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Sigma-Aldrich (Nasdaq: SIAL) Annual Sales Surpass $2 Billion Mark.
Date:2/12/2008

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payments 7.8 4.3

Net cash used in financing activities (212.0) (156.2)

Effect of exchange rate changes on cash 7.8 5.4

Net change in cash and cash equivalents 63.8 75.2

Cash and cash equivalents at January 1 173.8 98.6

Cash and cash equivalents at December 31 $237.6 $173.8

SIGMA-ALDRICH CORPORATION

Supplemental Financial Information - (Unaudited)

Sales Growth by Business Unit

Three Months

Ended December 31, 2007

Currency Adjusted

Reported Benefit Acquisition (Organic)

Research Essentials 11.8% 6.8% -% 5.0%

Research Specialties 15.5% 7.8% -% 7.7%

Research Biotech 11.3% 6.9% -% 4.4%

SAFC 16.8% 5.6% 8.0% 3.2%

Total 14.6% 6.8% 2.3% 5.5%

Twelve Months

Ended December 31, 2007

Currency Adjusted

Reported Benefit Acquisition (Organic)

Research Essentials 9.2% 4.6% -% 4.6%

Research Specialties 13.6% 5.3% -% 8.3%

Research Biotech 8.1% 4.4% -% 3.7%

SAFC 19.1% 4.4% 7.6% 7.1%

Total 13.4% 4.8% 2.1% 6.5%
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SOURCE Sigma-Aldrich Corporation
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