Navigation Links
Antihistamine Meds May Raise Risk for Diarrheal Illness
Date:3/29/2013

FRIDAY, March 29 (HealthDay News) -- Patients who take antihistamines to reduce stomach acid are at increased risk for infection with Clostridium difficile, a common cause of diarrhea, a new study finds.

Researchers reviewed the findings of 33 previous studies that looked at C. difficile and antihistamines used to suppress stomach acid. People who took over-the-counter antihistamine drugs did not have a significantly increased risk of C. difficile infection.

However, a clear link existed between histamine 2 receptor antagonists -- a specific class of antihistamines -- and C. difficile infection. The risk for people on these drugs -- also known as H2 blockers -- was greatest for hospitalized patients receiving antibiotics, said the researchers from the Mayo Clinic in Rochester, Minn.

The study was published online March 27 in the journal PLoS One.

"It's not clear why these antihistamines increase the risk of C. difficile infection, because gastric acid does not affect C. difficile spores," senior author Dr. Larry Baddour, an infectious diseases expert, said in a Mayo Clinic news release. "However, it may be that vegetative forms of C. difficile, which are normally killed by stomach acid, survive due to use of stomach acid suppressors and cause infection."

The researchers said their findings highlight the need for careful use of histamine 2 receptor antagonists in hospitalized patients, and suggest that reducing the use of these drugs could significantly lower the risk of C. difficile infections.

Although the study tied use of these drugs to higher risk of diarrheal illness, it did not establish a cause-and-effect relationship.

More information

The American Academy of Family Physicians has more about Clostridium difficile infections.

-- Robert Preidt

SOURCE: Mayo Clinic, news release, March 27, 2013


'/>"/>
Copyright©2012 ScoutNews,LLC.
All rights reserved

Related medicine news :

1. Side Plank Leg Raises Video Revealed by Bodyweight Torch
2. Isolation, Loneliness May Raise Death Risk for Elderly
3. Stress During Pregnancy May Raise Heart Defect Risk for Baby
4. Michigan Lupus Foundation Texas Hold 'Em Tournament Raises Thousands for Lupus Support, Education & Research
5. Having Older Grandfather May Raise Childs Autism Risk: Study
6. Stroke Before Age 50 Linked to Raised Risk of Early Death
7. Chuback Medical Group Raises Awareness for the Serious Vein Condition Deep Vein Thrombosis
8. New Guidelines Raise Safety Bar on Concussions
9. Night Shift Linked to Raised Risk of Ovarian Cancer
10. Major Bleeds After Heart Procedures May Raise Death Risk: Study
11. Mental Illness May Raise Risk of Being Murdered
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:6/25/2016)... ... ... closing of Bruton Memorial Library on June 21 due to a possible lice infestation, as ... of head lice: the parasite’s ability to live away from a human host, and to ... one in the event that lice have simply gotten out of control. , As lice ...
(Date:6/25/2016)... (PRWEB) , ... June 25, 2016 , ... As a ... Magna Cum Laude and his M.D from the David Geffen School of Medicine at ... returned to Los Angeles to complete his fellowship in hematology/oncology at the UCLA-Olive View-Cedars ...
(Date:6/25/2016)... ... 25, 2016 , ... Conventional wisdom preaches the benefits of moderation, whether it’s ... setting the bar too high can result in disappointment, perhaps even self-loathing. However, those ... goal. , Research from PsychTests.com reveals that behind the tendency to ...
(Date:6/24/2016)... (PRWEB) , ... June 24, 2016 , ... June 19, ... the dangers associated with chronic pain and the benefits of holistic treatments, Serenity ... who are suffering with Sickle Cell Disease. , Sickle Cell Disease (SCD) is a ...
(Date:6/24/2016)... ... 24, 2016 , ... Global law firm Greenberg Traurig, P.A. announced that 20 ... by their peers for this recognition are considered among the top 2 percent of ... honors as members of this year’s Legal Elite Hall of Fame: Miami Shareholders ...
Breaking Medicine News(10 mins):
(Date:6/23/2016)... , June 23, 2016 Research and ... Global Market - Forecast to 2022" report to their ... treatment method for the patients with kidney failure, it replaces ... fluid from the patient,s blood and thus the treatment helps ... and chloride in balance. Increasing number of ...
(Date:6/23/2016)... Roche (SIX: RO, ROG; OTCQX: RHHBY) announced that it ... (procalcitonin) assay as a dedicated testing solution for people ... Roche is the first IVD company in the U.S ... assessment and management. PCT is a sepsis-specific ... blood can aid clinicians in assessing the risk of ...
(Date:6/23/2016)... WAYNE, Pa. , June 23, 2016 ... provider, will launch its next generation clinical outcomes platform, Bracket ... DIA Meeting held on June 26 – 30, 2016 in ... 6.0, the first electronic Clinical Outcome Assessment product of its ... DIA Booth #715. Bracket eCOA 6.0 is a ...
Breaking Medicine Technology: