Navigation Links
Antibiotic therapy reduces mortality by 68 percent in hemodialysis patients
Date:7/2/2014

DETROIT An antibiotic therapy known to reduce catheter-related bloodstream infections in hemodialysis patients has been shown for the first time to reduce mortality, according to a Henry Ford Health System study.

Researchers found that a low-dose "lock" solution of gentamicin/citrate reduced mortality by 68 percent compared to a solution of heparin, a blood-clotting therapy long considered the standard of care. Additionally, the gentamicin/citrate solution was associated with a 73 percent reduction in bloodstream infections compared to the heparin treatment.

Bloodstream infections are a leading cause of hospitalization and death in hemodialysis patients.

The findings are published online in the Clinical Journal of the American Society of Nephrology at http://bit.ly/1nZlCpd, and will appear in the journal's July print edition. An editorial accompanies the study.

Jerry Yee, M.D., division head of Nephrology and Hypertension at Henry Ford and the study's senior author, says the findings suggest the antibiotic therapy is a potential game-changer for hemodialysis treatment.

"Advances in treatment have been elusive over the years. Perhaps our study can be a starting point to change the paradigm as a standard of care," Dr. Yee says. "The gentamicin/citrate solution was shown to be both safe and effective."

For their prospective, observational study involving 749 patients from September 2008 to June 2011, researchers compared the two therapeutic solutions. There were 427 patients in the heparin study arm and 322 in the gentamicin/citrate arm. The solutions were administered using an antibiotic locking-technique that prevents catheter clotting and reduces infection.

Multiple studies have shown the benefit of using an antibiotic locking strategy for reducing bloodstream infections. However, the Centers for Disease Control and Prevention and Infectious Diseases Society of America do not recommend the use of the solutions amid concern of a potential antimicrobial resistance with gentamicin/citrate. However, Henry Ford researchers found that gentamicin resistance rates deceased two-fold.


'/>"/>

Contact: David Olejarz
David.Olejarz@hfhs.org
313-874-4094
Henry Ford Health System
Source:Eurekalert  

Related medicine news :

1. Antibiotics Linked to Retinal Detachment Risk
2. Researchers find evidence of banned antibiotics in poultry products
3. Study Finds Antibiotics Best for Appendicitis
4. FDA Seeks to Limit Antibiotics in Animal Feed
5. Probiotic Products May Prevent Antibiotic-Linked Diarrhea
6. Study Links Antibiotic to Slight Rise in Heart Patients Death Risk
7. Study shows antibiotic improves respiratory function in lung transplant patients
8. Antibiotic-Resistant Gonorrhea Spreading: WHO
9. A non-antibiotic approach for treating urinary tract infections
10. Trivedi Beef, LLC Announces Breakthrough Beef Industry Data without the use of Antibiotic Drugs, Hormones or Steroids
11. Study examines role of seasonal prescribing changes in antibiotic resistance
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Antibiotic therapy reduces mortality by 68 percent in hemodialysis patients
(Date:3/28/2017)... CA (PRWEB) , ... March 28, 2017 , ... Silicon ... is proud to announce a new blog post about women’s hair loss. Although hair ... from hair loss as they age. Menopause or genetics can be two reasons a ...
(Date:3/28/2017)... ... March 28, 2017 , ... Thank you to all who attended Capio Partners ... This event was exclusive to providers and offered an opportunity to collaborate and network ... the Manchester Grand Hyatt where attendees gathered for a lively discussion on trends and ...
(Date:3/28/2017)... ... ... a thrilling adventure that reveals the mystery of Kevin’s purpose. “A Prophets Bones” is the ... had asked of him that he had neglected to do, but this was from God ... were some who would have felt themselves to be special and better than others due ...
(Date:3/27/2017)... (PRWEB) , ... March 27, 2017 , ... New patients ... Braasch for leading sleep apnea treatment, with or without a referral. Sleep apnea is ... which can include daytime sleepiness, morning headaches and chronic snoring. , Dr. Braasch ...
(Date:3/27/2017)... Eau Claire, WI (PRWEB) , ... March 27, ... ... currently accepting new patients for custom smile makeovers without requiring a ... needs including orthodontics, gum disease treatment, cosmetic dentistry and dental implants. Whether patients ...
Breaking Medicine News(10 mins):
(Date:3/27/2017)... , March 27, 2017  ImMAGE Biotherapeutics (OTCMKTS: ... immunotherapy successfully passed early toxicology and efficacy studies. The ... to target a specific protein, MAGE A, in an ... breast cancer. After 4 weeks of ... to show very little toxicity in a full toxicology ...
(Date:3/27/2017)... -- To mark the end of Save Your Vision Month, ... digital imaging solutions, will showcase Canon eye care devices during ... New York,s Jacob Javits Center from March 30 ... the American Optometric Association, is observed annually in March to ... exams. In recognition of this observance, Canon U.S.A. ...
(Date:3/27/2017)... -- FinancialBuzz.com News Commentary  ... Based on New Frontier Data,s sales forecasts in ... legal will generate $655 million in taxes on retail sales. Out ... such as Washington State,s 37% cannabis retail ... sales taxes that are applied on all retail sales. By 2020, ...
Breaking Medicine Technology: