Navigation Links
Scientists learn how to 'out run damage' with imaging technique
Date:2/21/2012

VANCOUVER, CANADA - Over the decades X-ray crystallography has been fundamental in the development of many scientific fields. The method has revealed the structure and function of many biological molecules, including vitamins, drugs, proteins and nucleic acids such as DNA. However, in order to obtain good data, large single crystals are required. These are often nearly impossible to grow. There also is the problem that X-rays damage delicate biological samples.

"From the beginning, the resolution of images recorded by biologists has been limited by damage due to the radiation used," said physicist John C. H. Spence, a Regents' Professor in physics at Arizona State University. "But what happens if a pulse of imaging radiation is used that terminates before damage begins, yet contains sufficient photons to generate a useful scattering pattern?"

Indeed, results of such a method are being reported by Spence at the American Association for the Advancement of Science annual meeting in Vancouver, Canada. Spence presented his findings today (Feb. 17) during a special session on "Imaging and Controlling Molecular Dynamics with Ultrashort Laser Pulses."

Many in the scientific community didn't believe such a method could work. Yet, said Spence "The experiments of Henry Chapman's (University of California, Davis) group using lithographed structures and soft (i.e. long wavelength) X-rays had shown that if we could 'out-run the damage,' this might indeed be a useful path to damage-free imaging at atomic resolution. In my lab we were thinking about the data analysis, and building the hydrated protein-beam injector device, a bit like an ink-jet printer, to spray the molecules across an X-ray laser. This snap-shot method should eventually allow us to make movies of molecular machines at work."

Spence joined forces with Chapman and many collaborators to recently demonstrate serial snapshot femtosecond (10-15 of a second) diffraction (SFX) f
'/>"/>

Contact: jenny green
jenny.green@asu.edu
480-965-1430
Arizona State University
Source:Eurekalert

Page: 1 2

Related biology technology :

1. Clemson scientists put a (nano) spring in their step
2. City of Hope Helps KGI Launch New Management Training Program for Scientists
3. University of Pennsylvania scientists move optical computing closer to reality
4. Scientists grow nanonets able to snare added energy transfer
5. The National Cancer Institute Joins the Global Community of Scientists Now Using BIOMARKERcenter From Thomson Reuters
6. Scientists peel away the mystery behind golds catalytic prowess
7. SACHEM Launches 2-D HPLC e-Learning Program : New e-Learning Program Teaches Scientists How to Better Analyze and Prove Product Purity Through Greater Sensitivity and Precision in Identification of Trace Components
8. Vermillion and Stanford Scientists Receive Best Research Award From the PAD Coalition
9. Brewing better beer: Scientists determine the genomic origins of lager yeasts
10. Tengion Scientists Publish Positive Preclinical Findings With Neo-Organ Demonstrating Long-term Durability and Growth With Skeletal Maturation
11. CU scientists create worlds thinnest balloon -- just one atom thick
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:4/20/2015)... Sinovac Biotech Ltd. (Nasdaq: SVA), a leading ... unaudited financial results for the fourth quarter and full ... 2014 Financial Highlights(Compared to the fourth quarter 2013) ... of 11.4% from $22.9 million in the prior year ... pandemic influenza vaccine of $0.1 million in the fourth ...
(Date:4/17/2015)... , April 17, 2015  Centrillion ... a SBIR grant from the National Human ... Institutes of Health (NIH). The grant will ... in the development of breakthrough genomic technologies, ... specially fabricated substrates. Centrillion has been developing ...
(Date:4/17/2015)... , April 17, 2015  US-Australian drug discovery company, ... Memorandum of Understanding with the Feinstein Institute for ... York to collaborate with the objective ... The collaboration brings together the drug discovery ... expertise of the Feinstein Institute in neurosciences and ...
(Date:4/16/2015)... and OSAKA, Japan ... Cell Research Application (CiRA) of Kyoto University and ... they will work together to develop clinical applications ... as heart failure, diabetes mellitus, neurological disorders and ... Cell Applications" (T-CiRA) is designed to expedite multiple ...
Breaking Biology Technology:Sinovac Reports Unaudited Fourth Quarter and Full Year 2014 Financial Results 2Sinovac Reports Unaudited Fourth Quarter and Full Year 2014 Financial Results 3Sinovac Reports Unaudited Fourth Quarter and Full Year 2014 Financial Results 4Sinovac Reports Unaudited Fourth Quarter and Full Year 2014 Financial Results 5Sinovac Reports Unaudited Fourth Quarter and Full Year 2014 Financial Results 6Sinovac Reports Unaudited Fourth Quarter and Full Year 2014 Financial Results 7Sinovac Reports Unaudited Fourth Quarter and Full Year 2014 Financial Results 8Sinovac Reports Unaudited Fourth Quarter and Full Year 2014 Financial Results 9Sinovac Reports Unaudited Fourth Quarter and Full Year 2014 Financial Results 10Sinovac Reports Unaudited Fourth Quarter and Full Year 2014 Financial Results 11Sinovac Reports Unaudited Fourth Quarter and Full Year 2014 Financial Results 12Sinovac Reports Unaudited Fourth Quarter and Full Year 2014 Financial Results 13Sinovac Reports Unaudited Fourth Quarter and Full Year 2014 Financial Results 14Sinovac Reports Unaudited Fourth Quarter and Full Year 2014 Financial Results 15Sinovac Reports Unaudited Fourth Quarter and Full Year 2014 Financial Results 16Sinovac Reports Unaudited Fourth Quarter and Full Year 2014 Financial Results 17Sinovac Reports Unaudited Fourth Quarter and Full Year 2014 Financial Results 18Novogen and Feinstein Institute Join Forces to Find Effective Treatments for Brain Cancer 2Novogen and Feinstein Institute Join Forces to Find Effective Treatments for Brain Cancer 3Novogen and Feinstein Institute Join Forces to Find Effective Treatments for Brain Cancer 4Novogen and Feinstein Institute Join Forces to Find Effective Treatments for Brain Cancer 5Novogen and Feinstein Institute Join Forces to Find Effective Treatments for Brain Cancer 6CiRA and Takeda Enter 10-year Collaboration on iPS Cell Research 2CiRA and Takeda Enter 10-year Collaboration on iPS Cell Research 3
... DIEGO, Jan. 31 Cardium Therapeutics,(Amex: CXM ... definitive purchase,agreement with institutional and other accredited or ... common stock and warrants to purchase shares,of its ... closing, the,transaction will result in gross proceeds to ...
... MOUNTAIN VIEW, Calif., Jan. 31 Alexza,Pharmaceuticals, Inc. ... corporate,presentation will be webcast live during the 10th ... 11, 2008 at 1:15 p.m. Eastern Time., ... Hotel in New,York. To access the live presentation ...
... Calif., Jan. 22 Abaxis, Inc.,(Nasdaq: ABAX ), ... scheduled a conference call to discuss its,financial results for ... 2007. The call will be at 4:15 p.m. ET, ... 356-5706 or (706) 643-0580 to access the,conference call, or ...
Cached Biology Technology:Cardium Announces $5.3 Million Registered Direct Offering 2Cardium Announces $5.3 Million Registered Direct Offering 3Cardium Announces $5.3 Million Registered Direct Offering 4Alexza's Corporate Presentation to be Webcast at the 10th Annual BIO CEO & Investor Conference 2Abaxis to Report Third Quarter Fiscal 2008 Financial Results Thursday, January 31, 2008 2
(Date:4/10/2015)... 2015 Research and Markets ( ... "Security Competitive Profiles - NEC" report to their ... NEC will continue to supply a range of IT ... a company focus on the development of a Big ... opportunities in the Asia-Pacific region ...
(Date:4/2/2015)... BETHESDA, Md. , April 2, 2015 ... Salt Lake City , the American ... election of five new directors to its Board.  Members ... for the ACMG and for forming and advancing its ... the medical genetics profession. "It,s an eventful ...
(Date:3/31/2015)...  Elephant Talk Communications Corp. (NYSE MKT: ETAK) ("Elephant ... Defined Network Architecture (ET Software DNA® 2.0) platforms and ... $20.4 million for the year ended December 31, 2014 ... year ended December 31, 2013. At ... its multi-year transition away from its legacy landline business ...
Breaking Biology News(10 mins):NEC Security Competitive Profile 2015 2American College of Medical Genetics and Genomics Announces New Board Members: Dr. Louanne Hudgins is ACMG President-Elect 2American College of Medical Genetics and Genomics Announces New Board Members: Dr. Louanne Hudgins is ACMG President-Elect 3American College of Medical Genetics and Genomics Announces New Board Members: Dr. Louanne Hudgins is ACMG President-Elect 4American College of Medical Genetics and Genomics Announces New Board Members: Dr. Louanne Hudgins is ACMG President-Elect 5American College of Medical Genetics and Genomics Announces New Board Members: Dr. Louanne Hudgins is ACMG President-Elect 6American College of Medical Genetics and Genomics Announces New Board Members: Dr. Louanne Hudgins is ACMG President-Elect 7American College of Medical Genetics and Genomics Announces New Board Members: Dr. Louanne Hudgins is ACMG President-Elect 8Elephant Talk Reports 2014 Fourth Quarter and Year End Financial Results 2Elephant Talk Reports 2014 Fourth Quarter and Year End Financial Results 3Elephant Talk Reports 2014 Fourth Quarter and Year End Financial Results 4Elephant Talk Reports 2014 Fourth Quarter and Year End Financial Results 5Elephant Talk Reports 2014 Fourth Quarter and Year End Financial Results 6
... (NTU) has received the prestigious Faculty of Medicine Fellowship ... sciences. The Fellowship was awarded to Prof Boey ... Imperial College,s Faculty of Medicine, in recognition of his ... to the development of the Lee Kong Chian School ...
... and Stroke (NINDS), part of the National Institutes of ... Center for Biomedical Imaging Statistics at Emory,s Rollins School ... biomarker research in Parkinson,s disease to identify non-invasive imaging ... biochemistry. Led by F. DuBois Bowman, PhD, associate ...
... affect the severity of kidney disease brought on by ... Professor Wei Jia at the University of North Carolina ... Nicholson at Imperial College London. In 2008, nearly ... on by supplies of powdered milk deliberately contaminated with ...
Cached Biology News:NTU Provost receives prestigious Imperial College fellowship joining the ranks of top UK scientists 2NTU Provost receives prestigious Imperial College fellowship joining the ranks of top UK scientists 3NIH funds research to identify Parkinson's biomarkers 2NIH funds research to identify Parkinson's biomarkers 3Gut microbes could determine the severity of melamine-induced kidney disease 2
IHC Detection Kit (Broad Spectrum AEC)....
...
... Modification Services ,,GenScript offers many ... and antibody fragmentation. Labeling antibodies with ... visualization and quantitation of the target ... preferable to use only the antigen-binding ...
Attoglow Western Blot Enhancing Kit contains Millennium Enhancer which can significantly boost Western blot signals, and is compatible with other enhancing mechanisms to achieve multiplied enhancing ...
Biology Products: