Navigation Links
Brain-imaging study links cannabinoid receptors to post-traumatic stress disorder
Date:5/14/2013

ow very well that people with PTSD who use marijuanaa potent cannabinoidoften experience more relief from their symptoms than they do from antidepressants and other psychiatric medications. Clearly, there's a very urgent need to develop novel evidence-based treatments for PTSD."

The study divided 60 participants into three groups: participants with PTSD; participants with a history of trauma but no PTSD; and participants with no history of trauma or PTSD. Participants in all three groups received a harmless radioactive tracer that illuminates CB1 receptors when exposed to positron emissions tomography (PET scans). Results showed that participants with PTSD, especially women, had more CB1 receptors in brain regions associated with fear and anxiety than volunteers without PTSD. The PTSD group also had lower levels of the neurotransmitter anandamide, an endocannabinoid that binds to CB1. If anandamide levels are too low, Dr. Neumeister explains, the brain compensates by increasing the number of CB1 receptors. "This helps the brain utilize the remaining endocannabinoids," he says.

Much is still unknown about the effects of anandamide in humans but in rats the chemical has been shown to impair memory. "What is PTSD? It's an illness where people cannot forget what they have experienced," Dr. Neumeister says. "Our findings offer a possible biological explanation for this phenomenon."

Current diagnostics for PTSD rely on subjective measures and patient recall, making it difficult to accurately diagnose the condition or discern its symptoms from those of depression and anxiety. Biological markers of PTSD, such as tests for CB1 receptors and anandamide levels, could dramatically improve diagnosis and treatment for trauma victims.

Among the 1.7 million men and women who have served in the wars in Iraq and Afghanistan, an estimated 20% have PTSD. But PTSD is not limited to soldiers. Trauma from sexual abuse, domestic violence, car accident
'/>"/>

Contact: Lorinda Klein
lorindaann.klein@nyumc.org
212-404-3533
NYU Langone Medical Center / New York University School of Medicine
Source:Eurekalert

Page: 1 2 3

Related medicine news :

1. Study Suggests Vaccine May Help Kids With Brain Cancer
2. Study reveals how cancer drug causes diabetic-like state
3. Coffee Drinking in Pregnancy Wont Lead to Sleepless Baby: Study
4. Lower GI problems plague many with rheumatoid arthritis, Mayo Clinic study finds
5. Veggies Like Broccoli, Cabbage May Help Fight Breast Cancer: Study
6. No Added Cancer Risk From Hip Replacement Materials: Study
7. Reported Decline in U.S. Pneumonia Deaths May Be False: Study
8. Early Study Finds Some Promise for Lung Cancer Vaccine
9. Narcissists Often Ace Job Interviews, Study Finds
10. Sexual objectification of female artists in music videos exists regardless of race, MU study finds
11. Soy may alleviate hot flashes in menopause, large-scale study finds
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:4/23/2014)... and accessible detection methods that can rapidly screen ... a single cell inside that population has been ... Lu. , In the Royal Society of Chemistry ... that he and his coworkers have developed a ... a protein ( Chem. Sci. , 2014, DOI: ...
(Date:4/23/2014)... and vegetables are often displayed in the popular ... also plenty of high-sugar foods. A new study ... is portrayed in children,s TV programmes as well ... dietary habits and weight status. , Steingerdur Olafsdottir,s ... in the popular Swedish children,s TV show Bolibompa. ...
(Date:4/23/2014)... scientists led by a researcher from the Cancer Science ... of Singapore has identified the cancer specific stem cell ... possibility of developing new drugs for the treatment of ... research group, led by Dr Chan Shing Leng, Research ... time that a cancer-specific variant of a cell surface ...
(Date:4/23/2014)... research, published in the journal Oncotarget , ... different appearances or their own DNA signatures within ... difficult to design effective, targeted treatment strategies. , ... EGFR mutation and either the KRAS or BRAF ... by the EGFR gene mutation have that specific ...
(Date:4/23/2014)... of Alzheimer,s disease has been a rapidly evolving ... the latest crook in the research road, scientists ... between proteins associated with the disease. The report, ... Neuroscience , could have important implications for developing ... and colleagues explain that for years, research has ...
Breaking Medicine News(10 mins):Health News:Following a protein's travel inside cells is key to improving patient monitoring, drug development 2Health News:High-calorie and low-nutrient foods in kids' TV 2Health News:Scientists identify cancer specific cell for potential treatment of gastric cancer 2Health News:Scientists identify cancer specific cell for potential treatment of gastric cancer 3Health News:Non-uniform genetic mutations identified in lung cancers could lead to targeted treatment 2
... 8 ChildCare Education Institute (CCEI), a distance training institution ... give professional development training hours to ... child care providers can log in to CCEI,s learning management ... 2009 and May 15th, 2009 and receive five (5) hours ...
... Income Rises 172% to Record $2.3 MillionCHICAGO, May 8 Second quarter highlights: , ... Increase to $2.3 Million , Gross Profit Margin ... 46% Gross Profit Increase , ... , Year-to-date highlights: , , , ...
... Valeant Pharmaceuticals International (NYSE: VRX ) ... held company located in Poland for approximately $28 million. ... Poland into multiple therapeutic categories. EMO-FARM has a strong ... portfolio of currently marketed products and additional products under ...
... Ohio, May 8 James "Buster" Douglas, former ... President Obama in his brand new inspirational diabetic ... said, in "Buster,s Backyard Bar-B-Q Knockout Diabetes Diet," ... Kindle versions in time to order for Mother,s ...
... During May,s "National Brain Tumor Awareness Month"WASHINGTON, May 8 ... the sad news of his brother,s death from a brain ... of loss -- over 200,000 people will be diagnosed with ... an effort to bring awareness and ultimately find a cure, ...
... have less cardiovascular disease than those who smoke, ... men and women in Norway. Smoking, say the ... mortality from various causes. , The results, presented ... other studies have indicated, but, says investigator Professor ...
Cached Medicine News:Health News:ChildCare Education Institute Gives Child Care Staff Access to Professional Development Courses in Honor of Provider Appreciation Day, May 8th 2Health News:The Female Health Company Reports 67% Increase in Second Quarter Earnings 2Health News:The Female Health Company Reports 67% Increase in Second Quarter Earnings 3Health News:The Female Health Company Reports 67% Increase in Second Quarter Earnings 4Health News:The Female Health Company Reports 67% Increase in Second Quarter Earnings 5Health News:The Female Health Company Reports 67% Increase in Second Quarter Earnings 6Health News:The Female Health Company Reports 67% Increase in Second Quarter Earnings 7Health News:The Female Health Company Reports 67% Increase in Second Quarter Earnings 8Health News:The Female Health Company Reports 67% Increase in Second Quarter Earnings 9Health News:Valeant to Acquire Polish Dermatology Company 2Health News:President Obama's New Knockout Mother's Day Message from Champ 2Health News:Grey Ribbon Crusade(TM) Promotes National Unification in the Fight Against Brain Tumors 2Health News:30-year follow-up study: 'Tremendous' impact of smoking on mortality and cardiovascular disease 2
(Date:1/15/2014)... Jan. 15, 2014  Humberto C. Antunes,  Galderma  worldwide CEO, ... the Journal of Drugs in Dermatology (JDD) ... (ODAC). The event is January 17-20, 2014, at the Omni Orlando ... The ODAC is a distinguished event ...
(Date:1/15/2014)... 2014  In an unprecedented effort to curb the spread of "superbugs" ... transport vehicles, an advanced and portable UV germicidal lamp manufactured by ... time. In order to prevent EMS paramedics and ... West Palm Beach Fire Rescue is the first ...
(Date:1/15/2014)... Jan. 15, 2014  Echo Therapeutics, Inc. (Nasdaq: ... Symphony® CGM System as a non-invasive, wireless continuous glucose ... , Executive Chairman and Interim CEO of Echo Therapeutics, ... Annual Equity Conference. Mr. Doman will ...
Breaking Medicine Technology:Galderma's global leader honored with a "Lifetime in Dermatology Achievement Award" by Journal of Drugs in Dermatology 2Galderma's global leader honored with a "Lifetime in Dermatology Achievement Award" by Journal of Drugs in Dermatology 3Galderma's global leader honored with a "Lifetime in Dermatology Achievement Award" by Journal of Drugs in Dermatology 4Superbugs No Longer Ride In Rescue Vehicles 2Echo Therapeutics to Present at the Noble Financial Capital Markets' Tenth Annual Equity Conference 2Echo Therapeutics to Present at the Noble Financial Capital Markets' Tenth Annual Equity Conference 3
... ARUP Laboratories is a national reference laboratory ... research and development. ARUP offers an extensive ... medical tests in clinical and anatomic pathology. ... Laboratories' clients include more than half of ...
... ARUP Laboratories is a national reference laboratory ... research and development. ARUP offers an extensive ... medical tests in clinical and anatomic pathology. ... Laboratories' clients include more than half of ...
... ARUP Laboratories is a national reference ... laboratory research and development. ARUP offers an ... unique medical tests in clinical and anatomic ... ARUP Laboratories' clients include more than half ...
... ARUP Laboratories is a national reference laboratory ... research and development. ARUP offers an extensive ... medical tests in clinical and anatomic pathology. ... Laboratories' clients include more than half of ...
Medicine Products: