Navigation Links
ASU leads $5 million NIH-sponsored research initiative to advance diabetes care and treatment
Date:11/1/2011

inical studies to advance the difficult search for markers that may be useful for both diagnosis and for assessing potential new drug therapies."

The study will examine and validate biomarkers in people with diabetes, some of whom will have had a heart attack. It is unlikely that a single biomarker will have enough predictive power to assess heart attack risk; rather, panels of biomarkers will be needed to identify drug targets.

"There is a great need for more-effective biomarkers of macrovascular complications of diabetes and for surrogate indicators of favorable response to potential diabetes therapies," said Peter Reaven, M.D., who will oversee the selection of target biomarkers and clinical work, including patient recruitment at the Phoenix VA Health Care System. "Our goal is to identify novel proteins and relevant protein modifications that reflect many of the critical mechanisms that underlay vascular disease in diabetes to develop a more comprehensive panel of biomarkers. One advantage to our team approach is that it will integrate, from the very beginning, the many aspects and disciplines required for a pipeline of biomarker discovery, validation and translation." Pfizer will play a key role in translating prognostic biomarkers of cardiovascular disease risk for decision-making during drug development for type 2 diabetes.

"Prognostic markers of cardiovascular disease risk have been an essential need for type 2 diabetes drug development ever since Nissen published his influential report suggesting some drugs may increase heart attack rates," said Jim Pearson, Ph.D., head of Personalized Medicine at Pfizer in Kalamazoo, MI. "The FDA now requires patients with a higher risk for cardiovascular events to be enrolled in Phase III clinical trials for two years instead of three-to-six months. The problem is that a useful directed proteomics CVD risk panel has yet to be translated. A biomarker panel that is more comprehensive than HbA1c
'/>"/>

Contact: Joe Caspermeyer
joseph.caspermeyer@asu.edu
480-727-0369
Arizona State University
Source:Eurekalert  

Page: 1 2 3

Related medicine news :

1. Rise in Vulvar Precancers Leads to New Guidelines
2. Project leads next decade of aging research across Europe
3. Project leads next decade of ageing research across Europe
4. X-ray protein probe leads to potential anticancer tactic
5. Insulation from public pressure leads to more accurate suicide reporting by death investigators
6. Unconventional hunt for new cancer targets leads to a powerful drug candidate for leukemia
7. Stronger social safety net leads to decrease in stress, childhood obesity
8. Drug improves brain function in condition that leads to Alzheimers
9. Drinking until you forget leads to injuries for college kids
10. 2 talks with teens leads to less marijuana use for at least a year
11. FSU scientist leads research on AIDS-related cancer
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
ASU leads $5 million NIH-sponsored research initiative to advance diabetes care and treatment
(Date:9/1/2014)... September 02, 2014 NAPW ... Healthcare, LLC as a 2014 Professional Woman of the ... for leadership in office management. As the largest, most-recognized ... virtually every industry and profession, the National Association of ... over 600,000 members and nearly 300 Local Chapters. , ...
(Date:9/1/2014)... NAPW honors ... Orthopedics Pain Treatment & Cardiology, as a ... is recognized with this prestigious distinction for leadership ... organization of women in the country, spanning virtually ... Professional Women is a powerfully vibrant networking community ...
(Date:9/1/2014)... (PRWEB) September 02, 2014 Spine Team ... annual Reader’s Choice ‘Best of 2014’ award based on ... Northeast Tarrant County, Las Colinas & Coppell, Rockwall & ... would like to thank our patients and the residents ... Texas as LIVING magazine’s ‘Best of 2014’ in the ...
(Date:9/1/2014)... an innovative Washington State University study of deadly force ... black people. But when it came time to shoot, ... longer to pull the trigger against them than against ... the recent Journal of Experimental Criminology , grow ... disproportionate number of ethnic and racial minorities shot by ...
(Date:9/1/2014)... UWDress.com, a well-known wedding dress manufacturer and ... green bridesmaid dresses for its new and old ... company’s online category. What’s more, they are offered at ... offer is specially launched to celebrate the coming of ... have won great appreciation from worldwide clients. Now, the ...
Breaking Medicine News(10 mins):Health News:National Association of Professional Women Announces Victoria Smith, Office Manager at Apex Healthcare, LLC, a 2014 Professional Woman of the Year 2Health News:National Association of Professional Women Announces Laura Brinkley, Manager, Gibson Orthopedics Pain Treatment & Cardiology Clinic, a 2014 Professional Woman of the Year 2Health News:Spine Team Texas chosen in LIVING Magazine’s Reader’s Choice Awards 2Health News:WSU 'deadly force' lab finds racial disparities in shootings 2Health News:WSU 'deadly force' lab finds racial disparities in shootings 3Health News:2014 Lime Green Bridesmaid Dresses Offered At UWDress.com 2
... could help keep ones mind working.The study also found those ... fat have an increased risk of cognitive impairment during middle ... eat could play a role in your risk for dementia. ... with a lower risk of dementia. Researchers in the Netherlands ...
... in the recent issue of British Medical Journal say ... suicides and suicidal attempts.// ,Depression is characterized ... activities, low levels of self-esteem and confidence, and in ... and suicide. ,Clinical depression, also known as ...
... thyroid problem may have a lower risk of developing ... have shown that one of the circulating thyroid hormones ... mammary gland cells responded to thyroid hormones , population ... thyroid hormone and breast cancer. ,In a recent ...
... recent study researchers suggest that women drink wine to keep their ... wine is good for the heart. Although much of the research ... men, it is still not clear why moderate amounts of wine ... effects of wine on women’s hearts, the alcohol habits of 102 ...
... research conducted by Northwestern University about the effects of epidural ... analgesic given at the early stages of labor does not ... in their final term were observed for the study. All ... women who were given epidural in the early stages of ...
... onset wheezing is associated with high levels of allergies, ... the longest duration of wheezing also appear to have ... later in childhood end up with the same characteristics ... involved nearly 1,500 children born on the Isle of ...
Cached Medicine News:
(Date:8/29/2014)... , Aug. 29, 2014 Medina Medical announced ... and member of the Board of Directors on August ... device development and commercialization experience, including over a decade ... previously served as a Partner of the medical device ... CEO of two Foundry start-ups. Mr. Engelson previously served ...
(Date:8/29/2014)... 2014 Research and Markets has ... Therapeutics Market & Pipeline Insight 2014" report to ... to prevent and eradicate the prevalence of cancer have ... confined to low specificity, safety and large number of ... a better solution. It has been discovered that peptides ...
(Date:8/29/2014)... , Aug. 29, 2014 Research ... "Research and Development Trend Forecast of Pharmaceutical Equipment ... Research and Development Trend Forecast of ... 2014-2018 mainly analyzes China,s pharmaceutical ... supply & demand, competition landscape, and business performance of ...
Breaking Medicine Technology:Medina Medical Announces Erik T. Engelson Joins as Chief Executive Officer 2Global Peptide Cancer Therapeutics Market & Pipeline Insight 2014 2Research and Development Trend Forecast of Pharmaceutical Equipment Market in China, 2014-2018 2
... UBM Live today announced details of the ... pharmaceutical contract services and outsourcing. ICSE, hosted from June ... the most international pharmaceutical events line-up in China, which ... pharma machinery and equipment, BioPh China for the biopharmaceuticals ...
... Stereotaxis, Inc. (NASDAQ: STXS ) today ... 31, 2011.  First quarter results included continued strong momentum ... Odyssey™ systems and growth in recurring revenue.  In addition, ... which enhances the efficiency and versatility of the Niobe ...
Cached Medicine Technology:ICSE China to Offer Inaugural Conference Programme in 2011 2ICSE China to Offer Inaugural Conference Programme in 2011 3Stereotaxis Reports First Quarter 2011 Financial Results 2Stereotaxis Reports First Quarter 2011 Financial Results 3Stereotaxis Reports First Quarter 2011 Financial Results 4Stereotaxis Reports First Quarter 2011 Financial Results 5Stereotaxis Reports First Quarter 2011 Financial Results 6Stereotaxis Reports First Quarter 2011 Financial Results 7
... ARUP Laboratories is a national reference laboratory ... research and development. ARUP offers an extensive ... medical tests in clinical and anatomic pathology. ... Laboratories' clients include more than half of ...
... Laboratories is a national reference laboratory and ... and development. ARUP offers an extensive test ... tests in clinical and anatomic pathology. Owned ... clients include more than half of the ...
... reference laboratory and a worldwide leader in ... an extensive test menu of highly complex ... anatomic pathology. Owned by the University of ... half of the nation's university teaching hospitals ...
... Laboratories is a national reference laboratory and ... and development. ARUP offers an extensive test ... tests in clinical and anatomic pathology. Owned ... clients include more than half of the ...
Medicine Products: