Navigation Links
TNI BioTech Acquires Exclusive License To The Portfilio Of Patents Of Dr Ian S. Zagon, Dr. Patricia J. McLauglin And Dr. Jill Smith From The Penn State Research Foundation
Date:2/1/2013

>

Summary of Clinical Trial on the Benefits of OGF in the Treatment of Pancreatic Cancer

In a prospective phase II open-labeled clinical trial performed by Dr. Jill Smith and her colleagues in the Departments of Medicine, Public Health Sciences, Pathology, and Neurosciences and Anatomy at the Pennsylvania State University School of Medicine in Hershey, PA, patients with very advanced pancreatic cancer were treated. These patients had failed prior chemotherapy regimens and were either treated weekly with opioid growth factor (OGF) or entered a hospice program.

Results: Clinical benefit response was experienced by 53% of OGF-treated patients compared to historical controls of 23.8% and 4.8% for gemcitabine and 5-fluorouracil (5-FU), respectively. Of the OGF-treated patients surviving more than eight weeks, 62% showed either a decrease or stabilization in tumor size by computed tomography. The median survival time for the OGF-treated patients was three times that of the untreated hospice patients (65.5 versus 21 days, p < 0.001). No adverse effects on hematologic or chemistry parameters were noted, and quality of life surveys suggested improvement with OGF.

Limitations: Measurements other than survival were not allowed in the control hospice patients, and clinical benefit comparisons were made to historical controls.

Conclusion: OGF biotherapy improves the clinical benefit and prolongs survival in patients with pancreatic cancer by stabilizing disease or slowing progression. The effects of OGF did not adversely alter the patients' quality of life. The use of OGF biotherapy at earlier stages of disease or in combination with chemotherapeutic agents may further improve the outcome of this malignancy.

About TNI BioTech, Inc.

TNI BioTech, Inc., is a biotech company working to combat chronic, life-threatening diseases through the activation modulating the body's immune
'/>"/>

SOURCE TNI BioTech, Inc.
Copyright©2012 PR Newswire.
All rights reserved

Page: 1 2 3 4

Related biology technology :

1. Chief Medical Officers in Biotechs Finally Have Their Own Conference
2. BioSpace Releases 2013 Life Sciences / Biotech Employment Outlook
3. Juventas Therapeutics Hires Biotechnology Veteran Paul Resnick as Vice President of Business Development
4. Riveting Biotechnology Novel, WIRED, Becomes the #1 Technothriller on Amazon
5. Biotechnology guaranteed US$ 100 K to average Brazilian corn growers in four years, according to ABRASEM
6. Riveting Biotechnology Novel, WIRED, Becomes the #1 Technothriller on Amazon
7. 2012 Cotton Biotechnology Award Recipients
8. Ganeden Biotech® Moves Its State-Of-The-Art Lab To Its World Headquarters In Cleveland
9. Biotechnology: Global Industry Guide
10. Join Cato BioVentures and Cancer Advances at Biotech Showcase 2013 & J.P. Morgan 31st Annual Healthcare Conference
11. Biosim Pharmaceuticals, Manufacturers of Generic ACTHAR, to Participate at Biotech Showcase 2013
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/31/2014)... “2014 Deep Research Report ... is a professional and in-depth research report ... Polyurethane Resin basic information, including its definition, ... industry overview. This research covers the international ... well as global industry analysis covering macroeconomic ...
(Date:7/31/2014)... even the entire body to visualize long-range connections between ... a long-time dream of biologists. A study published by ... Cell has now made that dream a ... and human tissue biopsies transparent, while keeping the cellular ... way for a better understanding of brain-body interactions, more ...
(Date:7/31/2014)... , July 31, 2014 Rogne Bioscience, a ... Bay Area , has acquired a licence to ... commercialisation company. The potent anti-inflammatory activity of the peptides ... the University of Oxford,s Sir William Dunn School ... has raised over $1.5 million in seed financing, is ...
(Date:7/31/2014)... San Francisco, California (PRWEB) July 31, 2014 ... expert systems that inform therapeutic decision-making in oncology, today ... on August 14, 2014 to discuss the Company's financial ... to provide an update about the business in the ... live audio call beginning on Thursday, August 14, 2014, ...
Breaking Biology Technology:Polyurethane Resin Industry & Thermoplastic Polyurethane Market (China, Global) Analysis Now at DeepResearchReports.com 2Polyurethane Resin Industry & Thermoplastic Polyurethane Market (China, Global) Analysis Now at DeepResearchReports.com 3Polyurethane Resin Industry & Thermoplastic Polyurethane Market (China, Global) Analysis Now at DeepResearchReports.com 4See-through organs and bodies will accelerate biomedical discoveries 2Oxford licenses anti-inflammatory peptides to San Francisco Bay Area start-up 2Oxford licenses anti-inflammatory peptides to San Francisco Bay Area start-up 3CollabRx, Inc. Schedules First Quarter Fiscal Year 2015 Financial Conference Call and Business Update 2
... 2011 SimPL, the Simple Platform for Learning, is ... regulatory training , eLearning and classroom ... Healthcare administrators and educators spend a great deal of ... for those organizations that want a system that is ...
... Wis., Aug. 11, 2011 Cellular Dynamics International (CDI) ... Grant Program. This grant program will advance researchers, understanding ... types derived from them, and the role and applications ... research, drug discovery and development.   "The ...
... of experts, led by a Case Western Reserve ... bring unrivaled qualities found in one- and two-dimensional ... is to produce new materials for a host ... cells and hydrogen storage devices to lightweight thermal ...
Cached Biology Technology:The SimPL Learning Management System Supports Compliance in Healthcare Facilities 2Cellular Dynamics Launches Innovative Research Grant Program 2Teaming up to build 3-D nanomaterials 2Teaming up to build 3-D nanomaterials 3
(Date:7/31/2014)... Census Bureau, Latinos are the largest minority group in ... Approximately one-third of Latinos are obese and are 1.2 ... Whites. , NYU College of Nursing student researcher ... identify the factors that contribute to this problem by ... on food patterns in Latina women recently published in ...
(Date:7/31/2014)... beneath many of the roughly 156,000 gas stations ... corrosion in parts of underground gas storage tankscorrosion ... of groundwater, a source of drinking water. In ... reported many rapidly corroding gas storage tank components ... associated with use of gasoline-ethanol blends and the ...
(Date:7/31/2014)... experimental vaccine protected 100 percent of animal models against ... , which causes an intestinal disease that kills approximately ... print in Infection and Immunity . , ... non-human primates against the purified toxins produced by ... spore infection, a laboratory model that mimics the human ...
Breaking Biology News(10 mins):NYU research looks to combat US Latina immigrant obesity 2NIST corrosion lab tests suggest need for underground gas tank retrofits 2C. difficile vaccine proves safe, 100 percent effective in animal models 2
... team of neuroengineers based at Brown University has developed ... of relaying real-time broadband signals from up to 100 ... novel low-power device, described in the Journal of ... models for more than year, a first in the ...
... long-term consequences of childhood obesity are well documented, some ... more time to the 3 Rs in educationreading, writing, ... leaving out an important fourth Raerobicscould actually be counterproductive ... for publication in The Journal of Pediatrics ...
... at Wake Forest Baptist Medical Center and colleagues have ... bone marrow that have the natural ability to migrate ... potential to restore healthy tissue in patients with inflammatory ... have IBD, which is characterized by frequent diarrhea and ...
Cached Biology News:Brown unveils novel wireless brain sensor 2Brown unveils novel wireless brain sensor 3Brown unveils novel wireless brain sensor 4Reading, writing, arithmetic, and aerobics -- Evaluating the new 'R' in academic performance 2Research supports promise of cell therapy for bowel disease 2
... is a compact analysis system for the clinical ... a controller, advanced digital signal processing and a ... system includes the Luminex 100, the XY Platform, ... file at the FDA, and partner kits that ...
... nutritious peptone, used in ... of bacterial toxins, and ... bacteria with high nutritional ... Neisseria, Pasteurella, Salmonella and ...
... Ham's F12K medium with 2 mM L-glutamine and ... order to keep the antigens in their native ... are arrayed on a 12-well (5 mm) adhesive ... to enhance cellular attachment and to minimize background ...
Cell Culture Flask, 175 cm, tissue-culture treated polystyrene, barcoded...
Biology Products: