Navigation Links
Sofie Biosciences Is Awarded a US Patent on a Family of Novel PET Probes for Use in Oncology and Immunology
Date:1/24/2012

CULVER CITY, Calif., Jan. 24, 2012 /PRNewswire/ -- Sofie Biosciences, Inc., offering a comprehensive range of products from pre-clinical PET imaging systems to new PET molecular imaging probes to better understand human disease, has been told that a U.S. Patent (8,101,740) will be granted by the United States Patent Office on technology that has been exclusively licensed to Sofie. The patent covers a family of novel PET probes, known as [18F]FAC.

Positron Emission Tomography (PET) is a molecular imaging technology that utilizes minute amounts of labeled molecules ("probes") to target and measure biological and pharmacological processes. Basic scientists can use the same probes to examine cells and mice, as physicians do in patients to visualize and characterize the biology of disease, monitor its progression, and evaluate therapeutic efficacy.

Basic and clinical scientists at UCLA invented this novel PET probe, [18F]FAC, which was created by a slight modification of the drug molecule, gemcitabine, one of the most common drugs for cancer.  Cancer cells lack the normal checks and balances to limit cell growth.  [18F]FAC provides an in vivo imaging assay of cell growth known as the DNA salvage pathway.  Tumors use the salvage pathway to provide high rates of DNA replication for their uncontrolled growth of cells containing malignant instructions.

[18F]FAC measures the enzyme, dCK, which controls the rate of DNA production through the salvage pathway. Cancer drugs like gemcitabine use dCK to convert the drug into a pharmacologically active product that blocks the high rates of DNA replication for growth of malignant cells, and induces DNA damage in cancer cells. One of Sofie's objectives with [18F]FAC is to use PET imaging to allow physicians the means to search throughout the body for tumors that will respond to drugs that target dCK (like gemcitabine and other drugs), thus enabling more patient-specific treatment selecti
'/>"/>

SOURCE Sofie Biosciences
Copyright©2010 PR Newswire.
All rights reserved

Page: 1 2 3

Related biology technology :

1. Sofie Biosciences is Awarded a DOE Phase I SBIR to Commercialize Microscale Radiochemistry Platform
2. Monogram Biosciences to Present at the Thomas Weisel Partners Healthcare Conference 2008
3. Carna Biosciences Signs Reagent Supply Agreement with Caliper Life Sciences
4. Pressure BioSciences, Inc. to Discuss Second Quarter 2008 Financial Results and Provide Business Update
5. Milestone Biosciences, LLC Further Strengthens Executive Management Team
6. Pressure BioSciences, Inc. Reports Second Quarter 2008 Financial Results and Provides Business Update
7. Access Pharmaceuticals Licenses MuGard to Milestone Biosciences, LLC for North America
8. Pressure BioSciences, Inc. Releases Novel, PCT-dependent Sample Preparation Kit for Systems Biology Studies
9. Neurocrine Biosciences to Present at Thomas Weisel Healthcare Conference and the NewsMakers in the Biotech Industry Conference
10. Start-Up and Emerging Biotech Companies Will Tell Their Stories at Biosciences Showcase Planned for MichBio Expo
11. Ardea Biosciences to Present Data on Lead MEK inhibitor, RDEA119, at EORTC-NCI-AACR Symposium
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:5/26/2015)... Mass. , May 26, 2015  Alere Inc. (NYSE: ... result of its failure to timely file its Quarterly Report ... 2015 (the "Form 10-Q"), it has received a notice from ... is not in compliance with the NYSE,s continued listing requirements ... the NYSE Listed Company Manual. The reason ...
(Date:5/26/2015)... ORANGEBURG, N.Y. , May 26, 2015 /PRNewswire/ ... products and solutions, today announced that Oakwood Healthcare ... been selected as the winning entry in ... recognizing industry professionals who display excellence in building ... services (ES) teams in healthcare facilities.  ...
(Date:5/26/2015)... 26. mája 2015 Kevin Xu ... rodiny prezidentom Barackovi Obamovi a Billovi Clintonovi za ... stratou Dr. Rongxiang Xu , otca Kevina. ... Dr. Xu bol pionier, inovátor, humanitárny ... odhodlanie v oblasti vedy a príkladné vedenie svojej ...
(Date:5/26/2015)... TORONTO , May 26, 2015 /PRNewswire/ - Fluorinov ... appointment of Luke M. Beshar to its ... adding financial and pharmaceutical industry expertise as Fluorinov accelerates ... of the Fluorinov team, it is a pleasure to ... had a significant impact on the strategy, financial strength ...
Breaking Biology Technology:PDI Announces Winner in Delivering the Difference Contest 2PDI Announces Winner in Delivering the Difference Contest 3Dr. Rongxiang Xu, O legende 2Luke M. Beshar Appointed to Fluorinov Pharma Board of Directors 2Luke M. Beshar Appointed to Fluorinov Pharma Board of Directors 3
... sessions of the 2006 Fuel Ethanol Workshop & Expo ... State Senate for rejecting a proposed ethanol mandate ... has given them one more reason to be disappointed. ... ethanol incentive proposed by Governor Jim Doyle . The ...
... of discussion in the blogosphere, a new comparison shopping ... in Madison for public beta testing, with a permanent ... , is designed to be more "transparent" and more ... engines from Google, Yahoo!, or MSN, and accomplish this ...
... 19 and 20 at the Drake Hotel in Chicago, ... legal, engineering and due diligence providers gathered at the ... small and middle markets ($10 million to $1 billion) ... "maximizing the value of your brand and intellectual property" ...
Cached Biology Technology:Joint Finance blocks Doyle ethanol measure 2Joint Finance blocks Doyle ethanol measure 3Jellyfish launches comparative shopping website 2Some great insights into the current Mergers & Acquisitions Market 2Some great insights into the current Mergers & Acquisitions Market 3Some great insights into the current Mergers & Acquisitions Market 4Some great insights into the current Mergers & Acquisitions Market 5
(Date:5/11/2015)... , May 11, 2015  Synaptics Incorporated (NASDAQ: ... interface solutions, today announced the appointment of ... Chief Financial Officer, reporting to Rick Bergman ... current Chief Financial Officer, Kathleen Bayless , ... Mr. Ali brings extensive financial management ...
(Date:5/7/2015)... , May 7, 2015 ... sensors, FPC1022 and FPC1035, FPC,s smallest touch fingerprint ... are mainly considered for integration on the backside ... smartphone OEMs increased possibilities to integrate touch fingerprint ... size also improves possibilities for module manufacturers to ...
(Date:4/27/2015)... LAUDERDALE, Fla. , Apr. 27, 2015 ... of access control and security systems is pleased to ... the company as a consultant and member of its ... is widely known as a thought leader in ... Distance Learning Technology Group, and has published studies and ...
Breaking Biology News(10 mins):Synaptics Appoints Wajid Ali as Senior Vice President and Chief Financial Officer 2FPC Introduces its Smallest Touch Fingerprint Sensors to Date 2Profile Solutions Names Medicinal Cannabis, Agriculture and Technology Expert Dr. Gerry Bedore to its Scientific Advisory Board 2Profile Solutions Names Medicinal Cannabis, Agriculture and Technology Expert Dr. Gerry Bedore to its Scientific Advisory Board 3Profile Solutions Names Medicinal Cannabis, Agriculture and Technology Expert Dr. Gerry Bedore to its Scientific Advisory Board 4
... Carnivores in the Iberian Peninsula, such as the Iberian lynx, ... to changing climatic conditions and that can even survive in ... the innate ability of ticks to adapt according to climate. ... the climate, habitat or movement patterns of people and goods. ...
... bear. They may have to go months without eating. Their ... to that the melting of Arctic sea ice due to climate ... it,s easy to see why polar bears worldwide are in trouble. ... bright spot. In a study of PCBs in polar bear cubs ...
... chromosomal abnormality in children with a deadly form of ... survival, clinician scientists at The University of Nottingham have ... Children,s Brain Tumour Research Centre as part of a ... test to allow doctors to identify youngsters who are ...
Cached Biology News:Ticks can adapt to the Spain's climatic diversity 2PCBs levels down in Norwegian polar bears 2PCBs levels down in Norwegian polar bears 3Genetic abnormality offers diagnostic hope for children's cancer 2Genetic abnormality offers diagnostic hope for children's cancer 3
... thermal cycler, flexible on your protocols, easy on ... performance, high sample throughput instrument at a highly ... block format: The truly user-friendly fully interchangeable block ... matter of seconds without the need of any ...
Preparation Note: by a modification of the procedure of C.W. Hancher et al., Biotechnol. Bioeng. 11, 1055 (1969) Assay: ~ 20 A 260 /mg Solubility: water 10 mg/mL, clear, light-yellow Suitab tst...
A collection of 42 spots with normal tissues from different organs of C57 mice, rat and human....
... Life Science FLA-7000 excels at fluorescent and ... documentation. It features four easy-to-access filters (filters ... filter for Imaging Plates) for upgrading flexibility. ... choice of four kinds of excitation laser ...
Biology Products: