Navigation Links
Silence Therapeutics Receives Comprehensive Protection for RNAi Structural Modification Technology in Single European Patent
Date:10/20/2010

LONDON, Oct. 20 /PRNewswire/ -- Silence Therapeutics plc (AIM: SLN) ("Silence" or the "Company") announces that the European Patent Office (EPO) has granted a new patent that provides broad protection on novel aspects of the RNAi structural modification technology known as the "Zamore Design Rules."  European patent number 1 633 890 titled "Methods and Compositions for Enhancing the Efficacy and Specificity of RNAi" was published today in the European Patent Bulletin.  The European patent covers various breakthrough structural modification methods and compositions which Silence believes are fundamental for the development and commercialization of RNAi therapeutics with enhanced efficacy.

"The granting of this comprehensive patent in Europe is a significant milestone for Silence in our ongoing effort to build one of the world's leading RNAi intellectual property positions.  We have consistently built a strong IP estate around the Zamore technology in the U.S. and have now extended our global coverage to Europe with the granting of this critical patent," stated Philip Haworth, Ph.D., chief executive officer of Silence Therapeutics.  "We have often stated our belief that the 'Zamore Design Rules' represent significant IP to enable the process of bringing effective RNAi therapeutics to market.  With this latest patent grant from the EPO, we are excited to be able to offer potential collaborators or licensing partners access to this strongly protected Zamore technology in both the U.S. and Europe."

The issued patent's method and composition claims include:

  • Methods of enhancing the ability of an antisense strand of an RNAi agent to act as a guide strand
  • RNAi or siRNA agents for enhancing silencing of a target mRNA in a subject
  • Compositions for siRNA duplexes include pre-miRNA and shRNA and vectors to perform the methods described herein

Silence owns excl
'/>"/>

SOURCE Silence Therapeutics plc
Copyright©2010 PR Newswire.
All rights reserved

Page: 1 2 3

Related biology technology :

1. Silence Therapeutics Partner Quark Signs Exclusive Option Agreement With Novartis for Development and Commercialisation of QPI-1002
2. Silence Therapeutics Expands RNAi Structural Modification IP Portfolio With Issuance of New U.S. Patent
3. Silence Therapeutics Issued Novel RNAi Patent Covering High-Value Cancer Target in United States
4. Silence Therapeutics Appoints New Vice President of Research
5. Silence Therapeutics to Present at 12th Annual BIO CEO & Investor Conference
6. National Ovarian Cancer Coalition and PureOlogy to Host First Annual NOCC and PureOlogys Walk to Break the Silence on Ovarian Cancer
7. Precision Therapeutics President and CEO Sean McDonald Recognized as Pittsburgh Technology Council Tech 50 CEO of the Year
8. Fate Therapeutics Announces Collaboration With BD to Develop and Commercialize Induced Pluripotent Stem Cell Technology
9. Northwest Biotherapeutics to Present at Inaugural Cancer Immunotherapy Conference
10. Orexigen® Therapeutics Announces Upcoming Data Presentations at the 28th Annual Scientific Meeting of The Obesity Society
11. Cell Therapeutics, Inc. (CTI) to Present at 9th Annual BIO Investor Forum
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:8/28/2015)... ... August 28, 2015 , ... Pittcon is pleased to ... a session on chemical spectroscopic imaging at JASIS 2015 (Japan Analytical & Scientific ... analytical and scientific instruments show which will be held at International Conference Hall ...
(Date:8/27/2015)... Poway, CA (PRWEB) , ... August 27, 2015 ... ... a unique opportunity for venture capital funds, investment firms and animal health companies ... the Forum have raised $160 million. Several have also received licensing agreements or ...
(Date:8/27/2015)... Fla. , Aug. 27, 2015 The ... that a patient,s eyes—and life—were saved by doctors at ... , working with NNFF, NovaBay Pharmaceuticals and Dr. ... Care Center at Seton Medical Center in ... successful treatment used a breakthrough approach, pioneered by Dr. ...
(Date:8/27/2015)... YORK , August 27, 2015 ... enhancing image processing functions in the human vision system, announced ... point guard Chris Paul to develop ... players who want to improve their real-life on-court performance. ... the court, whether it is shooting a ball or blocking ...
Breaking Biology Technology:U.S. Symposium on Imaging Organized by Pittcon’s Program Chairman Chuck Gardner 2U.S. Symposium on Imaging Organized by Pittcon’s Program Chairman Chuck Gardner 3VetStem Biopharma, Inc. Among Seventeen Companies Selected to Present at the KC Animal Health Investment Forum on September 1st 2015 2VetStem Biopharma, Inc. Among Seventeen Companies Selected to Present at the KC Animal Health Investment Forum on September 1st 2015 3Patient's Life and Eyes Saved from Gruesome Flesh-Eating Infection Consuming Her Face 2Patient's Life and Eyes Saved from Gruesome Flesh-Eating Infection Consuming Her Face 3Eight-Time All-Star Chris Paul and GlassesOff Partner to Develop Innovative Mobile App Designed to Improve On-Court Performance 2Eight-Time All-Star Chris Paul and GlassesOff Partner to Develop Innovative Mobile App Designed to Improve On-Court Performance 3
... ... ... ... ...
... ... ... ... ...
... ... ... ... ...
Cached Biology Technology:China-Biotics, Inc. Appointed Grayling as Strategic Investor Relations Advisor 2China-Biotics, Inc. Appointed Grayling as Strategic Investor Relations Advisor 3China-Biotics, Inc. Appointed Grayling as Strategic Investor Relations Advisor 4China-Biotics, Inc. Appointed Grayling as Strategic Investor Relations Advisor 5China-Biotics, Inc. Appointed Grayling as Strategic Investor Relations Advisor 6China-Biotics, Inc. Appointed Grayling as Strategic Investor Relations Advisor 7Funds Boost Research into Causes, Interventions for Age-Related Cognitive Decline 2Funds Boost Research into Causes, Interventions for Age-Related Cognitive Decline 3Funds Boost Research into Causes, Interventions for Age-Related Cognitive Decline 4Funds Boost Research into Causes, Interventions for Age-Related Cognitive Decline 5Funds Boost Research into Causes, Interventions for Age-Related Cognitive Decline 6Funds Boost Research into Causes, Interventions for Age-Related Cognitive Decline 7Funds Boost Research into Causes, Interventions for Age-Related Cognitive Decline 8Funds Boost Research into Causes, Interventions for Age-Related Cognitive Decline 9Funds Boost Research into Causes, Interventions for Age-Related Cognitive Decline 10Funds Boost Research into Causes, Interventions for Age-Related Cognitive Decline 11Funds Boost Research into Causes, Interventions for Age-Related Cognitive Decline 12Doctors and First Responders Rely on Oberthur Technologies in Times of Emergency 2Doctors and First Responders Rely on Oberthur Technologies in Times of Emergency 3Doctors and First Responders Rely on Oberthur Technologies in Times of Emergency 4Doctors and First Responders Rely on Oberthur Technologies in Times of Emergency 5
(Date:8/6/2015)... , Aug. 6, 2015 Synaptics ... of human interface solutions, today announced collaboration with ... on Windows 10. Microsoft leveraged Synaptics, deep expertise ... operating system. Through stringent testing, ... fully certified with Microsoft,s Precision TouchPad (PTP) specification ...
(Date:8/5/2015)... , August 5, 2015 Transparency ... "Facial Recognition Market - Global Industry Analysis, Size, Share, ... market for facial recognition is forecast to reach US$ ... increased demand for surveillance systems by civil and government ... of crimes and terrorist activities across the globe that ...
(Date:8/4/2015)... 04, 2015 ... announced the addition of the "Digital ... Service), Sub-Segment (Computer Forensics, Network Forensics, Mobile ... Service, Vertical and Region - Global Forecast ... By Component (Hardware, Software, and ...
Breaking Biology News(10 mins):Synaptics Chosen for Human Interface Co-Development on Windows 10 2Facial Recognition Market Expected to Reach US$ 2.67 Bn by 2022, at a CAGR of 9.5% From 2015 - 2022: Transparency Market Research 2Facial Recognition Market Expected to Reach US$ 2.67 Bn by 2022, at a CAGR of 9.5% From 2015 - 2022: Transparency Market Research 3Facial Recognition Market Expected to Reach US$ 2.67 Bn by 2022, at a CAGR of 9.5% From 2015 - 2022: Transparency Market Research 4Facial Recognition Market Expected to Reach US$ 2.67 Bn by 2022, at a CAGR of 9.5% From 2015 - 2022: Transparency Market Research 5Facial Recognition Market Expected to Reach US$ 2.67 Bn by 2022, at a CAGR of 9.5% From 2015 - 2022: Transparency Market Research 6Digital Forensics Market - The Market Represents a Compound Annual Growth Rate (CAGR) of 11.3% From 2015 to 2020 2
... WEST LAFAYETTE, Ind. - Honeybee populations have been ... may have identified one of the factors that cause ... found dead in and around hives from several apiaries ... neonicotinoid insecticides, which are commonly used to coat corn ...
... of Oviedo (Spain) have come up with a way of tagging ... it has been detonated. Based on the addition of isotopes, the ... fish and those from a fish farm, such as trout and ... and living beings has just been presented in this month,s issue ...
... experts at the University of California, Santa Cruz and ... of seven advanced robotic surgery systems for use by ... a round of final tests, five of the systems ... University, Johns Hopkins University, University of Nebraska, UC Berkeley, ...
Cached Biology News:Researchers: Honeybee deaths linked to seed insecticide exposure 2Researchers: Honeybee deaths linked to seed insecticide exposure 3Explosives and fish are traced with chemical tags 2'Open-source' robotic surgery platform going to top medical research labs 2
Mouse Activin RIB/ALK-4 MAb (Clone 207304)...
... 19 x 29 cm, 1. One ... staining of Coomassie Blue or silver-stain gels ... blots for high sensitivity ECL detection and ... volume, and processing time.Proven design for consistent, ...
Cytidine 5'-Triphosphate, Sodium (CTP), 1 g. Category: Nucleotides & Enzymes & Biochemicals, Nucleotides, Additional Nucleotide Products....
... Reagent Pack, 1. Contains reagents for ... mouse and rabbit primary antibodies. Designed for ... reagents are not included, but the system ... Category: Blotting & Labeling & Detection, ...
Biology Products: