Navigation Links
Tenfold boost in ability to pinpoint proteins in cancer cells
Date:3/19/2013

Better diagnosis and treatment of cancer could hinge on the ability to better understand a single cell at its molecular level. New research offers a more comprehensive way of analyzing one cell's unique behavior, using an array of colors to show patterns that could indicate why a cell will or won't become cancerous.

A University of Washington team has developed a new method for color-coding cells that allows them to illuminate 100 biomarkers, a ten-time increase from the current research standard, to help analyze individual cells from cultures or tissue biopsies. The work is published this week (March 19) in Nature Communications.

"Discovering this process is an unprecedented breakthrough for the field," said corresponding author Xiaohu Gao, a UW associate professor of bioengineering. "This technology opens up exciting opportunities for single-cell analysis and clinical diagnosis."

The research builds on current methods that use a smaller array of colors to point out a cell's biomarkers characteristics that indicate a special, and potentially abnormal or diseased, cell. Ideally, scientists would be able to test for a large number of biomarkers, then rely on the patterns that emerge from those tests to understand a cell's properties.

The UW research team has created a cycle process that allows scientists to test for up to 100 biomarkers in a single cell. Before, researchers could only test for 10 at a time.

The analysis uses quantum dots, which are fluorescent balls of semiconductor material. Quantum dots are the smaller version of the material found in many electronics, including smartphones and radios. These quantum dots are between 2 and 6 nanometers in diameter, and they vary on the color they emit depending on their size.

Cyclical testing hasn't been done before, though many quantum dot papers have tried to expand the number of biomarkers tested for in a single cell. This method essentially reuses the
'/>"/>

Contact: Michelle Ma
mcma@uw.edu
206-543-2580
University of Washington
Source:Eurekalert  

Page: 1 2 3

Related biology technology :

1. New semiconductor research may extend integrated circuit battery life tenfold
2. Are Pros "Cheating" with Undetectable HGH Boosters?
3. Genuine Bio-Fuel Inc. Notes Sustainable Energy Gets A Much Needed Boost from the President Obama During 2013 Inaugural Address
4. Genedata Biologics 3.0 Boosts Efficiency Through Standardization
5. Tiny structure gives big boost to solar power
6. Nature Materials study: Boosting heat transfer with nanoglue
7. Industrial carbon management research gets $3.75 million boost
8. A 300 Million Euro Boost for Biomedicine in Berlin
9. Rice team boosts silicon-based batteries
10. LLSs Lead Therapy Acceleration Program in MDS Gets Boost from Major Industry Licensing Agreement
11. Spinach power gets a big boost
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Tenfold boost in ability to pinpoint proteins in cancer cells
(Date:5/22/2015)... (PRWEB) May 22, 2015 Knowledgent ... white paper that explores the potential of big data ... white paper was developed to help life sciences and ... leverage data to gain critical business insights. , The ... amounts of data driven by patient profiling, compliance and ...
(Date:5/21/2015)... , May 21, 2015  Susan Hedstrom, ... (FPWR), a nonprofit organization dedicated to supporting research ... syndrome (PWS), announced today that FPWR has received ... Irina Shaulov contributed $1 million in ... initiatives.  "Our ...
(Date:5/21/2015)... May 21, 2015 W. R. ... manufacturing facility in Worms, Germany has received good ... subsidiary of the International Pharmaceutical Excipient Council (IPEC) ... that produce its SYLOID® FP brand of pharmaceutical ... certification, following the Curtis Bay, Maryland (USA) and ...
(Date:5/21/2015)... May 21, 2015 /PRNewswire/ - RepliCel Life Sciences ... regenerative medicine company focused on the development of ... presentation at the International Society for Cellular Therapy ... Achilles tendinosis currently in a Phase 1/2 clinical ... th from 5:30 PM to 7:00 PM ...
Breaking Biology Technology:New White Paper Explores the Potential of Big Data Analytics in Life Sciences and Healthcare 2The Foundation for Prader-Willi Research Receives $1M Contribution in Support of Clinical Initiatives 2Grace European Facility Receives GMP Excipient Certification for SYLOID® FP Silica Gel 2RepliCel to Present Unique Autologous Cell Treatment for Achilles Tendinosis at International Society for Cellular Therapy Conference 2RepliCel to Present Unique Autologous Cell Treatment for Achilles Tendinosis at International Society for Cellular Therapy Conference 3
... , COLLEGEVILLE, Pa., Aug. 11 ... WYE ), announced it received notice that the action date for ... Biologics License Application (BLA) for Prevnar ... from September 30, 2009, to December 30, 2009. In response ...
... , , WILMINGTON, Del., Aug. 11 ... appropriate use of drugs, is sponsoring a free Webinar-on-Demand created ... as a role of chief safety officers in healthcare companies. ... at ParagonRx,s website, www.para g onrx.com/experience/webinars/ ...
... Baltimore Convention Center - September 21-23, 2009 ... This summit will attract more than 1,200 experts from more than ... than 100 speakers, including governors, federal officials, and top researchers and ... and human-interest stories. This is your chance to meet and ...
Cached Biology Technology:Wyeth Provides Regulatory Update on Prevnar 13* in the United States 2Wyeth Provides Regulatory Update on Prevnar 13* in the United States 3Wyeth Provides Regulatory Update on Prevnar 13* in the United States 4Wyeth Provides Regulatory Update on Prevnar 13* in the United States 5Wyeth Provides Regulatory Update on Prevnar 13* in the United States 6World Stem Cell Summit to Be Held in Baltimore 2
(Date:5/22/2015)... May 22, 2015  NXT-ID, Inc. (NASDAQ: NXTD ) ... will be ending its promotional pricing and making the Wocket ... Laurence Savin , Head of Marketing said, "We,ve extended ... until the end of May. To get your wocket at ... we open the store on June 1, you,ll receive a ...
(Date:5/21/2015)... , May 21, 2015 ... Imaging Market by Solutions (Hardware, Software, Services), by Applications ... & others), by End-Users (Military & Defense & ... MarketsandMarkets, Thermal Imaging Market is expected to grow ... by 2020, at a Compound Annual Growth Rate ...
(Date:5/20/2015)... , May 20, 2015 ... ) has announced the addition of ... Global Iris Recognition Market"  report to ... ,This research service analyses trends in ... government and commercial sectors, globally. Despite ...
Breaking Biology News(10 mins):NXT-ID, Inc Announces Retail Price For Wocket Smart Wallet And Extends Discounted Promotional Price Till End Of May 2NXT-ID, Inc Announces Retail Price For Wocket Smart Wallet And Extends Discounted Promotional Price Till End Of May 3Thermal Imaging Market Worth $9,998.9 Million by 2020 2Thermal Imaging Market Worth $9,998.9 Million by 2020 3Thermal Imaging Market Worth $9,998.9 Million by 2020 4Global Iris Recognition Market Report 2015 - 5-Year Opportunity Analysis 2
... plant used a century ago during the great Spanish influenza ... killing the H1N1 swine flu virus that now threatens the ... but when raw it has sap so foul-smelling that some ... is scheduled for the Sept. 25 issue of ACS, ...
... chemist at the National Institute of Standards and ... method for detecting and measuring elusive hazards such ... food or pesticides distributed in soil by wind ... than conventional techniques for detecting traces of these ...
... 2009 Important issues surrounding the quality of food ... creating follow-on biologics (in Canada, subsequent entry biologics) and ... U.S. Pharmacopeial (USP) Convention,s 2009 Annual Scientific Meeting (ASM). ... September 22 to 25. "We have a ...
Cached Biology News:Prototype NIST method detects and measures elusive hazards 2Quality of medicines and food ingredients the focus at USP 2009 Annual Scientific Meeting 2
... 0.1 mL - 25 mL pipets ,Angled acrylic ... most standard square or round pipet cans. Constructed of ... each 76 mm W x 76 mm H x ... ins.). Overall dimensions: 89 mm W x 406 mm ...
... contains choice of PDMS Stamps (3 PDMS ... 200 micron squares or 100 um x ... mm lines, 3 PDMS nano-patterned stamps with ... and pitch of 400 nm, or 3 ...
Request Info...
RECOMBINANT EQUINE IL-4 Product Type: Recombinant Protein...
Biology Products: