Navigation Links
ASU leads $5 million NIH-sponsored research initiative to advance diabetes care and treatment
Date:11/1/2011

inical studies to advance the difficult search for markers that may be useful for both diagnosis and for assessing potential new drug therapies."

The study will examine and validate biomarkers in people with diabetes, some of whom will have had a heart attack. It is unlikely that a single biomarker will have enough predictive power to assess heart attack risk; rather, panels of biomarkers will be needed to identify drug targets.

"There is a great need for more-effective biomarkers of macrovascular complications of diabetes and for surrogate indicators of favorable response to potential diabetes therapies," said Peter Reaven, M.D., who will oversee the selection of target biomarkers and clinical work, including patient recruitment at the Phoenix VA Health Care System. "Our goal is to identify novel proteins and relevant protein modifications that reflect many of the critical mechanisms that underlay vascular disease in diabetes to develop a more comprehensive panel of biomarkers. One advantage to our team approach is that it will integrate, from the very beginning, the many aspects and disciplines required for a pipeline of biomarker discovery, validation and translation." Pfizer will play a key role in translating prognostic biomarkers of cardiovascular disease risk for decision-making during drug development for type 2 diabetes.

"Prognostic markers of cardiovascular disease risk have been an essential need for type 2 diabetes drug development ever since Nissen published his influential report suggesting some drugs may increase heart attack rates," said Jim Pearson, Ph.D., head of Personalized Medicine at Pfizer in Kalamazoo, MI. "The FDA now requires patients with a higher risk for cardiovascular events to be enrolled in Phase III clinical trials for two years instead of three-to-six months. The problem is that a useful directed proteomics CVD risk panel has yet to be translated. A biomarker panel that is more comprehensive than HbA1c
'/>"/>

Contact: Joe Caspermeyer
joseph.caspermeyer@asu.edu
480-727-0369
Arizona State University
Source:Eurekalert  

Page: 1 2 3

Related medicine news :

1. Rise in Vulvar Precancers Leads to New Guidelines
2. Project leads next decade of aging research across Europe
3. Project leads next decade of ageing research across Europe
4. X-ray protein probe leads to potential anticancer tactic
5. Insulation from public pressure leads to more accurate suicide reporting by death investigators
6. Unconventional hunt for new cancer targets leads to a powerful drug candidate for leukemia
7. Stronger social safety net leads to decrease in stress, childhood obesity
8. Drug improves brain function in condition that leads to Alzheimers
9. Drinking until you forget leads to injuries for college kids
10. 2 talks with teens leads to less marijuana use for at least a year
11. FSU scientist leads research on AIDS-related cancer
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
ASU leads $5 million NIH-sponsored research initiative to advance diabetes care and treatment
(Date:7/29/2014)... Society of America (GSA) the nation,s largest ... has chosen Barbara J. Bowers, PhD, RN, FAAN, of ... the Task Force on Minority Issues in Gerontology Outstanding ... to an individual who has exemplified outstanding commitment and ... aging. , The award presentation will take place at ...
(Date:7/29/2014)... likely to drink alcohol brands that advertise on television ... new and compelling evidence of a strong association between ... This is the conclusion of a new study from ... the Johns Hopkins Bloomberg School of Public Health and ... whether exposure to brand-specific alcohol advertising on 20 television ...
(Date:7/29/2014)... the nation,s largest interdisciplinary organization devoted to ... Lckenhoff, PhD, of Cornell University as the 2014 recipient ... Award in Behavioral and Social Gerontology. , This distinguished ... behavioral and social gerontology. Individuals who have received their ... award is given by GSA in conjunction with the ...
(Date:7/29/2014)... Nation Homelands, NY (PRWEB) July 29, 2014 ... Indian Nation have sent a letter to Washington NFL team ... representatives that opposition to the R-word racial slur is emanating ... date, the team and Snyder have yet to respond. ... release the full text of the letter, which was first ...
(Date:7/29/2014)... The report “Filling Equipment Market by Industry (Food, ... Weight), Process (Manual, Semi-Automatic, Automatic), Product (Solid, Semi-Solid, ... to 2019”, defines the filling equipment market and ... segments with analyses and projections of the market ... of value. It also identifies the driving and ...
Breaking Medicine News(10 mins):Health News:Bowers to receive GSA's 2014 Minority Mentorship Award 2Health News:Brand-specific television alcohol ads predict brand consumption among underage youth 2Health News:Löckenhoff earns GSA's 2014 Baltes Foundation Award 2Health News:Native American Groups Urge Washington Team Owner Dan Snyder to Stop Claiming Name Change Issue Driven by "Elites" Who Are Not People of Color 2Health News:Filling Equipment Market worth $8 Billion by 2019 - Report by MarketsandMarkets 2Health News:Filling Equipment Market worth $8 Billion by 2019 - Report by MarketsandMarkets 3Health News:Filling Equipment Market worth $8 Billion by 2019 - Report by MarketsandMarkets 4
... in UK it has been revealed that a increase in ... way we eat over the years.,The Mental Health Foundation and ... // have led to an increase in cases of depression, ... of the most important findings of the report was a ...
... Battle against Cancer, Singer, Actress and Diva Kylie Minogue has ... ,In a statement issued this week the Singer said ... // however her treatments were still ,continuing. ,It ... in the care ,of her family and friends after her ...
... Health Inc. told the National Heritage Insurance Co., the contractor ... accepted to cover its test. ,After this the ... $2.46 to $12.41 on Nasdaq. The company prepares oncotype DX ... is taking all the responsibility to cover the medical expenses ...
... applied for a financial grant amounting to approximately 110// ... for combating tuberculosis, said the Cabinet Minister. // ... Fund on AIDS, TB and Malaria, according to the ... approximately 15 and 30 million dollars would be approved ...
... scientific and research talent in frontier areas of research ... the preferred hub for knowledge-based industries. // ... to information and communication technology alone, but spans agriculture, ... space. ,India's efforts to become a superpower ...
... of the HIV drugs in the city of Vancouver in British ... 125 as a last hope to save their lives. // Though ... study is tested on a hope to find a cure and ... ,TMC 125 is Non-nucleoside reverse transcriptase inhibitor, which has found ...
Cached Medicine News:Health News:India set to become the global knowledge hub 2Health News:India set to become the global knowledge hub 3Health News:India set to become the global knowledge hub 4
(Date:7/29/2014)... Mass., July 29, 2014 Cynosure, Inc. ... markets laser- and light-based aesthetic treatment systems for high-volume ... ended June 30, 2014. Second-quarter 2014 financial results incorporate ... on June 24, 2013. Second-Quarter ... increased 45% to $72.6 million , Non-GAAP net ...
(Date:7/29/2014)... July 29, 2014   ... will present data from a Phase I clinical ... slow or stop Parkinson,s disease progression. The Michael J. ... grant and will discuss the impact of the results ... When:   Thursday, July 31, 2014     ...
(Date:7/29/2014)... Calif. , July 29, 2014  Drug ... amplified with rising incidence rates and the intense ... a preventative vaccine. Change is underway as the ... regimens towards highly effective, easily-tolerated, interferon-free oral therapies. ... Gilead,s mega blockbuster Sovaldi is ...
Breaking Medicine Technology:Cynosure Reports Second-Quarter 2014 Financial Results 2Cynosure Reports Second-Quarter 2014 Financial Results 3Cynosure Reports Second-Quarter 2014 Financial Results 4Cynosure Reports Second-Quarter 2014 Financial Results 5Cynosure Reports Second-Quarter 2014 Financial Results 6Cynosure Reports Second-Quarter 2014 Financial Results 7Cynosure Reports Second-Quarter 2014 Financial Results 8Cynosure Reports Second-Quarter 2014 Financial Results 9Cynosure Reports Second-Quarter 2014 Financial Results 10Cynosure Reports Second-Quarter 2014 Financial Results 11Cynosure Reports Second-Quarter 2014 Financial Results 12Reminder/Media Advisory/AFFiRiS AG Presents Early Clinical Data on a First-of-its-Kind Parkinson's Disease Vaccine 2A Treatment Revolution is Underway: All-Oral Therapies Transform Global Hepatitis C Antiviral Market 2A Treatment Revolution is Underway: All-Oral Therapies Transform Global Hepatitis C Antiviral Market 3A Treatment Revolution is Underway: All-Oral Therapies Transform Global Hepatitis C Antiviral Market 4
... September 24 , - Novel Treatment ... and Reduction in Depressive Symptoms, Positive ... today at the 8th,European Congress of Epileptology, ... a novel once daily,anti-epileptic agent, significantly reduced ...
... Oral Insulin Capsule, ... on Type 1 Diabetics, JERUSALEM, Israel, September ... delivery systems, announced today that it has commenced Phase 2A,studies of ORMD ... Medical Center in Jerusalem, Israel., Oramed,s Phase 2A trial is focused ...
Cached Medicine Technology:New Data Show Efficacy of Zebinix(TM) in the Treatment of Epilepsy 2New Data Show Efficacy of Zebinix(TM) in the Treatment of Epilepsy 3New Data Show Efficacy of Zebinix(TM) in the Treatment of Epilepsy 4New Data Show Efficacy of Zebinix(TM) in the Treatment of Epilepsy 5New Data Show Efficacy of Zebinix(TM) in the Treatment of Epilepsy 6Oramed Pharmaceuticals Commences Phase 2A Trials of its Oral Insulin Capsule on Type 1 Diabetics 2
... German Craftsmanship have produced ... in the world. Ocutek ... to you! Only holders ... certificate, which requires and ...
... German Craftsmanship have produced ... in the world. Ocutek ... to you! Only holders ... certificate, which requires and ...
... are constructed of a patented ... polyvinyl acetal sponge. Each device ... to both surgeon and patient, ... firm enough to gently manipulate ...
... Merocel Ophthalmic Products provide ... fiber free products for ... safe cleaning of fine ... Merocel material is highly ...
Medicine Products: