Navigation Links
Cause and potential treatment found for cancer drug's kidney toxicity
Date:6/2/2011

if you remove it, there don't appear to be major negative consequences," Pabla said. The findings point toward using protein kinase C inhibitors as an adjunct therapy for patients experiencing kidney problems and potentially for all cancer patients treated with cisplatin if the enhanced efficacy finding continues to hold up, Dong said.

The scientists note that reducing the cisplatin dose decreases kidney toxicity but also decreases its efficacy and may leave the patient resistant to even higher doses of the drug. In the more than 30-year history with cisplatin, related drugs, such as carboplatin, have been developed to circumvent kidney damage, but those drugs tend to have more limited use, be less effective and/or have additional side effects. In more recent years, the focus has been on trying to protect the kidneys.

Next steps include working with chemists to see if an even more effective inhibitor can be developed.


'/>"/>

Contact: Toni Baker
tbaker@georgiahealth.edu
706-721-4421
Georgia Health Sciences University
Source:Eurekalert  

Page: 1 2

Related medicine news :

1. GW researchers show host Mta1 gene is required for optimal survival of schistosome parasites, a leading global cause of cancer
2. Cosmetics can cause serious adverse effects
3. Heart scientists discover protein that may be 1 cause of heart failure
4. Dietary inorganic nitrate may reduce heart dysfunction caused by powerful anti-cancer drug
5. Newer Epilepsy Meds Less Likely to Cause Birth Defects: Study
6. A gene that fights cancer, but causes it too
7. Chiropractic Spinal Manipulation Wont Cause Chest Injuries, Study Contends
8. Mayo Clinic finds new genetic cause of neurodegeneration
9. Morning Heart Attacks Cause More Damage, Study Finds
10. Increased computer use by adolescents cause for concern
11. Wrestlers Quick Weight Loss May Cause Mental Confusion
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Cause and potential treatment found for cancer drug's kidney toxicity
(Date:12/22/2014)... Fad diets have been around forever ... most fad diets have hung around so long is that ... is that, as the body becomes accustomed to new eating ... to reset the metabolism to return the body to fast ... all-inclusive diet plans that are medically supervised throughout. ...
(Date:12/22/2014)... 22, 2014 The holidays are here, and ... season. Many may be thinking about how to enjoy these ... few weeks. Health Republic Insurance of New York has compiled ... Chernus, to provide some smart ideas to enjoy the holiday ... 1)    Avoid arriving at a holiday gathering over-hungry , Have a ...
(Date:12/22/2014)... York, NY (PRWEB) December 22, 2014 ... 2014 stronger than ever, having invested more than ... injured service members, veterans and their families. , ... for nearly a dozen nonprofits, helping with: veteran ... nursing scholarships; and life-coaches for severely injured veterans. ...
(Date:12/22/2014)... (PRWEB) December 22, 2014 In recognition ... November sales to Hero Reward, a local organization that ... charge. , Located on a couple hundred ... Reward Program offers lodging, world class fishing, hunting, hiking, ... program was founded several years ago to support U.S. ...
(Date:12/22/2014)... December 22, 2014 TheHardwareCity.com now stocks ... with many useful features. Customers of the large online ... the new gloves delivered to their home or workplace ... hand tools that incorporate heavy duty magnets, which make ... allows workers to store metal parts on the back ...
Breaking Medicine News(10 mins):Health News:Diet Doc Announces the Difference Between Fad Diets and Real Weight Loss Programs to Help Dieters Make the Best Choice 2Health News:Diet Doc Announces the Difference Between Fad Diets and Real Weight Loss Programs to Help Dieters Make the Best Choice 3Health News:Diet Doc Announces the Difference Between Fad Diets and Real Weight Loss Programs to Help Dieters Make the Best Choice 4Health News:Health Republic Insurance of New York Offers Five Simple Tips to Eat Healthy During the Holidays 2Health News:Bob Woodruff Foundation Poised to Reach More Vets Thanks to Banner Year 2Health News:Bob Woodruff Foundation Poised to Reach More Vets Thanks to Banner Year 3Health News:Bob Woodruff Foundation Poised to Reach More Vets Thanks to Banner Year 4Health News:Bob Woodruff Foundation Poised to Reach More Vets Thanks to Banner Year 5Health News:Bob Woodruff Foundation Poised to Reach More Vets Thanks to Banner Year 6Health News:Bob Woodruff Foundation Poised to Reach More Vets Thanks to Banner Year 7Health News:Discount Labels Donates Portion of November Sales to Hero Reward Program 2Health News:MagnoGrip Pro Utility Magnetic Gloves on Sale at TheHardwareCity.com 2
... 15 , Event: Medtronic Celebration of Courage Gala, Date: Saturday, ... Cocktail Hour begins at 6 p.m. ... Silent and live auction throughout the evening, ... Avenue South Minneapolis, Minnesota, ...
... Ill., July 15 Capping a season of,substantial ... Medical Association (AVMA) will present Congressman Chip,Pickering (R-Miss.) ... 145th,annual convention in New Orleans on Sunday, July ... DVM, will give Rep. Pickering,the award during the ...
... Life Recovery Systems HD, LLC,developer of innovative medical devices ... larger space in the Hopper Technology Center, 150,Hopper Avenue, ... "As demand for the ThermoSuit(R) System increases, we ... infrastructure we will have more,space for inventory and will ...
... will help Nevada Cancer Institute Funnel Cancer Research to ... ... Physicians and patients of,community-based medical practices in Nevada and SW ... Practice,Management Journal and Nevada Cancer Institute (NVCI). The new partnership,will provide ...
... the study of genetic variation that influences an individual,s ... in all of medical research, including psychiatry. It ... of consistent and replicable findings across multiple studies, but ... new study scheduled for publication in the June 15th ...
... Orleans, LA A ground-breaking study by researchers at the ... published in the August 2008 issue of Resuscitation ... Americans -- sudden cardiac arrest. The researchers stopped the heart ... from cardiac arrest, waited 25 minutes, and then resuscitated them ...
Cached Medicine News:Health News:Rep. Pickering to Receive First-Ever AVMA Advocacy Award 2Health News:Physicians Practice and Nevada Cancer Institute Partner to Improve Patient Care 2Health News:Physicians Practice and Nevada Cancer Institute Partner to Improve Patient Care 3Health News:New study replicates association between genetic variation and antidepressant treatment response 2Health News:LSUHSC study finds high-dose HBO2 therapy extends survival window after cardiopulmonary arrest 2
(Date:12/22/2014)... 2014  ConvaTec, a privately-held medical products and technologies ... Interim Chief Executive Officer of the company, effective December ... Berger .  "The Board of Directors of ConvaTec thanks ... the past three years," said Magnus Lundberg , ... confident that the company is well positioned for the ...
(Date:12/22/2014)... STOCKHOLM , Dec. 22, 2014 /PRNewswire/ ... Auxilium Pharmaceuticals, Inc. today announced that the Committee for ... Medicines Agency (EMA) has adopted a positive opinion for ... treatment of adult men with Peyronie,s disease with a ... degrees at the start of therapy. The ...
(Date:12/22/2014)... 2014  Mark Farrah Associates (MFA), www.markfarrah.com ... of the 2015 marketplace exchange projections and insights ... According to a recent ASPE (Office of ... of Health and Human Services) report, an estimated ... plans through the Marketplace as of October 2014 ...
Breaking Medicine Technology:ConvaTec Names Paul Moraviec Interim CEO Effective December 22, 2014 2Sobi's Xiapex receives positive opinion by CHMP for the treatment of Peyronie's disease 2Sobi's Xiapex receives positive opinion by CHMP for the treatment of Peyronie's disease 3Sobi's Xiapex receives positive opinion by CHMP for the treatment of Peyronie's disease 4Sobi's Xiapex receives positive opinion by CHMP for the treatment of Peyronie's disease 5Sobi's Xiapex receives positive opinion by CHMP for the treatment of Peyronie's disease 6Insights into the Marketplace and Individual Market Growth 2
... progression reduced by 40 percent compared,to delayed treatment ... Pharma AG,Germany, announced today new data, which show ... with a first event suggestive of multiple sclerosis ... as measured by the Expanded Disability Status Scale,(EDSS) ...
... in Primate Study, CHICAGO, May 02, 2007 /PRNewswire-FirstCall/ ... its novel respiratory,antibiotic, Cethromycin, was shown to be ... reached from a,primate study where a 30-day course ... dose of inhaled anthrax as compared to,the standard ...
Cached Medicine Technology:Immediate Treatment of Early MS Patients with Betaferon,Significantly Delayed Permanent Disability 2Immediate Treatment of Early MS Patients with Betaferon,Significantly Delayed Permanent Disability 3Immediate Treatment of Early MS Patients with Betaferon,Significantly Delayed Permanent Disability 4Cethromycin Shown Effective Against Anthrax in Study 2Cethromycin Shown Effective Against Anthrax in Study 3Cethromycin Shown Effective Against Anthrax in Study 4
... Laboratories is a national reference laboratory and ... and development. ARUP offers an extensive test ... tests in clinical and anatomic pathology. Owned ... clients include more than half of the ...
... ARUP Laboratories is a national reference laboratory ... research and development. ARUP offers an extensive ... medical tests in clinical and anatomic pathology. ... Laboratories' clients include more than half of ...
... Laboratories is a national reference laboratory and ... and development. ARUP offers an extensive test ... tests in clinical and anatomic pathology. Owned ... clients include more than half of the ...
... is a national reference laboratory and a ... development. ARUP offers an extensive test menu ... in clinical and anatomic pathology. Owned by ... include more than half of the nation's ...
Medicine Products: