Navigation Links
Therapeutic Cells Derived From Reprogrammed (iPS) Stem Cells Display Early Aging
Date:2/10/2010

he study. "Fortunately, we think the problem may be related to the use of viruses.  Preliminary results suggest that these abnormalities are significantly reduced using stem cells generated without the use of viruses or genetic manipulation.  Although there is excitement that iPS cells can serve as an embryo-free source of stem cells, it would premature to abandon research using embryonic stem cells until we fully understand what's causing these problems."    

Rapid progress is being made towards controlled differentiation of human iPS cells into specific tissue types, such as heart, liver, and eye including retinal pigment epithelium (RPE).  Although these studies clearly suggest a similar differentiation potential between iPS and embryonic stem cells, it is unclear whether they can be expanded into homogeneous cell populations suitable for use in drug discovery and clinical translation.  

"A major hallmark of ES-derived cells is the high recovery and proliferative capability of the cells," stated Shi-Jiang Lu, Ph.D., Senior Director of Stem International and co-senior author of the paper. "We compared the characteristics of cells derived from iPS and ES cells, and found that blood and vascular derivatives from iPS cells display abnormal molecular and/or cellular processes compared to their corresponding ESC counterparts. Similarly, RPE cells derived from iPS cells began senescing in the first passage, indicating the observed phenomenon is not limited to hemangioblastic lineages."

"More research is clearly needed before we can advance iPS cell technology into the clinic," stated William M. Caldwell, CEO and Chairman of ACTC.  "However, until this technology is perfected, we believe embryonic stem cells will play an important role in helping patients suffering from a range of debilitating diseases."  

The research
'/>"/>

SOURCE Advanced Cell Technology, Inc.
Copyright©2010 PR Newswire.
All rights reserved

Page: 1 2 3 4

Related biology technology :

1. United Therapeutics Corporation to Announce Fourth Quarter and Annual 2009 Financial Results Before Market Open on Tuesday, February 16, 2010
2. Corgenix and Tulane Announce Award of Additional NIH Contract to Expand Lassa Fever Research Towards Development of Vaccines and Improved Therapeutic Agents
3. Amicus Therapeutics Board of Directors Names Chief Executive Officer John F. Crowley Chairman of the Board
4. Silence Therapeutics to Present at 12th Annual BIO CEO & Investor Conference
5. Aegera Therapeutics Initiates a Randomized Phase 2 Study with AEG35156 for the Treatment of Hepatocellular Carcinoma
6. Oxygen Biotherapeutics, Inc. Outlines Plans for New Products During Investor Conference Presentation
7. The Honorable Tommy G. Thompson Joins the United Therapeutics Corporation Board of Directors
8. Cell Therapeutics Commits to PhRMAs Code on Interactions With Healthcare Professionals
9. WellGen, Inc. and RFI Ingredients to Collaborate on Therapeutic Nutrition Opportunities
10. Reportlinker Adds The Future of Orphan Diseases Therapeutics - Market Forecasts to 2015, Pipeline Analysis and Reimbursement
11. Dennis Winger Joins Nektar Therapeutics Board of Directors
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:8/28/2015)... ... August 28, 2015 , ... ... organized and will present a session on chemical spectroscopic imaging at JASIS 2015 ... exposition is Asia’s largest analytical and scientific instruments show which will be held ...
(Date:8/27/2015)... , ... August 27, 2015 , ... ... for venture capital funds, investment firms and animal health companies to hear from ... raised $160 million. Several have also received licensing agreements or distribution contracts. ...
(Date:8/27/2015)... 2015 The National Necrotizing Fasciitis Foundation ... saved by doctors at Vanderbilt University Hospital in ... Pharmaceuticals and Dr. John Crew , director of ... Medical Center in Daly City, CA. ... approach, pioneered by Dr. Crew, that had previously saved ...
(Date:8/27/2015)... NEW YORK , August 27, 2015 ... on enhancing image processing functions in the human vision system, ... Angeles point guard Chris Paul to ... basketball players who want to improve their real-life on-court performance. ... on the court, whether it is shooting a ball or ...
Breaking Biology Technology:U.S. Symposium on Imaging Organized by Pittcon’s Program Chairman Chuck Gardner 2U.S. Symposium on Imaging Organized by Pittcon’s Program Chairman Chuck Gardner 3VetStem Biopharma, Inc. Among Seventeen Companies Selected to Present at the KC Animal Health Investment Forum on September 1st 2015 2VetStem Biopharma, Inc. Among Seventeen Companies Selected to Present at the KC Animal Health Investment Forum on September 1st 2015 3Patient's Life and Eyes Saved from Gruesome Flesh-Eating Infection Consuming Her Face 2Patient's Life and Eyes Saved from Gruesome Flesh-Eating Infection Consuming Her Face 3Eight-Time All-Star Chris Paul and GlassesOff Partner to Develop Innovative Mobile App Designed to Improve On-Court Performance 2Eight-Time All-Star Chris Paul and GlassesOff Partner to Develop Innovative Mobile App Designed to Improve On-Court Performance 3
... Z. Yang, Varian, Inc. , ... Bisphenol A (BPA) is a primary raw ... and polycarbonate plastic. 4-Nonylphenol (4-NP) is a degradation product of alkylphenol ... is also widely used as an additive in plastics that are ...
... (FRET) between GFP , fusions in lysates of the yeast ... Cary Eclipse , ... Daren J. Fyfe, Ph.D* , ... Clayton campus Victoria 3800, Australia , ...
... , Increased throughput in drug ... N-in-1 experiments. Patented LINAC collision cell technology plays a key role in ... Overview , ... an important impact is in N-in-1 studies (also referred to as cassette ...
Cached Biology Technology:Analysis of Phenolic Estrogen Mimics in River Water by Negative Ion Electrospray LC/MS/MS 2 Monitoring fluorescence resonance energy transfer (FRET) between GFP, fusions in lysates of the yeast Saccharomyces cerevisiae using the , Varian, Cary Eclipse 2 Monitoring fluorescence resonance energy transfer (FRET) between GFP, fusions in lysates of the yeast Saccharomyces cerevisiae using the , Varian, Cary Eclipse 3 Monitoring fluorescence resonance energy transfer (FRET) between GFP, fusions in lysates of the yeast Saccharomyces cerevisiae using the , Varian, Cary Eclipse 4Detection of N-in-1 Experiments: Extending the Range of N Using the API 3000 LC/MS/MS System 2Detection of N-in-1 Experiments: Extending the Range of N Using the API 3000 LC/MS/MS System 3
(Date:8/6/2015)... 2015  Today, U.S. Congressman Mike Honda ... to learn firsthand how Silicon Valley technologies can ... a world leader in multi-factor identity management and ... federal agencies and commercial organizations achieve new levels ... "The vast majority of network breaches can be ...
(Date:8/5/2015)... According to a new market ... Services, Vertical (BFSI, Airport, IT & Telecom, Utilities, Education, ... to 2020", published by MarketsandMarkets, defines and segments the ... segments. The global PIAM Market is estimated to grow ... 2019, at a CAGR of 14.9 % from 2014 ...
(Date:8/4/2015)... , Aug. 04, 2015 ... ) has announced the addition of the ... Software, and Service), Sub-Segment (Computer Forensics, Network ... Tool Types, Service, Vertical and Region - ... their offering. By Component (Hardware, ...
Breaking Biology News(10 mins):Rep. Honda to Visit Crossmatch in Redwood City 2Physical Identity and Access Management Market Worth $546.2 Million by 2019 2Physical Identity and Access Management Market Worth $546.2 Million by 2019 3Physical Identity and Access Management Market Worth $546.2 Million by 2019 4Digital Forensics Market - The Market Represents a Compound Annual Growth Rate (CAGR) of 11.3% From 2015 to 2020 2
... A destructive spring freeze that chilled the eastern United States ... poses to plants and crops, according to a paper just ... a team from the Department of Energy,s Oak Ridge National ... in on an ill wind. Plants had been sending out ...
... Dr. Joseph Lipsick (Stanford University) and colleagues demonstrate that ... tumor suppressor gene function together in the Drosophila MMB/dREAM ... Drosophila MMB/dREAM includes proteins encoded by the Myb oncogene ... well as the E2F2 protein which itself binds to ...
... is available in German . , Iron ... component of hemoglobin, the substance that makes our blood red ... cause heavy damage; it is thought that iron deposits in ... as Parkinsons, Huntington s, and Alzhiemers. A malfunction of the ...
Cached Biology News:Killer freeze of '07 illustrates paradoxes of warming climate 2Rusty worms in the brain 2
Ca2+ Channel Ca gamma 2 Purified Anti-Mouse, Anti-Rat, Anti-Human clone Polyclonal, Isotype Rabbit Ig, 50 µl Consult technical datasheet for details....
Rabbit polyclonal antibody to NCOA2 [Agarose Immobilized]...
Monocarboxylate (lactate) transporter 2...
Mouse Anti-Human Kallikrein 2 (Hk2)...
Biology Products: