Navigation Links
Abbott to Present Data on Novel Cancer Treatments at American Society of Clinical Oncology Annual Meeting
Date:5/15/2008

l-2 proteins, restoring cell death to cancerous cells. Additionally, the compounds were found to enhance the effects of chemotherapy and radiation used to treat other types of cancer, such as non-small cell lung cancer.

Kinase Inhibitors (ABT-869)

Many oncology researchers are currently developing agents that target kinases, a class of enzymes that are often overly activated in cancer cells. Inhibition of the appropriate kinases can suppress tumor growth by cutting off its blood supply.

Discovered by Abbott scientists, ABT-869 is an oral small molecule that provides simultaneously potent and specific inhibition of the VEGFR and PDGFR families that is in Phase I clinical trials for solid tumors and selected hematologic malignancies such as leukemia. Phase II trials for several tumor types began this year.

PARP Inhibitors (ABT-888)

DNA damaging agents remain some of the most successful treatments for cancer. The enzyme Poly(ADP-ribose)polymerase (abbreviated PARP) can help repair DNA damage caused by these agents used to treat cancer and render them ineffective. As PARP activity is often increased in cancer cells, it provides these cells with a survival mechanism.

ABT-888 is an oral PARP-inhibitor developed by Abbott researchers to prevent DNA repair in cancer cells and increase the effectiveness of common cancer therapies such as radiation and alkylating agents.

ABT-888 completed a Phase 0 trial for patients with refractory solid tumors and lymphoid malignancies, and has entered several Phase I trials. Preclinical data indicates ABT-888 has improved the effectiveness of radiation and many types of chemotherapy in animal models of cancer.

About Abbott Oncology

Abbott Oncology is committed to the discovery and development of innovative cancer treatments that enable patients to live longer and healthier lives. Abbott's oncology research is focused on developing more targeted, less toxic therapies than are cu
'/>"/>

SOURCE Abbott
Copyright©2008 PR Newswire.
All rights reserved

Page: 1 2 3 4 5 6

Related medicine news :

1. Abbott to Present at Citi Investment Research Global Health Care Conference
2. Abbott to Present at Morgan Stanley Global Healthcare Unplugged Conference
3. Abbott Announces HUMIRA(R) (adalimumab) Approved in Japan for the Treatment of Rheumatoid Arthritis
4. Abbott Reports Double-Digit Sales and Earnings Growth in First Quarter and Reaffirms Full-Year Growth Outlook
5. Innovative Diagnostic Instrument Introduced by Abbott for Low- to Mid-Volume Laboratory Market Segment
6. Abbott FreeStyle Freedom(R) Lite Blood Glucose Monitoring System Now Available With No Coding for People With Diabetes
7. Abbott Hosts Conference Call for First-Quarter Earnings
8. Takeda, Abbott Announce Plans to Conclude TAP Joint Venture
9. FDA Approves Abbotts FreeStyle Navigator(R) Continuous Glucose Monitoring System
10. Abbott Receives CE Mark for Smaller-Size XIENCE(TM) V Drug Eluting Stent
11. Abbott, Genentech and WEHI Collaborate to Research and Develop New Anti-Cancer Drugs
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:10/31/2014)... 31, 2014 FindSurrogateMother.com conveys ... gifts of life — building a family through surrogacy. ... mothers and donors with hopeful intended parents in turn ... , It’s a collective aptitude of surrogate mothers, intended ... and fertility clinics that help provide these connections — ...
(Date:10/31/2014)... Phoenix dentist , Dr. Christy, is now offering 10 ... need routine care or have a more in-depth dental health ... that necessary care. The right dental treatments can transform a ... treatments due to financial concerns. Throughout the month of November, ... by the team at Christy Dental Care. , According ...
(Date:10/31/2014)... Radiology and EMR Integration , “Surveys ... diagnostic imaging centers but Connectivity is Opportunity,” says ... “Differentiation is critical in all businesses today and ... the intense competition and the downward pressure on ... from the competition by fully integrating with the ...
(Date:10/31/2014)... -- A few simple steps can help make this weekend,s ... "Adjusting to the end of Daylight Saving Time in ... change in the spring. The main reason is because we ... Dr. Praveen Rudraraju, director of the Center for Sleep Medicine ... a hospital news release. The many Americans who are ...
(Date:10/31/2014)... By Dennis Thompson ... (HealthDay News) -- A full-court press involving all public ... required to quell the current West African epidemic, a ... burying the Ebola-infected dead in a hygienic way, immediately ... virus, and providing better protection for health care workers ...
Breaking Medicine News(10 mins):Health News:Over 800 New Surrogate Mother Members at FindSurrogateMother.com Helping Create Pathways to Parenthood 2Health News:Over 800 New Surrogate Mother Members at FindSurrogateMother.com Helping Create Pathways to Parenthood 3Health News:Phoenix Dentist, Dr. Christy, is Now Offering Ten Percent Off On All Dental Treatments for the Month of November 2Health News:Diagnostic Imaging of Salem Expects Growth Partnering with DigitalOne 2Health News:Make the Most of This Weekend's Time Change 2Health News:4 Steps Could Quell Ebola in West Africa, Researchers Say 2Health News:4 Steps Could Quell Ebola in West Africa, Researchers Say 3
... GREENVILLE, SC, Oct. 17 /PRNewswire/ - The numbers are ... developing countries have a,disability. "It,s not the impairment ... disabilities, but their exclusion from mainstream,social, economic and political ... "We have to work together to stand up ...
... Oct. 16 Children in the South Bay,suffering ... conditions can,now receive specialty care from Lucile Packard ... hospital,s new South Bay,Specialty Center in Los Gatos ... all the hallmarks of its parent institution. ...
... Oct. 16 AtriCure, Inc.,(Nasdaq: ATRC ), ... surgical,ablation products, today announced that results reporting on ... adopted to,treat atrial fibrillation (AF), were published in ... McClelland, an,electrophysiologist, and colleagues from the Oregon Heart ...
... Oct. 16 At the U.S. Food ... Advisory Committee,meeting today, the majority of members ... including Shire Pharmaceuticals, non-calcium FOSRENOL(R),(lanthanum carbonate), to ... blood) in chronic kidney disease (CKD) Stage ...
... Multi-Year Search and Advertising ... Distribution Agreements, WebMD Announces Third ... 16 WebMD Health Corp. (Nasdaq:,WBMD), the leading provider of health ... September 30,2007. Preliminary Results for the Three Months Ended September ...
... PARK, N.J., Oct. 16 HLTH Corporation,(Nasdaq: HLTH ... for,the three months ended September 30, 2007 at approximately ... addition, as previously announced, HLTH Corporation,s 84% owned,subsidiary, WebMD ... will also,release their financial results for the three months ...
Cached Medicine News:Health News:CBM USA stands up and speaks out to world leaders on the International Day for the Eradication of Poverty 2Health News:Packard Children's Hospital Opens New South Bay Specialty Clinic Bringing Specialty Care Close to Home 2Health News:Published Results Using AtriCure Minimally Invasive Products 2Health News:Published Results Using AtriCure Minimally Invasive Products 3Health News:FDA Advisory Committee Votes in Favor of Earlier Use of Phosphate Binders in Stage 4 Kidney Disease Patients With Hyperphosphatemia 2Health News:FDA Advisory Committee Votes in Favor of Earlier Use of Phosphate Binders in Stage 4 Kidney Disease Patients With Hyperphosphatemia 3Health News:FDA Advisory Committee Votes in Favor of Earlier Use of Phosphate Binders in Stage 4 Kidney Disease Patients With Hyperphosphatemia 4Health News:FDA Advisory Committee Votes in Favor of Earlier Use of Phosphate Binders in Stage 4 Kidney Disease Patients With Hyperphosphatemia 5Health News:FDA Advisory Committee Votes in Favor of Earlier Use of Phosphate Binders in Stage 4 Kidney Disease Patients With Hyperphosphatemia 6Health News:FDA Advisory Committee Votes in Favor of Earlier Use of Phosphate Binders in Stage 4 Kidney Disease Patients With Hyperphosphatemia 7Health News:WebMD Reports Preliminary Third Quarter Financial Results 2Health News:WebMD Reports Preliminary Third Quarter Financial Results 3Health News:WebMD Reports Preliminary Third Quarter Financial Results 4Health News:WebMD Reports Preliminary Third Quarter Financial Results 5Health News:WebMD Reports Preliminary Third Quarter Financial Results 6Health News:WebMD Reports Preliminary Third Quarter Financial Results 7Health News:WebMD Reports Preliminary Third Quarter Financial Results 8Health News:WebMD Reports Preliminary Third Quarter Financial Results 9Health News:WebMD Reports Preliminary Third Quarter Financial Results 10Health News:WebMD Reports Preliminary Third Quarter Financial Results 11Health News:HLTH Corporation Announces Third Quarter Earnings Release Date and Conference Call 2
(Date:10/31/2014)... MELBOURNE, Australia and BARCELONA , ... Pty Ltd (Multigate) was found to infringe two Australian patents ... offering for sale in Australia safety ... of 17.10.14 in Federal Court of Australia ... at http://www.austlii.edu.au/au/cases/cth/FCA/2014/1110.html . In the detailed ...
(Date:10/31/2014)... 2014 Electronic prescribing or E-Prescribing ... prescription related information between prescriber, dispenser and ... physician and nurse practitioner to transmit a ... occurs during pharmacy operations. E-Prescribing system has ... complete medical lists, conducts all security checks ...
(Date:10/30/2014)... , Oct. 30, 2014 /CNW/ - Atlantic Canadians will ... reached between Canada,s provinces and ... , President of the Canadian Generic Pharmaceutical Association (CGPA), ... comments while speaking at the Atlantic Summit on Healthcare ... , which is being hosted by the Public Policy ...
Breaking Medicine Technology:B. Braun Wins Patent Disputes Against Poly Medicure Ltd's Australian Distributor Multigate Medical Devices Pty. Ltd. and Spanish Distributor Dextromédica S. L. 2E-Prescribing Market - Global Industry Analysis, Size, Share, Growth, Trends and Forecast, 2013 - 2019 2Atlantic Canadians to Save $560-Million Through Unprecedented Three-Year Pan-Canadian Agreement on Generic Prescription Medicines 2Atlantic Canadians to Save $560-Million Through Unprecedented Three-Year Pan-Canadian Agreement on Generic Prescription Medicines 3
... 2011 Varian Medical Systems (NYSE: VAR ... cancer treatment technologies at the upcoming American Urological Association ... will sponsor a series of presentations covering emerging treatments ... Within the company,s exhibit, Varian will showcase its latest ...
... May 11, 2011 ViroPharma Incorporated (Nasdaq: ... today that Halozyme has granted ViroPharma an exclusive ... a proprietary drug delivery platform using Halozyme,s recombinant ... a C1 esterase inhibitor. Additionally, Halozyme has agreed not ...
Cached Medicine Technology:Varian Medical Systems to Exhibit Full Spectrum of Prostate Cancer Treatment Approaches at the American Urological Association Meeting in Washington, D.C. 2Varian Medical Systems to Exhibit Full Spectrum of Prostate Cancer Treatment Approaches at the American Urological Association Meeting in Washington, D.C. 3ViroPharma and Halozyme Announce Collaboration for Combination of Recombinant Human Hyaluronidase Enzyme (rHuPH20) Technology with C1 Esterase Inhibitor 2ViroPharma and Halozyme Announce Collaboration for Combination of Recombinant Human Hyaluronidase Enzyme (rHuPH20) Technology with C1 Esterase Inhibitor 3ViroPharma and Halozyme Announce Collaboration for Combination of Recombinant Human Hyaluronidase Enzyme (rHuPH20) Technology with C1 Esterase Inhibitor 4ViroPharma and Halozyme Announce Collaboration for Combination of Recombinant Human Hyaluronidase Enzyme (rHuPH20) Technology with C1 Esterase Inhibitor 5ViroPharma and Halozyme Announce Collaboration for Combination of Recombinant Human Hyaluronidase Enzyme (rHuPH20) Technology with C1 Esterase Inhibitor 6ViroPharma and Halozyme Announce Collaboration for Combination of Recombinant Human Hyaluronidase Enzyme (rHuPH20) Technology with C1 Esterase Inhibitor 7
... for optimum patient comfort. The Nylon Finger Trap ... firm grip. ISI Nylon Finger Traps create a ... with the ISI Digi Grip or ISI Advanced ... available in non-sterile packs and come in five ...
... The CMIS Telemetry System is a ... of hospitals which require monitoring and ... facilities are able to monitor patients ... ambulatory transmitters and wireless bedsides. Now, ...
ISI Self-Supporting Arm Table offers the easy accessibility for surgeons, technicians and equipment during upper extremity surgeries....
MagPrep® Streptavidin Beads are encapsulated super-paramagnetic polystyrol particles coated with streptavidin. The beads have a diameter of 1 m and are provided as a stabilized aqueous suspensio...
Medicine Products: