Navigation Links
University of Miami study finds RBAC to possess promising immunomodulating effects with respect to natural killer cell and cytokine activity

MIAMI, Aug. 15, 2012 /PRNewswire/ -- A published University of Miami study using Rice Bran Arabinoxylan Compound (RBAC) has showed  RBAC demonstrated significant immunomodulary activity based upon the observed changes in natural killer cell cytotoxicity (NKCC) and the cytokines and growth factors. Specifically, the study showed that the short term rise in NKCC and in 9 of 12 cytokines and growth factors are evident that RBAC is a potent immunomodulator. The study was published July 28, 2012 in Functional Foods in Health and Disease (Volume 2, Issue 7),

RBAC may help to destroy tumor cells and viruses directly, and increase the activity of immune cells, thereby optimizing the immune system, especially NKCC, which can increase the chance and speed of host recovery. Researchers note that the immunomodulatory activity merits further study in conditions where the immune system is functionally compromised, such as otherwise healthy smokers and HIV/AIDS or cancer patients.

RBAC is a nutritional supplement produced by enzymatic hydrolysis of hemicellulose B derived from rice bran. Several in vitro studies and clinical reports have shown RBAC to possess promising immunomodulating effects, specifically with respect to natural killer cell and cytokine activity.

The concept of a true immunomodulator is an agent possessing a broad range of activity dependent upon the existing state of health and immunity in the individual host. The Miami University study investigated the immunomodulatory effect of RBAC in a healthy adult human population over 60 days by assessing changes in NKCC and cytokines and growth factors.

According to Dr. John Lewis, Ph.D. associate professor, department of psychiatry and behavioral sciences at the University of Miami, Miller School of Medicine, and corresponding research author, this study represents a first step in testing this product in healthy adults. 

"We showed that the product is safe according to protein, bilirubin, and liver function tests, and that RBAC is capable of true immunomodulation, not stimulation or suppression," said Dr. Lewis. "In other words, the immune factors that we analyzed showed bi-directional, transient responses in people who were healthy without chronic disease," Dr. Lewis added.

"Our results are valid based on the statistical analysis that we performed in the study and appear to be consistent with the findings of other investigators as well," said Dr. Lewis.

The study was sponsored by Gardena, CA-based Daiwa Health Development. RBAC product for this study was supplied by Daiwa Health Development.

Dr. Aaron H. Wolfson, M.D., professor and vice chairman of the department of radiation oncology at the University of Miami, Miller School of Medicine, co-author in the study, and a proponent of RBAC since 2002, added, "we are eagerly looking to expand the use of RBAC in patients with end stage solid tumors (cancers) in the near future in a phase one trial as a preliminary study to evaluate PeakImunne4 as a potential therapeutic agent in treating these terminal patients."

RBAC is manufactured by Daiwa Health Development, and sold commercially as PeakImmune4®, an essential, broad spectrum immune support dietary supplement providing vital antioxidant and anti-inflammatory action. RBAC is a polysaccharide dietary fiber derived from rice bran and is modified by an enzyme from Shiitake mushrooms using a patented biotechnology process.

Daiwa has become a leading research and manufacturing company, striving to create new value in the field of bioscience in the U.S. and worldwide.

For complete study information call 877.434.3633 or email


For more Information:
Karena Dillon
Baker Dillon Group  


SOURCE Daiwa Health Development
Copyright©2012 PR Newswire.
All rights reserved

Related biology technology :

1. Northwestern University Joins VIVO Network with Elseviers SciVal Experts
2. Chicago Celebrates First Informatics Week, Co-Chaired by Intelligent Medical Objects and Northwestern University
3. Worlds smallest semiconductor laser created by University of Texas scientists
4. Genetics Policy Institute (GPI) Collaborates on Second Midwest Conference on Stem Cell Biology and Therapy, Oct. 5-7 at Oakland University
5. University of Utah physicists invent spintronic LED
6. University of Nottingham to play key role in European solar energy technology project
7. Western Carolina University, College of Business Appoints New Director of Entrepreneurship and Innovation
8. BioRestorative Therapies Enters Into Brown Fat Research Agreement With University of Utah
9. University of Utah chemists use nanopores to detect DNA damage
10. Stevenage Bioscience Catalyst to Welcome Cambridge University Researchers
11. RayBiotech, Inc. and the University of Oslo Enter into Antibody Array Services Collaboration
Post Your Comments:
(Date:11/24/2015)... Halozyme Therapeutics, Inc. (NASDAQ: HALO ) will be presenting at ... on Wednesday, December 2 at 9:30 a.m. ET/6:30 a.m. PT ... provide a corporate overview. th Annual Oppenheimer Healthcare ... ET/10:00 a.m. PT . Jim Mazzola , vice president ... --> th Annual Oppenheimer Healthcare Conference in ...
(Date:11/24/2015)... 2015  Clintrax Global, Inc., a worldwide provider of clinical research ... announced that the company has set a new quarterly earnings record ... quarter growth posted for Q3 of 2014 to Q3 of 2015. ... Mexico , with the establishment of an Asia-Pacific ... United Kingdom and Mexico ...
(Date:11/24/2015)... --> --> ... by Transparency Market Research, the global non-invasive prenatal testing ... 17.5% during the period between 2014 and 2022. The ... Analysis, Size, Volume, Share, Growth, Trends and Forecast 2014 ... to reach a valuation of US$2.38 bn by 2022. ...
(Date:11/24/2015)... , ... November 24, 2015 , ... InSphero AG, the ... cell culture models, has promoted Melanie Aregger to serve as Chief Operating Officer. ... served on the management team and was promoted to Head of InSphero ...
Breaking Biology Technology:
(Date:11/9/2015)... , Nov. 09, 2015 ... the addition of the "Global Law ... their offering. --> ) ... "Global Law Enforcement Biometrics Market 2015-2019" ... Research and Markets ( ) has ...
(Date:11/4/2015)... 2015 --> ... by Transparency Market Research "Home Security Solutions Market - Global ... - 2022", the global home security solutions market is expected to ... The market is estimated to expand at a CAGR ... 2022. Rising security needs among customers at homes, the ...
(Date:10/29/2015)... , Oct. 29, 2015   MedNet Solutions ... the entire spectrum of clinical research, is pleased to ... High Tech Association (MHTA) as one of only three ... the "Software – Small and Growing" category. The Tekne Awards ... who have shown superior technology innovation and leadership. ...
Breaking Biology News(10 mins):