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Thomson Reuters Research Forecasts the Onset of the Targeted Drug Discovery Era
Date:12/22/2011

PHILADELPHIA and LONDON, Dec. 22, 2011 /PRNewswire/ -- In recognition of the International Year of Chemistry 2011, Thomson Reuters published a research report analyzing The Changing Role of Chemistry in Drug Discovery. By tracking pharmaceutical industry data over the last decade along with insights from industry experts, the new report forecasts the end of the blockbuster drug era. In its place, the report suggests, a much more targeted, patient-specific approach will define the next decade for the pharmaceutical industry and the patients it serves.

(Photo:  http://photos.prnewswire.com/prnh/20111222/NY26822 )

Leveraging data and analytics from the Thomson Reuters Integrity drug discovery database, the report analyzes pharmaceutical industry productivity, patent data, changing dynamics in the new drug pipeline and trends in the use of biomarkers, among several other factors. Following are some of the key findings in the new report:

  • Improved Strategies for Development: Sales of pharmaceutical products have increased almost two and a half times since 2000, yet it is taking approximately 20 percent longer to get new drugs to market. To remain competitive, major pharmas are utilizing innovative new development strategies to improve output.
  • Repurposed Drugs Create New Opportunities: The high cost of drug discovery has led companies to repurpose existing drugs for rare diseases, increasing their return on investment and driving overall development costs down, while also addressing the needs of individuals suffering from these "rare" illnesses. Repurposed drugs have grown from approximately 80 in 2001 to 222 by 2010, a 300 percent increase.
  • Growing Role of Biopharmaceuticals: While new chemical entities
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