Navigation Links
The BBVA Foundation Frontiers of Knowledge Award goes to Coleman and Friedman, discoverers of the appetite hormone
Date:1/29/2013

intain a certain body weight," explains Friedman. The way the system works is that the more fat you have, the more leptin your body makes and the less hungry you feel. The ultimate goal is to shut down the appetite of individuals with a lot of fat, so they eat less and stop gaining weight. And vice versa. If you lose weight, your body produces less leptin and your appetite increases. The fact that the body possesses this mechanism has an evolutionary origin: "It would be very dangerous to have no fat, because you would risk dying of starvation, but it would also be dangerous to be too fat, because you would be at the mercy of predators. So the system tries to maintain an optimal level."

The lab also discovered that leptin "circulates in the blood and acts on centers in the brain to regulate appetite, just as Coleman predicted," adds Friedman, an admirer of his colleague's work: "His observations were very non-obvious. There were probably thousands of scientists looking at the same problem, but he was the one who got it right."

The discovery of leptin opened up a whole new field of research into the causes of obesity, propelled by a radical change of mentality in society and science: "Before people thought that how much we ate was completely a matter of willpower," Friedman reflects, "but we now know that body weight, in humans and other animals, is regulated by cells in the brain that receive important signals such as leptin and then unconsciously regulate appetite. And this system is absolutely crucial for the survival of any species."

This means, ultimately, that obesity is "in the mind": "As well as leptin and the leptin receptor, we know that 10 percent of morbidly obese individuals carry defects in genes that regulate food intake, metabolism and body weight. And all these genes act on the brain, which tells us that the main reason people get fat is an alteration of their brain chemistry."

Leptin, in other words, is not the only g
'/>"/>

SOURCE BBVA Foundation
Copyright©2012 PR Newswire.
All rights reserved

Page: 1 2 3 4 5 6 7 8 9

Related biology technology :

1. BBVA Foundation Unites the Efforts of Massachusetts General Hospital and Barcelonas Vall dHebron Hospital in Biomarker Research for Personalized Cancer Therapies
2. Leaders in Science Join Upcoming Celebration of the 100th Anniversary of the Oldest Science Foundation in America
3. Silence Therapeutics Announces Positive Response by USPTO that Affirms Validity of Four Foundational RNAi Patents
4. Cord Blood America Announces Exclusive Agreement With National Childrens Leukemia Foundation to Store Stem Cells
5. Elsevier Foundation Awards 2011 Grants to Advance Women in Science and Support Libraries in Developing Countries
6. Galien Foundation Announces 2012 Awards Program For Best Biopharmaceutical Products and Best Medical Technology
7. Foundation for Angelman Syndrome Therapeutics (FAST) Funds Human Clinical Trial
8. NeuroPhage Receives Michael J. Fox Foundation Funding for Parkinsons Disease Research
9. Foundation of UMDNJ Receives Grand Challenges Tuberculosis Biomarkers Grant
10. Foundation for Health Improvement and Technology (FHIT) Launched to Beat Cardiovascular Disease
11. Systems Alliance Launches Redesigned Website for The Living Legacy Foundation of Maryland
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:4/23/2015)... CA (PRWEB) April 23, 2015 ... leader in Personalized Medicine, is excited to announce ... Response profile . This profile assesses 62 genetic ... provide dosing information for commonly prescribed non-opioid pain ... (brand name Neurontin), alprazolam (brand name Xanax) and ...
(Date:4/23/2015)... , April 23, 2015  Propanc Health ... healthcare company, focuses on the development of cancer ... The company lead product includes PRP, a patented ... and chymotrypsinogen, as well as the enzyme amylase ... also developing a combination of anti-cancer agents working ...
(Date:4/23/2015)... 2015 ReliantHeart's HeartAssist5® Ventricular Assist Device ... through the device) in real time, and this data ... leading provider of Machine to Machine (M2M) communications for ... via VADLink.com can be monitored by a ... in flow below a minimum threshold, the patient can ...
(Date:4/22/2015)... , April 23, 2015  The Heinz Family ... th Heinz Awards, which will present unrestricted ... Americans for their creativity and determination in finding ... This year,s recipients include a prolific ... modern-day life and personal relationships; two former Marines ...
Breaking Biology Technology:Proove Biosciences Launches World’s First Test to Predict Responders to Commonly Prescribed Non-Opioid Pain Medications 2Proove Biosciences Launches World’s First Test to Predict Responders to Commonly Prescribed Non-Opioid Pain Medications 3Early Stage BioTech offers Plenty of Risk; Propanc Health Group Analyst Brief Issued by BrokerBank Securities, Inc. 2From a Scientist Who Develops Human Microlivers to a New Yorker Cartoonist Who Masterfully Depicts the Humor and Heartbreak of Everyday Life: The 20th Heinz Awards Honors Six Changemakers 2From a Scientist Who Develops Human Microlivers to a New Yorker Cartoonist Who Masterfully Depicts the Humor and Heartbreak of Everyday Life: The 20th Heinz Awards Honors Six Changemakers 3From a Scientist Who Develops Human Microlivers to a New Yorker Cartoonist Who Masterfully Depicts the Humor and Heartbreak of Everyday Life: The 20th Heinz Awards Honors Six Changemakers 4From a Scientist Who Develops Human Microlivers to a New Yorker Cartoonist Who Masterfully Depicts the Humor and Heartbreak of Everyday Life: The 20th Heinz Awards Honors Six Changemakers 5From a Scientist Who Develops Human Microlivers to a New Yorker Cartoonist Who Masterfully Depicts the Humor and Heartbreak of Everyday Life: The 20th Heinz Awards Honors Six Changemakers 6
... Inclinix, Inc. has announced today that it has ... (Nasdaq: DATA ) to offer the most ... device companies globally. , ... DATATRAK,s eClinical(TM) platform to enhance its services as a ...
... Md., April 30 /PRNewswire/ -- ... company developing novel, proprietary antibodies for the treatment of ... will host a conference call and audio webcast on ... (3:00 pm Central European Time) to discuss its financial ...
... Inc. (NASDAQ: AEZS , TSX: AEZ), a ... will announce its first quarter 2009 financial and operating ... The Company will host a conference call and webcast ... 3:30 p.m., Eastern Time. , Participants may access the ...
Cached Biology Technology:DATATRAK International, Inc. Forms Strategic Partnership with Inclinix, Inc. 2DATATRAK International, Inc. Forms Strategic Partnership with Inclinix, Inc. 3DATATRAK International, Inc. Forms Strategic Partnership with Inclinix, Inc. 4Micromet, Inc. to Host Conference Call and Webcast to Report First Quarter 2009 Financial Results on May 6, 2009 2Micromet, Inc. to Host Conference Call and Webcast to Report First Quarter 2009 Financial Results on May 6, 2009 3Micromet, Inc. to Host Conference Call and Webcast to Report First Quarter 2009 Financial Results on May 6, 2009 4
(Date:4/10/2015)... , April 10, 2015 Research ... of the "Security Competitive Profiles - NEC" ... , NEC will continue to supply a ... the market, with a company focus on the development ... Winning opportunities in the Asia-Pacific ...
(Date:4/2/2015)... April 2, 2015 At its 2015 ACMG ... City , the American College of Medical Genetics ... directors to its Board.  Members of the ACMG Board ... for forming and advancing its policies and programs. ACMG ... "It,s an eventful time in medical genetics ...
(Date:3/31/2015)... YORK , March 31, 2015  Elephant Talk ... "Company"), a global provider of Software Defined Network Architecture ... today announced total revenue of approximately $20.4 million for ... a restated $19.5 million for the year ended December ... calendar 2014, the Company had completed its multi-year transition ...
Breaking Biology News(10 mins):NEC Security Competitive Profile 2015 2American College of Medical Genetics and Genomics Announces New Board Members: Dr. Louanne Hudgins is ACMG President-Elect 2American College of Medical Genetics and Genomics Announces New Board Members: Dr. Louanne Hudgins is ACMG President-Elect 3American College of Medical Genetics and Genomics Announces New Board Members: Dr. Louanne Hudgins is ACMG President-Elect 4American College of Medical Genetics and Genomics Announces New Board Members: Dr. Louanne Hudgins is ACMG President-Elect 5American College of Medical Genetics and Genomics Announces New Board Members: Dr. Louanne Hudgins is ACMG President-Elect 6American College of Medical Genetics and Genomics Announces New Board Members: Dr. Louanne Hudgins is ACMG President-Elect 7American College of Medical Genetics and Genomics Announces New Board Members: Dr. Louanne Hudgins is ACMG President-Elect 8Elephant Talk Reports 2014 Fourth Quarter and Year End Financial Results 2Elephant Talk Reports 2014 Fourth Quarter and Year End Financial Results 3Elephant Talk Reports 2014 Fourth Quarter and Year End Financial Results 4Elephant Talk Reports 2014 Fourth Quarter and Year End Financial Results 5Elephant Talk Reports 2014 Fourth Quarter and Year End Financial Results 6
... fourth largest honey producer and fifth largest honey exporter ... rural farmers in Mexico to quantify the genetically modified ... sale in Germany. Their results will appear Feb. 7 ... Roubik, senior staff scientist at the Smithsonian Tropical Research ...
... top predators to walk on land were not afraid to ... Toronto Mississauga study has found. Graduate student and lead ... of T Mississauga,s Department of Biology suggest that Dimetrodon ... and 272 million years ago, was the first terrestrial vertebrate ...
... (U.S.) predominance in science and technology (S&T) eroded further ... and South Korea--rapidly increased their innovation capacities. According to ... (NSB), the policy making body of the National Science ... Congress, the major Asian economies, taken together, now perform ...
Cached Biology News:Smithsonian reports GMO soybean pollen threatens Mexican honey sales 2'Steak-knife' teeth reveal ecology of oldest land predators 2US lead in science and technology shrinking 2US lead in science and technology shrinking 3US lead in science and technology shrinking 4
G-protein coupled purinergic receptor P2Y8...
This application changes sensitive keywords in an FCS file to remove patient information. It was contributed by Dr. David Miller....
Recognizes rat Taste Receptor 2 (TR2). The immunogen shows no significant sequence homology with TR1, gustducin or other pheromone receptors....
Rat monoclonal [HK5.3] to B7 RP1 (Biotin) ( Abpromise for all tested applications). entrezGeneID: 23308 SwissProtID: O75144...
Biology Products: