Navigation Links
Scientists identify mammal model of bladder regeneration
Date:10/25/2012

WINSTON-SALEM, N.C. While it is well known that starfish, zebrafish and salamanders can re-grow damaged limbs, scientists understand very little about the regenerative capabilities of mammals. Now, researchers at Wake Forest Baptist Medical Center's Institute for Regenerative Medicine report on the regenerative process that enables rats to re-grow their bladders within eight weeks.

In PLOS ONE, a peer-reviewed, online publication, the scientists characterize this unique model of bladder regeneration with the goal of applying what they learn to human patients.

"A better understanding of the regenerative process at the molecular and cellular level is a key to more rapid progress in applying regenerative medicine to help patients," said George Christ, Ph.D., senior researcher and professor of regenerative medicine at Wake Forest Baptist.

In a previous study by Christ's team, research in rats showed that when about 75 percent of the animals' bladders were removed, they were able to regenerate a complete functional bladder within eight weeks. The current study focused on how the regeneration occurs.

"There is very little data on the mechanisms involved in organ regeneration in mammals," said Christ. "To our knowledge, bladder regeneration holds a unique position there is no other mammalian organ capable of this type of regeneration."

The ability of the liver to grow in size when lobes are removed is sometimes referred to as regeneration, but this is a misnomer, said co-author Bryon Petersen, Ph.D., who was a professor of regenerative medicine at Wake Forest Baptist during the period the research occurred. Instead, through a proliferation of cells, the remaining tissue grows to compensate for the lost size. In contrast, the hallmark of true regeneration is following nature's "pattern" to exactly duplicate size, form and function, Petersen said.

"If we can understand the bladder's regenerative process,
'/>"/>

Contact: Karen Richardson
krchrdsn@wakehealth.edu
336-716-4453
Wake Forest Baptist Medical Center
Source:Eurekalert

Page: 1 2

Related biology technology :

1. Scientists build mechanically active DNA material
2. GenScript to Synthesize Yeast Genome with Johns Hopkins Scientists
3. Scientists report successful vaccine developed against deadly Nipah virus
4. Worlds smallest semiconductor laser created by University of Texas scientists
5. Scientists read monkeys inner thoughts
6. World record: Scientists from northern Germany produce the lightest material in the world
7. NineSigma Partners with Scientists Without Borders to Find New Sustainable Packaging for Micronutrient Powders that Combat Malnutrition
8. Scripps Research Institute scientists find easier way to make new drug compounds
9. Finding Brings Scientists One Step Closer To Parkinsons Drug
10. Stanford scientists spark new interest in the century-old Edison battery
11. Scientists gain understanding of self-cleaning gecko foot hair
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:11/24/2014)... (PRWEB) November 24, 2014 2014 ... Dihydrazide Industry is a professional and in-depth research ... Adipic Dihydrazide information, like its definition, classification, application, ... overview. This report covers the international market analysis, ... (such as the US, Europe, Asia, China, Japan ...
(Date:11/23/2014)... St. Francis, WI (PRWEB) November 23, 2014 ... based manufacturer and supplier of fine chemical ingredients ... industries announced the launch of its new website, ... a description of Apiscent Labs, clean design, easy ... qualities that make Apiscent Labs stand out. ...
(Date:11/22/2014)... 2014 CannLabs, Inc. (OTCQB: ... and scientific testing methodologies relating to cannabis, today announced ... line of credit from an existing stockholder of the ... secured this commitment from one of our existing stockholders,” ... “This capital will help accelerate our planned expansions into ...
(Date:11/22/2014)... (PRWEB) November 22, 2014 Respiratory ... simulate the proper management of life-like respiratory ailments ... lung devices . Grand Rapids-based, Michigan Instruments Inc. ... donate two of the respiratory simulation units to ... each. Grand Valley and Muskegon Community College are ...
Breaking Biology Technology:Adipic Dihydrazide Industry 2019 Research Forecasts on Worldwide, China Regions Now Available at ReportsnReports.com 2Adipic Dihydrazide Industry 2019 Research Forecasts on Worldwide, China Regions Now Available at ReportsnReports.com 3CannLabs Secures $750,000 Line Of Credit 2Michigan Instruments Donates Two Respiratory Simulation Training and Test Lung (TTL) Devices to Grand Valley State University 2Michigan Instruments Donates Two Respiratory Simulation Training and Test Lung (TTL) Devices to Grand Valley State University 3
... Calif., April 29, 2011 NeurogesX, Inc. (Nasdaq: ... novel pain management therapies, today announced that long time CEO ... of Directors has initiated a formal executive search for a ... been CEO of NeurogesX for more than eight years and ...
... a Kalamazoo-based company developing the next- generation of environmentally ... will serve as interim President and Chief Executive Officer. ... years of service leading to the development of breakthrough ... been just what Vestaron needed to get us to ...
... SAN DIEGO, April 28, 2011 Optimer Pharmaceuticals, Inc. ... from the DIFICID™ Phase 3 trials will be presented ... Place, Chicago, ILMay 7-10, 2011 Poster Presentation Information: Title: ... Treatment of Clostridium difficile Infection: ...
Cached Biology Technology:NeurogesX CEO Anthony DiTonno to Retire by Year End 2NeurogesX CEO Anthony DiTonno to Retire by Year End 3NeurogesX CEO Anthony DiTonno to Retire by Year End 4Vestaron Corporation Announces New Leadership 2Vestaron Corporation Announces New Leadership 3Optimer Pharmaceuticals and Clinical Investigators to Present Data at Upcoming Medical Meetings 2Optimer Pharmaceuticals and Clinical Investigators to Present Data at Upcoming Medical Meetings 3
(Date:11/5/2014)... RENO – Kelly Redmond has dedicated his career ... knowledge to a general audience. , As deputy ... Climate Center at Nevada,s Desert Research Institute, Redmond ... the management, application and dissemination of climate data ... Annual Fall Meeting in San Francisco on December ...
(Date:11/4/2014)... amount of death at the right time might actually ... research that could help in understanding animal populations, pest ... a paper in the journal Trends in Ecology ... colleagues conclude that the kind of positive population effect ... or mortality, depends on the size and developmental stage ...
(Date:11/4/2014)... examining only marketing directed at children on the ... found that the majority of black, middle-income and ... tactics. , Authored by Arizona State University researcher ... the first to examine the use of child-directed ... food restaurants and its relationship to demographics. It ...
Breaking Biology News(10 mins):Nevada climatologist to be honored at AGU Fall Meeting for lifetime of public outreach 2When less is more: Death in moderation boosts population density in nature 2Fast food marketing for children disproportionately affects certain communities 2Fast food marketing for children disproportionately affects certain communities 3
... certain proteins are made is crucial to the normal ... DNA is transcribed into RNA molecules and then translated ... not all genes code for proteins--some make RNA molecules ... control--the production of proteins. A new paper in PLoS ...
... Medicine researchers have discovered how new neurons born from ... the brain where they can replace old and dying ... can be specifically targeted to brain regions affected by ... Zhou and graduate student Kwan L. Ng in the ...
... around the world are breathing a sigh of ... of being harvested for their natural disease-fighting substances. ... which lives symbiotically inside the sea squirt, actually ... day be used in cancer treatment. , Despite ...
Cached Biology News:MicroRNAs play a big part in gene regulation - and evolution 2Researchers discover stem cell 'guide' that may be key for targeting neural stem cell treatments 2
... modular benchtop fume hood ventilates ... safe indoor release of exhaust. ... organic contaminants. Configurations are available ... options include final HEPA filter, ...
... modular cleanroom for biological safety labs ... cleanliness (to Class 10/ISO 3) and ... create ultra-smooth surfaces that are easy ... radius corners simplify cleaning. Unique double-wall ...
... the ability to quickly and accurately copy or ... perfect candidate for inclusion in these high speed ... with all the Cartesian products to allow integration ... to copy plates in seconds or reformat low ...
This modular benchtop fume hood ventilates and purifies chemical fumes, allowing safe indoor release of exhaust. Bonded charcoal filters remove most organic contaminants. Options include final HEPA f...
Biology Products: