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Tuberculosis Immunotherapy Grant for Immunoxel Honibe Honey Lozenges
Date:2/3/2013

enty clinical trials involving more than 1,500 TB and AIDS patients. These studies have demonstrated that herbal extract taken along with conventional drugs can clear bacteria in 2-4 months instead of usual 6-24 months. While these results are clearly in favor of Immunoxel, they are not ideal, since the duration of therapy is not optimal and faster-acting regimens are still needed. In order to overcome this drawback four types of solid, sublingual formulations of Immunoxel were made and tested clinically to see if they performed better.

The most optimal delivery vehicle was Honibe honey lozenge currently sold for sore throat and nasal congestion relief. The new version of Immunoxel was developed jointly by two Canadian companies, Island Abbey Foods Ltd., and Immunitor Inc. The project was funded by earlier-issued CRDF grant which was successfully completed last year. The outcome of the clinical trial was published in Immunotherapy – a peer-reviewed journal from Future Medicine – a science publisher based in London, UK.

“It is a great honor for me personally and for our Canadian and Ukrainian partners to be among winners of the STEP grant” stated John Rowe, President of Island Abbey Foods Ltd. “We are very proud to be able to contribute to the global fight against TB”. Dr. Allen Bain, Director of Immunitor Inc, another company based in Charlottetown, PEI, and co-recipient of the grant added: "This success will help boost our fundraising efforts for expanded multinational trials and marketing in high TB burden countries in Africa and Asia. The ultimate Idea to Market goal endorsed by CRDF is thus fulfilled".

The anti-mycobacterial activity of honey has been known since ancient times and it is used as a folk medicine even today. Several in vitro studies demonstrated the direct inh
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