Navigation Links
Advances in delivery of therapeutic genes to treat brain tumors
Date:6/27/2011

New Rochelle, NY, June 27, 2011Novel tools and methods for delivering therapeutic genes to cells in the central nervous system hold great promise for the development of new treatments to combat incurable neurologic diseases. Five of the most exciting developments in this rapidly advancing field are presented in a series of articles in the June issue of Human Gene Therapy, a peer-reviewed journal published by Mary Ann Liebert, Inc. (www.liebertpub.com). The articles are available free online at www.liebertpub.com/hum

A review article by Betley and Sternson, "Adeno-Associated Viral Vectors for Mapping, Monitoring, and Manipulating Neural Circuits," highlights the latest genetic tools that are enabling cell type-specific delivery of transgenes for studying the structure and function of neuronal circuits.

Ryu et al. report on the successful use of stem cells derived from human umbilical cord blood to deliver a novel therapeutic geneinterleukin-12to the brain for long-term anti-tumor activity against gliomas, a deadly type of brain tumor. Their innovative strategy is presented in the research report "Gene Therapy of Intracranial Glioma Using Interleukin 12-Secreting Human Umbilical Cord Blood-Derived Mesenchymal Stem Cells."

"High-Density Lipoprotein Facilitates In Vivo Delivery of α-Tocopherol-Conjugated Short-Interfering RNA to the Brain" by Uno et al. describes a combination strategy for dramatically improved delivery of siRNAs to the brain to silence genes involved in neurological disease.

Loss of the neurotrophic factor GDNF contributes to the development of neuropathic pain caused by trauma or neurodegenerative disease. Shi et al. present data to support this link and demonstrate the potential to replace GDNF via intramuscular gene delivery in the article "Glial Cell Line-Derived Neurotrophic Factor Gene Transfer Exerts Protec
'/>"/>

Contact: Vicki Cohn
vcohn@liebertpub.com
914-740-2100
Mary Ann Liebert, Inc./Genetic Engineering News
Source:Eurekalert  

Page: 1 2

Related medicine news :

1. New advances in lipid genetics lead to better detection and prevention of major diseases
2. Led by advances in chemical synthesis, scientists find natural product shows pain-killing properties
3. Society of Interventional Radiology addresses radiation safety, advances best practices
4. Experts to discuss advances in dental sleep medicine treatments for sleep-disordered breathing
5. UT Southwestern research advances fight against kidney cancer
6. Research presented at 2011 GU Cancers Symposium highlights advances in treatment of prostate cancer
7. RIC study suggests researchers are entering a new era of advances in brain research
8. Long-shot discovery may lead to advances in treating anxiety, memory disorders
9. Roundup: 2010 Advances in Heart Disease and Stroke Care
10. Ovarian cancer advances when genes are silenced
11. Blood Cancer Advances May Improve Survival
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Advances in delivery of therapeutic genes to treat brain tumors 
(Date:3/31/2015)... 31, 2015 Horizon Blue Cross Blue ... its efforts to combat health insurance fraud resulted in ... of monies recovered and losses avoided -- in 2014. ... Horizon BCBSNJ created its fraud fighting, Special Investigations Unit ... efforts have saved members $261 million. , “Our ...
(Date:3/31/2015)... Altima Technologies, Inc., the maker ... documenting and diagramming data center assets and audio-video ... Manufacturer / Device Model, Dell N3000 Series, Dell ... Dell PowerEdge r630, Cisco Catalyst 3850 Series, HP ... 100K, VMAX 200K, VMAX 400K , “With NetZoom ...
(Date:3/31/2015)... The Oliver Law Group, who ... notes that filings for testosterone lawsuits that allege ... complications associated with testosterone therapy products such as ... steady pace. The website for the U.S. District ... lawsuits have been centralized, shows 1,291 testosterone lawsuits ...
(Date:3/31/2015)... (PRWEB) March 31, 2015 When SIGVARIS launched ... company’s most successful product launch to date. Women immediately fell ... is giving women another reason to love EVERSHEER with the ... for spring. , Lavender mist pairs perfectly with a ... neutral outfits. For women looking to add a hint of ...
(Date:3/31/2015)... 2015 India Network Foundation , ... a travel advisory to all USA bound international travelers ... United States are higher than many other countries and ... For example, a coronary artery bypass graft costs ... about $34,358 . Visitors are advised to get ...
Breaking Medicine News(10 mins):Health News:Horizon Blue Cross Blue Shield of New Jersey Saves Members, Health System a Record $45.4 Million through Anti-fraud Efforts 2Health News:Altima Adds More Hardware Devices to its NetZoom™ Visio® Stencils Device Library 2Health News:Testosterone Lawsuit Filings Rise To Over 1,200 In Multidistrict Litigation Pending In Northern Illinois Federal Court Reports The Oliver Law Group 2Health News:Testosterone Lawsuit Filings Rise To Over 1,200 In Multidistrict Litigation Pending In Northern Illinois Federal Court Reports The Oliver Law Group 3Health News:Put Spring in Your Step with SIGVARIS’ Top Selling Sheer Hosiery Compression Therapy Brand 2Health News:India Network Foundation issues travel advisory to all US bound travelers on visitor health insurance requirements 2Health News:India Network Foundation issues travel advisory to all US bound travelers on visitor health insurance requirements 3
... February 16, 2011 An article published in a forthcoming ... of the first to provide evidence of the effectiveness ... suffering from posttraumatic stress disorder (PTSD). The study shows ... in PTSD symptoms after an average of seven treatment ...
... Sciences, National Academy of Engineering, Institute of Medicine, and National ... annual meeting of the American Association for the Advancement of ... Washington, D.C. Tribute to Stephen H. ... East (Renaissance Downtown), Stephen Schneider, a renowned climate scientist at ...
... 16, 2011 − One of the tough challenges a parent ... parent the surviving children, and the task begins immediately, according ... moment their child dies, parents are faced with the two ... a child and the ongoing, daily demands from their surviving ...
... HealthDay Reporter , TUESDAY, Feb. 15 (HealthDay News) ... when they,re first tested may not need to be screened ... new study suggests. Dutch researchers presenting the findings ... few men with a PSA below 3.0 ng/ml were likely ...
... newly diagnosed with Alzheimer,s disease or other dementias, and ... how to plan for the patient,s progressive loss of ... by a physician at the San Francisco VA Medical ... "When a patient is diagnosed with Alzheimer,s disease or ...
... -- Psychotherapy triggers changes in the brains of people ... Medication and psychotherapy are used to treat people with ... overwhelming fear of interacting with others and of being ... the neurological effects of psychotherapy (talk therapy) than on ...
Cached Medicine News:Health News:Innovative virtual reality exposure therapy shows promise for returning troops 2Health News:Media advisory -- events at AAAS 2Health News:Media advisory -- events at AAAS 3Health News:Media advisory -- events at AAAS 4Health News:Parenting after the death of a child a difficult balancing act: York U study 2Health News:PSA Test Cut-off Could Signal Low-Risk Prostate Cancer 2Health News:PSA Test Cut-off Could Signal Low-Risk Prostate Cancer 3Health News:Financial planning a key but neglected component of Alzheimer's care, say researchers 2Health News:'Talk Therapy' Can Alter Brain Activity, Research Shows 2
(Date:3/31/2015)... , March 31, 2015 ... "Life Science and Chemical Instrumentation Market (Chromatography, Electrophoresis, DNA ... Flow Cytometer, Incubator, Fume Hood, Centrifuge) - Global ... Life Science and Chemical Instrumentation Market is expected ... of 6.9% from 2014 to 2019. ...
(Date:3/31/2015)... March 31, 2015  SCILEX Pharmaceuticals, Inc., a company ... on the treatment of pain, today announced that ITOCHU ... ), a member of ITOCHU Corporation ( Tokyo ... leading sogo shosha (general trading companies) in ... SCILEX.  ICF has worked closely with SCILEX as an ...
(Date:3/31/2015)... -- Ariana Smith, a 17-year-old Taylor teen, became the first patient ... a part of the Detroit Medical Center (DMC), and the ... a revolutionary 3D printed heart model to aid heart specialists ... In November, 2014, Ariana,s mom Jacqueline Foster ... a test that checks for problems with the electrical activity ...
Breaking Medicine Technology:Life Science and Chemical Instrumentation Market Worth $48.84 Billion by 2019 2Life Science and Chemical Instrumentation Market Worth $48.84 Billion by 2019 3Life Science and Chemical Instrumentation Market Worth $48.84 Billion by 2019 4Life Science and Chemical Instrumentation Market Worth $48.84 Billion by 2019 5SCILEX Pharmaceuticals Announces Strategic Investment By ITOCHU CHEMICAL FRONTIER Corporation 2Taylor Teen Becomes First Patient in Michigan to Benefit From 3D Printed Heart Model to Treat Life-Threatening Aneurysm 2Taylor Teen Becomes First Patient in Michigan to Benefit From 3D Printed Heart Model to Treat Life-Threatening Aneurysm 3Taylor Teen Becomes First Patient in Michigan to Benefit From 3D Printed Heart Model to Treat Life-Threatening Aneurysm 4Taylor Teen Becomes First Patient in Michigan to Benefit From 3D Printed Heart Model to Treat Life-Threatening Aneurysm 5
... reference laboratory and a worldwide leader in ... an extensive test menu of highly complex ... anatomic pathology. Owned by the University of ... half of the nation's university teaching hospitals ...
... is a national reference laboratory and a ... development. ARUP offers an extensive test menu ... in clinical and anatomic pathology. Owned by ... include more than half of the nation's ...
... is a national reference laboratory and a ... development. ARUP offers an extensive test menu ... in clinical and anatomic pathology. Owned by ... include more than half of the nation's ...
... a national reference laboratory and a worldwide ... ARUP offers an extensive test menu of ... clinical and anatomic pathology. Owned by the ... more than half of the nation's university ...
Medicine Products: