Navigation Links
Therapeutic Cells Derived From Reprogrammed (iPS) Stem Cells Display Early Aging
Date:2/10/2010

he study. "Fortunately, we think the problem may be related to the use of viruses.  Preliminary results suggest that these abnormalities are significantly reduced using stem cells generated without the use of viruses or genetic manipulation.  Although there is excitement that iPS cells can serve as an embryo-free source of stem cells, it would premature to abandon research using embryonic stem cells until we fully understand what's causing these problems."    

Rapid progress is being made towards controlled differentiation of human iPS cells into specific tissue types, such as heart, liver, and eye including retinal pigment epithelium (RPE).  Although these studies clearly suggest a similar differentiation potential between iPS and embryonic stem cells, it is unclear whether they can be expanded into homogeneous cell populations suitable for use in drug discovery and clinical translation.  

"A major hallmark of ES-derived cells is the high recovery and proliferative capability of the cells," stated Shi-Jiang Lu, Ph.D., Senior Director of Stem International and co-senior author of the paper. "We compared the characteristics of cells derived from iPS and ES cells, and found that blood and vascular derivatives from iPS cells display abnormal molecular and/or cellular processes compared to their corresponding ESC counterparts. Similarly, RPE cells derived from iPS cells began senescing in the first passage, indicating the observed phenomenon is not limited to hemangioblastic lineages."

"More research is clearly needed before we can advance iPS cell technology into the clinic," stated William M. Caldwell, CEO and Chairman of ACTC.  "However, until this technology is perfected, we believe embryonic stem cells will play an important role in helping patients suffering from a range of debilitating diseases."  

The research
'/>"/>

SOURCE Advanced Cell Technology, Inc.
Copyright©2010 PR Newswire.
All rights reserved

Page: 1 2 3 4

Related biology technology :

1. United Therapeutics Corporation to Announce Fourth Quarter and Annual 2009 Financial Results Before Market Open on Tuesday, February 16, 2010
2. Corgenix and Tulane Announce Award of Additional NIH Contract to Expand Lassa Fever Research Towards Development of Vaccines and Improved Therapeutic Agents
3. Amicus Therapeutics Board of Directors Names Chief Executive Officer John F. Crowley Chairman of the Board
4. Silence Therapeutics to Present at 12th Annual BIO CEO & Investor Conference
5. Aegera Therapeutics Initiates a Randomized Phase 2 Study with AEG35156 for the Treatment of Hepatocellular Carcinoma
6. Oxygen Biotherapeutics, Inc. Outlines Plans for New Products During Investor Conference Presentation
7. The Honorable Tommy G. Thompson Joins the United Therapeutics Corporation Board of Directors
8. Cell Therapeutics Commits to PhRMAs Code on Interactions With Healthcare Professionals
9. WellGen, Inc. and RFI Ingredients to Collaborate on Therapeutic Nutrition Opportunities
10. Reportlinker Adds The Future of Orphan Diseases Therapeutics - Market Forecasts to 2015, Pipeline Analysis and Reimbursement
11. Dennis Winger Joins Nektar Therapeutics Board of Directors
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:8/28/2014)... an electronic which is not only based on ... spin and the spin-related magnetism. Spin-charge converters enable ... vice versa. Recently, the research group of Professor ... Johannes Gutenberg University Mainz in collaboration with researchers ... the first time realised a new, efficient spin-charge ...
(Date:8/28/2014)... Aug. 28, 2014   SunTrust Robinson Humphrey ... veterans to its equity research team in biotechnology ... expansion in equity research demonstrates our commitment to ... to enhance their investment decision making," said ... "We continue to make significant investments in differentiated ...
(Date:8/28/2014)... Washington, USA (PRWEB) August 27, 2014 ... next month for SPIE Laser Damage 2014 ... optical materials for high-power lasers will run 14-17 September. ... society for optics and photonics . , The premier ... for understanding laser damage to optical materials will engage ...
(Date:8/28/2014)... San Diego, CA (PRWEB) August 28, 2014 ... products, Pipette.com is offering a promotion for ... enables Pipette.com customers to purchase the highest quality ... Centrifuge Tubes are ideal for customers doing chemical, ... benefit lab technicians who are not regularly able ...
Breaking Biology Technology:A new, tunable device for spintronics 2A new, tunable device for spintronics 3SunTrust Robinson Humphrey Expands Equity Research in Healthcare and Energy 2SunTrust Robinson Humphrey Expands Equity Research in Healthcare and Energy 3Laser Damage to Draw Researchers, Engineers, Scientists to 46th Annual Conference 2Laser Damage to Draw Researchers, Engineers, Scientists to 46th Annual Conference 3Eppendorf Safe Lock Centrifuge Tube Promotion Now Available at Major Pipette Distributor Pipette.com 2Eppendorf Safe Lock Centrifuge Tube Promotion Now Available at Major Pipette Distributor Pipette.com 3
... Company to Make Key Marketing Claims, HARBIN, ... Inc. (the "Company") (OTC Bulletin Board: CKGT), a,vertically ... of cactus-based consumer products in China, announced today ... the Company,s Cactus,Cattle Feed. The studies, which included ...
... after an individual becomes infected with HIV the virus ... central nervous system [CNS]). Although this causes no immediate ... dementia and encephalitis (acute inflammation of the brain that ... HIV (SIV) also sometimes develop CNS damage and provide ...
... SAN FRANCISCO, Calif., June 3 Sunesis,Pharmaceuticals, Inc. ... of its,late-stage development leadership team with the appointment ... Vice President, Research and,Development and Mary G. Bolton, ... Judith A. Fox, Ph.D., has been promoted to ...
Cached Biology Technology:China Kangtai Cactus Biotech Announces Improved Milk Production in Cows From Company's Cactus Cattle Feed 2China Kangtai Cactus Biotech Announces Improved Milk Production in Cows From Company's Cactus Cattle Feed 3Sunesis Pharmaceuticals Expands Development Leadership Team to Focus on Late-Stage Development of Voreloxin (Formerly SNS-595) 2Sunesis Pharmaceuticals Expands Development Leadership Team to Focus on Late-Stage Development of Voreloxin (Formerly SNS-595) 3Sunesis Pharmaceuticals Expands Development Leadership Team to Focus on Late-Stage Development of Voreloxin (Formerly SNS-595) 4Sunesis Pharmaceuticals Expands Development Leadership Team to Focus on Late-Stage Development of Voreloxin (Formerly SNS-595) 5Sunesis Pharmaceuticals Expands Development Leadership Team to Focus on Late-Stage Development of Voreloxin (Formerly SNS-595) 6
(Date:8/28/2014)... news release is available in German . ... water fish, owes its name to a striking pattern of ... types, black cells, reflective silvery cells, and yellow cells emerge ... and arrange as a multilayered mosaic to compose the characteristic ... three cell types have to interact to form proper stripes, ...
(Date:8/28/2014)... MD FASEB MARC (Maximizing Access to Research ... for the Genetics Society of America,s 27th Annual ... October 3, 2014 in Pacific Grove, California. ... of students, post doctorates and scientists from underrepresented ... community and to encourage the participation of young ...
(Date:8/28/2014)... Bethesda, MD FASEB MARC (Maximizing Access to ... recipients for the American College of Sports Medicine,s ... 17-20, 2014 in Miami, Florida. These awards ... post doctorates and scientists from underrepresented groups into ... to encourage the participation of young scientists at ...
Breaking Biology News(10 mins):How the zebrafish gets its stripes 2How the zebrafish gets its stripes 3
... mulch offers a range of benefits and has become ... horticultural crops. Despite the recognized benefits, the plastic mulches ... be used for only one cropping season, after which ... and time-consuming processes for growers. The challenges and costs ...
... cities: safety, ready availability of infrastructure, plenty of company ... for the benefits of country life, such as clean ... and particularly birds, face the same choice between living ... avoiding disadvantages of larger colonies such as the increased ...
... stage medical device company founded by students at The ... at the Texas Life Science Forum as one of ... having the best business opportunity and promise for high ... competed in the event on Thursday, February 20 in ...
Cached Biology News:Study finds 2 biodegradable mulches to be suitable polyethylene alternatives 2The importance of (experimental) design 2The importance of (experimental) design 3Leto Solutions honored as 1 of top 10 best companies at 2014 Texas Life Science Forum 2Leto Solutions honored as 1 of top 10 best companies at 2014 Texas Life Science Forum 3
Rabbit polyclonal to Shigella Immunogen: Mixture of S. boydii, S. flexneri & S. dysenteriae....
... Antibody is a mouse monoclonal antibody ... 26 kDa glutathione-S-transferase (GST) domain from ... is suitable for detecting fusion proteins ... E. coli , yeast, mammalian, and ...
... LNA microarray slides for microRNA expression ... incorporate Exiqons unique Locked Nucleic Acid (LNA) ... mismatch discrimination for short microRNA (miRNA) targets. ... 1 g total RNA (no need for ...
... Although there have been many modifications to ... defined media, salt solutions still play an important ... to maintain the pH and osmotic balance in ... water and essential inorganic ions, is as valuable ...
Biology Products: