Navigation Links
Scientists build 'mechanically active' DNA material
Date:10/25/2012

Artificial muscles and self-propelled goo may be the stuff of Hollywood fiction, but for UC Santa Barbara scientists Omar Saleh and Deborah Fygenson, the reality of it is not that far away. By blending their areas of expertise, the pair have created a dynamic gel made of DNA that mechanically responds to stimuli in much the same way that cells do. The results of their research were published online in the Proceedings of the National Academy of Sciences.

"This is a whole new kind of responsive gel, or what some might call a 'smart' material," said Saleh, associate professor of materials, affiliated with UCSB's Biomolecular Science and Engineering program. "The gel has active mechanical capabilities in that it generates forces independently, leading to changes in elasticity or shape, when fed ATP molecules for energymuch like a living cell."

Their DNA gel, at only 10 microns in width, is roughly the size of a eukaryotic cell, the type of cell of which humans are made. The miniscule gel contains within it stiff DNA nanotubes linked together by longer, flexible DNA strands that serve as the substrate for molecular motors.

"DNA gives you a lot more design control," said Fygenson, associate professor of physics and also affiliated with UCSB's BMSE program. "This system is exciting because we can build nano-scale filaments to specifications." Using DNA design, she said, they can control the stiffness of the nanotubes and the manner and extent of their cross-linking, which will determine how the gel responds to stimuli.

Using a bacterial motor protein called FtsK50C, the scientists can cause the gel to react in the same way cytoskeletons react to the motor protein myosinby contracting and stiffening. The protein binds to predetermined surfaces on the long linking filaments, and reels them in, shortening them and bringing the stiffer nanotubes closer together. To determine the gel's movement the scientists attached a tiny bead
'/>"/>

Contact: Melissa Van De Werfhorst
melissa@engineering.ucsb.edu
805-893-4301
University of California - Santa Barbara
Source:Eurekalert  

Page: 1 2 3

Related biology technology :

1. GenScript to Synthesize Yeast Genome with Johns Hopkins Scientists
2. Scientists report successful vaccine developed against deadly Nipah virus
3. Worlds smallest semiconductor laser created by University of Texas scientists
4. Scientists read monkeys inner thoughts
5. World record: Scientists from northern Germany produce the lightest material in the world
6. NineSigma Partners with Scientists Without Borders to Find New Sustainable Packaging for Micronutrient Powders that Combat Malnutrition
7. Scripps Research Institute scientists find easier way to make new drug compounds
8. Finding Brings Scientists One Step Closer To Parkinsons Drug
9. Stanford scientists spark new interest in the century-old Edison battery
10. Scientists gain understanding of self-cleaning gecko foot hair
11. WHEATON® Introduces a New Web Community for Scientists, Researchers, and Biopharmaceutical Packagers
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Scientists build 'mechanically active' DNA material
(Date:12/19/2014)... DUBLIN , Dec. 19, 2014 Research ... announced the addition of the "Technology Innovations ... their offering. http://photos.prnewswire.com/prnh/20130307/600769 ... Innovations in Smart Fabrics" offers a detailed assessment ... Key Findings: 1. ...
(Date:12/19/2014)... ME (PRWEB) December 18, 2014 Ed ... director of the Center for Excellence in the Neurosciences ... New England, has been selected as a member of ... is the first neuroscientist from Maine to receive this ... nonprofit organization supported entirely by the Dana Foundation. ...
(Date:12/19/2014)... The empty capsules market is experiencing ... and technological innovations in the empty capsules market. ... the growth of the empty capsules market. , ... Scope of Report , The report will enrich ... firms to gauge the pulse of the market ...
(Date:12/19/2014)... 18, 2014   ISN has released its ... Indicators publication series. With data aggregated from ... in 2013 within its online contractor management platform, ISNetworld, ... performance indicator (KPI) statistics. The ... publication is available in two industry specific volumes: ...
Breaking Biology Technology:Technology Innovations in Smart Fabrics (Technical Insights) 2UNE's Ed Bilsky Named Member of Dana Alliance for Brain Initiatives 2UNE's Ed Bilsky Named Member of Dana Alliance for Brain Initiatives 3Empty Capsules Market Hit to Reach $1,820 Million by 2019 - New Research Report by MarketsandMarkets 2Empty Capsules Market Hit to Reach $1,820 Million by 2019 - New Research Report by MarketsandMarkets 3Empty Capsules Market Hit to Reach $1,820 Million by 2019 - New Research Report by MarketsandMarkets 4ISN Releases Third Edition of US Contractor Health & Safety Performance Indicators Publication Series 2ISN Releases Third Edition of US Contractor Health & Safety Performance Indicators Publication Series 3
... have another chance to strengthen ties with Japan at ... Center. , ,Sponsored by the Japan External Trade ... an inside look into how Wisconsin biotech companies are ... traveled to Japan will talk about the difficulties and ...
... are available 24 hours a day now that a new ... , ,The Web site MusicMadeInMadison.com plays more than ... the Profits, Daedalus Burn, Infinite Helix and They Drive By ... site's goal is to help both the circulation of the ...
... and Human Services Secretary Mike Leavitt announced yesterday that ... will be formed to make recommendations for a nationwide ... , ,This news makes the Digital Healthcare Conference ... 9 at the Fluno Center in Madison, even more ...
Cached Biology Technology:Wisconsin biotechs plan Japan trade mission 2Preview: Electronic health records, tech choices explored at Digital Healthcare Conference 2Preview: Electronic health records, tech choices explored at Digital Healthcare Conference 3
(Date:12/17/2014)... Dec. 16, 2014 Research and Markets ... of the "Global Chemical Sensor Market 2015-2019" ... http://photos.prnewswire.com/prnh/20130307/600769 One major ... demand for medical sensors in biomedical applications. Chemical ... quick and correct diagnosis during surgical procedures. The ...
(Date:12/15/2014)... Dec. 12, 2014 Research and Markets ... of the "Global Facial Recognition Market 2015-2019" ... http://photos.prnewswire.com/prnh/20130307/600769 Facial recognition ... individuals. Facial recognition system measures the overall facial ... edges, mouth, and the distance between eyes. Facial ...
(Date:12/11/2014)... 2014 Research and Markets ... ( http://www.researchandmarkets.com/research/9ql3kr/biometrics_market ) has announced the addition of ... report to their offering. One ... adoption of multimodal biometric systems. Multimodal biometric systems ... for verification and identification purposes. This helps to ...
Breaking Biology News(10 mins):Global Chemical Sensor Market 2015-2019: Key Vendors are Abbott Laboratories, Bayer, Hoffmann La-Roche, Johnson & Johnson, NGK Spark Plugs and Robert Bosch 2Global Facial Recognition Market 2015-2019: Key Vendors are 3M Cogent, Cognitec Systems, NEC and Safran Group 2Global Facial Recognition Market 2015-2019: Key Vendors are 3M Cogent, Cognitec Systems, NEC and Safran Group 3Biometrics Market in India 2015-2019: Key Vendors are 3M Cogent, NEC, Safran and Suprema 2
... are spiritual, according to new research from Rice University. Though ... that spirituality is a separate idea one that more ... The research will be published in the June ... in-depth interviews with 275 natural and social scientists at elite ...
... human fungal infections caused by certain strains of Aspergillus ... treatments at an alarming rate, say scientists. University of ... a new test that can not only better diagnose ... resistance to azoles the class of drugs used to ...
... at Sam Houston State University and the University of Texas ... justice system in Houston to establish protocols to determine when ... , "This is a problem-solving project that seeks to determine ... William Wells, who is leading the research project at Sam ...
Cached Biology News:More than 20 percent of atheist scientists are spiritual 2Drug-resistance fears for deadly fungal disease 2Research to target untested rape kits 2Research to target untested rape kits 3
Request Info...
...
...
... purified Formulation: 50mM Tris-HCl, pH ... 0.2mM PMSF, 1mM benzamidine, 0.1% ... PP2A1 (Protein Phosphatase 2A1) partially ... sulfate precipitation, QSepharose,amino-hexyl agarose, Superdex ...
Biology Products: