Navigation Links
Technique for Creating Authentic Rat Embryonic Stem Cells Published in Cell
Date:12/29/2008

is that it allows the generation of both knock-out rat models, in which the effect of gene deletion is studied, as well as the generation of knock-in models, which involves the insertion of genes, perhaps human genes, in a precisely defined manner. For example, in the case of knock-out models, a lack of response or different response profile to drugs compared with non-engineered animals can provide information on drug efficacy. Alternatively, the insertion of genes such as those involved in drug metabolism in the human liver means that knock-in models can provide information on drug safety & metabolism. Under the terms of its agreement with Edinburgh University, SCS has global exclusive rights to commercialise pluripotent rat stem cells, the specific culture medium used to generate and grow the cells, and rats derived therefrom.

Dr Alastair Riddell, Chief Executive Officer of Stem Cell Sciences, said, "The impact of this new technique could be far-reaching in terms of opening the way to new and more effective drug discovery. Rat models are expected to be highly predictive of human responses to drugs, particularly for in psychiatric, neurological and cardiovascular areas. With this new technique allowing researchers to knock-in human genes it will be possible to conduct drug metabolism and toxicology studies with even higher predictability in rats than ever before. We expect there to be considerable commercial interest from companies wanting to access this exciting technology."

Reference

(1.) Buehr et al., Capture of Authentic Embryonic Stem Cells from Rat Blastocysts, Cell (2008), doi:10.1016/j.cell.2008.12.007

About Stem Cell Sciences plc

Stem Cell Sciences (SCS) is an international research and development company focusing on the commercial application of stem cell biology technologies for drug discovery and regenerative medicine research. Stem Cell Science
'/>"/>

SOURCE Stem Cell Sciences plc
Copyright©2008 PR Newswire.
All rights reserved

Page: 1 2 3

Related biology technology :

1. New technique allows simultaneous tracking of gene expression and movement
2. Imaging Diagnostic Systems is Recognized for Its Advanced Engineering in Time-Resolved Techniques by the US Patent Office
3. Protein-printing technique gives snapshots of immune system defense
4. Prominent Urologist Dr. David B. Samadi Presents Breakthrough Robotic Surgery Techniques on OR Live Webcast
5. Nanoscale dimensioning is fast, cheap with new NIST optical technique
6. Like an arrow: Jumping insects use archery techniques
7. Parallel nano-soldering technique chosen for years top-50 by Nanotech Briefs
8. Pioneering IVF Technique Produces Region's First Pregnancy
9. New technique to compress light could open doors for optical communications
10. New technique produces genetically identical stem cells
11. On the boil: New nano technique significantly boosts boiling efficiency
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/28/2014)... 2014 Research and Markets has announced ... 2014-2018" report to their offering. ... a technique used to determine the size of a particle ... crucial to analyze the size of particles as it can ... is performed to determine the behavior and nature of a ...
(Date:7/26/2014)... Canada Endoscopy Visualization Systems Market Outlook ... Canada Endoscopy Visualization Systems market. The report provides ... units) and average prices (in US dollars) within ... Endoscopy Visualization Systems and Low-End Endoscopy Visualization Systems. ... , The report also provides company shares and ...
(Date:7/25/2014)... July 25, 2014 Amgen (NASDAQ: ... declared a $0.61 per share dividend for the third ... Sept. 5, 2014, to all stockholders of record as ... About Amgen Amgen is committed to ... serious illnesses by discovering, developing, manufacturing and delivering innovative ...
(Date:7/25/2014)... researchers from the University of Leicester has furthered ... the potential to create new materials using nanosized ... published in the prestigious academic journal Physical ... to examine in rich detail the structure and ... an acetylene molecule and a single helium atom. ...
Breaking Biology Technology:Global Particle Size Analysis Market 2014-2018 2Canada Endoscopy Visualization Systems Market Outlook to 2020: MarketResearchReports.Biz 2Canada Endoscopy Visualization Systems Market Outlook to 2020: MarketResearchReports.Biz 3Canada Endoscopy Visualization Systems Market Outlook to 2020: MarketResearchReports.Biz 4Canada Endoscopy Visualization Systems Market Outlook to 2020: MarketResearchReports.Biz 5Amgen Announces 2014 Third Quarter Dividend 2Amgen Announces 2014 Third Quarter Dividend 3Breakthrough laser experiment reveals liquid-like motion of atoms in an ultra-cold cluster 2Breakthrough laser experiment reveals liquid-like motion of atoms in an ultra-cold cluster 3
... the American Academy ... of Dermatology, FREEPORT, N.Y., ... and its natural receptor,OCTN- 1, are a natural part of the skin,s ... in photoaged,skin. The data was presented at the Poster Session at the ...
... Feb. 11 Emisphere,Technologies, Inc. (Nasdaq: EMIS ), ... delivery of therapeutic molecules using its,eligen(R) technology, today announced ... CEO & Investor Conference on February 12, 2008 on,its ... page of the,Emisphere Web site at http://www.emisphere.com/ir.asp ...
... On Monday, January 28, The Royal,Marsden Hospital ... Modulated Arc Therapy (VMAT)* treatment in the ... the treatment, the hospital,used its existing Elekta ... control system., (Logo: http://www.newscom.com/cgi-bin/prnh/20020318/ELEKTALOGO ...
Cached Biology Technology:AGI Dermatics Clinical Data Identifies L-Ergothioneine as Part of Skin's Natural Antioxidant System 2Emisphere Technologies to Web Cast BIO CEO & Investor Conference Presentation February 12 2Elekta Announces First Volumetric Modulated Arc Therapy Cancer Treatment at Royal Marsden Hospital 2
(Date:7/28/2014)... Solanum pennellii , a wild relative of the ... of researchers including the labs headed by Professors Neelima ... of Plant Biology. The new genome information may help ... published July 27 in the journal Nature Genetics ... Aachen University in Germany. The UC Davis labs carried ...
(Date:7/28/2014)... bug hunter, but the target of his work consists ... with special methods and instruments. Benjamin Hause, an assistant ... at Kansas State University, recently published an article about ... an important find in the United States. , "We ... what it was," Hause said. "We used next-generation sequencing ...
(Date:7/28/2014)... July 28, 2014 Research and Markets ... Market in Latin America 2014-2018" report to their ... Biometrics measure and analyze biological data. These systems ... eye retinas, voice patterns, and hand measurements from the ... stored templates. The main purpose of a biometrics system ...
Breaking Biology News(10 mins):Researcher using next-generation sequencing to rapidly identify pathogens 2Researcher using next-generation sequencing to rapidly identify pathogens 3Biometrics Market in Latin America 2014-2018 2
... Could a computer model help stabilize the tuna ... ethanol fuel without jeopardizing food production? Those ... scientists, applied mathematicians, economists, biologists and environmental scientists ... Sustainability, being launched with a $10 million grant ...
... The development of powerful supercomputers capable of ... an eye mark a technological milestone capable of ... business worldwide. Researchers at the University of Miami,s ... with NCAR (National Center for Atmospheric Research), COLA ...
... COLD SPRING HARBOR, N.Y. (Sept. 4, 2008) ... and animalshave biological rhythms, where the timing and duration ... them to adapt and survive, even under fluctuating environmental ... made to understand the molecular basis of these rhythms ...
Cached Biology News:Cornell gets $10 million NSF grant to establish new sustainability institute 2Petascale climate modeling heats up at University of Miami 2Petascale climate modeling heats up at University of Miami 3Interdisciplinary volume on biological rhythms serves as both primer and in-depth resource 2
odz, odd Oz/ten-m homolog 1 [Source:RefSeq_peptide;Acc:NP_055068] Antigen: Recombinant Protein Epitope Signature Tag (PrEST)....
Rabbit polyclonal to FANCE ( Abpromise for all tested applications). entrezGeneID: 2178 SwissProtID: Q9HB96...
Rabbit polyclonal to NIRF ( Abpromise for all tested applications). Antigen: Synthetic peptide derived from residues 186-235 of human NIRF. Entrez Gene ID: 115426 Swiss Protein ID: Q96PU...
...
Biology Products: