Navigation Links
Van Andel Research Institute Study Provides New Details of Fundamental Cellular Process
Date:1/23/2012

GRAND RAPIDS, Mich., Jan. 23, 2012 /PRNewswire/ -- A recent Van Andel Research Institute (VARI) study published in the journal Science investigating the molecular structure and function of an essential plant hormone could profoundly change our understanding of a key cell process, and might ultimately lead to the development of new drugs for a variety of diseases.

The study builds on earlier work by the same team of investigators at VARI that was published in the journal Nature in 2009. That study shed light on how plants respond when they are under stress from extreme temperatures, drought and other harsh environmental conditions and was later named by Science as one of the top scientific breakthroughs of 2009.

The current research conducted on the plant hormone Abscisic acid (ABA) determined that during signal transduction – the basic process of intercellular and intracellular communication – certain enzymes mimic the structure of the opposing enzyme. This insight may enable scientists to more accurately develop mechanisms to activate or inhibit intercellular and intracellular communication, which could lead to the development of plants that more readily survive drought or other conditions of stress.

In mammalian cells the ability to impact communication has numerous and far-reaching implications.  For example, applications that inhibit or activate cell communication in out-of-control metastasizing cancer cells have enormous potential to affect tumor growth.

"This type of finding once again demonstrates the importance of identifying, mapping and understanding fundamental cellular and molecular processes because of the profound implications for human health," said H. Eric Xu, Ph.D., Director of the VARI Center for Structural Biology and Drug Discovery and co-author of the current Science study.

The lead authors of the current Science study are Fen-Fen Soon, Ley-Moy Ng, a
'/>"/>

SOURCE Van Andel Research Institute
Copyright©2010 PR Newswire.
All rights reserved

Page: 1 2

Related biology technology :

1. LI-COR Biosciences and Mandel Scientific Company Inc. Announce Distribution Agreement
2. Van Andel Institute Joins the MetaMiner Oncology Partnership Program
3. Andrew P. Mandell - Mr. Diabetes(R) to Sit On ProtoKinetix Advisory Board
4. Takeda and Zinfandel Pharmaceuticals Sign Licensing Agreement for Alzheimers Disease Biomarker in Combination with Pioglitazone
5. Van Andel Institute Earns Highest "Green Building" Award
6. Dr. Lester Mandelker to Collaborate with Nuovo Biologics, LLC
7. Sandell Asset Management Seeks Sale of Rubicon & Tenon, Expansion of Board
8. Candelis and Microsoft Team Up to Empower Patients
9. Van Andel Institute Partners with UNCF to Recruit Students to Biomedical Research Careers
10. NIH Funds $1M Research at Quest Product Development and University of Colorado for New Digitally-Controlled Endoscopes
11. Canopus Biopharma and Leading Chinese Researcher Team Up to Treat Avian Influenza, to Prevent Possible Pandemic
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/31/2014)... California (PRWEB) July 31, 2014 CollabRx, ... that inform therapeutic decision-making in oncology, today announced that ... 14, 2014 to discuss the Company's financial results for ... an update about the business in the current fiscal ... call beginning on Thursday, August 14, 2014, at 5 ...
(Date:7/31/2014)... , July 31, 2014  Smith & Nephew ... medical technology business, today announced its entry into ... HAT-TRICK™ Lesser Toe Repair System. Comprised of three ... for metatarsophalangeal (MTP) ligament repair and reconstruction, a ... for proximal Inter-phalanges (PIP) fusion, also known as ...
(Date:7/31/2014)... Calif. (PRWEB) July 31, 2014 Held ... diagnosed patients with an overview of the disease and ... of drug side effects, as well as updates on ... grateful to Dr. Sandy Srinivas for organizing this educational ... of kidney cancer. “Sandy and her colleagues have put ...
(Date:7/31/2014)... The global market for molecular diagnostics is ... to a new study by Grand View Research, Inc. ... subsequent introduction of advanced cancer diagnostic technologies are expected ... next six years. Moreover, the growing global base of ... with disease triggering lifestyle habits such as smoking and ...
Breaking Biology Technology:CollabRx, Inc. Schedules First Quarter Fiscal Year 2015 Financial Conference Call and Business Update 2Smith & Nephew scores a HAT-TRICK with its entry into the high-growth hammer toe repair market 2Smith & Nephew scores a HAT-TRICK with its entry into the high-growth hammer toe repair market 3Smith & Nephew scores a HAT-TRICK with its entry into the high-growth hammer toe repair market 4Molecular Diagnostics Market - Global Industry Size, Share, Trends, Analysis, Players, Opportunity, Outlook and Forecast From 2014 to 2020 2Molecular Diagnostics Market - Global Industry Size, Share, Trends, Analysis, Players, Opportunity, Outlook and Forecast From 2014 to 2020 3Molecular Diagnostics Market - Global Industry Size, Share, Trends, Analysis, Players, Opportunity, Outlook and Forecast From 2014 to 2020 4Molecular Diagnostics Market - Global Industry Size, Share, Trends, Analysis, Players, Opportunity, Outlook and Forecast From 2014 to 2020 5
... , , SEATTLE, July 24 Cell ... today announced that the underwriter of its previously announced public ... to purchase up to 7,333,027 shares of its common stock ... shares of its common stock and warrants to purchase up ...
... for the first time, scientists studying the brain have worked ... team, including Professor Rodrigo Quian Quiroga at the Department of ... Itzhak Fried at the University California Los Angeles and Professor ... these findings in the journal Current Biology . It ...
... , ELM GROVE, Wis., July 23 With the ... the potential for error due to the communication process is considered ... Now or Never: A Primary Strategy to Improving Patient Safety, ... hand-off communication in an effort to improve patient ...
Cached Biology Technology:Cell Therapeutics, Inc. Announces Exercise of Overallotment 2Cell Therapeutics, Inc. Announces Exercise of Overallotment 3Oprah, Luke Skywalker and Maradona -- new study investigates how our brains respond to them 2Oprah, Luke Skywalker and Maradona -- new study investigates how our brains respond to them 3Free Webinar on Safer Clinical Hand-Offs Offered by Compirion Healthcare 2Free Webinar on Safer Clinical Hand-Offs Offered by Compirion Healthcare 3
(Date:7/31/2014)... study (HPV-023; NCT00518336) shows the sustained efficacy, ... virus (HPV) vaccine Cervarix. Women vaccinated with ... more than nine years, and vaccine efficacy ... is the longest follow-up report for a ... for the full paper. , HPV ...
(Date:7/31/2014)... in German . ... similar to a sponge that soaks up liquids. Hence, ... or greenhouse gases. However, loading of many MOFs is ... (KIT) now report in Nature Communications that ... surface. This can be prevented by water-free synthesis and ...
(Date:7/31/2014)... the photovoltaic effect in 1839, humankind has sought to ... its own purposes. In a new research report published ... FASEB Journal , scientists may have uncovered a ... focusing on a naturally occurring combination of lipids that ... over time and across speciessuggests that this specific natural ...
Breaking Biology News(10 mins):Sustained efficacy, immunogenicity, and safety for GlaxoSmithKline's HPV vaccine 2Sustained efficacy, immunogenicity, and safety for GlaxoSmithKline's HPV vaccine 3Free pores for molecule transport 2Scientists shine bright new light on how living things capture energy from the sun 2
... diseases can rival malaria,s ability to kill and cripple. Each year ... and more than a million mostly African children under the ... anniversary of the announcement of the genome sequence of the deadly ... Anopheles . A new book on malaria ...
... shelves until Oct. 2, it has already passed an enviable ... 100 books of all time. And they fit on ... of Genetics at Harvard Medical School and a founding core ... Harvard University, and his team encoded the book, Regenesis: How ...
... as carbon drains but are far from places where greenhouses ... has proposed human, agricultural and livestock waste, such as urine, ... large quantities of carbon dioxide and other greenhouse gases present ... occurring substance. A study published in the Journal of ...
Cached Biology News:New book tells story of 10-year-old malaria project 2New book tells story of 10-year-old malaria project 3Writing the book in DNA 2Writing the book in DNA 3A urine based 'potion' can act as a CO2 absorbent 2A urine based 'potion' can act as a CO2 absorbent 3
... Streptavidin-AP Systems provide rapid, precise localization ... in frozen or paraffin-embedded tissue, cytospins ... also facilitate double or triple labeleing ... simultaneously with primary antibodies of different ...
... Streptavidin-HRP Systems provide rapid, precise localization ... in frozen or paraffin-embedded tissue, cytospins ... also facilitate double or triple labeleing ... simultaneously with primary antibodies of different ...
... be used with all 96-well ... stacking of covered plates ... with automated systems ... are available for use with ...
... Chromatography requirements, IonQuest will provide ... The newly developed conductivity detector has ... ultra-low drift . The use ... creates even higher sensitivities for anions, ...
Biology Products: