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Cancer scientists discover genetic diversity in leukemic propagating cells
Date:1/19/2011

findings published in 2007 when the Dick team developed a method to convert normal human blood cells into "human" leukemia stem cells. The converted cells, when transplanted into special mice that permit the growth of human cells, can replicate the entire disease process from the very moment it begins.

In 1994, Dr. Dick identified the first cancer stem cell in leukemia, following on the original discovery in 1961 of the blood stem cell by renowned OCI scientists, Drs. Ernest McCulloch and James Till -- a discovery that formed the basis of all current stem cell research. Dr. Dick, who holds the Canada Research Chair in Stem Cell Biology, has published other findings showing that colon cancer arises from stem cells specific to the tumour.


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Contact: Jane Finlayson
jane.finlayson@uhn.on.ca
416-946-2846
University Health Network
Source:Eurekalert

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