Navigation Links
Aging cells lose their grip on DNA rogues
Date:1/30/2013

the organism or is it something that happens so late that by that point the organism has already accumulated so much age-associated damage?" he asked. "Then maybe this extra insult of transposition is not going to make a lot of difference."

The question matters, Sedivy says, because drugs might be able to suppress transposons in aging cells. Virtually all of the transposons of concern in mammals are so-called "retrotransposons" because they use RNA and an enzyme to copy themselves. Certain HIV drugs work by these enzymes called "reverse transcriptases." Remarkably, Sedivy said, the reverse transcriptase of the major human retrotransposons called "L1" has been shown by researchers to be inhibited by some HIV drugs widely used in the clinic.

"The prospects of coming up with an existing drug therapy is something we really need to think about seriously," he said. "We're definitely going to test that and in the future, if needed, we also should be able to design new drugs that are highly specific for L1."

Ultimate success would provide a way to restore order in the cells and forestall at least some of the molecular ravages of age.


'/>"/>
Contact: David Orenstein
david_orenstein@brown.edu
401-863-1862
Brown University
Source:Eurekalert  

Page: 1 2 3

Related medicine news :

1. Vaccine yielded encouraging long-term survival rates in certain patients with NSCLC
2. Social ties have mixed impact on encouraging healthy behaviors in low-income areas
3. Live imaging shows response to cancer drugs can be boosted by altering tumor microenvironment
4. MR enterography is as good or better than standard imaging exams for pediatric Crohns patients
5. Use of dedicated pediatric imaging departments for pediatric CT reduces radiation dose
6. Joslin scientists identify important mechanism that affects the aging process
7. Low-dose whole-body CT finds disease missed on standard imaging for patients with multiple myeloma
8. Staging and risk stratification of thyroid cancer improved with SPECT/CT
9. Study examines necessity of additional imaging in PET/CT oncologic reports
10. Self-Managing COPD Might Pose Risks, Study Suggests
11. CNIO scientists successfully test the first gene therapy against aging-associated decline
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Aging cells lose their grip on DNA rogues
(Date:9/2/2015)... ... 2015 , ... Pentec Health, Inc., a national leader in outsourced pharmacy services, ... consecutive year. Less than 5 % of this year’s 5000 honorees share the “six-time” ... Pentec’s 3-year revenue growth rate of 65% sustained its most recent achievement. As an ...
(Date:9/2/2015)... ... September 02, 2015 , ... Dr. Robert G. ... he is now certified in “Systema”: a Russian martial art system that is also ... , Systema , which dates back to the 10th century, is a ...
(Date:9/2/2015)... ... September 02, 2015 , ... Mobile working is increasingly more important, as business ... everywhere new mobile apps are being launched, and mobile device usage as a whole ... of their work and personal lives. What's more people are expecting mobile versions of ...
(Date:9/1/2015)... Spring Lake, NJ (PRWEB) , ... September 01, ... ... physician, has a reputation for the telling the truth about medicine and health, ... has created a video blog, where he plans to regularly debunk certain misconceptions ...
(Date:9/1/2015)... Paul- Eagan (PRWEB) , ... September 01, 2015 , ... For many men, the first ... chin. Men were often forced to wear a looser fitting shirt with a collar ... their neck, sliding a finger between their collar and skin all day because it’s uncomfortable. ...
Breaking Medicine News(10 mins):Health News:Pentec Health Once Again Named One of the Fastest-Growing Private Companies in America 2Health News:Dr. Robert G. Schwartz Achieves Certification in Russian Martial Art “Systema” and Focuses on Integrating Techniques & Principles into Health Care Delivery 2Health News:Dr. Robert G. Schwartz Achieves Certification in Russian Martial Art “Systema” and Focuses on Integrating Techniques & Principles into Health Care Delivery 3Health News:New Mobility Experience From Winscribe 2Health News:New Mobility Experience From Winscribe 3Health News:Dr. Michael Rothman, NJ’s Leading Holistic Doctor, Presents a Video Blog that Discusses the Most Confusing and Interesting Current Medical Topics 2Health News:Getting Rid of Double Chins: New FDA Approved Kybella Treatment Proving Very Popular Among Professional Men at Crutchfield Dermatology 2
... excess weight worsens disease , THURSDAY, June 4 (HealthDay News) ... as many experts have thought, but it could dampen the ... , Inhaled corticosteroids are the most widely prescribed drugs to ... whom are overweight or obese. , "It raises the concern ...
... N.J., June 4 Cambrex Corporation (NYSE: CBM ... New York Stock Exchange ("NYSE") informing the Company that it ... As announced by the Company on April 14, 2009, ... standards because its average market capitalization over a consecutive 30-day ...
... night, the America,s Health Insurance Plans (AHIP) Foundation paid ... Group Health Cooperative of South Central Wisconsin, and L.A. ... designed to improve the health and environment of communities ... health plans of working with local partners in a ...
... , "Headache U" is first educational program of its kind, matches ... , CHICAGO, June 4 The National Headache Foundation (NHF) ... headache education program of its kind designed to help people with ... beginning today on the NHF website at http://www.headaches.org/headacheu/ ...
... , MIAMI, June 4 St. Jude Children,s Research Hospital(R) ... by honoring Tommy and Thalia Mottola on May ... Estefan , co-host of the popular Univision show El ... the 2009 Al-Rashid Hope Award for their commitment to children,s ...
... could lead to treatment or prevention , THURSDAY, June 4 ... a key role in cell death in Huntingdon,s disease, a ... intellectual functioning. , The discovery raises hope that drugs could ... a study in the June 5 issue of Science ...
Cached Medicine News:Health News:Obesity May Dampen Response to Asthma Meds 2Health News:AHIP Foundation Announces 2009 Community Leadership Awards 2Health News:New Online Tool Helps People With Headache Take Control, Get Relief 2Health News:New Online Tool Helps People With Headache Take Control, Get Relief 3Health News:New Online Tool Helps People With Headache Take Control, Get Relief 4Health News:Photos: Tommy & Thalia Mottola Honored at 7th Annual FedEx/St. Jude Angels & Stars Gala 2Health News:Photos: Tommy & Thalia Mottola Honored at 7th Annual FedEx/St. Jude Angels & Stars Gala 3Health News:Discovery Sheds Light on Huntington's Disease 2Health News:Discovery Sheds Light on Huntington's Disease 3
(Date:9/1/2015)... Delaware , United States , Sept. ... "Invion"), is pleased to announce that it has entered into ... investor in the United States in ... million ("Placement") by the issue of 71,500,000 million fully-paid ordinary ... The Company has also agreed to grant ...
(Date:9/1/2015)... OR YEHUDA, Israel , Sept. 1, ... HTWR ), a leading innovator of less invasive, miniaturized ... advanced heart failure, announced today that it has entered ... Ltd . ("Valtech").  Valtech is a privately held company ... transcatheter valve repair and replacement devices for the treatment ...
(Date:9/1/2015)... SPRINGDALE, Ark. , Sept. 1, 2015 NOWDiagnostics Inc., ... completed its acquisition of ZBx Corporation of Canada ... to its vision of a world where people have ... NOWDiagnostics manufactures and sells a line of unique blood-based ... simple-to-use, highly accurate tests for a variety of ailments ...
Breaking Medicine Technology:Invion Announces Private Placement to US Institutional Investor 2Invion Announces Private Placement to US Institutional Investor 3HeartWare International Enters Into Definitive Agreement To Acquire Valtech Cardio, Ltd. 2HeartWare International Enters Into Definitive Agreement To Acquire Valtech Cardio, Ltd. 3HeartWare International Enters Into Definitive Agreement To Acquire Valtech Cardio, Ltd. 4HeartWare International Enters Into Definitive Agreement To Acquire Valtech Cardio, Ltd. 5HeartWare International Enters Into Definitive Agreement To Acquire Valtech Cardio, Ltd. 6HeartWare International Enters Into Definitive Agreement To Acquire Valtech Cardio, Ltd. 7HeartWare International Enters Into Definitive Agreement To Acquire Valtech Cardio, Ltd. 8HeartWare International Enters Into Definitive Agreement To Acquire Valtech Cardio, Ltd. 9HeartWare International Enters Into Definitive Agreement To Acquire Valtech Cardio, Ltd. 10NOWDiagnostics Inc. Acquires Canada's ZBx Corporation 2NOWDiagnostics Inc. Acquires Canada's ZBx Corporation 3
... from Phase II/III Study Presented at Heart Failure Congress ... , SAN MATEO¿ Calif.¿ June 1 Corthera Inc. ... conducted from Pre-RELAX-AHF, the Phase II portion of a ... relaxin, the company,s investigational drug for the treatment of ...
... ORLANDO, Fla., May 31 Eli Lilly and Company ... addition of Lilly,s GEMZAR(R) (gemcitabine HCl for injection) to ... increase in progression-free survival at three years for women ... the world,s second most commonly diagnosed women,s cancer, and ...
Cached Medicine Technology:Results and Additional Analyses From Study Show That Corthera's Relaxin for Acute Heart Failure is the Strongest Predictor of Improved Longer-Term Outcomes Following Hospital Discharge When Compared to Other Variables 2Results and Additional Analyses From Study Show That Corthera's Relaxin for Acute Heart Failure is the Strongest Predictor of Improved Longer-Term Outcomes Following Hospital Discharge When Compared to Other Variables 3Results and Additional Analyses From Study Show That Corthera's Relaxin for Acute Heart Failure is the Strongest Predictor of Improved Longer-Term Outcomes Following Hospital Discharge When Compared to Other Variables 4Results and Additional Analyses From Study Show That Corthera's Relaxin for Acute Heart Failure is the Strongest Predictor of Improved Longer-Term Outcomes Following Hospital Discharge When Compared to Other Variables 5Study Showed Lilly's GEMZAR(R) (gemcitabine HCl for injection) Improved Progression-Free Survival in Cervical Cancer Patients 2Study Showed Lilly's GEMZAR(R) (gemcitabine HCl for injection) Improved Progression-Free Survival in Cervical Cancer Patients 3Study Showed Lilly's GEMZAR(R) (gemcitabine HCl for injection) Improved Progression-Free Survival in Cervical Cancer Patients 4Study Showed Lilly's GEMZAR(R) (gemcitabine HCl for injection) Improved Progression-Free Survival in Cervical Cancer Patients 5Study Showed Lilly's GEMZAR(R) (gemcitabine HCl for injection) Improved Progression-Free Survival in Cervical Cancer Patients 6
... standard, corrected curve trial lenses are ground with ... Marco refractors and are invaluable in treating low ... other manufacturers contain a disproportionately large number of ... expensive to produce, and fewer lenses in the ...
The LM-990A is the most completely automatic lensemeter ever created. It even measured monocular and binocular PD automatically....
... has made the LM-770 the easiest ... Technicians can be trained to operate ... instruction. The instrument tells the user ... A flashing indicator alerts the user ...
... designed to perform precise and accurate ... one-third the space of traditional examinations. ... refractors, automatic or digital lensmeters and ... EPIC enables the operator to call ...
Medicine Products: