of infection of women," says Reid. He also recommends "improving our ability to manipulate microbiota [with probiotics] in lieu of using broad spectrum antibiotics that were developed 40 years ago, and are not very effective in the vagina, and certainly not designed to neutralize toxins."


'/>"/>

Contact: Jim Sliwa
jsliwa@asmusa.org
202-942-9297
American Society for Microbiology
Source:Eurekalert

Related medicine news :

1. With Certain Strokes, Effects Can Persist a Decade Later
2. Video game exercise for an hour a day may enhance certain cognitive skills
3. Certain Men May Face Higher Risk of Brain Injury
4. Certain Diabetes Medications May Lower Heart Failure Risk
5. Certain Sleep Aids May Raise Hip Fracture Risk in Nursing Homes: Study
6. Obesity, physical inactivity linked with risk for certain molecular subtype of colorectal cancer
7. Codeine Risky for Kids After Certain Surgeries, FDA Says
8. The science of uncertainty in genomic medicine
9. USC research finds certain contraceptive may pose risk of Type 2 diabetes for obese women
10. Certain Skin Cancers More Common in HIV-Positive People
11. Certain Jobs May Still Pose Risk for Asthma
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:5/21/2017)... ... May 20, 2017 , ... Pot. Reefer. Grass. Mary Jane. No matter what ... its attributes like never before. More than a map, new social marketplace Weedable ... strains, products – and for the first time – each other. A social marketplace ...
(Date:5/21/2017)... Pittsburgh, PA (PRWEB) , ... May 21, 2017 , ... ... in 2012, New York became the first state to require that hospitals follow a ... widespread controversy in the medical community as to whether such steps would have saved ...
(Date:5/19/2017)... ... May 19, 2017 , ... DMG Productions ... episode of Innovations with Ed Begley, Jr., airing fourth quarter 2017 on FOX ... a clean, organic dietary supplement made from naturally occurring ingredients. Innovations will enlighten ...
(Date:5/19/2017)... FL (PRWEB) , ... May 19, 2017 , ... ... asset protection services and retirement planning assistance to families and business owners in ... Sclerosis Society to advocate for MS sufferers and their families. , Multiple sclerosis ...
(Date:5/19/2017)... ... 18, 2017 , ... ML Billing, 2016 Billing Company of the Year ... in large group practices, is pleased to announce their 30th anniversary. Not only has ... standard in all aspects of full-service medical billing. This has allowed ML Billing to ...
Breaking Medicine News(10 mins):
(Date:5/6/2017)... , May 5, 2017  Hill-Rom Holdings, Inc. (NYSE: ... approximately 100,000 square feet to its Welch Allyn campus. ... its commitment to bring more than 100 new jobs ... Welch Allyn has maintained a significant presence for more ... these new positions, a large portion of which will ...
(Date:5/4/2017)... May 4, 2017  DarioHealth Corp. (NASDAQ: DRIO), a ... big data solutions, today announced that it is teaming ... STI Technologies Limited to lower diabetes healthcare costs in ... innoviCares card, which is available throughout all provinces and ... will be eligible for additional savings when shopping for ...
(Date:5/3/2017)... May 3, 2017  Getinge, a leading global ... quality enhancement and cost efficiency within healthcare and ... of contemporary practice demonstrating that intra-aortic balloon counterpulsation ... critically ill patients. The single-center, retrospective, observational study ... volume MEGA ® 50cc intra-aortic balloon (IAB) ...
Breaking Medicine Technology: