Navigation Links
UCSB researchers identify the mechanisms underlying salt-mediated behaviors in fruit flies
Date:6/14/2013

(Santa Barbara, Calif.) Next time you see a fruit fly in your kitchen, don't swat it. That fly could have a major impact on our progress in deciphering sensory biology and animal behavior, including someday providing a better understanding of the human brain.

UC Santa Barbara researchers in the Department of Molecular, Cellular, and Developmental Biology (MCDB) and the Neuroscience Research Institute (NRI) have been studying the mechanisms underlying salt taste coding of Drosophila (fruit flies). And they have made some rather remarkable discoveries. Their findings appear today in the journal Science.

The work done by Craig Montell, Duggan Professor of MCDB and Neuroscience, and his team not only explains the fundamental question of how an animal chooses low salt over high salt, but also unravels the mechanism for how gustatory receptor neurons (GRNs) are activated by salt, an essential nutrient for all animals, including humans.

The fact that animals are attracted to low-salt foods and reject food with high salt is well known. However, it remains unclear how low-salt and high-salt taste perceptions are differentially encoded in gustatory receptor cells, and how they induce distinct behavioral responses. The researchers' findings solve this mystery.

Fruit flies use two distinct types of salt GRNs to respond to different concentrations of salt. One type is activated maximally by low salt and induces attractive feeding behavior. The other class, activated primarily by high salt, leads to aversive feeding behavior. Montell and his colleagues found that these two types of neurons compete with each other to regulate the animal's behavioral outputs. The net outcome of the salt behavioral response is determined by the relative strength of salt-attractive GRNs and salt-aversive GRNs. The identification of the mechanism underlying the coding of salt taste in GRNs represents a conceptual breakthrough.

"Ultim
'/>"/>

Contact: George Foulsham
george.foulsham@ia.ucsb.edu
805-893-3071
University of California - Santa Barbara
Source:Eurekalert

Page: 1 2 3

Related biology technology :

1. New England Biolabs Introduces Polbase, an Information Repository of Scientific Data for Polymerase Researchers
2. In new quantum-dot LED design, researchers turn troublesome molecules to their advantage
3. Multidisciplinary team of researchers develop world’s lightest material
4. Researchers shrink tumors and minimize side effects using tumor-homing peptide to deliver treatment
5. Innovative MetaMorph® NX Software Shatters Barriers Between Researchers and Image Analysis Goals with Exclusive Visual Workflow
6. UCLA researchers demonstrate fully printed carbon nanotube transistor circuits for displays
7. Penn and Brown researchers demonstrate earthquake friction effect at the nanoscale
8. Two Top Biological Imaging Centers Offer Powerful Free Online Tool to Researchers, Educators, and Public
9. Researchers develop one of the worlds smallest electronic circuits
10. MU researchers identify key plant immune response in fight against bacteria
11. Researchers realize high-power, narrowband terahertz source at room temperature
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:9/17/2014)... /PRNewswire/ - Oncothyreon Inc. (NASDAQ: ONTY ) ... shares of its Common Stock and Series A Convertible ... The Series A Convertible Preferred Stock is non-voting and ... conversion will be prohibited if, as a result, the ... 4.99% of the Common Stock then outstanding. As part ...
(Date:9/17/2014)... 17, 2014 Shimadzu Scientific ... Chromatograph (2D-LC), which offers a powerful separation ... The system provides a new level of ... is beneficial to scientists analyzing pharmaceutical impurities, ... products. , Comprehensive 2D-LC combines two independent ...
(Date:9/17/2014)... 17, 2014 JH Technologies ... located in Irvine. JH Technologies, a leader in ... recently announced an expanded partnership with Leica Microsystems into ... and image analysis solutions will be featured at the ... The new showroom facility is located within the JH ...
(Date:9/17/2014)... Franklin, MA (PRWEB) September 17, 2014 ... pre-engineered version of its TerraPure tank . This ... tanks is molded from FDA-compliant linear polyethylene and available ... seven pre-installed fittings and ships in two weeks or ... same features and benefits found in Terracon’s existing TerraPure ...
Breaking Biology Technology:Oncothyreon Announces Proposed Public Offerings 2Shimadzu’s New Nexera-e Two Dimensional Comprehensive Liquid Chromatograph Empowers Laboratories to Separate Even the Most Complex Mixtures 2JH Technologies displays newest microscope imaging technology at Southern California showroom grand opening 2JH Technologies displays newest microscope imaging technology at Southern California showroom grand opening 3Terracon Introduces Pre-Engineered TerraPure® Tank for Ultrapure Water Applications 2
... are used in a wide variety of applications ... and aerospace applications. Thermal analysis is routinely used ... growing trend to use nanostructured materials has made ... an atomic force microscope-based technique called nanoscale thermal ...
... laboratory has found a way to turn common carbon ... with properties expected to prove useful in electronic, optical ... scientist Pulickel Ajayan, in collaboration with colleagues in China, ... one-step chemical process that is markedly simpler than established ...
... cell therapy manufacturing division, Progenitor Cell Therapy ("PCT"), ... NBS ) ("NeoStem" or the "Company"), announced today ... and regulatory services related to the development of ... injectable suspension of microencapsulated insulin-producing, pancreatic islet cells ...
Cached Biology Technology:Magnetic actuation enables nanoscale thermal analysis 2Graphene quantum dots: The next big small thing 2Graphene quantum dots: The next big small thing 3Islet Sciences, Inc. Selects NeoStem's Manufacturing Subsidiary Progenitor Cell Therapy for Product Manufacturing 2Islet Sciences, Inc. Selects NeoStem's Manufacturing Subsidiary Progenitor Cell Therapy for Product Manufacturing 3Islet Sciences, Inc. Selects NeoStem's Manufacturing Subsidiary Progenitor Cell Therapy for Product Manufacturing 4
(Date:9/18/2014)... 18, 2014 Elsevier, a world-leading provider of ... and the Australasian Research Management Society (ARMS), recognized ... at the 5th Scopus Young Researcher of the ... today at the National Convention Centre and in ... attended by guests representing Australia,s and New Zealand,s ...
(Date:9/18/2014)... of camouflage: you don,t just blend in, the background ... uncommon as you might think. Kathryn Feller, from the ... larval life stages of many marine species are transparent. ... most creatures cannot make transparent. Feller explains that the ... eye unit with an opaque pigment to prevent light ...
(Date:9/17/2014)... affordable health care to reproductive technologies, the justice ... ability of people to identify key issues, articulate ... and find the most defensible ways forward. But ... these societal conversations?, The Hastings Center and the ... have teamed up to publish a series of ...
Breaking Biology News(10 mins):Elsevier and Australasian Research Management Society award scientists at Scopus ceremony 2Transparent larvae hide opaque eyes behind reflections 2Why bioethics literacy matters 2Why bioethics literacy matters 3
... Jizhou Song, a professor in the University of Miami ... Rogers, at the University of Illinois and Professor Yonggang ... for stretchable electronics that can be wrapped around complex ... The new mechanical design strategy is based on semiconductor ...
... Researchers from Joslin Diabetes Center, Boston, and ActiveSite ... have demonstrated that a specific inhibitor of the ... may provide a new therapeutic approach for treatment ... of diabetes. The study, which was partly funded ...
... that human male fertility is impacted by long-term exposure ... in the male reproductive tract, further suggesting a functional ... test to clarify mechanisms. Now, in a paper on ... the phenotype of mice genetically lacking FAAH, fatty acid ...
Cached Biology News:University of Miami engineer designs stretchable electronics with a twist 2Researchers describe protease inhibitor that may aid in diabetic retinopathy treatment 2Researchers describe protease inhibitor that may aid in diabetic retinopathy treatment 3February 2009 highlights from Biology of Reproduction 2
Smac/DIABLO (mouse) (CT) rabbit polyclonal antibody...
... to ADAMTS16 ( Abpromise for ... Antigen: Synthetic peptide based on ... Note: the amino acid sequence is ... 170690 SWISS ...
... Immunogen: KLH-conjugated, synthetic ... in which [ Ac K] corresponds to ... Accession Number: NM_003493 ... ~17kDa Quality Assurance: ...
synaptotagmin XIV-like [Source:RefSeq_peptide;Acc:NP_114120] Antigen: Recombinant Protein Epitope Signature Tag (PrEST)....
Biology Products: