Navigation Links
Self-assembled materials form mini stem cell lab
Date:3/27/2008

EVANSTON, Ill. --- Imagine having one polymer and one small molecule that instantly assemble into a flexible but strong sac in which you can grow human stem cells, creating a sort of miniature laboratory. And that sac, if used for cell therapy, could cloak the stem cells from the human bodys immune system and biodegrade upon arriving at its destination, releasing the stem cells to do their work.

Futuristic" Only in part. A research team from Northwestern Universitys Institute for BioNanotechnology in Medicine has created such sacs and demonstrated that human stem cells will grow in them. The researchers also report that the sacs can survive for weeks in culture and that their membranes are permeable to proteins. Proteins, even large ones, can travel freely across the membrane.

This new and unexpected mode of self-assembly, to be published March 28 in the journal Science, also can produce thin films whose size and shape can be tailored. The method holds promise for use in cell therapy and other biological applications as well as in the design of electronic devices by self-assembly, such as solar cells, and the design of new materials.

We started with two molecules of interest, dissolved in water, and brought the two solutions together, said Samuel I. Stupp, Board of Trustees Professor of Materials Science and Engineering, Chemistry and Medicine, who led the research.

We expected them to mix, but, much to our surprise, they formed a solid membrane instantly on contact. This was an exciting discovery, and we then proceeded to investigate why it happened. Understanding the surprising molecular mechanism was even more exciting.

One of the molecules is a peptide amphiphile (PA), small synthetic molecules that Stupp first developed seven years ago, which have been essential in his work on regenerative medicine. The other molecule is the biopolymer hyaluronic acid (HA), which is readily found in the human body, in places l
'/>"/>

Contact: Megan Fellman
fellman@northwestern.edu
847-491-3115
Northwestern University
Source:Eurekalert

Page: 1 2 3 4

Related biology technology :

1. Arrow International Files and Mails Definitive Proxy Materials
2. Advancements in Population Age and Technology Drive Future of Orthopedic Materials Market
3. DuPont and Plantic Technologies Announce Starch-Based Bio Materials Collaboration
4. National Stem Cell Holding Announces Patent Application for Newly Discovered Cellular Derived Biomaterials for Anti-Aging Applications
5. Novel gate dielectric materials: perfection is not enough
6. Biotechnology Needed to Help Meet Growing Global Needs for Food, Feed, Fuel and Materials, DuPont Chairman & CEO Says at World Food Prize
7. NanoMaterials Technology to Conduct Process Development Feasibility Study with US Based Emerging Pharmaceutical Company
8. MIT: Thermoelectric materials are 1 key to energy savings
9. Harland Medical Systems to Offer March Plasma Systems Surface Materials
10. Hybrid materials: Exciting interdisciplinary field offering future solutions for industry
11. Nanomaterials show unexpected strength under stress
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:8/29/2014)... SAN DIEGO, Aug. 29, 2014  Pfenex Inc. ... in the development of high-value and difficult to ... business update and reported financial results for the ... "With the successful completion of our initial public ... advance our biosimilar product candidates, derived from our ...
(Date:8/29/2014)... are based on electrons, but one of the most ... i.e. circuits based on light (photons) instead of electrons. ... a stream of single photons and control their direction. ... attempts to achieve this control, but now scientists at ... steady stream of photons emitted one at a time ...
(Date:8/29/2014)... (PRWEB) August 29, 2014 The ... $5.6 billion in 2019. It is expected to ... to 2019, and was valued at $1.8 billion ... by Transparency Market Research. , For more information ... http://www.transparencymarketresearch.com/companion-diagnostics-market.html . , The research report, titled “Companion ...
(Date:8/29/2014)... 29, 2014 According to a new market ... global orthobiologics market was valued at USD 3,754.6 million in ... 5,519.9million in 2019at a CAGR of 5.9% from 2013 to ... and above is afflicted by bone and joint disorders, and ... 2020. This has and will continue to increase the demand ...
Breaking Biology Technology:Pfenex Reports Second Quarter 2014 Results and Provides Business Update 2Pfenex Reports Second Quarter 2014 Results and Provides Business Update 3Pfenex Reports Second Quarter 2014 Results and Provides Business Update 4Pfenex Reports Second Quarter 2014 Results and Provides Business Update 5Pfenex Reports Second Quarter 2014 Results and Provides Business Update 6Pfenex Reports Second Quarter 2014 Results and Provides Business Update 7Pfenex Reports Second Quarter 2014 Results and Provides Business Update 8Breakthrough in light sources for new quantum technology 2Companion Diagnostics Market to Hit $5.6 Billion in 2019: Transparency Market Research 2Companion Diagnostics Market to Hit $5.6 Billion in 2019: Transparency Market Research 3Global Orthobiologics Market to Reach $5,519.9 Million by 2019: Transparency Market Research 2Global Orthobiologics Market to Reach $5,519.9 Million by 2019: Transparency Market Research 3
... used the electric fields generated by intersecting laser beams ... thereby creating 3-D arrays of optically induced crystals. ... structure of materials of biological interest, including bacteria, viruses ... is co-author of a research paper on the topic ...
... EIN News has been a world leader in industry news ... includes expanded coverage of science & technology. ... company is continuing a 15-year expansion of its services to ... decision makers who need quick and comprehensive access to information. ...
... principal at global management consulting firm ZS Associates, was named ... Magazine. Mitchell was recognized for directing his consulting team,s partnership ... a major, recent product launch. "I feel honored ... who has more than 10 years of experience with sales, ...
Cached Biology Technology:Lasers used to form 3-D crystals made of nanoparticles 2Science & Technology News Service Expands Coverage 2Managing Principal at ZS Associates Named One of Consulting Magazine's Top 25 Consultants of 2011 2
(Date:8/29/2014)... Until recently, little has been known about what ... international team of scientists, one of whom is a ... by showing that genes controlling the development of the ... rabbit domestication., The study was published Aug. 28 in ... questions. It is online at http://www.sciencemag.org/ ., The ...
(Date:8/29/2014)... climatic shifts over the last 120,000 years may ... team of researchers led by City College of ... new biodiversity metric called "phylogeographic endemism." , It ... within species is restricted in geographical space. , ... 14 other researchers from institutions in Brazil, Australia ...
(Date:8/29/2014)... available in German . ... the natural nitrogen cycle on Earth and in biological ... thought to depend on nitrite as their source of ... Daims, a microbiologist at the University of Vienna, has ... an alternative source of energy. The oxidation of hydrogen ...
Breaking Biology News(10 mins):New research reveals how wild rabbits were genetically transformed into tame rabbits 2New research reveals how wild rabbits were genetically transformed into tame rabbits 3CCNY team defines new biodiversity metric 2Hydrogen powers important nitrogen-transforming bacteria 2Hydrogen powers important nitrogen-transforming bacteria 3
... and medical professionals across the country gained a valuable ... approved the first hand-held device to detect life-threatening bleeding ... the Infrascanner, was initiated and funded by the Office ... device reveals intracranial hematomas soon after an injury, and ...
... Imagine you,re a hockey goalie, and two opposing players are ... forth. You,re aware of the linesman skating in on your ... the puck and the two approaching players. As the action ... "multi-tasking"? Are you splitting your focus of attention into multiple ...
... of Standards and Technology (NIST) has issued the world,s ... related to the soot in your fireplace or in ... source of single-wall carbon nanotubes, perhaps the archetype of ... and researchers a badly needed source of uniform and ...
Cached Biology News:Naval technology could be a lifesaver 2How do we split our attention? 2NIST releases first certified reference material for single-wall carbon nanotubes 2NIST releases first certified reference material for single-wall carbon nanotubes 3
... is the universal bioinformatics software that has ... The unique modular design of BioNumerics allows ... any type of data employed for the ... DNA fingerprints, 2-D protein gels, HPLC, VNTR, ...
Request Info...
Cultrex 3D Culture Matrix Rat Collagen I....
Cultrex 3D Culture Matrix BME....
Biology Products: