Navigation Links
Scientists Find Way to Fast-Track Production of Stem Cells that Show Promise in Treating AMD
Date:4/18/2013

Durham, NC (PRWEB) April 18, 2013

Controlling the differentiation of human pluripotent stem cells is the goal of many laboratories, both to study normal human development and to generate cells for transplantation in treating various diseases and conditions. RPE (retinal pigmented epithelial) is one important cell type under investigation as it protects and nourishes the photoreceptors and is vital in maintaining healthy eyesight.

In fact, the dysfunction and death of RPE is thought to be behind the leading cause of blindness in the Western world — age related macular degeneration.

Transplantation of RPE cells into the retina to treat AMD has been demonstrated in animals and is now being tested in clinical trials in humans. However, protocols to generate RPE from human pluripotent stem cells are time consuming and relatively inefficient. But a team of scientists at the University of California, Santa Barbara, reports in the latest issue of STEM CELLS Translational Medicine that it has found a way to isolate RPE cells as early as 14 days following the onset of differentiation.

"RPE cells are required for visual function and are a reasonable candidate for use in cellular therapy to treat macular degeneration. This study shows that it is now possible to produce homogeneous cultures in a shorter period of time," said James Thomson, a Wisconsin-based researcher who was the first to isolate human embryonic stem cells, commenting on the study.

The UCSB research team was led by Dennis Clegg, Ph.D., Peter Coffey, Ph.D., and David Buchholz, Ph.D. They based their study on earlier reports that neural retinal progenitors could be generated through the application of a handful of regulatory proteins, known as factors, that stimulate cell growth and function.

“As RPE and the neural retina arise from a common progenitor pool, we sought to determine whether this protocol could be altered to di
'/>"/>

Source: PRWeb
Copyright©2012 Vocus, Inc.
All rights reserved

Page: 1 2 3

Related biology technology :

1. A bright idea: Tiny injectable LEDs help neuroscientists study the brain
2. Highly lethal Ebola virus has diagnostic Achilles heel for biothreat detection, scientists say
3. NineSigma Announces Winners in $25,000 Sustainable Packaging Challenge in Conjunction With Scientists Without Borders and Partners
4. Research Team led by JCVI Scientists Uncover More Complexity and Detail in Southern African Genomic Diversity
5. Dr. Ali S. Faqi and Leading Scientists Author Ground-Breaking Toxicology Book from Elsevier
6. Scientists discover molecule that does double duty in stopping asthma attacks
7. Scientists Warn of Long Term Consequences of Budget Sequestration: BioInformatics LLC Report
8. UC Santa Barbara scientists develop a whole new way of harvesting energy from the sun
9. The Elsevier Foundation, TWAS, and OWSD Honor Early Career Women Scientists in Developing Countries at the Annual AAAS Meeting
10. BioInformatics LLC New Market Report – Best Practices Guide for Advertising to Life Scientists
11. Science of Hiring: Demand for Scientists Grows 15%
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:1/22/2015)... Jan. 22, 2015   Cypher Genomics, Inc., ... (NASDAQ: SQNM ), the leading molecular ... next generation noninvasive prenatal tests (NIPT). Through this ... called Mantis™, to advance analysis of clinically-relevant fetal ...
(Date:12/25/2014)... report “Service Quality Management and Telco Customer Experience Management ... Advancements, Worldwide Forecasts & Analysis (2014-2019)” defines and segments ... revenues. , Browse 152 market data tables, 19 ... “Service Quality Management (SQM) and Telco Customer Experience Management ...
(Date:12/24/2014)... Dec. 24, 2014   BioLife Solutions , Inc. (NASDAQ: ... proprietary clinical grade hypothermic storage and cryopreservation ... for cells and tissues  ("BioLife" or the "Company"), today announced ... on May 4, 2015 (the "Annual Meeting"). Because ...
(Date:12/24/2014)... MA (PRWEB) December 23, 2014 ... is designed to introduce cutting edge communication technology, ... of platform upgrades. This webinar series demonstrates online ... quest to leverage web conferencing’s most innovative and ...
Breaking Biology Technology:Cypher Genomics and Sequenom Announce Development Agreement 2Cypher Genomics and Sequenom Announce Development Agreement 3Cypher Genomics and Sequenom Announce Development Agreement 4Service Quality Management Market worth $2.1 Billion & Telco Customer Experience Management Market worth $2.3 Billion by 2019 – New Report by MarketsandMarkets 2Service Quality Management Market worth $2.1 Billion & Telco Customer Experience Management Market worth $2.3 Billion by 2019 – New Report by MarketsandMarkets 3Service Quality Management Market worth $2.1 Billion & Telco Customer Experience Management Market worth $2.3 Billion by 2019 – New Report by MarketsandMarkets 4BioLife Solutions Sets Date for Annual Meeting of Stockholders 2SoundConnect Launches Leading Edge Business Communications Webinar Series 2SoundConnect Launches Leading Edge Business Communications Webinar Series 3
... Vasogen Inc. (NASDAQ: VSGN ; TSX:VAS) today announced ... and its related foreign counterparts for US$400,000. This device-based ... the Celacade System; however, Vasogen has retained rights to ... to its Celacade System. , The Company today also ...
... benefits of silicone technology for healthcare applications, Polymer ... Polymer Science, Inc. will introduce a new ... (booth 1646) from February 10-12 in Anaheim, California. ... market for innovative skin contact applications, Polymer Science ...
... Feb. 2 More than a dozen internationally renowned ... transition team, will be coming to New Haven, CT ... research symposium taking place March 23-24, 2009.The roster includes ... announced creation of two new human embryonic stem cell ...
Cached Biology Technology:Vasogen Announces Sale of Patent Application and Provides Corporate Update 2Polymer Science Releases New Silicone Gel Adhesive Products for MD&M West 2Obama Advisor Joins Connecticut and International Scientists at New Haven Stem Cell Symposium 2
(Date:12/22/2014)... , Dec. 22, 2014  The 2014 Holiday Season ... as Acuity Market Intelligence reports that the long anticipated ... forecasts that intensifying demand for smart phones, tablets, and ... global market of 2.5 billion users with nearly 4.8 ...
(Date:12/17/2014)... , Dec. 15, 2014 Research and Markets ... "Samsung Galaxy S5 - Home Button Synaptics Fingerprint ... http://photos.prnewswire.com/prnh/20130307/600769 Based ... 5S, Samsung introduces for the first time a fingerprint ...
(Date:12/17/2014)... 16, 2014  Automation is fundamentally transforming the travel experience ... borders. Over the past decade, ePassports, biometric readers, and ... process through border control via eGates and Automated Passport ... seaports, and land borders across the globe. ...
Breaking Biology News(10 mins):First Season of Holiday Shopping with Mobile Biometric Payments Wraps Up With a Present for Biometrics Industry: A Rosy Forecast for More Than 2 Billion Users of 4.8 Billion Mobile Biometric Devices by 2020 2Samsung Galaxy S5 - Home Button Synaptics Fingerprint Sensor Technology Analysis 2Automated Border Control (ABC) Transforms the Global Travel Experience With More Than 2500 ABC eGates and APC Kiosks Deployed In Airports, Seaports, and Land Borders Worldwide 2
... we can break you." If Rice University scientists wrote country ... that. But this song wouldn,t break anybody,s heart. A ... demonstrates an environmentally friendly way to make bulk quantities of ... to find use in all kinds of material and electronic ...
... An after-school snack of graham crackers might be one way ... study from the University of Minnesota shows. Federal nutrition ... foods, but previous studies have found that children typically only ... like the taste or texture of whole-grain foods. In ...
... A Michigan State University researcher is working to ... nerve cells fight off damage from Parkinson,s disease, a ... degenerative ailment. John Goudreau, an osteopathic physician and ... can rescue certain neurons from injury induced by Parkinson,s ...
Cached Biology News:Graphene oxide gets green 2Graphene oxide gets green 3Specific protein may help neurons fix themselves in Parkinson's patients 2
Detects activated caspases in living cells. Simple/sensitive/straight-forward procedure takes only 30 minutes. Results can be analyzed by flow cytometry/fluorescence microscopy/fluorescence plate rea...
Apoptosis Detection Systems and Reagents...
Bovine Serum Available Anticoagulants: N-02: Citrate N-04: Heparin (Na) N-06: K2EDTA N-08: Potassium Oxalate N-10: EDTA (Na) N-03: Alsevers N-05: ACD N-07: CPD N-09: K3EDTA N-11:...
...
Biology Products: