Navigation Links
Researchers strike gold with nanotech vaccine
Date:6/26/2013

Scientists in the US have developed a novel vaccination method that uses tiny gold particles to mimic a virus and carry specific proteins to the body's specialist immune cells.

The technique differs from the traditional approach of using dead or inactive viruses as a vaccine and was demonstrated in the lab using a specific protein that sits on the surface of the respiratory syncytial virus (RSV).

The results have been published today, 26 June, in IOP Publishing's journal Nanotechnology by a team of researchers from Vanderbilt University.

RSV is the leading viral cause of lower respiration tract infections, causing several hundred thousand deaths and an estimated 65 million infections a year, mainly in children and the elderly.

The detrimental effects of RSV come, in part, from a specific protein, called the F protein, which coats the surface of the virus. The protein enables the virus to enter into the cytoplasm of cells and also causes cells to stick together, making the virus harder to eliminate.

The body's natural defence to RSV is therefore directed at the F protein; however, up until now, researchers have had difficulty creating a vaccine that delivers the F protein to the specialised immune cells in the body. If successful, the F protein could trigger an immune response which the body could 'remember' if a subject became infected with the real virus.

In this study the researchers created exceptionally small gold nanorods, just 21 nanometres wide and 57 nanometres long, which were almost exactly the same shape and size as the virus itself. The gold nanorods were successfully coated with the RSV F proteins and were bonded strongly thanks to the unique physical and chemical properties of the nanorods themselves.

The researchers then tested the ability of the gold nanorods to deliver the F protein to specific immune cells, known as dendritic cells, which were taken from adult blood sample
'/>"/>

Contact: Michael Bishop
michael.bishop@iop.org
01-179-301-032
Institute of Physics
Source:Eurekalert

Page: 1 2

Related biology technology :

1. New England Biolabs Introduces Polbase, an Information Repository of Scientific Data for Polymerase Researchers
2. In new quantum-dot LED design, researchers turn troublesome molecules to their advantage
3. Multidisciplinary team of researchers develop world’s lightest material
4. Researchers shrink tumors and minimize side effects using tumor-homing peptide to deliver treatment
5. Innovative MetaMorph® NX Software Shatters Barriers Between Researchers and Image Analysis Goals with Exclusive Visual Workflow
6. UCLA researchers demonstrate fully printed carbon nanotube transistor circuits for displays
7. Penn and Brown researchers demonstrate earthquake friction effect at the nanoscale
8. Two Top Biological Imaging Centers Offer Powerful Free Online Tool to Researchers, Educators, and Public
9. Researchers develop one of the worlds smallest electronic circuits
10. MU researchers identify key plant immune response in fight against bacteria
11. Researchers realize high-power, narrowband terahertz source at room temperature
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:10/22/2014)... -- Research and Markets has announced ... Market (Product types, Application, Technology, End User and ... Demand, Insights, Analysis, Research, Report, Opportunities, Segmentation and ... offering. This new report titled, ... and Geography) Global Size, Industry Analysis, Trends, Opportunities, ...
(Date:10/22/2014)... Involution Studios , a healthcare software ... infographic, Understanding Ebola . The goal of ... to follow informative tool for anyone wanting to know ... prevention. , "As the news has spread in all ... represents not only a healthcare crisis with global impact, ...
(Date:10/22/2014)... 2014 According to new market ... Type (Consulting, Integration, Deployment & Support), by Service ... (Public, Private, Others (Hybrid & Community)) - Global ... segments the Cloud Professional Services Market into various ... revenues. It also identifies the drivers and restraints ...
(Date:10/22/2014)... DIEGO and HONG KONG ... innovative rare disease therapeutics enterprise, announced today that rare ... the company as vice president, research. Dr. McKew brings ... including key leadership positions at the National Institutes of ... its acquisition by Wyeth). Dr. McKew will lead aTyr,s efforts ...
Breaking Biology Technology:Global DNA Diagnostics Market (Product types, Application, Technology, End User and Geography) - Forecast to 2020 2Global DNA Diagnostics Market (Product types, Application, Technology, End User and Geography) - Forecast to 2020 3Involution Studios' Ebola Infographic Provides Key Disease Information and Statistics at a Glance 2Cloud Professional Services Market by Public, Private, Hybrid & Community Expected to Reach $34.41 Billion by 2019 - New Report by MarketsandMarkets 2Cloud Professional Services Market by Public, Private, Hybrid & Community Expected to Reach $34.41 Billion by 2019 - New Report by MarketsandMarkets 3Cloud Professional Services Market by Public, Private, Hybrid & Community Expected to Reach $34.41 Billion by 2019 - New Report by MarketsandMarkets 4Cloud Professional Services Market by Public, Private, Hybrid & Community Expected to Reach $34.41 Billion by 2019 - New Report by MarketsandMarkets 5aTyr Pharma Appoints John C. McKew, Ph.D., as Vice President, Research 2aTyr Pharma Appoints John C. McKew, Ph.D., as Vice President, Research 3
... 15, 2011 Delcath Systems, Inc. (NASDAQ: ... symposium at the Interventional Radiology and Endovascular Surgery Society ... PHP – A New Evidenced-Based Technology for the Treatment ... 2011, and featured a presentation by Delcath,s Executive Vice ...
... it is now imperative to redefine what makes a successful ... waste management is not thought out from the beginning, the ... energy choice, according to research that appears today in the ... According to Allison Macfarlane, associate professor of environmental science ...
... Institute of Molecular and Cell Biology (IMCB) has discovered ... deadly plant toxin Ricin, widely feared for its bioterrorism ... for the tens of thousands of hospital-acquired infections in ... this first ever genome-wide study to understand how the ...
Cached Biology Technology:Delcath Systems, Inc. Hosts Symposium on Chemosaturation at the SOBRICE Annual Meeting in Brazil 2Delcath Systems, Inc. Hosts Symposium on Chemosaturation at the SOBRICE Annual Meeting in Brazil 3Nuclear waste requires cradle-to-grave strategy 2Nuclear waste requires cradle-to-grave strategy 3A*Star scientists discover how to combat hospital-acquired infections and life-threatening toxins 2A*Star scientists discover how to combat hospital-acquired infections and life-threatening toxins 3
(Date:10/15/2014)... is a non-traditional biophysics textbook and it describes how ... journey of discovery into biological systems and provides an ... It is about how our genes make proteins that ... of cells in an organism. It quantifies the principles ... can be found on both large and small scales. ...
(Date:10/15/2014)... 15, 2014 NXT-ID, Inc. (NASDAQ: NXTD ... on the growing mobile commerce market releases photos and video of ... on Monday October 13 th . Gino ... and angel investor Mr. Chad A. Verdi rang ... NXT-ID thanked his investors and employees "for their work and dedication ...
(Date:10/14/2014)... Cancer Research shows SIRT6—a protein known to ... the development of skin cancers by turning on an ... skin cells. , Previously considered protective, SIRT6 is part ... help regulate genomic stability and prevent some of the ... damage, which can lead to cancer. This study, in ...
Breaking Biology News(10 mins):New book about life as seen from physics 2Photo Release: NXT-ID Inc. Rings Opening Bell of the NASDAQ Stock Market October 13th 2Photo Release: NXT-ID Inc. Rings Opening Bell of the NASDAQ Stock Market October 13th 3Two-faced gene: SIRT6 prevents some cancers but promotes sun-induced skin cancer 2
... New Haven, Conn.Paleontologists have discovered the oldest mammalian tooth ... several large dinosaurs. They report their findings in a ... Paleontology . Nicholas Longrich of Yale University ... Natural History came across several of the bones while ...
... COLLEGE STATION, June 14, 2010 - Haze, scientifically known ... Earth,s atmosphere - represents a major environmental problem because ... climate. Despite its profound impacts, how the haze is ... University professor of atmospheric sciences and chemistry who has ...
... Just as President Barack Obama called for in his ... BP and all other companies be responsible to both their ... University,s Jones Graduate School of Business. The rigorous ... spill in the Gulf of Mexico found that Republicans, Democrats ...
Cached Biology News:Dinosaur-chewing mammals leave behind oldest known tooth marks 2Research is getting closer to understanding critical nucleus in haze formation, prof says 2Consumer responses to Gulf oil spill reflect Americans' changing corporate expectations 2