Navigation Links
ASU leads $5 million NIH-sponsored research initiative to advance diabetes care and treatment
Date:11/1/2011

inical studies to advance the difficult search for markers that may be useful for both diagnosis and for assessing potential new drug therapies."

The study will examine and validate biomarkers in people with diabetes, some of whom will have had a heart attack. It is unlikely that a single biomarker will have enough predictive power to assess heart attack risk; rather, panels of biomarkers will be needed to identify drug targets.

"There is a great need for more-effective biomarkers of macrovascular complications of diabetes and for surrogate indicators of favorable response to potential diabetes therapies," said Peter Reaven, M.D., who will oversee the selection of target biomarkers and clinical work, including patient recruitment at the Phoenix VA Health Care System. "Our goal is to identify novel proteins and relevant protein modifications that reflect many of the critical mechanisms that underlay vascular disease in diabetes to develop a more comprehensive panel of biomarkers. One advantage to our team approach is that it will integrate, from the very beginning, the many aspects and disciplines required for a pipeline of biomarker discovery, validation and translation." Pfizer will play a key role in translating prognostic biomarkers of cardiovascular disease risk for decision-making during drug development for type 2 diabetes.

"Prognostic markers of cardiovascular disease risk have been an essential need for type 2 diabetes drug development ever since Nissen published his influential report suggesting some drugs may increase heart attack rates," said Jim Pearson, Ph.D., head of Personalized Medicine at Pfizer in Kalamazoo, MI. "The FDA now requires patients with a higher risk for cardiovascular events to be enrolled in Phase III clinical trials for two years instead of three-to-six months. The problem is that a useful directed proteomics CVD risk panel has yet to be translated. A biomarker panel that is more comprehensive than HbA1c
'/>"/>

Contact: Joe Caspermeyer
joseph.caspermeyer@asu.edu
480-727-0369
Arizona State University
Source:Eurekalert  

Page: 1 2 3

Related medicine news :

1. Rise in Vulvar Precancers Leads to New Guidelines
2. Project leads next decade of aging research across Europe
3. Project leads next decade of ageing research across Europe
4. X-ray protein probe leads to potential anticancer tactic
5. Insulation from public pressure leads to more accurate suicide reporting by death investigators
6. Unconventional hunt for new cancer targets leads to a powerful drug candidate for leukemia
7. Stronger social safety net leads to decrease in stress, childhood obesity
8. Drug improves brain function in condition that leads to Alzheimers
9. Drinking until you forget leads to injuries for college kids
10. 2 talks with teens leads to less marijuana use for at least a year
11. FSU scientist leads research on AIDS-related cancer
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
ASU leads $5 million NIH-sponsored research initiative to advance diabetes care and treatment
(Date:12/21/2014)... 21, 2014 AlignLife of Norton ... while at the same time helping people get their health ... community-based organization committed to serving those persons in Muskegon County ... to improve the quality of life. Dr. Michael Rykse wanted ... in the local community and he knew he found that ...
(Date:12/21/2014)... 2014 Parker & Sons, Inc. a ... plumbing and other similar home contractor services announces a ... to its expert contracting services. The company is considered ... been serving Arizona for well over 40 years. Parker ... best in quality customer service to the residents and ...
(Date:12/21/2014)... 2014 SCI explores disability ... and systemic barriers for disabled athletes with Aaron ... has a condition called juvenile macular degeneration, where he ... he adapted his athletic ambitions to his vision and ... triathlon to pioneer the way for other blind and ...
(Date:12/21/2014)... 21, 2014 As testosterone therapy ... attacks, stroke and blood clots from using testosterone products ... new study shows that the male hormone testosterone may ... a study published in the Proceedings of the National ... examined a group of male rats with naturally occurring ...
(Date:12/21/2014)... The Oncology Institute of Hope and Innovation hosted their ... offices. The Hope for the Holidays Toy Drive is a ... families during the holiday season. This year, the toy drive ... both offices. This event continues to be successful year after ... store managers and assistant managers came out and not only ...
Breaking Medicine News(10 mins):Health News:AlignLife of Norton Shores Makes a Brighter Christmas for Kids in Muskegon 2Health News:Parker & Sons Announces Record Number Of Favorable Reviews In 2014 With Regard To Its Expert Contracting Services 2Health News:Parker & Sons Announces Record Number Of Favorable Reviews In 2014 With Regard To Its Expert Contracting Services 3Health News:Disability in Sports on SCI TV with Triathlon World Champ Aaron Scheidies 2Health News:Disability in Sports on SCI TV with Triathlon World Champ Aaron Scheidies 3Health News:New Low Testosterone Therapy Study Shows Male Hormone Testosterone May Contribute To Colon Cancer Reports Wright & Schulte LLC 2Health News:New Low Testosterone Therapy Study Shows Male Hormone Testosterone May Contribute To Colon Cancer Reports Wright & Schulte LLC 3Health News:New Low Testosterone Therapy Study Shows Male Hormone Testosterone May Contribute To Colon Cancer Reports Wright & Schulte LLC 4
... RESTON, Va.A new study published in the July issue ... that positron emission tomography (PET) scans in mice can ... breast cancer treatment is working as intended. Researchers successfully ... HER2a protein often associated with aggressive breast cancerin breast ...
... and MYRTLE BEACH, S.C., July 2 Allscripts ... Omega Medical Solutions, a Myrtle Beach, SC-based medical ... Management and Allscripts Payerpath(TM) claims management solution for ... the surrounding states. , , (Logo: ...
... ... challenges for today,s modern woman. Having the right type of support, knowledge, and tools are ... pump technology for working women in decades. The Freemie system is a hands-free and concealable ... , ...
... On Thursday June 18th, 2009, the Association of Organ ... with the 2009 Excellence in Leadership Award. The AOPO ... The national award is presented to an individual who demonstrates ... , Dr. Dan Lebovitz has been actively involved in ...
... ... ... Morehead , the human capital research firm, will host a webinar titled "Preventing ... will be broadcast on Tuesday, July 14, 2009 at 1:00 p.m. EST. , ...
... tobacco tax will increase by $1.00, the biggest of its kind ... part of the Protecting Florida,s Health Act. The pressures of a ... and quit spontaneously. , , New data published in the ... quit attempts are unplanned and these types of attempts can be ...
Cached Medicine News:Health News:Study shows PET can measure effectiveness of novel breast cancer treatment 2Health News:Omega Medical Solutions Selects Allscripts Practice Management and Allscripts Payerpath Revenue Cycle Management 2Health News:Omega Medical Solutions Selects Allscripts Practice Management and Allscripts Payerpath Revenue Cycle Management 3Health News:Omega Medical Solutions Selects Allscripts Practice Management and Allscripts Payerpath Revenue Cycle Management 4Health News:Omega Medical Solutions Selects Allscripts Practice Management and Allscripts Payerpath Revenue Cycle Management 5Health News:Working Moms Find Freedom to Use Breast Pumps Where They Want, When They Want 2Health News:Dr. Dan Lebovitz of Ohio Receives Leadership Award 2Health News:Morehead Presents Webinar on Preventing Physician Disloyalty: Building Stability and Trust with 'At-Risk' Physicians 2Health News:Florida State Tobacco Tax Increase May Prompt Smokers to Quit Spontaneously 2Health News:Florida State Tobacco Tax Increase May Prompt Smokers to Quit Spontaneously 3
(Date:12/17/2014)... , Dec. 17, 2014 Royal Philips ... (NASDAQ: VOLC ), a global leader in catheter-based ... they have entered into a definitive merger agreement. Pursuant to ... all of the issued and outstanding shares of Volcano for ... of USD 1 billion (approx. EUR 800 million), to be ...
(Date:12/17/2014)... , Dec. 17, 2014 With advancements ... the MRI market is seeing new growth, according ... MRI scans account for the majority of market ... resolution of images, which are creating opportunities for more ... market is growing at a rate of 4%, ...
(Date:12/17/2014)... 17, 2014  RXi Pharmaceuticals Corporation (NASDAQ: ... discovering, developing and commercializing innovative therapies addressing major ... of enrollment in its first Phase 2a study, ... confirmed the 1-month findings that were reported in ... - http://photos.prnewswire.com/prnh/20130917/NE80755LOGO , , ...
Breaking Medicine Technology:Philips to acquire Volcano to expand global leadership position in image-guided therapy market 2Philips to acquire Volcano to expand global leadership position in image-guided therapy market 3Philips to acquire Volcano to expand global leadership position in image-guided therapy market 4Philips to acquire Volcano to expand global leadership position in image-guided therapy market 5Philips to acquire Volcano to expand global leadership position in image-guided therapy market 6Philips to acquire Volcano to expand global leadership position in image-guided therapy market 7Philips to acquire Volcano to expand global leadership position in image-guided therapy market 8Kalorama: 3T Advancements Bringing New Growth to the MRI Market 2Kalorama: 3T Advancements Bringing New Growth to the MRI Market 3RXi Pharmaceuticals Announces Sustained Effect of RXI-109 at Three Months Post Scar Revision Surgery and the Completion of Enrollment for its Phase 2a Trial RXI-109-1301 2RXi Pharmaceuticals Announces Sustained Effect of RXI-109 at Three Months Post Scar Revision Surgery and the Completion of Enrollment for its Phase 2a Trial RXI-109-1301 3RXi Pharmaceuticals Announces Sustained Effect of RXI-109 at Three Months Post Scar Revision Surgery and the Completion of Enrollment for its Phase 2a Trial RXI-109-1301 4RXi Pharmaceuticals Announces Sustained Effect of RXI-109 at Three Months Post Scar Revision Surgery and the Completion of Enrollment for its Phase 2a Trial RXI-109-1301 5
... Boehringer Ingelheim Pharmaceuticals, Inc. announced that new data ... 1 trial show that afatinib (BIBW 2992) reached a ... in progression-free survival (PFS) in advanced non-small cell lung ... growth factor receptor (EGFR) mutation.(1)  The updated LUX-Lung 1 ...
... Clarient, Inc. (Nasdaq: CLRT ), a ... the pharmaceutical industry, today announced the commercial launch of ... the likelihood of recurrence of breast cancer following surgery ... an optimal set of five biomarkers that are able ...
Cached Medicine Technology:New Subgroup Analysis of LUX-Lung 1 Trial Suggests Afatinib Increases Progression-Free Survival in Advanced Lung Cancer Patients More Likely to Have EGFR Mutations 2New Subgroup Analysis of LUX-Lung 1 Trial Suggests Afatinib Increases Progression-Free Survival in Advanced Lung Cancer Patients More Likely to Have EGFR Mutations 3New Subgroup Analysis of LUX-Lung 1 Trial Suggests Afatinib Increases Progression-Free Survival in Advanced Lung Cancer Patients More Likely to Have EGFR Mutations 4New Subgroup Analysis of LUX-Lung 1 Trial Suggests Afatinib Increases Progression-Free Survival in Advanced Lung Cancer Patients More Likely to Have EGFR Mutations 5Clarient Launches Insight® Dx Mammostrat® Breast Cancer Recurrence Test 2Clarient Launches Insight® Dx Mammostrat® Breast Cancer Recurrence Test 3Clarient Launches Insight® Dx Mammostrat® Breast Cancer Recurrence Test 4
... comprehensive line of pregnancy tests including rapid ... convenient one-step stick and cassette formats. The ... Easy HCG is a 25 mIU urine ... HCG II provides 25mIU sensitivity for ...
For the quantitative determination of Glycohemoglobin (HbA1) in blood by,cation exchange resin. The test is to be used to monitor long-term glucose,control in diabetes mellitus....
... isotopic anemia assays feature ... ,pipetting steps for greater ... the processes ,involved in ... benefit to your laboratory ...
... Bio-Rad isotopic anemia ... and minimal ,pipetting steps ... information about the processes ... and the benefit to ...
Medicine Products: