Navigation Links
SRI International Scientists Discover Brain Circuit Activated during Sleep
Date:12/10/2013

MENLO PARK, Calif., Dec. 10, 2013 /PRNewswire/ -- Neuroscientists at SRI International have discovered a brain circuit that appears to be related to the restorative function of sleep. The findings point to a biochemical and physiological explanation of how sleep need, which gradually builds up during wakefulness, is dissipated during sleep.

"We all know sleep is important for restoration in some way, but scientists have yet to define what actually needs to be restored or how the restoration occurs," said the study leader, Thomas Kilduff, Ph.D., who directs the Center for Neuroscience within SRI Biosciences. "We have found a group of cells in the cerebral cortex that appear to orchestrate the slow waves that occur during sleep, which have been linked to sleep restoration."

The research, published in the December 10 issue of Proceedings of the National Academy of Sciences (PNAS), identifies specific brain cells that are activated during the deep stages of sleep known as slow wave sleep, and identifies the chemical responsible as nitric oxide. The long-term implications of these findings include nitric oxide as a potential target for medications that help facilitate slow wave sleep in conditions where it is diminished, such as aging.

Sleep researchers have long sought to understand why we become sleepy and how sleep restores mental and physical performance. "One clue to sleepiness is that the recovery process during sleep seems to be related to brain slow wave activity, which is high when we first fall asleep and declines through the night," said Kilduff. "When we stay awake for a longer period of time, once we fall asleep, the slow waves are larger in size and more intense."

Sleep stages are identified by electroencephalography
'/>"/>

SOURCE SRI International
Copyright©2012 PR Newswire.
All rights reserved

Page: 1 2 3 4

Related biology technology :

1. Dr. Renu Razdan of Max Neeman International Appointed Vice Chairman, ACRO India
2. 2014 International Conference on Cancer Nursing (ICCN) in Panama City, Panama - Call for Abstracts
3. NSF International Acquires Brazil’s Bioensaios Analysis and Environmental Consultancy Ltd., a Leading Analytical Laboratory
4. ISPE Announces Recipients of 2013 International Honor Awards at Global Annual Meeting
5. Dyadic International To Present At Two Major Conferences In December 2013
6. Marrone Bio Innovations Establishes International Science Advisory Panel
7. Annai Systems to Support International Challenge to Improve the Detection of Cancer Mutations
8. International Collaboration Puts the Future of Healthcare IT on Display at the University City Science Center
9. Edison expands international biotechnology presence with launch of full coverage of Athersys
10. Dyadic International Reports Third Quarter 2013 Financial Results
11. Vet-Stem, Inc. Proudly Announces Distribution Agreement with Animal Health International, Inc. for Regenerative Cell Therapies
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:5/21/2015)... May 21, 2015  Susan Hedstrom, Executive Director ... nonprofit organization dedicated to supporting research to advance ... announced today that FPWR has received the organization,s ... Shaulov contributed $1 million in support of ... "Our gift signifies ...
(Date:5/21/2015)... May 21, 2015 W. R. ... manufacturing facility in Worms, Germany has received good ... subsidiary of the International Pharmaceutical Excipient Council (IPEC) ... that produce its SYLOID® FP brand of pharmaceutical ... certification, following the Curtis Bay, Maryland (USA) and ...
(Date:5/21/2015)... 2015 /PRNewswire/ - RepliCel Life Sciences Inc. (TSX.V: ... company focused on the development of autologous cell ... the International Society for Cellular Therapy (ISCT) on ... currently in a Phase 1/2 clinical trial.  The ... from 5:30 PM to 7:00 PM local time, ...
(Date:5/20/2015)... MA (PRWEB) May 20, 2015 This ... history, especially for lawns. US Patented Pearl’s Premium ... for lawns around the country that are coming out ... that addresses a number of major global concerns related ... the “non-grass” grass – the alternative to the standard, ...
Breaking Biology Technology:The Foundation for Prader-Willi Research Receives $1M Contribution in Support of Clinical Initiatives 2Grace European Facility Receives GMP Excipient Certification for SYLOID® FP Silica Gel 2RepliCel to Present Unique Autologous Cell Treatment for Achilles Tendinosis at International Society for Cellular Therapy Conference 2RepliCel to Present Unique Autologous Cell Treatment for Achilles Tendinosis at International Society for Cellular Therapy Conference 3Breakthrough 4th Generation Low Maintenance Lawn Seed Offers Solution to California Drought 2
... familiar with these three words, after all that has happened ... shown the importance of being current with ones network security ... attacks came via the blaster worm, which took advantage of ... Following closely on its heels were Sobig, Nacha, and ...
... bread and butter of Wisconsins economic growth will be ... to transfer our best technology to the marketplace, controlling ... ensuring theres a 21st century infrastructure in place to ... to the equation, too, that may prove as vital ...
... WI- Frost & Sullivan has announced that Camtronics ... Corporation as the recipient of both the 2003 ... information management market and the 2003 Market Penetration Leadership ... , ,Outstanding achievements in these areas have helped ...
Cached Biology Technology:Athletics, pop culture and the arts 2Athletics, pop culture and the arts 3Camtronics Receives Health IT Awards 2
(Date:5/14/2015)... YORK , May 14, 2015 /PRNewswire/ ... in identity verification and online remote proctoring, ... a software-as-a-service (SaaS) company and creator of ... customers of the two companies will benefit ... in Canvas. As a fully ...
(Date:5/11/2015)... 11, 2015 Curemark LLC, a privately held ... a new Phase III double blind, randomized, placebo-controlled clinical ... CM-AT, on all children ages 3-8 with Autism. Previously, ... III double blinded clinical trial for CM-AT in children ... the digestive enzyme chymotrypsin. This new trial will help ...
(Date:5/7/2015)... Sweden , May 7, 2015 ... touch fingerprint sensors, FPC1022 and FPC1035, FPC,s smallest ... and FPC1035 are mainly considered for integration on ... size gives smartphone OEMs increased possibilities to integrate ... The decreased size also improves possibilities for module ...
Breaking Biology News(10 mins):Verificient and Instructure Announce Alliance Partnership to Provide Online Proctoring for K-12 and Higher Education Institutions 2Curemark, LLC, Launches New Phase III Trial in Expanded Population of Children with Autism 2FPC Introduces its Smallest Touch Fingerprint Sensors to Date 2
... making the public aware of the stark difference between ... from Professor Barry Brook, Director of the Research Institute ... Adelaide, Australia. In an opinion piece published today ... has urged scientists to stand up to those who ...
... press release is not and,must not be, directly or ... Africa or the United States of America. The,Offer is ... elsewhere,where their participation requires further offer documents, filings or,other ... This is a,translation of the original Swedish language press ...
... a leading supplier of broadband technology and biometrics software,has ... results,for the first quarter of 2008 on Thursday, May ... and CFO Rick Moberg will host the,earnings conference call., ... can be accessed on the,Investor Relations page of our ...
Cached Biology News:Scientists urged to make a stand on climate change 2Oberthur Technologies XPon Offer 2Aware Announces Q1 2008 Earnings Conference Call 2
... delivers enhanced statistics and statistical interpretation ... improvement managers. As an accepted organizational ... simplifies statistics for novice users and ... experts. It offers a powerful JMP ...
... Choice Microsphere/Microarray Stabilizer is a is a ... This product is an aqueous solution ... buffer (phosphate buffered saline), pH 6.6 - ... of 0.02% methylisothiazolone and 0.02% bromonitrodioxane as ...
... Microarray plates are ideal for use as source ... handling applications (down to 5µl). These plates are ... design. Features 384 round ... 70µl well volume (cylindrical well), 55µl well ...
... is an aqueous-based mounting medium designed ... sections. Gel/Mount is especially recommended when ... or FluoroBlue. It can also be ... as fluorescein (FITC), Rhodamine (TMRITC) and ...
Biology Products: