Navigation Links
The BBVA Foundation Frontiers of Knowledge Award goes to Coleman and Friedman, discoverers of the appetite hormone
Date:1/29/2013

intain a certain body weight," explains Friedman. The way the system works is that the more fat you have, the more leptin your body makes and the less hungry you feel. The ultimate goal is to shut down the appetite of individuals with a lot of fat, so they eat less and stop gaining weight. And vice versa. If you lose weight, your body produces less leptin and your appetite increases. The fact that the body possesses this mechanism has an evolutionary origin: "It would be very dangerous to have no fat, because you would risk dying of starvation, but it would also be dangerous to be too fat, because you would be at the mercy of predators. So the system tries to maintain an optimal level."

The lab also discovered that leptin "circulates in the blood and acts on centers in the brain to regulate appetite, just as Coleman predicted," adds Friedman, an admirer of his colleague's work: "His observations were very non-obvious. There were probably thousands of scientists looking at the same problem, but he was the one who got it right."

The discovery of leptin opened up a whole new field of research into the causes of obesity, propelled by a radical change of mentality in society and science: "Before people thought that how much we ate was completely a matter of willpower," Friedman reflects, "but we now know that body weight, in humans and other animals, is regulated by cells in the brain that receive important signals such as leptin and then unconsciously regulate appetite. And this system is absolutely crucial for the survival of any species."

This means, ultimately, that obesity is "in the mind": "As well as leptin and the leptin receptor, we know that 10 percent of morbidly obese individuals carry defects in genes that regulate food intake, metabolism and body weight. And all these genes act on the brain, which tells us that the main reason people get fat is an alteration of their brain chemistry."

Leptin, in other words, is not the only g
'/>"/>

SOURCE BBVA Foundation
Copyright©2012 PR Newswire.
All rights reserved

Page: 1 2 3 4 5 6 7 8 9

Related biology technology :

1. BBVA Foundation Unites the Efforts of Massachusetts General Hospital and Barcelonas Vall dHebron Hospital in Biomarker Research for Personalized Cancer Therapies
2. Leaders in Science Join Upcoming Celebration of the 100th Anniversary of the Oldest Science Foundation in America
3. Silence Therapeutics Announces Positive Response by USPTO that Affirms Validity of Four Foundational RNAi Patents
4. Cord Blood America Announces Exclusive Agreement With National Childrens Leukemia Foundation to Store Stem Cells
5. Elsevier Foundation Awards 2011 Grants to Advance Women in Science and Support Libraries in Developing Countries
6. Galien Foundation Announces 2012 Awards Program For Best Biopharmaceutical Products and Best Medical Technology
7. Foundation for Angelman Syndrome Therapeutics (FAST) Funds Human Clinical Trial
8. NeuroPhage Receives Michael J. Fox Foundation Funding for Parkinsons Disease Research
9. Foundation of UMDNJ Receives Grand Challenges Tuberculosis Biomarkers Grant
10. Foundation for Health Improvement and Technology (FHIT) Launched to Beat Cardiovascular Disease
11. Systems Alliance Launches Redesigned Website for The Living Legacy Foundation of Maryland
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/24/2014)... to materialise. Yet, scientists are making progress in ... One such approach relies on quantum dotsa kind ... electric field. A new study demonstrates that changing ... (TQDs) with electrical impulses can help better control ... be used as quantum information units, which would ...
(Date:7/24/2014)... Research and Markets has announced ... Analytical Instruments Market 2014-2018" report to their offering. ... Genomics is the study of the gene and its ... and functions of proteomes or sets of proteins by ... involves the mapping of genes and DNA sequencing to ...
(Date:7/24/2014)... 24, 2014 Three companies from the ... Livestrong’s Big C Competition. Out of 700 competition entrants, ... to the semi-final round. In this round twenty teams ... program, complete with mentoring from thought-leaders and medical entrepreneurs ... of the angelMD commitment to the Livestrong vision around ...
(Date:7/24/2014)... July 24, 2014 1000 balances – ... input on customers’ weighing needs and expertly narrows down ... of balances, scales or even terminals. , First, ... smallest weight (or select readability instead) and define the ... additional selection criteria narrows down the list to models ...
Breaking Biology Technology:Global Genomics and Proteomics Analytical Instruments Market 2014-2018: Key Vendors are Agilent, Bio-Rad , F. Hoffmann, La Roche, Illumina, PerkinElmer and Thermo Fisher Scientific 23 angelMD Startups Make Livestrong Big C Semi-finals 2
... knowingly misrepresented the ... company to ... filed a,proposed class-action lawsuit on behalf of CellCyte Genetics Corporation,(OTC ... and chief executive officer Gary A.,Reys, background, causing company stocks ...
... SAN DIEGO, Jan. 18 The San Diego ... has received the,highest score in three of four ... on Part I of the Major Facilities Grant,Application., ... earned scores of,99 for basic research and discovery, ...
... objects to implications in a New York Times article ... clinical,trials., The story, based on a separate article ... and Lilly as high-profile examples of how the,industry purportedly ... story inaccurate when it comes to Prozac -- the ...
Cached Biology Technology:Hagens Berman Sobol Shapiro: Lawsuit Filed Against CellCyte Genetics Corporation 2Hagens Berman Sobol Shapiro: Lawsuit Filed Against CellCyte Genetics Corporation 3SDCRM Receives Highest Score in Three of Four Categories from CIRM on Part I of Major Facilities Grant Application 2SDCRM Receives Highest Score in Three of Four Categories from CIRM on Part I of Major Facilities Grant Application 3In response to a New England Journal of Medicine article published yesterday and subsequent media coverage, Eli Lilly and Company issued the following statement: 2In response to a New England Journal of Medicine article published yesterday and subsequent media coverage, Eli Lilly and Company issued the following statement: 3In response to a New England Journal of Medicine article published yesterday and subsequent media coverage, Eli Lilly and Company issued the following statement: 4
(Date:7/25/2014)... New research at the University of Adelaide has opened the ... resistance to powdery mildew. , In Australia, annual barley production ... year. Powdery mildew is one of the most important diseases ... team have discovered the composition of special growths on the ... the fungus into the leaf. , The research, by the ...
(Date:7/25/2014)... central nervous system disease that is caused by ... the embryonic phase. Many patients have varying degrees ... retardation. Such problems decrease the patients, functional independence ... Physical Medicine and Rehabilitation Education and Research Hospital, ... SB, using the Pediatric Evaluation of Disability Inventory ...
(Date:7/25/2014)... that the age girls reach puberty is influenced by ,imprinted ... parent contributes the gene. This is the first evidence ... birth and details of this study were published today in ... period, known as menarche, is a marker for the timing ... onset of menses varies between girls, is an inherited trait, ...
Breaking Biology News(10 mins):New hope for powdery mildew resistant barley 2Could age of first period influence development of diseases in older women? 2
... provide key insights for scientists and medical researchers, but ... pose some key challenges. Researchers at North Carolina ... the parameters used in such models which may ... fertility. "These oscillatory systems are found in everything ...
... facility in the US, researchers at the University of Gothenburg have ... is to film how proteins work at molecular level. ... cells could be the key to cures for everything from cancer ... University of Gothenburg, and his research group were among the first ...
... Carrying a gun in bear country doesn,t mean you,re more protected ... out of Brigham Young University. A study led by BYU ... gun is no more effective in keeping people from injury or ... really isn,t about the kind of gun you carry, it,s about ...
Cached Biology News:New method for estimating parameters may boost biological models 2New method for estimating parameters may boost biological models 3More effective method of imaging proteins 2BYU study: Using a gun in bear encounters doesn't make you safer 2
... Versatile, modular, computer controlled pre-amplifier suitable for ... isolated electrode input for recording physiological signal ... and a transducer input for use with ... transducers. Additional options include a stimulus artefact ...
... Polystyrene covers can be used ... Ridged covers for stacking of ... covers for use with automated ... ridged and non-ridged, are available ...
... available for use with 96- or 384-well PCR plates ... ease of location on 96-tube plates End tabs ... of the plate* Efficient sealing is achieved with ... with screw or clip-down hot lid thermal cyclers ...
... be used with all 96-well ... stacking of covered plates ... with automated systems ... are available for use with ...
Biology Products: