Navigation Links
Beware: Newly recognized heart cardiomyopathy is not always benign
Date:3/9/2013

Even though a newly recognized cardiomyopathy, which mainly impacts women, is typically treatable, Tako-tsubo cardiomyopathy can also be deadly when compounded by other co-morbidities, such as heart failure, according to a study being presented March 9 at the American College of Cardiology (ACC) Scientific Sessions.

This condition, formally known as Tako-tsubo cardiomyopathy (TTC) and informally known as stress cardiomyopathy or broken heart syndrome, has abrupt onset of symptoms and is characterized by a distinctive left ventricular (LV) contraction profile. Ninety percent of the time, this condition affects women, who are usually middle aged and older, and the condition usually is triggered by a stressful event.

"Although TTC is typically reversible and considered to have favorable clinical outcomes, we have identified an important subset of patients, particularly those with severe heart failure and hypotension, who can have a substantial mortality risk," says the study's lead author Scott W. Sharkey, MD, a research cardiologist at the Minneapolis Heart Institute Foundation and a physician at the Minneapolis Heart Institute at Abbott Northwestern Hospital in Minneapolis. "It's also important that physicians are aware this is not a rare a condition, as it is present in nearly 10 percent of women who present to the hospital with suspected heart attacks."

MHIF researchers reviewed 250 TTC patients who presented to the Minneapolis Heart Institute at Abbott Northwestern Hospital between 2001 and 2012. Then, they segregated those TTC patients presenting with particularly severe heart failure and very low pressure, or hypotension (systolic blood pressure < 100 mm Hg), who required supportive treatment.

They found that severe hypotensive heart failure occurred in 45 patients. In this subset, 9 female patients died in-hospital despite aggressive treatment intervention, representing the only TTC-related hospital deaths in the 250 patient cohort.

Therefore, Sharkey and his colleagues concluded that TTC is not necessarily a benign condition. Severe hypotensive heart failure of severity necessitating vasopressor and/or intra-aortic balloon pump occurs in nearly 20 percent of patients. Also, all TTC-related hospital deaths occurred in the hypotensive heart failure subgroup with an overall mortality of 3.5 percent.

Importantly, triggering physical stressors related to severe co-morbid non-cardiac conditions (8) or advanced age (1) were present in all 9 non-survivors, Sharkey notes.

"Unfortunately, there are not any guidelines or criteria to instruct diagnosis and treatment of these patients at this time," says Sharkey. "Therefore, this study could be a starting point for this process, as it provides a more complete profile of the clinical spectrum of TTC and provides useful guidance for the effective management of these acutely ill patients."

To raise additional awareness and improve care of these patients, he adds that guidelines would be helpful at this time, in order to standardize diagnosis and treatment across varied healthcare settings.


'/>"/>

Contact: Steve Goodyear
sgoodyear@mhif.org
612-863-1658
Minneapolis Heart Institute Foundation
Source:Eurekalert

Related medicine news :

1. Newly Hired Emergency Workers Who Witness Trauma May Struggle Afterward
2. Nearly 1 in 4 women newly diagnosed with breast cancer
3. Zephanol-HP Takes Top Scores in Newly-Released Independent Diet Pill Research
4. HealthCompare Urges the Newly Increasing Numbers of 1099 Employees to Seek Health Insurance Coverage They Need
5. Newly Published Graph Discloses the Dangers and Deaths Linked with Digestive Disease
6. Newly Published by Atlantic Information Services — Dual Eligibles: The New Growth Opportunities Ahead for Health Plans
7. Newly approved oral medication slows rheumatoid arthritis joint damage
8. Neurological Wellness Center Pays Tribute to Newly Released Study Announcing TBI Treatment Breakthrough
9. Newly Updated 'Critical Bench' Teaches People How to Gain Muscle, Says Tony Nguyen
10. Newly Launched Blenderreviews101.com - The Best and Complete Resource for Blender Reviews
11. Newly Released “H Miracle” Can Teach People How to Cure Hemorrhoids, Says Health Review Center
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:5/26/2017)... (PRWEB) , ... May 26, 2017 , ... Yisrayl Hawkins, ... new publication this week that is focusing on the Peace Agreements being discussed by ... Middle East sprint in a race to try to speed up peace talks in ...
(Date:5/26/2017)... ... May 26, 2017 , ... “THE FLINTHILLS FAMILY-Our Journey to the Cross”: the personal journey of ... Cross” is the creation of published authors, Bob and Margaret Massey. Bob Massey is ... is "panther quick and leather tough." His love for others is apparent in all ...
(Date:5/24/2017)... ... 2017 , ... Last month, representatives from Rendina Healthcare Real ... officials to celebrate the grand opening of the 87,000 square foot medical office/ICU ... its ongoing relationship with RWJBarnabas Health, New Jersey’s largest health system. Two years ...
(Date:5/24/2017)... ... May 24, 2017 , ... Drs. Nicholas Rallis ... have now spent 10 years as clinical instructors for the reputable Full Mouth ... Dentistry. Through the program, private practitioners receive cutting-edge clinical training and learn how ...
(Date:5/24/2017)... ... 24, 2017 , ... Dr. Curry Leavitt, a noted periodontist ... Practice) continuing education (CE) series. As a compassionate and dedicated clinician, Dr. Curry ... numerous CE courses each year. His recent course, Course II of HP3, focused ...
Breaking Medicine News(10 mins):
(Date:5/10/2017)... Mass., May 10, 2017 Hologic, Inc. (Nasdaq: ... results for the fiscal second quarter ended April 1, ... of $1.84 increased 666.7% compared to the prior year ... resulted in a significant gain, while non-GAAP diluted EPS ... 3.2%, or 3.8% in constant currency terms.  Excluding the ...
(Date:5/9/2017)... 2017 Zimmer Biomet Holdings, Inc. (NYSE and ... announced it has earned a spot on Forbes, ... Company was ranked among 500 U.S. employers as well ... Equipment and Services. The annual Forbes ... independent survey of over 30,000 employees across 25 industries. ...
(Date:5/8/2017)... 2017  Diplomat Pharmacy, Inc. (NYSE: DPLO)., has completed ... a health care service center company based in ... in relationship management programs for leading pharmaceutical manufacturers and ... WRB will join Envoy Health Management, LLC ... manufacturers, biotech firms, and other service companies. Together, WRB ...
Breaking Medicine Technology: