Navigation Links
Sigma-Aldrich Joins Phase 2 of The RNAi Consortium to Validate shRNA Libraries
Date:5/7/2008

RNAi reagents guaranteed to work out of the box. Sigma-Aldrich will also expand its program to promote and educate the research community about the multiple applications of RNAi technology by providing educational tools and forums.

"Sigma-Aldrich is committed to the development of RNAi technology. Through our collaboration with TRC2, we're producing the most highly validated shRNA libraries available to the research community," said Dave Smoller, President of Sigma-Aldrich's Research Biotech Business Unit. "By making these tools available to researchers worldwide, Sigma-Aldrich is facilitating advanced disease and drug discovery research."

Lentiviral-based shRNA libraries enable researchers to study gene function and disease, both in standard cell lines and recognized difficult cell types such as primary, non-dividing, growth-arrested or terminally differentiated cells. Such cell lines are typically not amenable to standard transfection or genomic integration by other viral delivery systems, but they may be transduced efficiently with lentiviral particles.

"Over the coming years, The RNAi Consortium intends to build upon its successes with shRNA to facilitate loss-of-function genetic screens in mammalian cells," said David Root, Director of the RNAi Platform at the Broad Institute of MIT and Harvard and project leader for TRC2. "The existing TRC library has already proven highly effective for systematic viral-delivery RNAi screening. TRC2 will generate significant further improvements to the library and its applications."

The current MISSION(R) shRNA clone libraries comprise a comprehensive collection of more than 160,000 pre-cloned lentiviral-based shRNA vector constructs targeting more than 16,000 human genes (MISSION TRC-Hs1.0) and 16,000 mouse genes (MISSION TRC-Mm1.0). For more information about the MISSION(R) shRNA clone collections, please visit us online at http://www.sigma.com/tr
'/>"/>

SOURCE Sigma-Aldrich
Copyright©2008 PR Newswire.
All rights reserved

Page: 1 2 3

Related biology technology :

1. Sigma-Aldrich to Present at the Baird 2008 Growth Stock Conference on Tuesday, May 13, 2008
2. Sigma-Aldrich to Present at the Bank of America 2008 Healthcare Conference on Tuesday, May 13, 2008
3. Sigma-Aldrich Announces the Integration of Riedel-De Haen Into Core Product Brands
4. Sigma-Aldrich (Nasdaq: SIAL) Raises 2008 Diluted EPS Forecast by $.05 to $2.57-$2.67. Reports Q1 2008 Diluted EPS Up 14.3%; Sales Gain of 14.9%.
5. Sigma-Aldrich Corporation 1st Quarter 2008 Earnings Conference Call
6. Sigma-Aldrich Partners With Sunset Molecular Discovery to Expand Your Favorite Gene Search Tool
7. Sigma-Aldrich To Hold Annual Business Review
8. Sigma-Aldrich, Oxford BioMedica and Open Biosystems Settle Patent Dispute Over Use of LentiVector Technology in Research Reagents
9. Sigma-Aldrich and MorphoSys Enter Into a Collaboration and Licensing Agreement for Recombinant Research Antibodies
10. Sigma-Aldrich Names Helge Bastian New VP of Global Marketing for Research Biotech
11. Sigma-Aldrich Announces New Prestige Antibodies(TM) Line for Proteomics and Cell Biology Researchers
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:10/20/2014)... 20, 2014 Mapp Biopharmaceutical,s valiant effort ... therapeutic to fight the Ebola outbreak will make ... the production of pharmaceuticals can be, according to ... that while some may be taken aback by ... with industry knowledge are well aware of the ...
(Date:10/20/2014)... Inc. (NASDAQ: GNVC ) today announced the retirement ... of directors effective on October 24, 2014.   Dr. Horovitz joined ... chairman from June 2006 to November 2013.  During his tenure, ... Audit Committees of the board.  "We deeply ... to GenVec, and its stockholders," said Wayne T. Hockmeyer ...
(Date:10/19/2014)... The Latin American hardware encryption display market ... with analysis and forecast of revenue. This market was ... to reach $2,366.8 million by 2018, at a CAGR ... the TOC of the Latin American hardware encryption market ... provided. It also provides a glimpse of the segmentation ...
(Date:10/19/2014)... October 19, 2014 The Asia-Pacific Speech ... market in Asia-Pacific with analysis and forecast of revenue. ... in 2014 to $208 million by 2019, at a ... to 2019. , Browse through the TOC of the ... of the in-depth analysis provided. It also provides a ...
Breaking Biology Technology:Kalorama: ZMapp Highlights Need For Faster Biopharmaceutical Production 2Kalorama: ZMapp Highlights Need For Faster Biopharmaceutical Production 3Zola P. Horovitz To Retire From GenVec Board 2The Latin American hardware encryption display market is expected to reach $2,366.8 million by 2018 - New Report by MicroMarket Monitor 2The Latin American hardware encryption display market is expected to reach $2,366.8 million by 2018 - New Report by MicroMarket Monitor 3The Asia-Pacific Speech Analytics market is estimated to reach $208 million by 2019 - New Report by MicroMarket Monitor 2The Asia-Pacific Speech Analytics market is estimated to reach $208 million by 2019 - New Report by MicroMarket Monitor 3The Asia-Pacific Speech Analytics market is estimated to reach $208 million by 2019 - New Report by MicroMarket Monitor 4
... At an Amgen (Nasdaq: AMGN ),meeting of ... City,today, several members of its senior management team outlined ... -- including the,experimental bone drug denosumab -- growing in-line ... Amgen had two blockbuster products and today we have ...
... Nov. 7 InterMune, Inc.,(Nasdaq: ITMN ) today ... President of InterMune, will present at Deutsche,Bank,s 2008 Biotech ... EST., To access a live audio webcast of ... to the investor relations page of InterMune,s,corporate website at ...
... 7 NeoGenomics, Inc.,(OTC Bulletin Board: NGNM) announced ... will present at the Rodman & Renshaw,10th Annual ... at,the New York Palace Hotel in New York ... microcap public life sciences and biotech companies.,Gasparini and ...
Cached Biology Technology:Amgen Positioned to Deliver Attractive Growth Over Next Five Years 2Amgen Positioned to Deliver Attractive Growth Over Next Five Years 3Amgen Positioned to Deliver Attractive Growth Over Next Five Years 4Amgen Positioned to Deliver Attractive Growth Over Next Five Years 5Amgen Positioned to Deliver Attractive Growth Over Next Five Years 6NeoGenomics to Present at the Rodman & Renshaw Healthcare Conference on November 10 2
(Date:10/16/2014)... Researchers at William and Mary,s Virginia Institute of ... from the Environmental Protection Agency to identify the ... and to develop tools to help local governments ... project depends critically on a dataset of tidal-marsh ... 1970s. Only with this historical baseline can today,s ...
(Date:10/16/2014)... respiratory tract infections and worldwide claims the lives ... and Ghent University have succeeded in developing a ... infection. , Xavier Saelens (VIB/UGent): "We discovered ... for the development of a novel approach to ... in numerous small children and elderly people." , ...
(Date:10/15/2014)... risk from strains of influenza virus increases with the ... become complacent that the most substantial threats have been ... pandemics arise when a new virus strain – against ... spreads in the human population. There have been five ... of which – the 1918 Spanish Flu – cost ...
Breaking Biology News(10 mins):EPA grant will help localities conserve headwater wetlands 2EPA grant will help localities conserve headwater wetlands 3New perspectives for development of an RSV vaccine 2Scientists 'must not become complacent' when assessing pandemic threat from flu viruses 2
... The average American child from age 8 to 18 ... have a TV in the bedroom and about one-third of ... that TV viewing time during childhood and adolescence continues into ... team from the Pennington Biomedical Research Center in Baton Rouge, ...
... on environmental issues such as climate change, deforestation, and ... But new research suggests that environmental messages framed in ... terms of fending off threats to the "purity" and ... to narrow the partisan gap. A study from ...
... deforestation and toxic waste, the assumption has been that conservative ... the University of California, Berkeley, suggests that such viewpoints can ... to be better stewards of the land are couched in ... of Earth and our bodies. A UC Berkeley study ...
Cached Biology News:Bedroom TV viewing increases risk of obesity in children 2Messages that speak to conservatives' morals narrow partisan gap on environment 2Messages that speak to conservatives' morals narrow partisan gap on environment 3Conservatives can be persuaded to care more about the environment 2Conservatives can be persuaded to care more about the environment 3
Goat polyclonal to HNF4 ( Abpromise for all tested applications). Antigen: Synthetic peptide: RLSKTLVDMDMADY (Human) N terminal. Entrez GeneID: 3172 Swiss Protein ID: P41235...
ATGL Antibody Shipping Temperature: HOT Storage Temperature: -20C...
Rabbit polyclonal to SpUlp2 ( Abpromise for all tested applications). Antigen: Synthetic peptide: SNNERQSLSSGSND, corresponding to amino acids 622-635 of Schizosaccharomyces pombe SpUlp2...
Lipid Phosphate Phosphohydrolase 2...
Biology Products: