Navigation Links
Sheffield scientists shine a light on the detection of bacterial infection
Date:12/12/2011

Researchers at the University of Sheffield have developed polymers that fluoresce in the presence of bacteria, paving the way for the rapid detection and assessment of wound infection using ultra-violet light.

When contained in a gel and applied to a wound, the level of fluorescence detected will alert clinicians to the severity of infection. The polymers are irreversibly attached to fragments of antibiotics, which bind to either gram negative or gram positive bacteria both of which cause very serious infections informing clinicians as to whether to use antibiotics or not, and the most appropriate type of antibiotic treatment to prescribe. The team also found that they could use the same gels to remove the bacteria from infected wounds in tissue engineered human skin.

Speaking at the British Science Festival today (15 September), Professor Sheila MacNeil, an expert in tissue engineering and wound healing, explains: "The polymers incorporate a fluorescent dye and are engineered to recognise and attach to bacteria, collapsing around them as they do so. This change in polymer shape generates a fluorescent signal that we've been able to detect using a hand-held UV lamp."

"The availability of these gels would help clinicians and wound care nurses to make rapid, informed decisions about wound management, and help reduce the overuse of antibiotics," says project lead Dr Steve Rimmer.

Currently, determining significant levels of bacterial infection involves swabbing the wound and culturing the swabs in a specialist bacteriology laboratory with results taking several days to be available. The team is confident that its technology can ultimately reduce the detection of bacterial infection to within a few hours, or even less.

The research has already demonstrated that the polymer (PNIPAM), modified with an antibiotic (vancomycin) and containing a fluorescent dye (ethidium bromide), shows a clear fluorescent signal when
'/>"/>

Contact: Jo Kelly
jo@campuspr.co.uk
44-113-357-2100
University of Sheffield
Source:Eurekalert

Page: 1 2

Related biology technology :

1. Sheffield scientists shine a light on the detection of bacterial infection
2. Sheffield Bio-Science Adds Chemically Defined Media Supplements to Product Portfolio
3. Singapore scientists lead human embryonic stem cell study
4. Scientists defuse the Vietnam time bomb
5. Scientists carve nanowires out of ultrananocrystalline diamond thin films
6. Berkeley Lab scientists develop new tool for the study of spatial patterns in living cells
7. Shaken, not stirred: Berkeley lab scientists spy molecular maneuvers
8. Using new technique, scientists uncover a delicate magnetic balance for superconductivity
9. Scientists create computing building blocks from bacteria and DNA
10. Scientists determine alternative insecticide dramatically reduces malaria transmission
11. Scientists take up golf to prove long-standing theory of cell stickiness
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:9/19/2014)... Minnesota (PRWEB) September 19, 2014 ... related food industries will gather October 5–8, 2014, ... the Rhode Island Convention Center in Providence, Rhode ... feature the work of food scientists, chemists, microbiologists, ... control, and food production management. To date, 1,000 ...
(Date:9/19/2014)... -- , The first grants awarded to ... (ESPE) Meeting  Investment supports innovative projects for ... field of growth  , EMD Serono, a ... , today announced the first recipients of the Grant ... announced during a Satellite Symposium organized by EMD Serono ...
(Date:9/18/2014)... 2014 Bipartisan passage this week by ... to stimulate development and commercialization of new technologies and ... leaders of SPIE, the international society for optics ... and Innovation (RAMI) Act, now moves to the full ... they are optimistic that it will win passage there ...
(Date:9/18/2014)... LONDON , Sept. 18, 2014 ... near-patient testing, is performed outside a clinical laboratory. ... hence in administrating appropriate treatments and medication. POCT ... and prevalence of lifestyle diseases such as diabetes, ... and user-friendly. POCT devices are standardized to minimize ...
Breaking Biology Technology:Latest Research on Cereal Grain Quality, Health Benefits and Food Production to be Presented During the AACC International Annual Meeting 2Latest Research on Cereal Grain Quality, Health Benefits and Food Production to be Presented During the AACC International Annual Meeting 3EMD Serono Awards Grant for Growth Innovation (GGI) for the First Time 2EMD Serono Awards Grant for Growth Innovation (GGI) for the First Time 3House passage of high-tech manufacturing bill is move toward stronger economy, say SPIE leaders 2House passage of high-tech manufacturing bill is move toward stronger economy, say SPIE leaders 3POCT Market in China 2014-2018 2
... of online usability challenged businesses to better meet the ... Wednesday at a Web usability conference titled Are Your ... conference, which was hosted by the Madison chapter ... topics ranging from e-course standards to designing Web pages ...
... choice! , ,So what does government have to do ... -- I meant governance ! Theres ... that government caused governance or, at least, the recent emphasis on ... -- Enron, Worldcom, Tyco -- have reduced the publics trust in ...
... Wis. startups, biotech , ,Entrepreneurship, nanotechnology and biomedical ... 1-4 in Madison and Milwaukee, giving substance to what ... Week. , , Tips for Entrepreneurs , ,Established ... Wisconsin Entrepreneurs Conference , which runs June 1-2 at ...
Cached Biology Technology:Special needs addressed at Web Usability Conference 2Part 4 Project Performance Get on the path to continuous improvement 2Part 4 Project Performance Get on the path to continuous improvement 3Doyles Entrepreneurs and Research week nears 2Doyles Entrepreneurs and Research week nears 3
(Date:9/18/2014)... 18, 2014 New research into the Crimean-Congo hemorrhagic ... severe hemorrhagic disease in humans similar to that caused ... CCHFV infection. This discovery has the potential to lead ... , The research, reported in a paper ... and conducted by scientists at the Texas Biomedical Research ...
(Date:9/18/2014)... No matter how many times it,s demonstrated, ... communicating creatures. , But by using a ... radically alter their behavior to suit their population. ... them are present, and act accordingly. , Once ... it may change from innocuous to pathogenic, or ...
(Date:9/18/2014)... researchers and their colleagues have built the first ... academic performance and behavioral trends. In other words, ... even if you don,t -- and how that ... students, happiness, stress, depression and loneliness to their ... general population for example, to monitor mental ...
Breaking Biology News(10 mins):Research milestone in CCHF virus could help identify new treatments 2Researchers study vital 'on/off switches' that control when bacteria turn deadly 2Researchers study vital 'on/off switches' that control when bacteria turn deadly 3New Dartmouth smartphone app reveals users' mental health, performance, behavior 2New Dartmouth smartphone app reveals users' mental health, performance, behavior 3New Dartmouth smartphone app reveals users' mental health, performance, behavior 4
... for colorectal cancer was reported today (Thursday, Oct. 24) ... in Boston. The interaction may shed light on the ... associated with consumption of red and processed meat, the ... relevant public health significance because diet is a modifiable ...
... operating principles of a genetic switch that cancer cells use ... the body. The study found that the on-off switch,s dynamics ... and "off." The extra setting both explains previously confusing experimental ... treatment. The study appears online this week in the ...
... breast cancer from families severely affected with the disease have ... vast majority of those patients were told that their gene ... genomics sequencing tools, the discovery of additional genes implicated in ... genetic testing for BRCA1 and BRCA2, it is now possible ...
Cached Biology News:Gene-diet interaction may help explain link between eating meat & colorectal cancer risk 2Gene-diet interaction may help explain link between eating meat & colorectal cancer risk 3Physicists decode decision circuit of cancer metastasis 2Physicists decode decision circuit of cancer metastasis 3Physicists decode decision circuit of cancer metastasis 4BROCA sequencing approach evaluates all 24 genes implicated in breast cancer 2BROCA sequencing approach evaluates all 24 genes implicated in breast cancer 3
RABBIT ANTI NEOPTERIN...
MOUSE ANTI SIMIAN VIRUS 5:FITC Immunogen: Simian virus 5...
... Breed • Dog serum is collected from fasted ... of age Available Anticoagulants: N-02: ... N-06: K2EDTA N-08: Potassium Oxalate ... Alsevers N-05: ACD N-07: ...
Collected from normal, healthy animals in carefully maintained standing herds of US orgin. Pricing: $45/unit for 1 - 10 units...
Biology Products: