The European Prospective Investigation into Cancer and Nutrition (EPIC) study is a Europe-wide prospective cohort study of the relationships between diet and cancer, as well as other chronic diseases, such as cardiovascular disease. With over half a million participants, it is the largest study of diet and disease to be undertaken.
EPIC is coordinated by the International Agency for Research on Cancer (IARC), part of the World Health Organization, and funded by the 'Europe Against Cancer' programme of the European Commission as well as multiple nation-specific grants and charities.
521,457 healthy adults, mostly aged 35-70 years, were enrolled in 23 centres in ten European countries: Denmark (11%), France (14%), Germany (10%), Greece (5%), Italy (9%), The Netherlands (8%), Norway (7%), Spain (8%), Sweden (10%) and the United Kingdom (17%). One UK centre (Oxford) recruited 27,000 vegetarians and vegans; this subgroup forms the largest study of this dietary group. Recruitment to the study took place between 1993 and 1999, and follow up is planned for at least ten years, with repeat interview/questionnaires every three to five years. The main prospective data collected are standardised dietary questionnaires (self administered or interview based), seven-day food diaries, blood samples and anthropometric measurements, such as body mass index and waist-to-hip ratio. Additionally, the GenAir case-control study is studying the relationship of passive smoking and air pollution with cancers and respiratory diseases.
Up to 2004, there were over 26,000 new cases of cancer recorded among participants, with the most common being cancers of the breast, colorectum, prostate and lung. Current analyses are focusing particularly on stomach, colorectal, breast, prostate and lung cancers. The different dietary patterns in the different countries should enable reliable associations to be made between particular diets and cancers. The analysis of stored blood samples should also allow dissection of genetic factors involved in cancers, as well as the effects of hormones and hormone-like factors.
- Consumption of fibre, fish, milk and cheese reduce risk of colorectal cancer, while red and processed meat increase risk
- Consumption of fruit and vegetables does not affect risk of breast or prostate cancer
- Bingham SA, Day NE, Luben R, et al. Dietary fibre in food and protection against colorectal cancer in the European Prospective Investigation into Cancer and Nutrition (EPIC): an observational study. Lancet (2003) 361: 1496-1501 PubMed
- Gonzalez CA, Jakszyn P, Pera G, et al. Meat intake and risk of stomach and esophageal adenocarcinoma within the European Prospective Investigation Into Cancer and Nutrition (EPIC). J. Natl Cancer Inst. (2006) 98: 345-354
- Khaw KT, Bingham S, Welch A, et al. Relation between plasma ascorbic acid and mortality in men and women in EPIC-Norfolk prospective study: a prospective population study. European Prospective Investigation into Cancer and Nutrition. Lancet (2001) 357: 657-663 PubMed
- Miller AB, Altenburg HP, Bueno-de-Mesquita B, et al. Fruits and vegetables and lung cancer: Findings from the European Prospective Investigation into Cancer and Nutrition. Int. J. Cancer (2004) 108: 269-276 PubMed
- Norat T, Bingham S, Ferrari P, et al. Meat, fish, and colorectal cancer risk: the European Prospective Investigation into cancer and nutrition. J. Natl Cancer Inst. (2005) 97: 906-916
(Date:3/5/2014)... to nicotine could manifest as attention deficit hyperactivity disorder ... new study by Florida State University College of Medicine ... have found evidence that ADHD associated with nicotine can ... ADHD might be an environmentally induced health condition inherited ... pregnancy a long time ago. And the fact that ...
(Date:3/5/2014)... UNC,s Frank Porter Graham Child Development Institute (FPG) and ... life after high school. , "Public high schools may ... with autismand for their families," said FPG director Samuel ... and few social ties after school ends." , According ... work hard to achieve beneficial results for students with ...
(Date:3/5/2014)... It may seem normal: As we age, we misplace ... learned or a meal we just ordered. But University ... be inevitable, and they,ve found a drug therapy that ... The drug can,t yet be used in humans, but ... the population of aging adults who don,t have Alzheimer,s ...
(Date:3/5/2014)... immunotherapy strategies designed to induce the immune ... a new and cost-effective weapon against some of ... mesothelioma. Investigators from the Massachusetts General Hospital (MGH) ... Journal of Hematology & Oncology that a ... tumor-cell-surface antigen with another protein that stimulates several ...
(Date:3/4/2014)... drug aimed at restoring the immune system,s ability ... or shrank tumors in patients with advanced melanoma, ... Johns Hopkins Kimmel Cancer Center and 11 other ... prior systemic therapies, and most had received two ... responses to the drug, nivolumab (anti-PD-1; BMS-936558; MDX-1106; ... Breaking Medicine News(10 mins):Health News:Prenatal nicotine exposure may lead to ADHD in future generations 2Health News:Prenatal nicotine exposure may lead to ADHD in future generations 3Health News:New program for students with autism offers hope after high school 2Health News:UF researchers find drug therapy that could eventually reverse memory decline in seniors 2Health News:Novel cancer vaccine holds promise against ovarian cancer, mesothelioma 2Health News:Novel cancer vaccine holds promise against ovarian cancer, mesothelioma 3Health News:Investigational drug may increase survival for some patients with advanced melanoma 2
Other medicine definitionOther Tags
... New Report Details the Structure and Funding Of U.S. ... With attention to global health rising on the ... Foundation today launched a set of new resources providing ... the global health arena with timely information, including daily ...
... Value Is Through A Sale to A Strategic Acquirer.RALEIGH, ... stockholder of BioScrip, Inc. (Nasdaq: BIOS ), ... the Board of Directors of BioScrip in which Anchor ... through simultaneous i) cost rationalizations and ii) exploration of ...
... N.C., April 27 Susan Brady of ... professionals in the nation to become certified by ... nonprofit organization that provides advocacy and education for ... demonstrated in-depth knowledge and expertise on best practices ...
... Monitoring Companies Demonstrates FORA Technology at Telemedicine Conference in ... Fora Care and Fora Care Suisse AG (Fora Care,s ... innovative telemedicine program at the American Telemedicine Association (ATA) ... Casino in Las Vegas, Nev. The veteran telemedicine ...
... Daily exposure to toxins in the products we ... insecticides, are creating a toxic load on our bodies ... In light of increased awareness of our environmental exposures, ... ) announced today the release of three new testing ...
... to 10-minute soaks, twice a week, prevent painful flare-ups, ... Diluted bleach baths offer a safe, simple and inexpensive ... researchers. , The skin disease, which affects 17 percent ... their ability to concentrate in school. , Eczema-related ...Cached Medicine News:Health News:Kaiser Family Foundation Launches Daily Global Health Policy Report and Policy Tracking Tool As Part of New Web Gateway Focusing on U.S. Global Health Policy 2Health News:Kaiser Family Foundation Launches Daily Global Health Policy Report and Policy Tracking Tool As Part of New Web Gateway Focusing on U.S. Global Health Policy 3Health News:Anchor Capital Calls on BioScrip Board to Pursue Cost Reductions While Exploring Strategic Sale to Unlock Shareholder Value 2Health News:Anchor Capital Calls on BioScrip Board to Pursue Cost Reductions While Exploring Strategic Sale to Unlock Shareholder Value 3Health News:Anchor Capital Calls on BioScrip Board to Pursue Cost Reductions While Exploring Strategic Sale to Unlock Shareholder Value 4Health News:Anchor Capital Calls on BioScrip Board to Pursue Cost Reductions While Exploring Strategic Sale to Unlock Shareholder Value 5Health News:Anchor Capital Calls on BioScrip Board to Pursue Cost Reductions While Exploring Strategic Sale to Unlock Shareholder Value 6Health News:Anchor Capital Calls on BioScrip Board to Pursue Cost Reductions While Exploring Strategic Sale to Unlock Shareholder Value 7Health News:MedThink Communications Account Director Among First to Receive CMPP Certification in Medical Publications Planning and Development 2Health News:Fora Care and Fora Care Suisse AG Launch Diabetes Telehealth Solution at ATA 2Health News:Fora Care and Fora Care Suisse AG Launch Diabetes Telehealth Solution at ATA 3Health News:Metametrix Announces New Toxic Effects Profiles to Help Combat Growing Concerns About Toxicity and Health 2Health News:Diluted Bleach Baths Ease Kids' Eczema 2