Navigation Links
Signal Genetics Announces Publication of BreastPRS™ Validation Study with Weill Cornell Medical College, New York
Date:7/23/2013

New York, NY (PRWEB) July 23, 2013

Signal Genetics today announced that the results of a retrospective Weill Cornell validation study of BreastPRS, a novel series of prognostic and molecular profiling algorithms for breast cancer, has been published in the medical journal ‘Breast Cancer Research and Treatment’. Signal Genetics, LLC, is a privately held molecular diagnostic company based in New York, NY and Little Rock, AR.

Ryan Van Laar, Ph.D., Head of Bioinformatics & New Product Development at Signal Genetics said “We are excited about the results of this independent study, which determines that our BreastPRS test has the potential to provide physicians improved breast cancer prognostication and more critical personalized information. It is now much more than a viable alternative.”

The publication is titled “BreastPRS is a gene expression assay that stratifies intermediate-risk Oncotype DX patients into high- or low-risk for disease recurrence.”[1]. The study was performed by re-analyzing breast cancer tissue from 246 Weill Cornell patients whose tissue had previously been analyzed with Oncotype DX® by Genomic Health® (CA) . Gene expression analysis and BreastPRS calculations were performed in Signal Genetics’ CLIA-certified laboratory in Little Rock, AR.

The correlation between recurrence score and risk groups generated from the Oncotype DX and BreastPRS methods was highly statistically significant (P < 0.0001). Notably BreastPRS was found to reclassify Oncotype DX intermediate-risk patients into two groups with significant differences in recurrence free survival, potentially offering physicians an alternative method of breast cancer prognostication, which includes molecular grade and molecular subtyping algorithms to provide a comprehensive personalized analysis of each patient’s disease.

BreastPRS has also been used by researchers at the Windber Research Institute (Wind
'/>"/>

Source: PRWeb
Copyright©2012 Vocus, Inc.
All rights reserved

Page: 1 2

Related biology technology :

1. Needle beam could eliminate signal loss in on-chip optics
2. Physicists skirt thermal vibration, transfer optical signal via mechanical oscillator
3. Laser-like photons signal major step towards quantum Internet
4. Researchers identify signals that direct the immune system to reject a transplanted organ
5. Signal-Health Develops Easy Checklist to Identify Possible Sweating Issues in Horses
6. Signal Genetics LLC Announces Update to MyPRS™ Gene Expression Profiling Assay for Multiple Myeloma
7. Interleukin Genetics Reports Third Quarter 2011 Financial Results
8. Metamark Genetics Signs Collaboration Agreement on Novel Therapeutic Targets with Janssen Biotech
9. Ambry Genetics Launches Illumina MiSeq Next-Gen Sequencing Services
10. Cytogenetics - Technologies, Markets and Companies
11. deCODE Genetics, in Collaboration with Academic Colleagues, Discovers Three Variants in the Sequence of the Human Genome that Affect the Risk of Thyroid Cancer
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:11/24/2014)... , Nov. 24, 2014  Last week, Representatives ... Butterfield (D-NC) took a bold bipartisan step ... introducing the OPEN Act. Original co-sponsors of the ... The Act will incentivize drug makers and innovators ... diseases and pediatric cancers, which opens the door ...
(Date:11/24/2014)... BELLINGHAM, Washington, USA (PRWEB) November 23, 2014 ... the dynamic field of optics and photonics is now available ... no or very low cost. SPIE, the international society ... making access to the complete SPIE Digital Library ... a subsidized price. , “Light-based technologies are integral to all ...
(Date:11/24/2014)... 24, 2014  Spherix Incorporated (Nasdaq: ... the fostering and monetization of intellectual property, today ... Ltd.,  Case No. 3:13-cv-03494-M and  Spherix v. Uniden ... in the United States District Court for the ... On November 21, 2014 the ...
(Date:11/22/2014)... 21, 2014 During his lifetime Richard ... need to surround himself with great people and take ... his friends often marveled at his extraordinarily courageous attitude ... life and -- even with his death impending—that’s how ... disease that would ultimately take his life. , Carrying ...
Breaking Biology Technology:OPEN Act Introduced to Repurpose Drugs for Rare Diseases 2SPIE Digital Library Now Available to High Schools, Two-Year Colleges at No or Low Cost 2Markman Hearing Held as Scheduled in VTech and Uniden Cases 2Sherry Sharp, Wife of CarMax Founder, Richard Sharp, Accepts Seat on Board of Cure Alzheimer’s Fund 2Sherry Sharp, Wife of CarMax Founder, Richard Sharp, Accepts Seat on Board of Cure Alzheimer’s Fund 3
... Neurognostics, Inc ., a Wisconsin company specializing ... announced today that the Food and Drug Administration (FDA) ... its trademarked MindState fDAD. MindState fDAD had previously ... acquisition device. The Special 510(k) allows Neurognostics to enhance ...
... Merge eMed , a Merge Healthcare ... company, today announced the release of Cedara I-ReadMammo ... mammography workstation software product is designed to help ... in adopting digital mammography. , ,I-ReadMammo was ...
... happen. In a country that invented take out food, that is ... is perpetually in motion, it was inevitable that work and indeed ... ten years, the place where knowledge work happens has shifted from ... deck, in a subway car, walking down the street or of ...
Cached Biology Technology:Who moved the workplace? 2Who moved the workplace? 3Who moved the workplace? 4
(Date:11/4/2014)... In nature, the right amount of death at the ... density, according to new research that could help in ... wildlife stocks. , In a paper in the journal ... University researcher and European colleagues conclude that the kind ... a loss of individuals, or mortality, depends on the ...
(Date:11/4/2014)... examining only marketing directed at children on the ... found that the majority of black, middle-income and ... tactics. , Authored by Arizona State University researcher ... the first to examine the use of child-directed ... food restaurants and its relationship to demographics. It ...
(Date:11/4/2014)... , Nov. 4, 2014   Neurotechnology ... today announced that the latest version of its ... the Ongoing MINEX evaluation organized by ... fingerprint algorithms using the INCITS 378 fingerprint standard ... requirement in public tenders in the ...
Breaking Biology News(10 mins):When less is more: Death in moderation boosts population density in nature 2Fast food marketing for children disproportionately affects certain communities 2Fast food marketing for children disproportionately affects certain communities 3Neurotechnology Places Second in Ongoing MINEX Ranking for Fingerprint Matching Algorithms 2Neurotechnology Places Second in Ongoing MINEX Ranking for Fingerprint Matching Algorithms 3
... technology that uses "green" chemistry to help microbes break ... has earned kudos from the editors of Environmental Protection ... the Year. , The technology, which was invented by ... and licensed and manufactured by EOS Remediation, LLC, a ...
... , This release is available in French ... has played a role in the development of the many ... dart frog, according to a study that will be published ... University of Montreal biologist Mathieu Chouteau. The researcher,s methodology was ...
... James Wilkinson at the University of Southampton,s Optoelectronics ... Council (ERC) Advanced Grant to realise tools for ... analysis in water pollution and food safety. , ... biophotonics research in near- to mid-infra-red devices. ...
Cached Biology News:Predators drive the evolution of poison dart frogs' skin patterns 2
More cell-permeant than acridine orange....
Anti-rat Ig HRP detection kit...
One bottle containing 30 ml of protein solution and 0.1% sodium azide....
Used in May-Grunwald Giemsa stain....
Biology Products: