Navigation Links
Stem cells produce compact, regenerated bone in mandible transplants
Date:3/15/2013

Durham, NC (PRWEB) March 15, 2013

Bone transplantation is a major strategy for the repair of bone defects. However, reconstruction of the mandible (jawbone) has long been a difficult challenge for oral surgeons — at least up to now. A new study in the latest issue of STEM CELLS Translational Medicine shows how stem cells can be used to successfully repair the mandible after a molar extraction and, years later, the new bone is still functioning properly.

Interestingly, the regenerated bone is also hard, rather than the spongy kind normally found in the jaw.

The new study is a follow-up to previous investigations by an international team of researchers in which they discovered that mesenchymal stem cells taken from dental pulp and seeded on a collagen scaffold successfully repaired the mandible bone. In this latest work, they checked on patients who had received the mandible bone grafts three years earlier to assess the stability and quality of the regenerated bone and vessel network.

They found the new bone had normal function and was richly vascularized, although was much more compact than the spongy type normally found in the mandible. The team theorized that, most probably, regeneration of compact bone occurs because grafted dental-pulp stem cells do not follow the local signals of the surrounding spongy bone.

“The mandible is constructed from spongey bone on account of its role linked to the presence of teeth and their movements, so regeneration of a compact, rather than a spongy bone type, is difficult to justify physiologically. We concluded, therefore, that grafted dental pulp stem cells do not pursue the local environmental signals emanating from the alveolar bone surrounding the graft site,” said Gianpaolo Papaccio, M.D., Ph.D., of the Department of Experimental Medicine at Second University of Naples, Naples, Italy. He led the study team that included colleagues from Second University
'/>"/>

Source: PRWeb
Copyright©2012 Vocus, Inc.
All rights reserved

Page: 1 2 3

Related biology technology :

1. New method for producing precursor of neurons, bone and other important tissues from stem cells
2. Biocept and Academic Collaborators to Present Posters at San Antonio Breast Cancer Symposium on Circulating Tumor Cells (CTCs)
3. Notre Dame researchers develop paint-on solar cells
4. Cord Blood America Announces Exclusive Agreement With National Childrens Leukemia Foundation to Store Stem Cells
5. Stem Cells: Worldwide Markets for Transplantation, Cord Blood Banking and Drug Development
6. In solar cells, tweaking the tiniest of parts yields big jump in efficiency
7. Mesenchymal Stem Cells Have New Cell Culture Environment
8. Discovery in Nature elucidates immune cells in skin and supports novel vaccine approach
9. Scientists Discover How a Bacterial Pathogen Breaks Down Barriers to Enter and Infect Cells
10. IntelliCell BioSciences Signs Technology Licensing Agreement with Stem Cells 21 Thailand
11. Study dusts sugar coating off little-known regulation in cells
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:3/26/2015)... Louisville, CO (PRWEB) March 26, 2015 ... agency has formed a strategic alliance with Designing Gig ... to their clients. , “Forging this alliance ... company. Now we can extend a comprehensive, end-to-end, ... design, development, strategy, and execution,” said Chuck Miller, president ...
(Date:3/26/2015)... CINCINNATI , March 26, 2015 ... SHPG ) and Cincinnati Children,s Hospital Medical Center ... rare diseases. The goal of the collaboration is to ... diseases with high unmet medical need combining Shire,s ... expertise. As a nationally ranked hospital, Cincinnati Children,s ...
(Date:3/26/2015)... PAREXEL International Corporation (Nasdaq: ... organization , announced today that the Company ... all of the business assets of privately-owned Quantum ... specialized pharmacovigilance services, based in Chandigarh, India.  ... monitoring, and prevention of adverse effects with ...
(Date:3/26/2015)... (PRWEB) March 26, 2015 "In America," the ... the United States that is hosted by legendary film actor ... topic of botany in an upcoming segment. , Botany ... in reality it is actually quite a bit more complicated ... of different types of living organisms, from the smallest bacteria ...
Breaking Biology Technology:The Market Element LLC and Designing Gig LLC Form Strategic Alliance 2Shire and Cincinnati Children's Establish Rare Disease Research Collaboration 2Shire and Cincinnati Children's Establish Rare Disease Research Collaboration 3Shire and Cincinnati Children's Establish Rare Disease Research Collaboration 4Shire and Cincinnati Children's Establish Rare Disease Research Collaboration 5PAREXEL Announces Execution of Definitive Agreement to Acquire Quantum Solutions India, Strengthening Leadership In Pharmacovigilance Services 2PAREXEL Announces Execution of Definitive Agreement to Acquire Quantum Solutions India, Strengthening Leadership In Pharmacovigilance Services 3PAREXEL Announces Execution of Definitive Agreement to Acquire Quantum Solutions India, Strengthening Leadership In Pharmacovigilance Services 4
... Wis. - Gov. Jim Doyle has announced the allocation of ... ethanol plant in the Juneau County village of Necedah. , ,The ... Necedah construct a new well and water main that will be ... produce 50 million gallons of ethanol annually and employ between 35 ...
... ninth in a series of articles on developing start-up ... recent article focused on worker classification. , , ... developed. Lawyers and accountants are on board. The intellectual ... name has been chosen. Perhaps workers, other than founders, ...
... one the nation's major credit-card processing companies, agreed to be ... Kravis Roberts & Co. , for $29 billion. The New ... the 10 largest buyouts ever and signals the continued might ... and eager institutional investors like pension funds. , ,What does ...
Cached Biology Technology:Early Stage, Step 9: Raising capital in the securities landscape 2Early Stage, Step 9: Raising capital in the securities landscape 3Early Stage, Step 9: Raising capital in the securities landscape 4Of private equity, research, and drug development 2Of private equity, research, and drug development 3Of private equity, research, and drug development 4Of private equity, research, and drug development 5
(Date:3/17/2015)... DIEGO , March 17, 2015 ... emotion analytics software, today announced general availability of ... web service for the analysis of facial expressions. ... experience advertising, media content, products and services. It ... attention, engagement and sentiment - as derived from ...
(Date:3/12/2015)... WINSTON-SALEM, N.C. , March 12, 2015 ... afternoon at Brenner Children,s Hospital, part of Wake Forest ... an outreach initiative for the 2015 ACC Men,s Basketball ... taking pictures with them and getting their autographs. ... Wake Forest Baptist. It is the only children,s hospital ...
(Date:3/11/2015)... , March 11, 2015   The Sync ... platform to scientifically measure and harness music to ... real-time biometrics and objective measurements of physiology, enabling ... at scale in large populations. It is designed ... and clinicians perform rigorous studies and accelerate the ...
Breaking Biology News(10 mins):New Emotient Web Service Measures Audience Response Using On-Demand Facial Expression Analysis 2New Emotient Web Service Measures Audience Response Using On-Demand Facial Expression Analysis 3New Emotient Web Service Measures Audience Response Using On-Demand Facial Expression Analysis 4Introducing The Sync Project, a Global Collaboration Harnessing the Scientific Potential of Music for Health 2Introducing The Sync Project, a Global Collaboration Harnessing the Scientific Potential of Music for Health 3
... the southern coast of Baja California, Mexico, scientists have been ... as part of an effort to assess and eliminate threats ... are shocking: almost 3,000 sea turtles were found dead along ... 2003 to 2007. Led by Hoyt Peckham, a ...
... Ph.D., professor and head of the Computational Neurobiology Laboratory ... Institute of Medicine, the IOM has announced. Election to ... in the fields of health and medicine and recognizes ... to service. "It is a ...
... NJIT professor, who has discovered new communication channels ... communicate data through these channels, will be honored ... Hall of Fame. His work will eventually allow ... communicate information and data faster and more reliably ...
Cached Biology News:Study finds high mortality of endangered loggerhead sea turtles in Baja California 2Salk researcher Terry Sejnowski elected to Institute of Medicine 2NJIT professor's research suggests changes in underwater data communications 2
Normal donkey serum collected from healthy normal donkeys....
This BioSolution package is excellent for doing fluorescence thermal melt experiments on nucleic acids, studies involving biomolecular interactions, protein folding experiments, and more!...
... Fc OxyBURST Green reagent (F-2902) was developed ... University to permit measurement of the kinetics ... subsequent oxidative burst directly in the phagovacuole.2 ... of bovine serum albumin (BSA) that has ...
... Error-free cloning of BAC (100+kb), fosmid ... Greater insert stability than any othe BAC ... for high yields and easy recombinant DNA ... or transcription-free (pSMART VC) vectors for the ...
Biology Products: