Navigation Links
Tenfold boost in ability to pinpoint proteins in cancer cells
Date:3/19/2013

Better diagnosis and treatment of cancer could hinge on the ability to better understand a single cell at its molecular level. New research offers a more comprehensive way of analyzing one cell's unique behavior, using an array of colors to show patterns that could indicate why a cell will or won't become cancerous.

A University of Washington team has developed a new method for color-coding cells that allows them to illuminate 100 biomarkers, a ten-time increase from the current research standard, to help analyze individual cells from cultures or tissue biopsies. The work is published this week (March 19) in Nature Communications.

"Discovering this process is an unprecedented breakthrough for the field," said corresponding author Xiaohu Gao, a UW associate professor of bioengineering. "This technology opens up exciting opportunities for single-cell analysis and clinical diagnosis."

The research builds on current methods that use a smaller array of colors to point out a cell's biomarkers characteristics that indicate a special, and potentially abnormal or diseased, cell. Ideally, scientists would be able to test for a large number of biomarkers, then rely on the patterns that emerge from those tests to understand a cell's properties.

The UW research team has created a cycle process that allows scientists to test for up to 100 biomarkers in a single cell. Before, researchers could only test for 10 at a time.

The analysis uses quantum dots, which are fluorescent balls of semiconductor material. Quantum dots are the smaller version of the material found in many electronics, including smartphones and radios. These quantum dots are between 2 and 6 nanometers in diameter, and they vary on the color they emit depending on their size.

Cyclical testing hasn't been done before, though many quantum dot papers have tried to expand the number of biomarkers tested for in a single cell. This method essentially reuses the
'/>"/>

Contact: Michelle Ma
mcma@uw.edu
206-543-2580
University of Washington
Source:Eurekalert  

Page: 1 2 3

Related biology technology :

1. New semiconductor research may extend integrated circuit battery life tenfold
2. Are Pros "Cheating" with Undetectable HGH Boosters?
3. Genuine Bio-Fuel Inc. Notes Sustainable Energy Gets A Much Needed Boost from the President Obama During 2013 Inaugural Address
4. Genedata Biologics 3.0 Boosts Efficiency Through Standardization
5. Tiny structure gives big boost to solar power
6. Nature Materials study: Boosting heat transfer with nanoglue
7. Industrial carbon management research gets $3.75 million boost
8. A 300 Million Euro Boost for Biomedicine in Berlin
9. Rice team boosts silicon-based batteries
10. LLSs Lead Therapy Acceleration Program in MDS Gets Boost from Major Industry Licensing Agreement
11. Spinach power gets a big boost
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Tenfold boost in ability to pinpoint proteins in cancer cells
(Date:4/16/2015)... OSAKA, Japan , April 16, 2015 ... of Kyoto University and Takeda Pharmaceutical Company Limited ... to develop clinical applications of induced pluripotent stem ... mellitus, neurological disorders and cancer immunotherapy. The "Takeda-CiRA ... designed to expedite multiple research projects for drug ...
(Date:4/16/2015)... Francisco, CA (PRWEB) April 16, 2015 ... scheduled to report first quarter results on Thursday, April ... announcement, Cytokinetics’ senior management will host a conference call ... financial results and the company’s outlook for the future. ... can be accessed from the homepage and in the ...
(Date:4/16/2015)... (PRWEB) April 16, 2015 Proove ... Buzz of BIO Contest for the 2015 ... (BIO), the 2015 BIO International Convention will take place ... Pennsylvania. During the Buzz of BIO contest, industry leaders ... see present at the conference. The community voting period ...
(Date:4/16/2015)... 2015 Regis Technologies looks forward to ... Cancer Research (AACR) annual meeting. Regis will exhibit at ... Saturday, April 18, in Philadelphia and running through April ... of the oldest and largest organization focused on cancer ... and partners with survivors to promote awareness and research ...
Breaking Biology Technology:CiRA and Takeda Enter 10-year Collaboration on iPS Cell Research 2CiRA and Takeda Enter 10-year Collaboration on iPS Cell Research 3Cytokinetics to Announce First Quarter Results on April 30, 2015 2Cytokinetics to Announce First Quarter Results on April 30, 2015 3Proove Bisociences to Participate in the Buzz of BIO at the 2015 BIO International Convention 2Proove Bisociences to Participate in the Buzz of BIO at the 2015 BIO International Convention 3Regis Technologies Joins American Association for Cancer Research Annual Meeting 2
... A. Mirkin has mass-produced the 2008 Summer Olympics logo -- ... centimeter of space. , Mirkin and his colleagues printed ... a new printing technique, called Polymer Pen Lithography (PPL), that ... device. , The PPL technique, to be published Aug. ...
... 14 Keck Graduate Institute,(KGI) in collaboration with ... center, announced the launch of its new Certificate ... fellows. KGI has,secured funding to allow a limited ... the program with scholarships that will cover tuition., ...
... (Nasdaq: NLTX ), today announced financial results for the ... loss for the three months ended June 30, 2008 was ... $0.11 per share, for,the same period of 2007. Net operating ... million or $0.28 per share compared to $2.2 million,or $0.16 ...
Cached Biology Technology:Northwestern chemists take gold, mass-produce Beijing Olympic logo 2City of Hope Helps KGI Launch New Management Training Program for Scientists 2City of Hope Helps KGI Launch New Management Training Program for Scientists 3Nile Therapeutics, Inc. Reports 2008 Second Quarter Financial Results 2Nile Therapeutics, Inc. Reports 2008 Second Quarter Financial Results 3Nile Therapeutics, Inc. Reports 2008 Second Quarter Financial Results 4
(Date:3/26/2015)... , March 26, 2015 ... family, social, recreation and athletic club, today announced it ... to allow freedom of movement for members and staff, ... "Following a comprehensive process, we selected FST,s IMID Access ... and convenience for our members and staff, in addition ...
(Date:3/24/2015)... , March 24, 2015   NexID Biometrics ... with critical security-authentication needs, today announced the beginning of ... (FFD) solution. The company, based in ... at the three-day Connect:ID Expo, which began here today ... NexID said version 2.0 of its SDK boosts the ...
(Date:3/23/2015)... 2015   HOYOS Labs , a leading global ... that the Company will demonstrate multiple biometrics-based technologies under ... at Connect:ID on March 23 through 25, 2015, in ... highlight the IEEE Biometric Open Protocol Standard; free biometrics-based ... access control system. BOPS was invented by HOYOS Labs ...
Breaking Biology News(10 mins):Granite Club First Private Club in North America to Implement FST Biometrics Secure Access Solution, as Part of Multi-million Dollar Expansion 2NexID Begins Shipments Of Version 2.0 Fake-Finger-Detection Solution 2HOYOS Labs to Showcase Host of Biometrics Technologies at Connect:ID in Washington, D.C. 2HOYOS Labs to Showcase Host of Biometrics Technologies at Connect:ID in Washington, D.C. 3
... of years ago, humans began scrubbing off and discarding ... white kernel beneath. Now, for the first time, scientists ... rice processing, called rice bran, significantly lowers blood pressure ... The team reports their findings in the March 8 ...
... gnawing its way into a carcass and staying inside to feed ... Columbia (Canada) believe the Hagfish's gruesome method of feeding may cause ... build up of CO2 produced by the fish, which could explain ... up to 7% CO2 (350 × that found in normal air). ...
... with Affymetrix, Inc., have designed a chip ?the GeneChip® ... suggest ways to better manage them. By helping determine ... citrus ?genes that are associated with taste, acidic content ... to researchers for rectifying existing problems and making improvements ...
Cached Biology News:How nice, brown rice: Study shows rice bran lowers blood pressure in rats 2UCR researchers design chip that can improve citrus varieties 2UCR researchers design chip that can improve citrus varieties 3