Navigation Links
Cancer Drug Doesn't Speed Up Tumor Growth, Researchers Say

THURSDAY, Feb. 7 (HealthDay News) -- The anticancer drug Sutent (sunitinib) does not cause tumors to grow faster after treatment ends, according to a new study.

Previous research in animals suggested that tumor growth may accelerate after patients stopped taking Sutent. The new findings, from a study of kidney cancer patients, indicate that the drug does not pose lingering risks for humans.

The researchers analyzed data from a phase 3 clinical trial that led to Sutent's approval. They concluded that regardless of how long patients took the drug, it did not cause harm, did not speed up tumor growth and survival was not shortened after treatment ended, according to the findings published online Feb. 7 in the journal Cell Reports.

During treatment, Sutent slowed tumor growth and extended patients' lives, the investigators pointed out in a journal news release.

Sutent, which is approved for the treatment of several different cancers, targets proteins on the blood vessels that feed tumors.

"Last year, I was approached by two patients who had grave concerns about taking sunitinib due to an article [about research] conducted in animals. I realized that if clinical data exist that refute basic science, they must be published," study senior author Dr. Tito Fojo, of the U.S. National Cancer Institute, said in the news release.

These new findings should reassure patients, the study authors suggested.

"We hope [these findings] can be generalized to similar drugs but recognize that further studies will be needed," study first author Dr. Krastan Blagoev, of the U.S. National Science Foundation, said in the news release. "Nevertheless, other drugs also approved worldwide for a variety of cancers -- including sorafenib, pazopanib, and axitinib -- are similar to sunitinib, and this will give some reassurances that one need not expect things to get worse after such drugs are discontinued."

More information

The U.S. National Library of Medicine has more about sunitinib (Sutent).

-- Robert Preidt

SOURCE: Cell Reports, news release, Feb. 7, 2013

Copyright©2012 ScoutNews,LLC.
All rights reserved  

Related medicine news :

1. Study Suggests Vaccine May Help Kids With Brain Cancer
2. New Stool Test Might Aid in Early Detection of Colon Cancer
3. Study reveals how cancer drug causes diabetic-like state
4. How a cancer drug leads to diabetes
5. You Survived Cancer: Now Pay Attention to Your Overall Health
6. New drug prevents spread of human prostate cancer cells
7. Eliminating the good cholesterol receptor may fight breast cancer
8. Taller, Heavier Women May Face Higher Ovarian Cancer Risk
9. Experimental Chemo Combo for Colon Cancer Disappoints
10. Veggies Like Broccoli, Cabbage May Help Fight Breast Cancer: Study
11. Targeted therapeutics for colon cancer to be presented at AACR meeting
Post Your Comments:
Related Image:
Cancer Drug Doesn't Speed Up Tumor Growth, Researchers Say
(Date:6/26/2016)... Orion, Clarkston, Michigan (PRWEB) , ... June 26, ... ... with respect to fertility once they have been diagnosed with endometriosis. These women ... intercourse but they also require a comprehensive approach that can help for preservation ...
(Date:6/25/2016)... (PRWEB) , ... June 25, 2016 , ... The temporary closing of Bruton Memorial Library ... City Observer , brings up a new, often overlooked aspect of head lice: the parasite’s ... for fumigation is not a common occurrence, but a necessary one in the event that ...
(Date:6/25/2016)... Beach, CA (PRWEB) , ... June 25, 2016 , ... ... UCLA with Magna Cum Laude and his M.D from the David Geffen School of ... Diego and returned to Los Angeles to complete his fellowship in hematology/oncology at the ...
(Date:6/25/2016)... ... ... Conventional wisdom preaches the benefits of moderation, whether it’s a matter of indulgence ... high can result in disappointment, perhaps even self-loathing. However, those who set the bar ... from reveals that behind the tendency to set low expectations is ...
(Date:6/24/2016)... ... June 24, 2016 , ... June 19, 2016 is ... associated with chronic pain and the benefits of holistic treatments, Serenity Recovery Center ... suffering with Sickle Cell Disease. , Sickle Cell Disease (SCD) is a disorder of ...
Breaking Medicine News(10 mins):
(Date:6/23/2016)... INDIANAPOLIS , June 23, 2016 If ... Leaders Scholarship is any indication, the future is in ... at by the Diabetes Scholars Foundation ... the way of academic and community service excellence. ... since 2012, and continues to advocate for people with ...
(Date:6/23/2016)... 23, 2016  Guerbet announced today that it has ... Horizon Award . One of 12 suppliers ... for its support of Premier members through exceptional local ... and commitment to lower costs. ... of our outstanding customer service from Premier," says ...
(Date:6/23/2016)... June 23, 2016  Experian Health, the ... transforming the patient payment and care experience, ... new products and services that will enhance ... cycle offerings. These award-winning solutions will enable ... remain compliant in an ever-changing environment and ...
Breaking Medicine Technology: