Navigation Links
TNI BioTech Acquires Exclusive License To The Portfilio Of Patents Of Dr Ian S. Zagon, Dr. Patricia J. McLauglin And Dr. Jill Smith From The Penn State Research Foundation
Date:2/1/2013

>

Summary of Clinical Trial on the Benefits of OGF in the Treatment of Pancreatic Cancer

In a prospective phase II open-labeled clinical trial performed by Dr. Jill Smith and her colleagues in the Departments of Medicine, Public Health Sciences, Pathology, and Neurosciences and Anatomy at the Pennsylvania State University School of Medicine in Hershey, PA, patients with very advanced pancreatic cancer were treated. These patients had failed prior chemotherapy regimens and were either treated weekly with opioid growth factor (OGF) or entered a hospice program.

Results: Clinical benefit response was experienced by 53% of OGF-treated patients compared to historical controls of 23.8% and 4.8% for gemcitabine and 5-fluorouracil (5-FU), respectively. Of the OGF-treated patients surviving more than eight weeks, 62% showed either a decrease or stabilization in tumor size by computed tomography. The median survival time for the OGF-treated patients was three times that of the untreated hospice patients (65.5 versus 21 days, p < 0.001). No adverse effects on hematologic or chemistry parameters were noted, and quality of life surveys suggested improvement with OGF.

Limitations: Measurements other than survival were not allowed in the control hospice patients, and clinical benefit comparisons were made to historical controls.

Conclusion: OGF biotherapy improves the clinical benefit and prolongs survival in patients with pancreatic cancer by stabilizing disease or slowing progression. The effects of OGF did not adversely alter the patients' quality of life. The use of OGF biotherapy at earlier stages of disease or in combination with chemotherapeutic agents may further improve the outcome of this malignancy.

About TNI BioTech, Inc.

TNI BioTech, Inc., is a biotech company working to combat chronic, life-threatening diseases through the activation modulating the body's immune
'/>"/>

SOURCE TNI BioTech, Inc.
Copyright©2012 PR Newswire.
All rights reserved

Page: 1 2 3 4

Related biology technology :

1. Chief Medical Officers in Biotechs Finally Have Their Own Conference
2. BioSpace Releases 2013 Life Sciences / Biotech Employment Outlook
3. Juventas Therapeutics Hires Biotechnology Veteran Paul Resnick as Vice President of Business Development
4. Riveting Biotechnology Novel, WIRED, Becomes the #1 Technothriller on Amazon
5. Biotechnology guaranteed US$ 100 K to average Brazilian corn growers in four years, according to ABRASEM
6. Riveting Biotechnology Novel, WIRED, Becomes the #1 Technothriller on Amazon
7. 2012 Cotton Biotechnology Award Recipients
8. Ganeden Biotech® Moves Its State-Of-The-Art Lab To Its World Headquarters In Cleveland
9. Biotechnology: Global Industry Guide
10. Join Cato BioVentures and Cancer Advances at Biotech Showcase 2013 & J.P. Morgan 31st Annual Healthcare Conference
11. Biosim Pharmaceuticals, Manufacturers of Generic ACTHAR, to Participate at Biotech Showcase 2013
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:10/22/2014)... 22, 2014 Nuvilex, Inc. (OTCQB: NVLX) – ... people worldwide are living with diabetes, with  that number ... The global market for diabetes treatments is approximately $500 ... worldwide died from pancreatic cancer.  Pancreatic cancer is the ... in the United States , and ...
(Date:10/20/2014)... Convey Computer , the leader in ... State University won first place in the 2014 ... the team’s solution achieved the highest overall performance in ... place finisher. , Experts from all segments of the ... challenge, using a variety of design tools, hardware and ...
(Date:10/20/2014)... 20, 2014 PureTech , a science ... healthcare problems, announced today the closing of a ... from Invesco Perpetual, a $120 Billion group of ... PureTech,s existing pipeline forward and to advance new ... scientific creativity to really go for the big ...
(Date:10/19/2014)... (PRWEB) October 20, 2014 ... Industry Meeting (ABIM). ABIM will take ... More information about ABIM 2014 is now ... , Delegates representing companies and organizations from ... and obtain information on the latest products ...
Breaking Biology Technology:Nuvilex Brief Analyst Report: Thinking Outside the Box by BrokerBank Securities, Inc. 2Team from Iowa State Wins 2014 MemoCODE Design Contest Using Convey HC-2ex 2Team from Iowa State Wins 2014 MemoCODE Design Contest Using Convey HC-2ex 3PureTech Announces Expansion with Oversubscribed $55M Funding Round 2PureTech Announces Expansion with Oversubscribed $55M Funding Round 3PureTech Announces Expansion with Oversubscribed $55M Funding Round 4PureTech Announces Expansion with Oversubscribed $55M Funding Round 5PureTech Announces Expansion with Oversubscribed $55M Funding Round 6
... decision last week to merge its Imaging and Printing Group ... Systems Group (IPSG) is a major milestone in HPs journey ... combining these two units, HP has a unified and convincing ... may be the key that turns HPs consumer message into ...
... researchers will show off developments in games that offer real-world ... ,The Academic Advanced Distributed Learning Co-Laboratory , WTN and ... how Games are Shaping Business and Learning, which will center ... applied to the workforce. , ,The video game industry has ...
... Business is booming again at the University of Wisconsin-Madisons ... job-seekers. , ,This is the best hiring situation weve seen ... associate director of ECS . Fall 2004 recruiting was ... are expected to attend Career Connection, the colleges spring job ...
Cached Biology Technology:HP charges toward the living room 2HP charges toward the living room 3Businesses and educators to preview video games for training 2Businesses and educators to preview video games for training 3Companies recruiting more UW engineering students 2Companies recruiting more UW engineering students 3Companies recruiting more UW engineering students 4
(Date:10/15/2014)... biophysics textbook and it describes how life functions and ... into biological systems and provides an understanding of the ... how our genes make proteins that control the dynamics ... an organism. It quantifies the principles of life and ... on both large and small scales. The book is ...
(Date:10/15/2014)... Ebola virus is spreading rapidly and to an unexpected ... in the past and the virus shows a new ... recorded before. For this reason, the German National Academy ... Science and Engineering, and the Union of the German ... on the Ebola epidemic today. , In the statement ...
(Date:10/15/2014)... , Oct. 15, 2014 NXT-ID, Inc. (NASDAQ: ... authentication company focused on the growing mobile commerce market releases photos ... in Times Square on Monday October 13 th . ... David Tunnel and angel investor Mr. Chad A. ... , CEO of NXT-ID thanked his investors and employees "for their ...
Breaking Biology News(10 mins):New book about life as seen from physics 2Academies call for consequences from the Ebola virus epidemic 2Academies call for consequences from the Ebola virus epidemic 3Academies call for consequences from the Ebola virus epidemic 4Academies call for consequences from the Ebola virus epidemic 5Photo Release: NXT-ID Inc. Rings Opening Bell of the NASDAQ Stock Market October 13th 2Photo Release: NXT-ID Inc. Rings Opening Bell of the NASDAQ Stock Market October 13th 3
... University of Michigan researchers and their colleagues recently hastened ... trees in a large-scale, long-term experiment to glimpse the ... bark was stripped from each tree to kill it ... the federally funded experiment Forest Accelerated Succession Experiment (FASET) ...
... of Pacific Islands Forestry have submitted a proposal to ... strawberry guava, a South American tree that has invaded ... in 1825 as a garden plant. The scientists are ... and Natural Resources, and Hawai Department of Agriculture, agencies ...
... May 25, 2008, approaching 5 p.m. PDT, NASA scientists will ... because at that time the Phoenix Mars Mission space vehicle ... a soft landing onto the northern Mars terrain called Green ... the Red Planet. The place got its name after analysis ...
Cached Biology News:U-M scientists remove thousands of aspens to glimpse forest's future 2U-M scientists remove thousands of aspens to glimpse forest's future 3Insect release proposed to control exotic strawberry guava 2Phoenix mission to Mars will search for climate clues 2Phoenix mission to Mars will search for climate clues 3
Glycerokinase; from Bacillus stearothermophilus...
... The inductive drives of VARIOMAG Magnetic ... as motors, belts, or mechanical bearings, making ... In addition, the VARIOMAG inductive drive can ... water, dust or microorganisms. This is why ...
...
... FL is equipped with ... measurement technologies that complement ... advanced features of Fluoroskan ... Fluoroskan Ascent FL provides ...
Biology Products: