Navigation Links
Tricking algae's biological clock boosts production of drugs, biofuels
Date:11/7/2013

Tricking algae's biological clock to remain in its daytime setting can dramatically boost the amount of valuable compounds that these simple marine plants can produce when they are grown in constant light.

That is the conclusion of a "proof of concept" experiment described in the Dec. 2 issue of the journal Current Biology. The study found that when the biological clocks of cyanobacteria (blue-green algae) were stopped in their daylight setting, the amount of several biomolecules that they were genetically altered to produce increased by as much as 700 percent when grown in constant light.

"We have shown that manipulating cyanobacteria's clock genes can increase its production of commercially valuable biomolecules," said Carl Johnson, Stevenson Professor of Biological Sciences at Vanderbilt University, who performed the study with collaborators at the J. Craig Venter Institute in Rockville, MD and Waseda University in Tokyo. "In the last 10 years, we have figured out how to stop the circadian clocks in most species of algae and in many higher plants as well, so the technique should have widespread applicability."

If it lives up to its promise, bioclock stopping could have significant economic benefits: Microalgae are used for a wide variety of commercial applications ranging from anti-cancer drugs to cosmetics to bioplastics to biofuels to neutraceuticals. In addition, biotech companies are currently rushing to set up "biofactories" that use microorganisms to create a wide variety of substances that are too difficult or expensive to synthesize using conventional chemical methods. Many of them are based on microorganisms that have biological clocks.

In 2004, Johnson was a member of the team that determined the molecular structure of a circadian clock protein for the first time. Subsequent work mapped the entire clock mechanism in cyanobacteria, which is the simplest bioclock found in nature. The researchers discover
'/>"/>

Contact: David Salisbury
david.salisbury@vanderbilt.edu
615-343-6803
Vanderbilt University
Source:Eurekalert  

Page: 1 2

Related biology technology :

1. Two Top Biological Imaging Centers Offer Powerful Free Online Tool to Researchers, Educators, and Public
2. Chemring Detection Systems Awarded $9M for Biological Detection Systems
3. Scientists develop tools to make more complex biological machines from yeast
4. Biodetection 2012 Conference Brings Together Leading Organizations from Around the World to Address Challenges & Technology Advances in Detection and Identification of Biological Threats in Washington, DC from June 28-29, 2012
5. "Biological Control Industry Overview: Companies & Products" Edition 2 is Here. Critical information for Understanding the Global Biopesticide/Biocontrol Market
6. PhoenixSongs Biologicals, Inc. Announces Enhanced Neural Lineage-specific Cell Culture Media Products Release
7. Society of Biological Psychiatry and Elsevier Renew Publishing Agreement
8. Three Hertz Foundation Fellows Receive Presidential Honors; Leaders in Applied Physical, Biological and Engineering Sciences
9. GenScript Announces Collaboration with AMDeC: Seeks to Decrease Biological Research Costs at NYC Area Institutions
10. Uncovering the Meaning in Your NGS Data: Tackling the Biological Analysis and Interpretation of Sequence Variation
11. Novus Biologicals Hires David Eansor to Lead New Corporate-Development Effort
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Tricking algae's biological clock boosts production of drugs, biofuels
(Date:4/27/2015)... 2015 SynGen Inc., a company that focuses ... harvest stem and progenitor cells from umbilical cord blood, ... that it has added three new members to its ... Business Units focus on product commercialization. ... Vice President and Chief Financial Officer.  Chuck was most ...
(Date:4/27/2015)... , Germany , April 27, ... in treatment of millions of cancer patients   ... patent in Europe entitled "Tissue ... discovery that EPHB4 is a novel receptor for Erythropoietin (EPO), where ... the production of red blood cells and is prescribed ...
(Date:4/27/2015)... 2015  MT Services LLC, a Lawsuit Settlement ... that U.S. District Judge Joseph Goodwin ... status meeting in hopes to resolve more than ... manufacturers who are involved in multidistrict litigations under ... going on for some time, and Judge Goodwin ...
(Date:4/27/2015)... (PRWEB) April 27, 2015 Diasome ... an agreement with Joslin Diabetes Center (“Joslin”) to ... study of Diasome’s novel Hepatocyte Directed Vesicle (“HDV”) ... 1 diabetes. , Located in Boston, Massachusetts, ... care and education organization dedicated to the prevention, ...
Breaking Biology Technology:SynGen Inc. Expands Its Management Team 2Molecular Health Gains Patent for Novel Receptor Utilizing Computational Biomarker Discovery Technology 2Transvaginal Mesh Lawsuit News: Another Joint Conference Status Meeting Ordered by Judge to Resolve More than 70K TVM Lawsuits against Several Mesh Manufacturers, Says Lawsuitsettlementnews.com 2Transvaginal Mesh Lawsuit News: Another Joint Conference Status Meeting Ordered by Judge to Resolve More than 70K TVM Lawsuits against Several Mesh Manufacturers, Says Lawsuitsettlementnews.com 3Diasome Pharmaceuticals Announces Clinical Trial Design Collaboration 2
... June 1 /PRNewswire-Asia-FirstCall/ -- Dehaier Medical Systems Ltd.,(Nasdaq: DHRM ... products in China , said today that it has become the ... Penlon, a UK firm specializing in anesthesia and breathing equipment for 60,years. ... ...
... CITY, Kan. , June 1 Oncimmune ... test that aids physicians in risk assessment and the ... results demonstrating the diagnostic and economic benefits of a ... significantly improve the prognosis for lung cancer patients. Currently, ...
... ... eLadder® Safety course series into its curriculum. The online drug safety training courses ... to enrolled PharmD and PhD students, postdoctoral fellows, and residents via the University of ... ...
Cached Biology Technology:Dehaier Medical Systems Extends Product Offerings with Exclusive Distribution Agreement for Penlon Anesthesia System in North China 2Dehaier Medical Systems Extends Product Offerings with Exclusive Distribution Agreement for Penlon Anesthesia System in North China 3Dehaier Medical Systems Extends Product Offerings with Exclusive Distribution Agreement for Penlon Anesthesia System in North China 4Studies Demonstrate Early Stage Detection and Economic Benefits of a Blood-Based Test for Lung Cancer 2Studies Demonstrate Early Stage Detection and Economic Benefits of a Blood-Based Test for Lung Cancer 3Studies Demonstrate Early Stage Detection and Economic Benefits of a Blood-Based Test for Lung Cancer 4Studies Demonstrate Early Stage Detection and Economic Benefits of a Blood-Based Test for Lung Cancer 5Studies Demonstrate Early Stage Detection and Economic Benefits of a Blood-Based Test for Lung Cancer 6Studies Demonstrate Early Stage Detection and Economic Benefits of a Blood-Based Test for Lung Cancer 7University of Maryland School of Pharmacy Adopts BioSoteria's eLearning Drug Safety Courses 2University of Maryland School of Pharmacy Adopts BioSoteria's eLearning Drug Safety Courses 3University of Maryland School of Pharmacy Adopts BioSoteria's eLearning Drug Safety Courses 4
(Date:4/8/2015)... , April 8, 2015  Infinisource, a ... and services, and Morpho, a leading supplier of ... to produce the market,s most advanced biometrically-enabled time ... iSolved NXG time clock is setting a bold, ... labor data for the small and mid-size employer. ...
(Date:4/2/2015)... 2, 2015 Fingerprint Cards (FPC) ... FPC1025 from the distributor World Peace Industrial Group (WPI), ... 2015 although the major part of the shipments will ... used by smartphone manufacturers in China ... in the communicated revenue guidance of + 1 000 MSEK ...
(Date:3/30/2015)... 2015 Research and Markets ( http://www.researchandmarkets.com/research/lc9bnl/global_gesture ... Gesture Recognition Market in Automotive Sector 2014-2018" report ... Global Gesture Recognition market in Automotive Sector to grow ... Gesture recognition is the ability of a ... an individual. Gesture recognition technology can be 2D-based or ...
Breaking Biology News(10 mins):iSolved Time Clock Offers Unmatched Accuracy due to Morpho Biometrics 2iSolved Time Clock Offers Unmatched Accuracy due to Morpho Biometrics 3Fingerprint Cards Receives Touch Fingerprint Sensor Order of SEK 110 Million 2Global Gesture Recognition Market in Automotive Sector Report 2015 - Growing Number of Partnerships 2
... new University of Central Florida study will examine how rising ... Florida Panhandle and Alabama and Mississippi coasts. The research, ... Engineering, is a response to scientific studies that show sea ... research also could potentially be linked with models of how ...
... German . An international team of researchers, including ... San Francisco (USA) and Dr. Shannon McPherron of the Max ... evidence that human ancestors were using stone tools and consuming ... earlier than previously documented. While working in the Afar region ...
... mantle reservoir on Baffin Island in the Canadian Arctic. Geologist ... the finding--the first discovery of what may be a primitive ... The Earth,s mantle is a rocky, solid shell that is ... up about 84 percent of the Earth,s volume. The mantle ...
Cached Biology News:Study to examine rising sea level's impact on estuaries, coastal communities 2Scientists discover oldest evidence of human stone tool use and meat-eating 2Scientists discover oldest evidence of human stone tool use and meat-eating 3Scientists discover oldest evidence of human stone tool use and meat-eating 4Oldest Earth mantle reservoir discovered 2
Human Serum FDA Licensed US Donor Centers Sterile / Non-sterile: Sterile Filtered to 0.2 micron Information: Extensive Viral Testing ...
Normal human AB serum, pooled...
Human alpha-1-antitrypsin. No cross-reactivity with alpha-1-acid glycoprotein, serum albumin or other serum proteins....
Human/Mouse/Rat JNK Pan Specific Affinity Purified PAb...
Biology Products: