Navigation Links
11 new genetic susceptibility factors for AD discovered through the largest study
Date:10/27/2013

of the nation's researchers working on the genetics of AD as well as many investigators and resources of the 29 NIA funded Alzheimer Disease Centers.

"This study clearly demonstrates that there really is strength in numbers to identify genes that individually have a small effect on risk of Alzheimer's," said Farrer. "But it's not the magnitude of the odds ratio that's really important. Each gene we implicate in the disease process adds new knowledge to our understanding of disease mechanism and provides insight into developing new therapeutic approaches, and ultimately these approaches may be more effective in halting the disease since genes are expressed long before clinical symptoms appear and brain damage occurs," he added.

"This landmark international effort has uncovered new pathways and new genes in old pathways that are definitely associated with Alzheimer dementia, but we need to do much work to better understand how exactly these genes work in health and disease, and to perhaps make drugs from these genes and molecules," said Seshadri. "We will continue to mine these results for new insights, even as we include more patients and use new technologies like whole genome sequencing to find more new pathways and genes," she added.

"Alzheimer's is a complex and devastating disorder, and if we are to reach our goal of finding effective therapies to treat it, then collaboration is key," said Neil Buckholtz, PhD, NIA Division of Neuroscience Director. "IGAP's sharing of DNA samples, data sets and scientific insights proves that team concept, and NIA is gratified to have provided the infrastructure and support needed to move the team forward."


'/>"/>

Contact: Gina DiGravio
gina.digravio@bmc.org
617-638-8480
Boston University Medical Center
Source:Eurekalert

Page: 1 2 3

Related medicine news :

1. IntegraGen launches ARISk test, a genetic screening tool for autism in high-risk children
2. 2 genetic deletions in human genome linked to the development of aggressive prostate cancer
3. Head, Body Lice Are Genetically Very Similar
4. Certain Genetic Regions May Be Tied to Osteoporosis
5. Study of half siblings provides genetic clues to autism
6. Genetic variants, tobacco exposure and lung cancer risk
7. Research Gets Closer to Genetic Roots of Glaucoma
8. Moffitt researcher awarded GE grant to develop tool to detect breast cancer metastasis genetic risks
9. Genetically modified T cell therapy shown to be safe, lasting in decade-long study of HIV patients
10. Some women may be genetically predisposed to smoking-related hot flashes
11. Genetic abnormalities in benign or malignant tissues predict relapse of prostate cancer
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/24/2014)... The U.S. Food & Drug ... Entertainment Industries Council (EIC) have teamed with entertainment ... Story on a first-of-its-kind Decorative Contact Lens ... illegal and unsafe lens use to the forefront. ... tens-of-thousands, is now releasing its second production which ...
(Date:7/24/2014)... -- Some babies are at risk for autism because they ... find new ways to detect Autism Spectrum Disorder (ASD) earlier ... with others and how they relate to the possibility and ... to understand the connection between early joint attention before one ... form of communication that develops toward the end of the ...
(Date:7/24/2014)... Skirt Sports, the innovative women’s running apparel brand is proud ... from an idea by professional triathlete Nicole DeBoom during a ... this one innovative piece of running gear revolutionized the fitness ... in Wisconsin to incorporate Skirt Sports, the first company to ... I drew the first sketch of a running skirt on ...
(Date:7/24/2014)... July 24, 2014 The report, “Feed ... Synthetic), by Livestock (Swine, Poultry, Cattle, Pets, Aquaculture, and ... and segments the feed palatability enhancers & modifiers market ... in terms of value, of types of feed flavors, ... tables and 17 figures spread through 275 pages and ...
(Date:7/24/2014)... County high school students are smoking tobacco products at ... to new data from the Prevention Research Center for ... 2013, more than 22 percent, or one in five ... within the prior 30 days. , Equally surprising is ... hookahs, or water pipes, more than cigarettes matching ...
Breaking Medicine News(10 mins):Health News:Optometric Professionals Team with Hollywood for Second Installment of Video Campaign 2Health News:Optometric Professionals Team with Hollywood for Second Installment of Video Campaign 3Health News:Optometric Professionals Team with Hollywood for Second Installment of Video Campaign 4Health News:Early warning sign for babies at risk of autism 2Health News:Skirt Sports Celebrates Its 10-Year Anniversary and 10 Years of the Running Skirt With a Virtual Community Building Run 2Health News:Skirt Sports Celebrates Its 10-Year Anniversary and 10 Years of the Running Skirt With a Virtual Community Building Run 3Health News:Feed Palatability Enhancers & Modifiers Market Worth $3172.6 Million by 2019 - Report by MarketsandMarkets 2Health News:Feed Palatability Enhancers & Modifiers Market Worth $3172.6 Million by 2019 - Report by MarketsandMarkets 3Health News:Feed Palatability Enhancers & Modifiers Market Worth $3172.6 Million by 2019 - Report by MarketsandMarkets 4Health News:Cuyahoga County high school students smoking at the same rate as adults 2Health News:Cuyahoga County high school students smoking at the same rate as adults 3Health News:Cuyahoga County high school students smoking at the same rate as adults 4
... PALO ALTO, Calif., Feb. 1 Lifespring Health,sponsors the ... Run.,This is an important charity event benefiting the Hemophilia ... Disabilities and,the Koret Family House., Set to take ... Marathon,Championship certified 13.1 mile course is ranked as one ...
... non-REM sleep (45 minutes) obtained during a daytime nap clearly ... published in the February 1 issue of the journal SLEEP. ... the Center for Sleep and Cognition and the department of ... males, 22 females) with an average age of 23.3 years. ...
... North Carolina researchers have found that women with irritable bowel ... have a heightened brain response to pain that makes them ... affects 10 to 15 percent of the population and causes ... , Researchers used brain imaging to show that patients ...
... Business Leaders Learn How Their Employee Health Benefit ... Business owners and human,resource executives grappling with ... and cost effective found out how their plans,compare ... Embassy Suites,Parsippany. Scott Rappoport, a 25-year veteran of ...
... Gastric Band Surgery Performed Each Month in ... LONDON, February 1 Today saw the launch ... information and support to people considering obesity surgery. To,coincide ... new survey reveal,widespread confusion over the causes of obesity ...
... getting preventive treatments , , THURSDAY, Jan. 31 (HealthDay ... hospitals worldwide risk developing dangerous blood clots known ... that could prevent the condition, a large international ... recognized to be one of the most common ...
Cached Medicine News:Health News:Journal Sleep: Study concludes a daytime nap can benefit a person's memory performance 2Health News:Key to Attracting and Retaining Quality Employees: Benefits 2Health News:Key to Attracting and Retaining Quality Employees: Benefits 3Health News:Lose Weight Gain Life: New Website to Help People Seeking Information on Obesity Surgery 2Health News:Lose Weight Gain Life: New Website to Help People Seeking Information on Obesity Surgery 3Health News:Hospital Patients' Blood Clot Risk High 2Health News:Hospital Patients' Blood Clot Risk High 3
(Date:7/24/2014)... -- Delivery of the Report will take 2-3 ... Photo - http://photos.prnewswire.com/prnh/20140723/129707 ... on Global and Chinese Hemodialysis Machine industry. The ... Machine including its classification, application and manufacturing technology. ... manufacturers of Hemodialysis Machine listing their product specification, ...
(Date:7/24/2014)... 24, 2014 Cancer patients in the west of ... cancer treatment closer to home when a new radiotherapy center ... Medical Systems (NYSE: VAR ) has been selected ... in June for four TrueBeam™ medical linear accelerators. ... and efficient radiotherapy and radiosurgery treatments, will replace older treatment ...
(Date:7/24/2014)...  Blueprint Medicines (Blueprint), a leader in discovering highly ... announced the appointment of Jeffrey Albers as ... Algeta ASA, where he served on the executive management ... Bayer. Mr. Albers succeeds Alexis Borisy , co-founder ... Rock Ventures, who will remain an active member of ...
Breaking Medicine Technology:Hemodialysis Machine Industry for Global and Chinese Markets Forecast to 2019 2Hemodialysis Machine Industry for Global and Chinese Markets Forecast to 2019 3Hemodialysis Machine Industry for Global and Chinese Markets Forecast to 2019 4Hemodialysis Machine Industry for Global and Chinese Markets Forecast to 2019 5Varian Medical Systems Selected to Equip First Satellite Radiotherapy Center in Scotland 2Varian Medical Systems Selected to Equip First Satellite Radiotherapy Center in Scotland 3Blueprint Medicines Appoints Jeffrey Albers as Chief Executive Officer 2
... Nov. 14, 2011 Tengion, Inc. (Nasdaq: ... of a restructuring plan, and reported its financial results ... restructuring plan is designed to fund the Company,s lead ... the Company,s anticipated cash utilization.  As a result of ...
... Texas, Nov. 14, 2011 Novation commends the IMS ... raising awareness of the drug shortage crisis facing America,s ... Look at Products, Suppliers and Volume Volatility."   ... 2011 Executive Order, is helping bring much-needed attention to ...
Cached Medicine Technology:Tengion Provides Business Update and Reports Third Quarter 2011 Financial Results 2Tengion Provides Business Update and Reports Third Quarter 2011 Financial Results 3Tengion Provides Business Update and Reports Third Quarter 2011 Financial Results 4Tengion Provides Business Update and Reports Third Quarter 2011 Financial Results 5Tengion Provides Business Update and Reports Third Quarter 2011 Financial Results 6Tengion Provides Business Update and Reports Third Quarter 2011 Financial Results 7Tengion Provides Business Update and Reports Third Quarter 2011 Financial Results 8Tengion Provides Business Update and Reports Third Quarter 2011 Financial Results 9Tengion Provides Business Update and Reports Third Quarter 2011 Financial Results 10Novation Applauds the IMS Institute for Healthcare Informatics for Calling Attention to the Drug Shortage Crisis Facing American Hospitals 2Novation Applauds the IMS Institute for Healthcare Informatics for Calling Attention to the Drug Shortage Crisis Facing American Hospitals 3
The Surgiflex WAVE XP couples the state-of-the-art Surgiflex WAVE Probe with the convenience of a truly portable battery-powered pump....
Stryker Endoscopy has combined a standardized pressurizing system with an advanced hand piece design that is lightweight and compact in order to streamline laparoscopic procedures....
... specifically to disintegrate renal and ... state-of-the-art technology in a compact ... efficient and affordable lithotripsy system. ... level of clinical results for ...
...
Medicine Products: