Navigation Links
Artecoll


Artecoll, used in cosmetic plastic surgery as permanent soft tissue filler, is injected under the skin to plump up wrinkles and reduce folds of skin associated with aging such as the nasolabial fold which runs from the corner of the nose to the edges of the mouth. Now produced for Americans in San Diego, California, by Artes Medical, Inc, Artecoll has been used in Europe for many years. It was approved by the U.S. FDA in December, 2006, to treat nasolabial folds with the added condition that a five-year follow up study of patients using Artecoll must be done.

Contents

Composition

Artecoll is mostly collagen, one of the most abundant substances in all mammals. The thinning of collagen in human faces is responsible for aging, wrinkles and lines on the face.[1]

Artecoll consists of 25 percent microscopic Plexiglas plastic beads made of a substance known as polymethylmethacrylate suspended in a solution of 75 percent bovine collagen. The microspheres are 32–40 micrometers in diameter (500 micrometers could fit in the period at the end of this sentence).

Potential risks and side effects

Some researchers have found that large lumps under the skin known as granulomas developed after Artecoll injections. The lumps are a reaction to the injections and can be difficult for doctors to treat.[2]

U.S. Food and Drug Administration approval

Before Artecoll was approved by the U.S. FDA, it was studied in 251 subjects at eight medical centers in the United States. The subjects received Artecoll injections in 1334 wrinkles of the glabella, the heavy wrinkles between the eyebrows, in the corner-of-the-mouth lines, in upper lips and in the nasolabial folds. A similar group of patients received injections of ordinary collagen (with the trade name Zyplast™) in the same places in their faces.

Researchers then studied the patients' improved appearance and the reactions of research subjects to the injections. At the six-month follow up, the researchers found the Artecoll group showed 86.7 percent better augmentation of loose skin than the group which received only collagen. Adverse reactions to collagen and to Artecoll among both groups of patients was reported as about equal.[3]

References

  1. ^ Cohen SR, Homes RE. Artecoll: A long-lasting injectable wrinkle filler material: Report of a controlled, randomized, multicenter clinical trial of 251 subjects. Plast Reconstr Surg. 2004; 114:964-976
  2. ^ Sidwell, R.U.; Mcl Johnson, N; Francis, N. +; Bunker, C.B. Cutaneous sarcoidal granulomas developing after Artecoll® facial cosmetic filler in a patients with newly diagnosed system sarcoidosis. Clinical & Experimental Dermatology, 31(2):208-211. March 2006.
  3. ^ Rullan, Peter Paul M.D. Soft Tissue Augmentation using Artecoll: A Personal Experience. Facial Plastic Surgery. 20(2):111-116, May 2004.

External links


'"/>


(Date:9/19/2014)... structure could help predict how willing you are to take ... University found those with greater volume in a part of ... likely to engage in risky behavior than people with less ... the U.S. National Institute on Aging, involved two groups of ... researchers sought to determine how brain structure influences risk taking ...
(Date:9/19/2014)... FRIDAY, Sept. 19, 2014 (HealthDay News) -- Although ... key health benefits, most middle-aged and older adults ... type of exercise, according to new research. ... the muscle-strengthening recommendations set by the Department of ... Strength is essential for promoting health and ...
(Date:9/19/2014)... By Alan Mozes ... (HealthDay News) -- Cancer patients burdened by stress and ... for complications following their operation, a new study suggests. ... "deficit" appeared to have a nearly three times greater ... or good quality of life. "We,ve long known ...
(Date:9/19/2014)... York, NY (PRWEB) September 19, 2014 ... statin medication caused some patients to develop Type 2 ... litigation now underway in U.S. District Court, District of ... Status Report issued on September 12, 2014, discovery is ... things, the report noted that Pfizer, Inc., the manufacturer ...
(Date:9/19/2014)... using intact cells to treat and cure disease ... it is hindered by the inability of doctors and ... of these cells in patients without resorting to invasive ... September 17 in the online journal Magnetic Resonance ... San Diego School of Medicine, University of Pittsburgh and ...
Breaking Medicine News(10 mins):Health News:Brain Structure Might Help Predict Risky Behavior 2Health News:Adults Over 45 Not Meeting U.S. Muscle Strengthening Guidelines, Study Says 2Health News:Family Squabbles Can Derail Recovery From Cancer Surgery 2Health News:Family Squabbles Can Derail Recovery From Cancer Surgery 3Health News:Lipitor Lawsuits Move Forward, as Discovery Proceeds in Federal Multidistrict Litigation, Bernstein Liebhard LLP Reports 2Health News:Lipitor Lawsuits Move Forward, as Discovery Proceeds in Federal Multidistrict Litigation, Bernstein Liebhard LLP Reports 3Health News:A better way to track emerging cell therapies using MRIs 2
... By Jenifer Goodwin HealthDay Reporter , THURSDAY, ... antigen (PSA) levels are rising rapidly over time are of ... be done, a new study indicates. PSA is a ... of PSA can be a marker for prostate cancer, although ...
... By Amanda Gardner HealthDay Reporter , THURSDAY, Feb. ... plague will probably remain a scourge of centuries past, isolated ... fact, according to a just-released government report, a American lab ... of plague from a laboratory-acquired infection since 1959 and the ...
... , THURSDAY, Feb. 24 (HealthDay News) -- ... risk of cancer due to high radiation doses, and ... radiation exposure, a new study suggests. The researchers ... dialysis also have other health conditions that require them ...
... cancer organizations have recommended that men with a rapid rise ... there is no other indication and the PSA is within ... PSA velocityis a poor predictor of prostate cancer, and may ... online February 24 in the Journal of the National ...
... link between victimization experiences and substance abuse has been ... Chicago. The correlation is especially prevalent among gays, ... says Tonda Hughes, professor and interim head of health ... is lead author of the study, published in the ...
... THURSDAY, Feb. 24 (HealthDay News) -- A mouse heart rapidly ... a day after birth, scientists report. With this discovery, ... be found to help the human heart heal itself. ... but they,re somehow permanently switched off," said Eric Olson, co-senior ...
Cached Medicine News:Health News:Rapid Rise in PSA Levels a Poor Predictor of Prostate Cancer: Study 2Health News:Rapid Rise in PSA Levels a Poor Predictor of Prostate Cancer: Study 3Health News:Plague Kills U.S. Lab Worker 2Health News:Plague Kills U.S. Lab Worker 3Health News:Many Dialysis Patients at Risk for High Radiation Exposure 2Health News:PSA velocity screening for prostate cancer may lead to unnecessary biopsies 2Health News:Strong link found between victimization, substance abuse 2Health News:Scientists Say Newborn Mice Can Regrow Damaged Hearts 2
Other medicine definitionOther Tags