Navigation Links
Vaccination reduces the risk of unvaccinated badger cubs testing tuberculosis positive
Date:12/12/2012

New evidence from a four-year field study has shown that BCG vaccination reduces the risk of tuberculosis infection in unvaccinated badger cubs in vaccinated groups, as well as in badgers that received the vaccine.

The research, published today in the journal PLOS ONE provides the strongest evidence to date that unvaccinated badger cubs can be indirectly protected from TB infection when some of the badgers in their social group are vaccinated. By studying rates of new cases of TB in cubs in vaccinated social groups, researchers have shown that the risk of non-vaccinated cubs testing positive was reduced by almost 80 per cent when more than a third of badgers in their group had been vaccinated.

The results come from a controlled clinical field trial of badger vaccination, conducted by the Animal Health and Veterinary Laboratories Agency (AHVLA) and the Food and Environment Research Agency (Fera), in an area in Gloucestershire where TB is highly prevalent in the badger population.

Dr Steve Carter of Fera and lead author of the latest research said: "One concern about the effectiveness of badger vaccination is that new-born cubs might acquire TB before they first emerge above ground. As the vaccine is not expected to benefit infected individuals it has been suggested that by the time cubs emerge and are available for vaccination they might have already been exposed to TB. Therefore, vaccination for them may be too late. This study indicates that vaccination of badgers above ground can indirectly protect unvaccinated cubs before they emerge from the sett".

The latest analyses were conducted by a team of scientists at Fera, AHVLA and the Universities of Newcastle and Strathclyde.

Professor Robbie McDonald, an author of the paper and now at the University of Exeter said: "This striking result in cubs shows a protective effect at the social group level and is important evidence that vaccination not only has a direct benefit to vaccinated badgers, but can also reduce the infectivity of TB within a badger social group that has been vaccinated."

But he cautioned: "Although this is an encouraging development, the costs and benefits of vaccinating badgers for controlling disease in cattle are not yet well understood".

"This means that it is a hard choice for farmers to make without further information and trials of how it would work in practice. The current Badger Vaccine Deployment Project in Gloucestershire and experience in the Welsh Government's badger vaccine project will help deliver this experience and knowledge."


'/>"/>

Contact: Louise Vennells
L.Vennells@exeter.ac.uk
44-139-272-2062
University of Exeter
Source:Eurekalert

Related biology technology :

1. Masaryk Memorial Cancer Institute Reduces Losses and Administrative Overhead With Ekahau RTLS
2. R&D/Leverages New Opti-Sim Virtual Prototyping Tool Saves Time and Money for PET Packaging Industry -- and Reduces Waste
3. Computer vision reduces risk in clinical trials
4. Phase II Data Presented at ACNP 2012 Shows Novel Antidepressant GLYX-13 Significantly Reduces Depression Scores Within Hours
5. Members of Congress, Cancer Experts Address Impact of Genetic Testing on Cancer
6. LABS, Inc. Earns AABB Accreditation for Donor Testing
7. Sigma-Aldrich to Acquire BioReliance; Extending Its Reach into Biopharmaceutical Testing and Services
8. India In Vitro Diagnostics Market Outlook to 2017- Clinical Chemistry Genetic Testing, Haematology, Histology and Cytology, Immuno Chemistry, Infectious Immunology and Microbiology Culture
9. HPV Testing for Cervical Cancer Risk Patients set to Increase
10. Premier Research Expands Salt Lake City and Phoenix Testing Facilities Adding 50% Capacity
11. Arsenic Testing Proves Organic Baby Formula Safe
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:4/25/2017)... (PRWEB) , ... April 25, 2017 , ... As part ... the series will explore the laboratory testing for DIC in order to illuminate this ... disorder which can occur in hospitalized patients resulting in a high degree of morbidity ...
(Date:4/25/2017)... PROVIDENCE, R.I. , April 25, 2017 /PRNewswire/ ... EpiVax, Inc. ("EpiVax") has licensed its novel immune-modulating technology ... in autoimmune disease and allergy. Tregitopes, ... discovered in human immunoglobulin by EpiVax CEO ... Martin. Similar to intravenous immunoglobulin G, an autoimmune ...
(Date:4/25/2017)... ... ... Leaders of Quorum Review IRB and Kinetiq , the ... week’s Association of Clinical Research Professionals (ACRP) 2017 Meeting & Expo with ... are excited to present subject matter expertise on topics that impact the global clinical ...
(Date:4/21/2017)... ... April 21, 2017 , ... ... manufactures in 10 categories with over 30 nominees and well as the first-year ... the new award and the event was hosted by CompanyWeek and Manufacturers Edge, ...
Breaking Biology Technology:
(Date:4/13/2017)... April 13, 2017 UBM,s Advanced Design and ... will feature emerging and evolving technology through its 3D ... will run alongside the expo portion of the event ... and demonstrations focused on trending topics within 3D printing ... and manufacturing event will take place June 13-15, 2017 at ...
(Date:4/11/2017)... MELBOURNE, Florida , April 11, 2017 ... "Company"), a security technology company, announces the appointment of independent ... John Bendheim to its Board of Directors, furthering the ... ... behalf of NXT-ID, we look forward to their guidance and ...
(Date:4/4/2017)... , April 4, 2017   EyeLock LLC , ... that the United States Patent and Trademark Office (USPTO) ... covers the linking of an iris image with a ... and represents the company,s 45 th issued patent. ... is very timely given the multi-modal biometric capabilities that ...
Breaking Biology News(10 mins):