Navigation Links
Unraveling the genetic picture of lung cancer
Date:10/22/2008

HOUSTON -- (Oct. 23, 2008) -- A study seeking possible cancer genes elucidated the mutations and the genetic pathways activated in the most common form of lung cancer lung adenocarcinoma and could lead to improved diagnosis and treatment, said the director of the Baylor College of Medicine Human Genome Sequencing Center that played a major role in the project led by the National Human Genome Research Institute.

In the report that appears in the Oct. 23 issue of the journal Nature, a national consortium of researchers called the Tumor Sequencing Project identified 26 genes that play a significant role in the development of lung adenocarcinoma as well as cellular pathways involved in the lung cancer. The analysis, involving 188 patients, more than any previous study, allowed scientists to find mutations associated with sub-types of the lung cancer such as those among non-smokers.

Lung adenocarcinoma kills an estimated 1 million people worldwide each year. As many as 10 percent of people with the disease are non-smokers. It is one of the deadliest cancers in men and women with only about 15 percent of those whom it strikes surviving five years.

The findings highlight the complexity of the disease. Along with the work from other groups which included analysis of gene expression, the mutation study undertaken by the BCM genome sequencing center and colleagues promises to unlock many of the secrets of cancer itself.

"Clearly, much still remains to be discovered. We have just begun to realize the tremendous potential of large-scale, genomic studies to unravel the many mysteries of cancer," said Dr. Richard Gibbs, a co-author of the lung adenocarcinoma paper and director of the BCM Genome Sequencing Center.

In the study, members of the consortium sequenced key candidate genes from 188 tumor samples and matching non-cancerous tissue from the same person. This approach enabled the BCM researchers to identif
'/>"/>

Contact: Glenna Picton
picton@bcm.edu
713-798-4712
Baylor College of Medicine
Source:Eurekalert

Page: 1 2

Related biology technology :

1. Digital Unions RT1(TM) Software Creates Telegenetics Network for Region 3 Genetics Collaborative
2. Response Genetics Reports Second Quarter 2007 Financial Results
3. ZymoGenetics Will Hold Conference Call Today at 5:00 p.m. Eastern Time to Provide Update on rThrombin
4. Clinical Data Acquires Epidauros Biotechnologie AG, Significantly Enhancing Proprietary Genetic Biomarker Portfolio
5. MedImmune Licenses Reverse Genetics Technology to Novartis for Use in Influenza Vaccine Development and Production
6. deCODE genetics to Webcast Presentation at Thomas Weisel Partners Annual Healthcare Conference
7. ZymoGenetics to Webcast Presentation at Two Upcoming Conferences
8. Interleukin Genetics Announces Management and Board Appointments
9. Response Genetics Announces Presentations/Webcasts at Upcoming Investor Conferences
10. Interleukin Genetics President and Chief Scientific Officer to Present at Immunotoxicology V Conference
11. CellCyte Genetics Corp. Forms Device Division to Develop and Manufacture Stem Cell Cultivation and Replication Products
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:6/2/2015)... 2015   Intrexon Corporation (NYSE: ... today the appointment of Olivier R. Jarry ... Mr. Jarry will lead the expansion of Intrexon,s programs ... for consumer markets.  Mr. Jarry ... in leading global life sciences and consumer health ...
(Date:6/2/2015)... China Cord Blood Corporation (NYSE: CO ) ("CCBC," the ... leading provider of cord blood collection, laboratory testing, hematopoietic stem ... the Special Committee of the Company,s board of directors (the ... China ) Limited as its independent financial advisor, ... United States legal counsel and Maples & ...
(Date:6/2/2015)... 02, 2015 Through rare discovery of ... Yancy Corporation is enabling World Scientists to actually ... biological sample, displaying the full nature (position, shape, size, ... , Jeff Porter, Co-Founder of the Yancy Corporation, says, ... – rare. They come once in a lifetime, if ...
(Date:6/2/2015)... New Orleans, LA (PRWEB) June 02, 2015 ... of custom gene synthesis to improve protein expression, announced ... The board includes six executives and entrepreneurs with a ... and software industries. , The team includes: , ... Startup Fund: , Roussel has a background in technology ...
Breaking Biology Technology:Intrexon Announces New Sector Leader 2Intrexon Announces New Sector Leader 3China Cord Blood Corporation's Special Committee Appoints Independent Financial Advisor and Legal Counsel to Evaluate Non-binding "Going Private" Proposal 2China Cord Blood Corporation's Special Committee Appoints Independent Financial Advisor and Legal Counsel to Evaluate Non-binding "Going Private" Proposal 3Scientists Eying Rare Discovery Of New Physics & Light Microscope Technology 2GenoCAD Announces New Board of Advisors, Improves Protein Expression Using Custom Gene Synthesis 2GenoCAD Announces New Board of Advisors, Improves Protein Expression Using Custom Gene Synthesis 3
... SYDNEY, Australia, Oct. 19 /Xinhua-PRNewswire-FirstCall/ --,Pharmaceutical company ... it had received approval to market Aridol ... Aridol is indicated for measuring airway hyperresponsiveness ... countries - Denmark, Finland, France, Germany,Greece, Ireland, ...
... today announced the launch of the Mattel UCLA ... personalized medicine for children, including the opportunities and ... world,s first dedicated solely to nanomedicine and pediatric ... nanopediatrics program? Because children are not small adults," ...
... Bunge Limited,(NYSE: BG ), an integrated, global agribusiness ... ended September 30, 2008, on Thursday,October 23, 2008, prior ... host a conference call at 10:00 a.m.,EDT on October ... listen to the conference call, please dial (877) 719-9791. ...
Cached Biology Technology:Pharmaxis Aridol Approved for Sale in Switzerland 2Mattel Children's Hospital UCLA launches program in nanopediatrics 2Bunge Limited Schedules Third Quarter 2008 Earnings Release and Conference Call 2
(Date:4/27/2015)...  For more than four decades, AUVSI,s Unmanned ... premier worldwide event for the unmanned land, sea, and ... for any local, national, or trade news organization interested ... and current applications of unmanned technologies. The conference will ... billion industry, and how it will soon impact the ...
(Date:4/21/2015)... 2015 High crime rate, ... boosting access control systems market in Saudi ... recently published report by TechSci Research " Saudi Arabia Access ... control systems market in Saudi Arabia ... access control systems market in the Kingdom is growing ...
(Date:4/17/2015)... Increasing adoption in ... to drive biometric systems market in ... According to a recently released TechSci Research ... biometric systems market in Saudi Arabia ... CAGR of over 22% through 2020. The market ...
Breaking Biology News(10 mins):UNMANNED SYSTEMS 2015: Largest International Conference and Trade Show for the Drone and Unmanned Technology Industry 2UNMANNED SYSTEMS 2015: Largest International Conference and Trade Show for the Drone and Unmanned Technology Industry 3UNMANNED SYSTEMS 2015: Largest International Conference and Trade Show for the Drone and Unmanned Technology Industry 4UNMANNED SYSTEMS 2015: Largest International Conference and Trade Show for the Drone and Unmanned Technology Industry 5Saudi Arabia Access Control Systems Market to Touch USD1.2 Billion by 2020 Says TechSci Research 2Saudi Arabia Access Control Systems Market to Touch USD1.2 Billion by 2020 Says TechSci Research 3Saudi Arabia Biometric Systems Market to Grow at 22% Through 2020, Says TechSci Research 2Saudi Arabia Biometric Systems Market to Grow at 22% Through 2020, Says TechSci Research 3
... of the long rows of shelves filled with sausages, ... space where daylight barely penetrates. Supermarkets use nearly ten ... the Fraunhofer Institute for Solar Energy Systems ISE in ... an integrated concept in collaboration with property developers, the ...
... (Spain) have manufactured a sheet that changes colour in the ... seen with the naked eye but when photographing the membrane ... metal can be quantified. Mercury contamination is a ... risk to public health since it accumulates in the brain ...
... have designed a guideline for physicians and patients on the ... subject develop reverse sex, which occurs when a subject looks ... low prevalence (it only affects one in 2000 people), and ... to the action of male hormones. This prevents individuals with ...
Cached Biology News:Aldi Süd supermarkets -- energy-optimized 2Aldi Süd supermarkets -- energy-optimized 3Mercury contamination in water can be detected with a mobile phone 2Study of a rare disease making people look like a woman but having male genitals under study 2
The 12-Tube Magnetic Separation Rack is designed to be used for small-scale separations using magnetic particles. ,Capacity: 12 microcentrifuge tubes. ,Magnets: Neodymium rare earth permanent ma...
Certified U.S. origin. Bovine Serum:, *Certified U.S. origin. Available raw, nonsterile filtered, or sterile filtered. , , *Sterility tested , , *Low Hemoglobin levels , , *Mycoplasma testing upon...
...
12(S)-HETE-d8 is used as an internal standard for the quantification of 12(S)-HETE by stable isotope dilution mass spectrometry....
Biology Products: