Navigation Links
Tenfold boost in ability to pinpoint proteins in cancer cells
Date:3/19/2013

Better diagnosis and treatment of cancer could hinge on the ability to better understand a single cell at its molecular level. New research offers a more comprehensive way of analyzing one cell's unique behavior, using an array of colors to show patterns that could indicate why a cell will or won't become cancerous.

A University of Washington team has developed a new method for color-coding cells that allows them to illuminate 100 biomarkers, a ten-time increase from the current research standard, to help analyze individual cells from cultures or tissue biopsies. The work is published this week (March 19) in Nature Communications.

"Discovering this process is an unprecedented breakthrough for the field," said corresponding author Xiaohu Gao, a UW associate professor of bioengineering. "This technology opens up exciting opportunities for single-cell analysis and clinical diagnosis."

The research builds on current methods that use a smaller array of colors to point out a cell's biomarkers characteristics that indicate a special, and potentially abnormal or diseased, cell. Ideally, scientists would be able to test for a large number of biomarkers, then rely on the patterns that emerge from those tests to understand a cell's properties.

The UW research team has created a cycle process that allows scientists to test for up to 100 biomarkers in a single cell. Before, researchers could only test for 10 at a time.

The analysis uses quantum dots, which are fluorescent balls of semiconductor material. Quantum dots are the smaller version of the material found in many electronics, including smartphones and radios. These quantum dots are between 2 and 6 nanometers in diameter, and they vary on the color they emit depending on their size.

Cyclical testing hasn't been done before, though many quantum dot papers have tried to expand the number of biomarkers tested for in a single cell. This method essentially reuses the
'/>"/>

Contact: Michelle Ma
mcma@uw.edu
206-543-2580
University of Washington
Source:Eurekalert  

Page: 1 2 3

Related biology technology :

1. New semiconductor research may extend integrated circuit battery life tenfold
2. Are Pros "Cheating" with Undetectable HGH Boosters?
3. Genuine Bio-Fuel Inc. Notes Sustainable Energy Gets A Much Needed Boost from the President Obama During 2013 Inaugural Address
4. Genedata Biologics 3.0 Boosts Efficiency Through Standardization
5. Tiny structure gives big boost to solar power
6. Nature Materials study: Boosting heat transfer with nanoglue
7. Industrial carbon management research gets $3.75 million boost
8. A 300 Million Euro Boost for Biomedicine in Berlin
9. Rice team boosts silicon-based batteries
10. LLSs Lead Therapy Acceleration Program in MDS Gets Boost from Major Industry Licensing Agreement
11. Spinach power gets a big boost
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Tenfold boost in ability to pinpoint proteins in cancer cells
(Date:7/22/2014)... Angeles, CA (PRWEB) July 22, 2014 ... test solutions with the debut of its fluorescent ... of Clinical Chemistry (AACC) meeting in Chicago, July ... or bench top versions, the HRDR-300 is a ... pending technology to analyze fluorescent lateral flow immunoassays ...
(Date:7/21/2014)... July 21, 2014 Lawrence ... Investment Board (WIB) and Las Positas College (LPC) ... technical education and hands-on training for veterans, officials ... Program at Las Positas is designed to ... for engineering technician careers, and establishes a pipeline ...
(Date:7/21/2014)... PHILADELPHIA , July 21, 2014  Mike ... closing of $1.6 million in Series Seed B ... and chemical sensors for the life science, defense, ... Trimaran Capital Partners led the round and was ... 36 Angels.  Said Patterson , "This round ...
(Date:7/19/2014)... 20, 2014 United States Non-Vascular ... GlobalDatas new report, "United States Non-Vascular Stents Market ... the United States Non-Vascular Stents market. The report ... (in units) and average prices (in US dollars) ... Stents and Metal Biliary Stents (Metal Non-Covered Biliary ...
Breaking Biology Technology:Holomic to Debut HRDR-300 Fluorescent Immunoassay Reader at the AACC 2014 2Engineering Program Established for Veterans 2Engineering Program Established for Veterans 3Global Graphene Manufacturing Leader, Graphene Frontiers, Receives Series Seed B Funding To Assure Production Of The Next Generation Of Biological And Chemical Sensor Technology 2United States Non-Vascular Stents Market Outlook to 2020 | Researchmoz 2United States Non-Vascular Stents Market Outlook to 2020 | Researchmoz 3United States Non-Vascular Stents Market Outlook to 2020 | Researchmoz 4
... Quarter of 2007 -, - Tests Delivered Grew 68 Percent ... - Conference Call ... Genomic Health,Inc. (Nasdaq: GHDX ) today reported financial results and ... to $23.4 million in the first quarter of 2008,compared to $14.1 million ...
... CHAPEL HILL, N.C., May 6 There are a ... successful re-launch. An organization,s,sales force must be involved with ... crucial to any successful re-launch effort,according to a study ... you invigorate a sales force? Half of the companies ...
... ExonHit Therapeutics S.A.,(Alternext: ALEHT), a drug and ... its new SpliceArray(TM) for use in disease,modeling ... pre-clinical,research communities. These SpliceArray(TM) products provide the ... genome commercially,available today. ExonHit,s patented unique approach ...
Cached Biology Technology:Genomic Health Announces First Quarter 2008 Financial Results and Business Progress 2Genomic Health Announces First Quarter 2008 Financial Results and Business Progress 3Genomic Health Announces First Quarter 2008 Financial Results and Business Progress 4Genomic Health Announces First Quarter 2008 Financial Results and Business Progress 5Genomic Health Announces First Quarter 2008 Financial Results and Business Progress 6Genomic Health Announces First Quarter 2008 Financial Results and Business Progress 7Genomic Health Announces First Quarter 2008 Financial Results and Business Progress 8Genomic Health Announces First Quarter 2008 Financial Results and Business Progress 9Invigorated Sales Force Key to a Successful Re-Launch 2ExonHit Launches Rat Genome SpliceArray(TM) Products to Expand High Resolution Gene Expression Profiling for use in Disease Modeling and Toxicogenomics 2ExonHit Launches Rat Genome SpliceArray(TM) Products to Expand High Resolution Gene Expression Profiling for use in Disease Modeling and Toxicogenomics 3
(Date:7/21/2014)... A University of California, San Diego School of Medicine-led ... not recognize the potentially serious health consequences of childhood ... in helping their child reach a healthy weight. , ... of the Academy of Nutrition and Dietetics . , ... and physical activity behaviors," said lead author Kyung Rhee, ...
(Date:7/21/2014)... cheating in science are among the topics to ... experts in Montreal at the three International Union ... to August 1, 2014. Some 2,000 participants from ... 14th International Congress of Bacteriology and Applied Microbiology, ... Microbiology, and the 16th International Congress of Virology. ...
(Date:7/21/2014)... 154 hotspots in areas across Riau province on Sunday, ... again following a decline in rainfall. The number ... than what had been reported one day prior, which ... scattered in six regencies and municipalities, most of which ... related haze it creates could potentially spread via winds ...
Breaking Biology News(10 mins):Parents rank their obese children as 'very healthy' 2Montreal hosts International Union of Microbiology Societies congresses 2
... Howard Hughes Medical Institute investigator Brian J. Druker and ... unknown genetic mutations that can trigger cancerous growth. By ... myeloid leukemia (AML) cells, the researchers have dramatically reduced ... abnormalities that might be vulnerable to specific drug treatments. ...
... shows the need for an international moratorium on bottom-trawling ... life, Conservation International (CI) said. , The U.N. Division ... reviewed measures to protect the vulnerable deep oceans of ... lies beyond the national jurisdictions of any individual nation. ...
... that it allows scientists peering inside cells to ... protein they are studying has been developed and ... Medical Institute's Janelia Farm Research Campus in collaboration ... and Florida State University. , The new technique ...
Cached Biology News:New strategy rapidly identifies cancer targets 2New strategy rapidly identifies cancer targets 3UN review shows need to halt destructive fishing practice 2New light microscope sharpens scientists' focus 2New light microscope sharpens scientists' focus 3New light microscope sharpens scientists' focus 4New light microscope sharpens scientists' focus 5New light microscope sharpens scientists' focus 6
Request Info...
Recombinant Equine TNF-alpha/TNFSF1A, CF...
Recombinant Equine IL-4, CF...
actin from rabbit muscle Cell Biology Cytoskeletal Probes Actin and Actin Probes...
Biology Products: