Navigation Links
Aging cells lose their grip on DNA rogues
Date:1/30/2013

the organism or is it something that happens so late that by that point the organism has already accumulated so much age-associated damage?" he asked. "Then maybe this extra insult of transposition is not going to make a lot of difference."

The question matters, Sedivy says, because drugs might be able to suppress transposons in aging cells. Virtually all of the transposons of concern in mammals are so-called "retrotransposons" because they use RNA and an enzyme to copy themselves. Certain HIV drugs work by these enzymes called "reverse transcriptases." Remarkably, Sedivy said, the reverse transcriptase of the major human retrotransposons called "L1" has been shown by researchers to be inhibited by some HIV drugs widely used in the clinic.

"The prospects of coming up with an existing drug therapy is something we really need to think about seriously," he said. "We're definitely going to test that and in the future, if needed, we also should be able to design new drugs that are highly specific for L1."

Ultimate success would provide a way to restore order in the cells and forestall at least some of the molecular ravages of age.


'/>"/>
Contact: David Orenstein
david_orenstein@brown.edu
401-863-1862
Brown University
Source:Eurekalert  

Page: 1 2 3

Related medicine news :

1. Vaccine yielded encouraging long-term survival rates in certain patients with NSCLC
2. Social ties have mixed impact on encouraging healthy behaviors in low-income areas
3. Live imaging shows response to cancer drugs can be boosted by altering tumor microenvironment
4. MR enterography is as good or better than standard imaging exams for pediatric Crohns patients
5. Use of dedicated pediatric imaging departments for pediatric CT reduces radiation dose
6. Joslin scientists identify important mechanism that affects the aging process
7. Low-dose whole-body CT finds disease missed on standard imaging for patients with multiple myeloma
8. Staging and risk stratification of thyroid cancer improved with SPECT/CT
9. Study examines necessity of additional imaging in PET/CT oncologic reports
10. Self-Managing COPD Might Pose Risks, Study Suggests
11. CNIO scientists successfully test the first gene therapy against aging-associated decline
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Aging cells lose their grip on DNA rogues
(Date:11/26/2014)... 26, 2014 The report “Laboratory ... Mode (On-premise, Hosted, SaaS), End User Labs (Clinical, ... Component (Software, Services) - Global Forecast to 2019” ... restraints, challenges, opportunities, current market trends, and strategies ... and forecasts of the revenue and market growth. ...
(Date:11/26/2014)... November 26, 2014 The Maryland ... for the tenth annual MEDA Awards, which, sponsored ... excellence in Maryland. “The MEDA Awards recognize the ... to the state. We encourage our members to ... making a positive economic impact in the state ...
(Date:11/26/2014)... The family foundation of Best Buy founder, Richard ... Foundation (Meso Foundation), half of which will be specifically ... Program . The focus area of the Richard M. ... organizations that can generate transformational results in education, human ... and chairman emeritus of Best Buy Co., Inc., the ...
(Date:11/26/2014)... 2014 The Deptford Center for ... a partnership designed to improve the quality of ... failure (CHF) patients in the South Jersey area. ... Cardiology team will help CHF patients manage their ... partnership pairs the Cardiac Recovery program at the ...
(Date:11/26/2014)... Increasing demand for diagnostic imaging ... surgeries has paved way for consequent increase in ... various types of cancers and cardiac diseases globally ... for these owing to their use in diagnosing ... market can also be attributed to advancements in ...
Breaking Medicine News(10 mins):Health News:Laboratory Information Systems Market by Type, Delivery Mode & End Users is Estimated to Reach $1,806.1 Million by 2019 - New Research Report by MarketsandMarkets 2Health News:Laboratory Information Systems Market by Type, Delivery Mode & End Users is Estimated to Reach $1,806.1 Million by 2019 - New Research Report by MarketsandMarkets 3Health News:Laboratory Information Systems Market by Type, Delivery Mode & End Users is Estimated to Reach $1,806.1 Million by 2019 - New Research Report by MarketsandMarkets 4Health News:Maryland Economic Development Association Seeking Submissions for 2015 Awards 2Health News:Best Buy Founder’s Family Foundation Donates $100,000 to Organization Fighting Deadly Cancer 2Health News:Best Buy Founder’s Family Foundation Donates $100,000 to Organization Fighting Deadly Cancer 3Health News:Advanced Heart Failure Recovery Program comes to Deptford Center for Rehabilitation and Healthcare 2Health News:Advanced Heart Failure Recovery Program comes to Deptford Center for Rehabilitation and Healthcare 3Health News:Contrast Media Injectors Market To 2020 - Global Industry, Growth, Size, Share, Trends, Analysis And Forecast To 2020 Research Report By Grand View Research, Inc. 2Health News:Contrast Media Injectors Market To 2020 - Global Industry, Growth, Size, Share, Trends, Analysis And Forecast To 2020 Research Report By Grand View Research, Inc. 3
... be formally assessed to determine whether they would benefit from ... AMA Vice President and paediatric psychiatrist, Dr Choong-Siew Yong, said ... specific early interventions before and soon after birth, and until ... a positive impact on a child’s mental and physical health,” ...
... enteritidis is a type of salmonella bacteria.It is usually found ... //reports that this bacteria is now found more often in ... show a fourfold increase of salmonella enteritidis on chicken meat., ... 40,000 people every year with an annual death toll of ...
... teen-age smoking finds there is no solid evidence about ... have started. // ,Because one-third of smokers take ... percent before age 21, most previous studies of youth ... ,“There is not yet sufficient evidence to test ...
... pigs has been identified by scientists in South Korea – ... //microbiology, following the findings of J.J. Shin and colleagues at ... pathogen, the H3N1 influenza A virus that can be found ... reassortment of influenza viruses. The virus, which was first identified ...
... and Brain Research Centre at Canada's University //of British ... genetic predisposition to Alzheimer’s disease. , ,During the ... captivity marked by low-oxygen levels for about 16 hours ... was subject to normal levels of oxygen. ...
... A century ago this month, German psychiatrist Alois ... //which ultimately came to bear his name. While ... develop treatments have progressed significantly in recent years, ... ,A new research tool developed by Susan Liebman, ...
Cached Medicine News:Health News:Early Intervention to Improve Kids’ Healt 2Health News:No Proven Programs to Help Teens Quit Smoking 2Health News:No Proven Programs to Help Teens Quit Smoking 3Health News:Yeast Model Shows Promise as Alzheimer's Test 2
(Date:11/26/2014)... and NEW YORK and ... As the leading distributor of market intelligence, MarketResearch.com is ... report by IQ4I Research and Consultancy focusing on the ... more about IQ4I Research visit: http://www.marketresearch.com/land/publisher.asp?vendorid=4023&progid=86891 . ... Pharmaceutical Ingredients Global Market – Forecast to 2020 ...
(Date:11/26/2014)... , Nov. 25, 2014  Medtronic,s ... has been widely discussed in the media ... also creating a stronger leading player in one ... Kalorama Information.  The healthcare market research firm said ... will feature a diverse set of solutions spanning ...
(Date:11/26/2014)... Nov. 25, 2014  Breckenridge Pharmaceutical, Inc. announced ... ANDA agreement with Pii (Pharmaceutics International, Inc.) ( ... Breckenridge and Pii expect to develop and commercialize ... agreement, Pii will develop, manufacture and supply the ... products under its own label.  The drugs, comprised ...
Breaking Medicine Technology:MarketResearch.com: Active Pharmaceutical Ingredient Market to Reach $175 Billion by 2020 Says IQ4I Report 2MarketResearch.com: Active Pharmaceutical Ingredient Market to Reach $175 Billion by 2020 Says IQ4I Report 3Medtronic - Covidien: Beyond Taxes, Deal Will Create Patient Monitoring Power, according to Kalorama Information 2Medtronic - Covidien: Beyond Taxes, Deal Will Create Patient Monitoring Power, according to Kalorama Information 3Breckenridge Pharmaceutical signs Multi-Product Generic Agreement with Pharmaceutics International, Inc. 2
Compact instrument that quickly dries racks of slides using warm air....
Liquichek Blood Gas Plus EGL Control is an aqueous product used to monitor the measurement of pH, pCO2, pO2, electrolytes, glucose and lactate (lactic acid)....
Liquichek Cardiac Markers Control is a multi-analyte liquid control for monitoring cardiac assessment tests. Assayed values are available for major instruments....
Meter Trax Control is a whole blood quality control that can be used for glucose, hemoglobin and hematocrit testing on point of care instruments....
Medicine Products: