Navigation Links
Stem cells produce compact, regenerated bone in mandible transplants
Date:3/15/2013

Durham, NC (PRWEB) March 15, 2013

Bone transplantation is a major strategy for the repair of bone defects. However, reconstruction of the mandible (jawbone) has long been a difficult challenge for oral surgeons — at least up to now. A new study in the latest issue of STEM CELLS Translational Medicine shows how stem cells can be used to successfully repair the mandible after a molar extraction and, years later, the new bone is still functioning properly.

Interestingly, the regenerated bone is also hard, rather than the spongy kind normally found in the jaw.

The new study is a follow-up to previous investigations by an international team of researchers in which they discovered that mesenchymal stem cells taken from dental pulp and seeded on a collagen scaffold successfully repaired the mandible bone. In this latest work, they checked on patients who had received the mandible bone grafts three years earlier to assess the stability and quality of the regenerated bone and vessel network.

They found the new bone had normal function and was richly vascularized, although was much more compact than the spongy type normally found in the mandible. The team theorized that, most probably, regeneration of compact bone occurs because grafted dental-pulp stem cells do not follow the local signals of the surrounding spongy bone.

“The mandible is constructed from spongey bone on account of its role linked to the presence of teeth and their movements, so regeneration of a compact, rather than a spongy bone type, is difficult to justify physiologically. We concluded, therefore, that grafted dental pulp stem cells do not pursue the local environmental signals emanating from the alveolar bone surrounding the graft site,” said Gianpaolo Papaccio, M.D., Ph.D., of the Department of Experimental Medicine at Second University of Naples, Naples, Italy. He led the study team that included colleagues from Second University
'/>"/>

Source: PRWeb
Copyright©2012 Vocus, Inc.
All rights reserved

Page: 1 2 3

Related biology technology :

1. New method for producing precursor of neurons, bone and other important tissues from stem cells
2. Biocept and Academic Collaborators to Present Posters at San Antonio Breast Cancer Symposium on Circulating Tumor Cells (CTCs)
3. Notre Dame researchers develop paint-on solar cells
4. Cord Blood America Announces Exclusive Agreement With National Childrens Leukemia Foundation to Store Stem Cells
5. Stem Cells: Worldwide Markets for Transplantation, Cord Blood Banking and Drug Development
6. In solar cells, tweaking the tiniest of parts yields big jump in efficiency
7. Mesenchymal Stem Cells Have New Cell Culture Environment
8. Discovery in Nature elucidates immune cells in skin and supports novel vaccine approach
9. Scientists Discover How a Bacterial Pathogen Breaks Down Barriers to Enter and Infect Cells
10. IntelliCell BioSciences Signs Technology Licensing Agreement with Stem Cells 21 Thailand
11. Study dusts sugar coating off little-known regulation in cells
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:3/3/2015)... , Mar. 03, 2015 Research and Markets ... addition of Jain PharmaBiotech,s new report "Personalized ... their offering. , The aim ... match the right drug to the right patient ... appropriate treatment for a patient according to his/her ...
(Date:3/3/2015)... , March 3, 2015  Johnson & Johnson ... South San Francisco (JLABS @SSF), a ... South San Francisco, Calif. The ... up to 50 startups from across the healthcare spectrum ... The first resident startups have been ...
(Date:3/3/2015)... , March 3, 2015  Synthetic Biologics, Inc. (NYSE ... and diseases, with a focus on protecting the microbiome, announced ... scheduled to present at the 27th Annual ROTH Conference being ... Laguna Niguel in Dana Point, CA. ... March 10, 2015 at 1:00 p.m. (Pacific Time). ...
(Date:3/3/2015)... GlobalStemCellsGroup.com has recruited Mario Camacho Alcocer ... researcher and founding partner of Criogenix SA de CV ... professors who will teach the “Diplomat in Cell Therapy ... is a private company registered in the National Record ... (RENIECYT). , Camacho Alcocer will teach two-day, interactive training ...
Breaking Biology Technology:Global Personalized Medicine Market Report 2015 - Scientific and Commercial Aspects 2014-2024 2Global Personalized Medicine Market Report 2015 - Scientific and Commercial Aspects 2014-2024 3Johnson & Johnson Innovation Opens JLABS @South San Francisco and Announces First Five Resident Startups 2Johnson & Johnson Innovation Opens JLABS @South San Francisco and Announces First Five Resident Startups 3Johnson & Johnson Innovation Opens JLABS @South San Francisco and Announces First Five Resident Startups 4Johnson & Johnson Innovation Opens JLABS @South San Francisco and Announces First Five Resident Startups 5Synthetic Biologics to Present at the 27th Annual ROTH Conference 2Mario Camacho Alcocer Joins Global Stem Cells Group Faculty 2Mario Camacho Alcocer Joins Global Stem Cells Group Faculty 3
... now available for Robocycler 96 temperature,cyclers ... ,Jason Capodanno Michael Rahilly ,Stratagene Cloning Systems, Inc. ... for RoboCycler , 96 temperature cyclers, ... Assembly for RoboCycler 96 cyclers is supplied,with a software ...
... robust, high-fidelity PCR,amplification , Holly Hogrefe Brad ... Janice Cline Frances Bai Jeff Amberg ... release of pfuturbo DNA polymerase,* , ,an improved version ... polymerase is a blend of cloned Pfu DNA,polymerase and ...
... , Novel Herculase Hotstart DNA polymerase results in greater ... , Michael Borns Brad Scott ... Stratagenes Herculase , ... enzyme for difficult PCR applications, particularly those involving long, , ...
Cached Biology Technology:Oil-Free PCR Using the Hot Top Assembly 2Oil-Free PCR Using the Hot Top Assembly 3Oil-Free PCR Using the Hot Top Assembly 4Oil-Free PCR Using the Hot Top Assembly 5Oil-Free PCR Using the Hot Top Assembly 6Oil-Free PCR Using the Hot Top Assembly 7Novel PCR Enhancing Factor Improves Performance of Pfu DNA Polymerase 2Novel PCR Enhancing Factor Improves Performance of Pfu DNA Polymerase 3Novel PCR Enhancing Factor Improves Performance of Pfu DNA Polymerase 4Novel PCR Enhancing Factor Improves Performance of Pfu DNA Polymerase 5Novel PCR Enhancing Factor Improves Performance of Pfu DNA Polymerase 6Novel PCR Enhancing Factor Improves Performance of Pfu DNA Polymerase 7Novel PCR Enhancing Factor Improves Performance of Pfu DNA Polymerase 8Novel PCR Enhancing Factor Improves Performance of Pfu DNA Polymerase 9Novel PCR Enhancing Factor Improves Performance of Pfu DNA Polymerase 10Novel PCR Enhancing Factor Improves Performance of Pfu DNA Polymerase 11The Best Enzyme for the Toughest PCR Challenges Improved with New Hot-Start Feature 2The Best Enzyme for the Toughest PCR Challenges Improved with New Hot-Start Feature 3
(Date:1/22/2015)... CHICAGO , Jan. 9, 2015 Valid S.A. ("Company") ... the market in general the State of Washington,s ... contract for a new enrollment and central issuance system for ... The project planning and development will start ...
(Date:1/22/2015)... Fla. , Jan. 13, 2015  Today, FreeWavz ... technology, launched its crowdfunding campaign on Fundable, ... the build of production capacity to meet customer ... Photo - http://photos.prnewswire.com/prnh/20150113/168790 ...
(Date:1/22/2015)... , Jan. 15, 2015  BellBrook Labs, a ... discovery, announced the launch of a TR-FRET (time ... company,s Transcreener UDP Assay, a high throughput screening ... new assay will allow for sensitive detection of ...
Breaking Biology News(10 mins):Valid USA Signs Contract For Washington Driver's License Issuance 2FreeWavz Launches on Fundable to Drive Speed-to-Market in 2015 2BellBrook Labs Launches a High Throughput Screening Assay for Glycosyltransferases with TR-FRET Readout 2
... the prospect of using nanoparticles in biomedical applications and ... of the miniscule materials. Scientists at the University of ... kinds of nanoparticles damage cell membranes—enough to cause cell ... prevented. , "If you're inventing these sorts of materials, ...
... (Ed : testosterone isn't a protein, it's a ... allows it to function properly. Now Stanford University scientists ... when a protein molecule attached to a gold nanoparticle ... the same principle as ordinary pH tests that measure ...
... and maintenance of human embryonic stem cells in the ... University of California, San Diego (UCSD) School of Medicine ... Published in the April 2005 issue of the journal ... enriched by a human protein called activin A are ...
Cached Biology News:Probing The Promise And Perils Of Nanoparticles 2Probing The Promise And Perils Of Nanoparticles 3Scientists develop new color-coded test for protein folding 2UCSD researchers maintain stem cells without contaminated animal feeder layers 2
...
... new application for DNA and protein ... Expression makes complex computational analyses of ... the very latest computing technology to ... sequences are analysed. Features include: Sequence ...
... Solution is a comprehensive suite of ... specifically designed to reliably extract biological ... genomic studies containing thousands of samples, ... efficient and will analyze large data ...
...
Biology Products: