Navigation Links
Tricking algae's biological clock boosts production of drugs, biofuels
Date:11/7/2013

Tricking algae's biological clock to remain in its daytime setting can dramatically boost the amount of valuable compounds that these simple marine plants can produce when they are grown in constant light.

That is the conclusion of a "proof of concept" experiment described in the Dec. 2 issue of the journal Current Biology. The study found that when the biological clocks of cyanobacteria (blue-green algae) were stopped in their daylight setting, the amount of several biomolecules that they were genetically altered to produce increased by as much as 700 percent when grown in constant light.

"We have shown that manipulating cyanobacteria's clock genes can increase its production of commercially valuable biomolecules," said Carl Johnson, Stevenson Professor of Biological Sciences at Vanderbilt University, who performed the study with collaborators at the J. Craig Venter Institute in Rockville, MD and Waseda University in Tokyo. "In the last 10 years, we have figured out how to stop the circadian clocks in most species of algae and in many higher plants as well, so the technique should have widespread applicability."

If it lives up to its promise, bioclock stopping could have significant economic benefits: Microalgae are used for a wide variety of commercial applications ranging from anti-cancer drugs to cosmetics to bioplastics to biofuels to neutraceuticals. In addition, biotech companies are currently rushing to set up "biofactories" that use microorganisms to create a wide variety of substances that are too difficult or expensive to synthesize using conventional chemical methods. Many of them are based on microorganisms that have biological clocks.

In 2004, Johnson was a member of the team that determined the molecular structure of a circadian clock protein for the first time. Subsequent work mapped the entire clock mechanism in cyanobacteria, which is the simplest bioclock found in nature. The researchers discover
'/>"/>

Contact: David Salisbury
david.salisbury@vanderbilt.edu
615-343-6803
Vanderbilt University
Source:Eurekalert  

Page: 1 2

Related biology technology :

1. Two Top Biological Imaging Centers Offer Powerful Free Online Tool to Researchers, Educators, and Public
2. Chemring Detection Systems Awarded $9M for Biological Detection Systems
3. Scientists develop tools to make more complex biological machines from yeast
4. Biodetection 2012 Conference Brings Together Leading Organizations from Around the World to Address Challenges & Technology Advances in Detection and Identification of Biological Threats in Washington, DC from June 28-29, 2012
5. "Biological Control Industry Overview: Companies & Products" Edition 2 is Here. Critical information for Understanding the Global Biopesticide/Biocontrol Market
6. PhoenixSongs Biologicals, Inc. Announces Enhanced Neural Lineage-specific Cell Culture Media Products Release
7. Society of Biological Psychiatry and Elsevier Renew Publishing Agreement
8. Three Hertz Foundation Fellows Receive Presidential Honors; Leaders in Applied Physical, Biological and Engineering Sciences
9. GenScript Announces Collaboration with AMDeC: Seeks to Decrease Biological Research Costs at NYC Area Institutions
10. Uncovering the Meaning in Your NGS Data: Tackling the Biological Analysis and Interpretation of Sequence Variation
11. Novus Biologicals Hires David Eansor to Lead New Corporate-Development Effort
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Tricking algae's biological clock boosts production of drugs, biofuels
(Date:2/27/2015)... 2015 A paper published today, " ... " in Science Translational Medicine, demonstrates ... reduce the risk associated with investing in the ... levels of funding for developing so-called "orphan" drugs. ... collaboration between scientists at the National Center for ...
(Date:2/27/2015)... 2015 Bionomics Limited (ASX:BNO, ADR:BMICY) is to ... BNC105 in patients with metastatic renal cancer at the ... . The data will be presented by Dr. ... Comprehensive Cancer Center in California ... data identifies Ferritin and IL-8 as two baseline biomarkers ...
(Date:2/27/2015)... , Feb. 27, 2015  Steep Hill, the industry ... and internationally, intends to open a full service medical ... Mexico , bringing advanced scientific tools and methodology ... Steep Hill is currently the only laboratory licensed ... potency and contaminant testing in order to meet the ...
(Date:2/26/2015)... , Feb. 26, 2015  23andMe, the leading personal ... Black as Privacy Officer and Corporate Counsel. Black ... privacy laws as well as health care regulations. As ... will be responsible for reviewing, updating and enhancing the ... U.S. and abroad. She joined the company January 5, ...
Breaking Biology Technology:New Financing Technique May Hold Key to Unlocking Funding for Rare Diseases 2New Financing Technique May Hold Key to Unlocking Funding for Rare Diseases 3New Financing Technique May Hold Key to Unlocking Funding for Rare Diseases 4New BNC105 Biomarker Data to be Presented at US Cancer Conference 2New BNC105 Biomarker Data to be Presented at US Cancer Conference 3New BNC105 Biomarker Data to be Presented at US Cancer Conference 4New BNC105 Biomarker Data to be Presented at US Cancer Conference 5Steep Hill First to Receive Provisional Approval to Establish Laboratory Services for Cannabis Testing in State of New Mexico 223andMe Appoints Kate Black as Privacy Officer and Corporate Counsel 2
... equipment manufacturer Gehl Co. has developed a new ... functions using a compact, wireless remote control pendant from outside ... hand-held pendant can be used to raise, lower, extend and ... , ,"Our goal was to add a new dimension of ...
... years of living on government pay, I'm finally banking a few bucks. ... few others, and getting paid by a law firm and an accounting ... to speak, which might surprise those folks who poked fun at "the ... I didn't admit it: I miss the flags, fanfare and fun of ...
... The Medical College of Wisconsin has been awarded ... Medical Countermeasures against Radiation, an effort to take the college's ... radiation. , ,The institute is one of seven centers being ... Diseases (NIAID) to establish a plan for identifying and ...
Cached Biology Technology:Reading Tommy Thompson's diary: Imagining unspoken thoughts about 2008 2Reading Tommy Thompson's diary: Imagining unspoken thoughts about 2008 3Medical College getting $18.1 million to study radiation damage treatments 2
(Date:2/24/2015)... YORK , Feb. 24, 2015 This report ... The report provides separate comprehensive analytics for the US, ... Europe , Asia-Pacific , ... . Annual estimates and forecasts are provided for the ... provided for these markets. Market data and analytics are derived ...
(Date:2/24/2015)... , Feb. 24, 2015 Research and ... the addition of the "Global 2D Gesture ... The analysts forecast the Global ... CAGR of 32.12% over the period 2014-2019 ... in non-traditional sectors is one of the major ...
(Date:2/19/2015)... , Feb .19, 2015 Research and ... the addition of the "Military Electro-Optical / ... Sensor Technology, by Platform - Forecast to 2020" ... The military electro-optical/infrared systems market is expected to ... CAGR of 7.71%. This report segments ...
Breaking Biology News(10 mins):World Iris Biometrics Industry 2World Iris Biometrics Industry 3World Iris Biometrics Industry 4World Iris Biometrics Industry 5World Iris Biometrics Industry 6World Iris Biometrics Industry 7World Iris Biometrics Industry 8World Iris Biometrics Industry 9World Iris Biometrics Industry 10World Iris Biometrics Industry 11Global 2D Gesture Recognition Market 2015-2019 with Cognitec Systems, CogniVue, eyeSight Mobile Technologies & PointGrab Dominating 2Military Electro-Optical / Infrared Systems (Image Intensification, Laser, Infrared) Market - Forecast to 2020: Featuring Profiles of the Market Leaders on this $16 Billion market 2Military Electro-Optical / Infrared Systems (Image Intensification, Laser, Infrared) Market - Forecast to 2020: Featuring Profiles of the Market Leaders on this $16 Billion market 3
... study calling for levels of obesity among South Asians to ... of Leicester. A team from the University,s Departments ... for the point at which South Asians should be classed ... published in PLoS One , a journal of the ...
... Management Institute ( http://cmi.vt.edu/ ), a research center ... Environment, has provided technical expertise for the world,s ... Forest Degradation (REDD) project to receive certification under ... ( http://www.v-c-s.org/ ). The UN-REDD Programme ( http://www.un-redd.org/ ...
... to scientists, carbon monoxide (CO), a tasteless, colorless and odorless ... also highly toxic to human beings. Found in the exhaust ... killer" because excessive inhalation is lethal, poisoning the nervous system ... Itzhak Schnell of Tel Aviv University,s Department of Geography and ...
Cached Biology News:New research calls for lower limit to be set for South Asian obesity level 2First UN carbon offset project certified 2Carbon monoxide -- the silent calmer? 2
... Sophions newly introduced QPatch HT is taking automated ... powerful level. With its ability to generate thousands ... is enabling new screening paradigms in ion channel ... with the same high quality afforded by conventional ...
... mouse embryonic stem cells to dopaminergic neurons. ... where they are mainly located in the ... the retrorubral field. These dopaminergic (DA) neurons ... ( e.g.projections to the caudate nucleus, putamen ...
... Microarrays designed for RNA aptamer screening and ... and powerful Paraflo microfluidic on-chip synthesis platform. ... be synthesized on-chip and LC Sciences can ... microarrays are available as part of our ...
... the C-terminal end of the mouse retinoic acid receptor beta (RAR*). ... of RAR*. The sequence of PEP-005 is (amino to carboxy terminus): ... S - S - V - E - N - S - ... L - L - Q (The N-terminal cysteine has been added ...
Biology Products: