Navigation Links
Silence Therapeutics' Partner Quark Signs Exclusive Option Agreement With Novartis for Development and Commercialisation of QPI-1002
Date:8/19/2010

LONDON, Aug. 19 /PRNewswire/ -- Silence Therapeutics plc (AIM: SLN), a leading international RNAi therapeutics company, is pleased to note that its partner, Quark Pharmaceuticals, Inc. ("Quark"), has announced the grant of an option to Novartis to obtain an exclusive worldwide license to develop and commercialise QPI-1002, a p53 temporary inhibitor siRNA drug which incorporates Silence's AtuRNAi technology.

Quark is currently conducting a Phase II clinical trial of QPI-1002 for the prevention of acute kidney injury in patients undergoing cardiac surgery and for delayed graft function in kidney transplant patients.  Based on the announcement issued by Quark on 18 August 2010, and under the terms of Silence's agreement with Quark, Silence anticipates that its future milestone payments from this program could potentially exceed $65 million.    

Commenting on today's announcement, Phil Haworth, CEO of Silence, said: "We are delighted that Novartis has chosen to take this development option for QPI-1002.  This serves as further validation of Silence's leading AtuRNAi technology and we look forward to receiving the significant milestones as the development of QPI-1002 continues."

About Silence Therapeutics plc (www.silence-therapeutics.com)

Silence Therapeutics plc (AIM: SLN) is a leading global biotechnology company dedicated to the discovery, development and delivery of targeted, systemic RNA interference (RNAi) therapeutics for the treatment of serious diseases.  The company possesses multiple proprietary short interfering RNA (siRNA) delivery technology platforms including AtuPLEX™, a system that enables the functional delivery of siRNA molecules to targeted diseased tissues and cells, while increasing their bioavailability and intracellular uptake.  A second, complementary delivery technology known as PolyTran™ uses a libra
'/>"/>

SOURCE Silence Therapeutics plc
Copyright©2010 PR Newswire.
All rights reserved

Page: 1 2

Related biology technology :

1. National Ovarian Cancer Coalition and PureOlogy to Host First Annual NOCC and PureOlogys Walk to Break the Silence on Ovarian Cancer
2. Silence Therapeutics to Present at 12th Annual BIO CEO & Investor Conference
3. Silence Therapeutics Appoints New Vice President of Research
4. Silence Therapeutics Issued Novel RNAi Patent Covering High-Value Cancer Target in United States
5. Silence Therapeutics Expands RNAi Structural Modification IP Portfolio With Issuance of New U.S. Patent
6. Halozyme Therapeutics Reports 2008 Second Quarter Financial Results
7. Repair Stem Cell Institute Announces Industrys First Standards of Excellence for Global Stem Cell Treatment Centers to Protect Patients from Less-than-Competent Therapeutics
8. Amsterdam Molecular Therapeutics Reports Half Year Results 2008
9. BN ImmunoTherapeutics Announces Partnership With National Cancer Institute
10. Arno Therapeutics Announces Appointment of Brian Lenz, CPA as Chief Financial Officer
11. CV Therapeutics Announces Ranexa(R) Named Finalist for Prix Galien USA 2008 Award
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:3/3/2015)... /PRNewswire/ - BIOREM Inc. (TSXV: BRM) ("Biorem" or "the Company") today ... odour control projects in North America , the ... . "Bidding activity in 2015 continues to be robust" ... high volume year for bidding in 2014, we are pleased to ... orders reflect the organization,s renewed focus on select market segments where ...
(Date:3/3/2015)... 2015 Adaptive Biotechnologies announced today that ... Board of Director as Chair of the Audit Committee. ... Chad oversees all finance, treasury and accounting functions. Since ... finance, treasury and accounting functions, and led the finance ... 2013, he was named Puget Sound Business Journal,s CFO ...
(Date:3/3/2015)... Fried, Frank, Harris, Shriver & Jacobson LLP ... joined the Firm as a partner in the Intellectual ... York office. Mr. Lewis concentrates on patent ... other intellectual property and general litigation. A trained chemical ... plaintiffs and defendants in a range of technology-related sectors ...
(Date:3/3/2015)... -- Thingee Corporation, a software development company for the Life ... Adoption: Making Reps, Lives Easier" during the 2015 Synergistix ...  in Deerfield Beach, Florida , taking ... to learn how technology can help them do their ... audience for the Thingee presentation. ...
Breaking Biology Technology:Adaptive Biotechnologies adds Chad Cohen, Zillow Group CFO, to Board of Directors 2Leading Patent Attorney Jeffrey Lewis Joins Fried Frank's Intellectual Property Litigation Practice 2Leading Patent Attorney Jeffrey Lewis Joins Fried Frank's Intellectual Property Litigation Practice 3Thingee to present at 11th Annual Synergistix Users Conference 2
... A new hand-held medical device will help UK athletes ... upcoming sporting competitions. UK Sport, the UK,s high performance ... first organisation to use cutting edge technology developed by ... Elite athletes will be able to monitor various proteins ...
... MOUNTAIN VIEW, Calif., Dec. 9, 2010 The ... of rejuvenation biotechnologies in addressing age-related disease. This ... donation to SENS Foundation, a California-based non-profit organization ... access to rejuvenation biotechnologies which comprehensively address age-related ...
... ("China-Biotics" or "the Company"), (Nasdaq: CHBT ) ... in China, today announced that it has redeemed $25 ... for cash two days before the December 11, 2010 ... originally issued on December 11, 2007. The redemption price ...
Cached Biology Technology:Medical science helps UK athletes reach peak performance 2Medical science helps UK athletes reach peak performance 3Internet Entrepreneur Jason Hope Pledges Half a Million Dollars to SENS Foundation 2Internet Entrepreneur Jason Hope Pledges Half a Million Dollars to SENS Foundation 3China-Biotics Announces Redemption of $25 million in Senior Convertible Notes 2China-Biotics Announces Redemption of $25 million in Senior Convertible Notes 3
(Date:2/5/2015)... 3, 2015 Despite a lack of ... such as consumer electronics, automotive, storage and telecommunication ... technology (SMT) screen printers. Innovations in electronics and ... push the adoption curve up. Meanwhile, sale volumes ... glue dispensers are indispensable in the production of ...
(Date:1/22/2015)... , Jan. 13, 2015  Today, FreeWavz ( www.FreeWavz.com ... its crowdfunding campaign on Fundable, https://www.fundable.com/freewavz . ... of production capacity to meet customer demand. ... - http://photos.prnewswire.com/prnh/20150113/168790 Invented ...
(Date:1/22/2015)... Jan. 20, 2015 NXT-ID, Inc. (NASDAQ: NXTD and ... reports on the recent success of the Wocket™ smart wallet at CES ... smart wallet was named as one of the "11 Hot Products at ... Products Launched At CES So Far" by Newseveryday.com and "The top 10 ...
Breaking Biology News(10 mins):End-user Demand Spurs Global SMT Screen Printers and Glue Dispensers Market 2End-user Demand Spurs Global SMT Screen Printers and Glue Dispensers Market 3FreeWavz Launches on Fundable to Drive Speed-to-Market in 2015 2CES Response for NXT-ID's Wocket Smart Wallet Kicks Off 2015 2CES Response for NXT-ID's Wocket Smart Wallet Kicks Off 2015 3
... NY, February 20, 2014A new era of manufacturing is upon ... are set to usher in the next generation of industrial ... groundbreaking new technology, Mary Ann Liebert, Inc., publishers has released ... journal 3D Printing and Additive Manufacturing ( 3DP ...
... NY, February 20, 2014A new era of manufacturing is upon ... are set to usher in the next generation of industrial ... groundbreaking new technology, Mary Ann Liebert, Inc., publishers has released ... journal 3D Printing and Additive Manufacturing ( 3DP ...
... highly sexed mouse-like marsupial in Queensland,s Springbrook National Park., ... of the World Heritage Area.,It,s the third new species ... research team has discovered in the past two years, ... the rare, Black-tailed Antechinus was a separate species when ...
Cached Biology News:3-D Printing and Additive Manufacturing: Preview issue of groundbreaking peer-reviewed journal now available 23D Printing and Additive Manufacturing 2Newly discovered marsupial the victim of fatal attraction 2
... coil, Trans-Blot cell, provides temperature ... and extended electrophoretic transfer (blotting) ... cell. Use of the super ... an external water recirculator, which ...
Criterion staining and blotting trays are plastic trays designed for staining one or two Criterion gels or performing western blot detection. The trays have a working capacity of up to 500 ml. Suppli...
... incorporating a wide range of next-generation features ... a new standard for flexible laboratory solutions. ... including pipetting, dilution, dispensing, and integrations ... as powerful and flexible as it is ...
... Biomek FX provides complete solutions ... With 96-, 384-, and ... in either single or dual ... offers maximum speed and flexibility ...
Biology Products: