Navigation Links
Researchers identify signals that direct the immune system to reject a transplanted organ
Date:5/17/2013

Organ transplant rejection occurs when the transplant recipient's immune system identifies the transplanted organ as foreign tissue and attacks it. It was previously thought that T cells, the immune cells that mediate rejection, must first be activated by molecules known as chemokines in order to migrate to the transplanted organ. In this issue of the Journal of Clinical Investigation, Fadi Lakkis and colleagues at the University of Pittsburgh used mice to demonstrate that chemokine stimulation of T cells is not required for migration. Instead, these cells must come into contact with immune-stimulating proteins (antigens) that are specifically expressed by the transplanted organ. In an accompanying commentary, Terry Strom discusses how these findings could have important implications for the design of novel anti-rejection therapeutics.


'/>"/>

Contact: Jillian Hurst
press_releases@the-jci.org
Journal of Clinical Investigation
Source:Eurekalert

Page: 1

Related biology technology :

1. Top Genetic and Cellular Researchers Honored at ASGCT 16th Annual Meeting
2. Pioneering Researchers Recognized for Scientific Achievements in Gene and Cell Therapy
3. SPIE Smart Structures/NDE Researchers Look to Nature for Inspiration
4. South Dakota School of Mines & Technology Researchers Document Splitting Water Molecules in Multiple Thermochemical Cycles with Goal to Sustain Hydrogen Energy
5. Israel’s Top BioEnergy Researchers Are Arriving Today at Oak Ridge National Laboratory For Deliberations to Establish U.S.-Israel Collaboration
6. Researchers untangle molecular pathology of giant axonal neuropathy
7. Top BioEnergy Researchers and Innovators Arriving Next Week to Foster U.S.-Israel Collaboration
8. Researchers identify transcription factors that regulate retinal vascularization
9. Bean leaves can trap bedbugs, researchers find
10. Elsevier and the Belarus Ministry of Education Honor Researchers with Scopus Awards
11. Beekeepers, Researchers and Bayer CropScience Associate Overwintering Bee Losses with Varroa Mite
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:1/15/2014)... 2013 was a banner year of continued innovation ... continued independent research led by the team at Wake ... million grant from the Susanne Marcus Collins Foundation, had ... reviewed journal, Amy Grant highlighted Brainwave Optimization® in First ...
(Date:1/14/2014)... DC (PRWEB) January 14, 2014 Carahsoft ... for Thursday, January 23, 2014 at 2pm EST (11am ... Knowledge.” The topic focuses on how technology can turn ... critical decisions for government agencies. The online webinar will ...
(Date:1/14/2014)... , Jan. 14, 2014 The largest international ... medicinal plants and therapeutic derivatives thereof has endorsed ... and researchers about the challenges of adulterated herb ... ) The Society for Medicinal ...
(Date:1/14/2014)... 14, 2014 Global Record Systems, ... information technology solutions for patients, physicians, the biopharmaceutical ... announced today the signing of a three-year Research ... Drug Administration (FDA). This initiative is designed ...
Breaking Biology Technology:Dynamic Innovative Technology Showcased at Scottsdale Company’s Open House 2Dynamic Innovative Technology Showcased at Scottsdale Company’s Open House 3Webcast - Natural Language Processing: Converting Raw Data into Actionable Knowledge – Hosted by Carahsoft and CDS Federal Services 2World's Largest Group of Medicinal Plant Researchers Endorses ABC-AHP-NCNPR Botanical Adulterants Program 2World's Largest Group of Medicinal Plant Researchers Endorses ABC-AHP-NCNPR Botanical Adulterants Program 3World's Largest Group of Medicinal Plant Researchers Endorses ABC-AHP-NCNPR Botanical Adulterants Program 4World's Largest Group of Medicinal Plant Researchers Endorses ABC-AHP-NCNPR Botanical Adulterants Program 5World's Largest Group of Medicinal Plant Researchers Endorses ABC-AHP-NCNPR Botanical Adulterants Program 6World's Largest Group of Medicinal Plant Researchers Endorses ABC-AHP-NCNPR Botanical Adulterants Program 7World's Largest Group of Medicinal Plant Researchers Endorses ABC-AHP-NCNPR Botanical Adulterants Program 8Global Record Systems Announces Research Collaboration Agreement with FDA to Create a Novel “Big Data” Paradigm for Collection of Patient Safety and Outcomes Information 2
... exciting new and unique products; ... in near future ..., BOCA RATON, Fla., May 2 ... stock is now,up and trading on the Pink Sheets. The stock ... From this point,Solei will continue on toward becoming a fully reporting ...
... 2 /PRNewswire-FirstCall/ - GeneNews Limited (TSX: GEN), ... for the early,detection of diseases and personalized ... for the first quarter ended March 31,2008., ... of the key milestones,necessary to support the ...
... IRVINE, Calif., May 1 Masimo Corporation,(Nasdaq: MASI ... that it is scheduled to present at the Deutsche ... in Boston, MA,on Tuesday, May 6, 2008 at 9:30 ... A live Web cast of the presentation will be ...
Cached Biology Technology:Solei Systems, Inc., Announces That the Company Is Now Publicly Traded 2Solei Systems, Inc., Announces That the Company Is Now Publicly Traded 3Solei Systems, Inc., Announces That the Company Is Now Publicly Traded 4GeneNews Announces First Quarter Results 2GeneNews Announces First Quarter Results 3GeneNews Announces First Quarter Results 4GeneNews Announces First Quarter Results 5GeneNews Announces First Quarter Results 6GeneNews Announces First Quarter Results 7GeneNews Announces First Quarter Results 8Masimo to Present at Deutsche Bank 33rd Annual Health Care Conference 2
(Date:4/17/2014)... German . ... demanded of him, he can expect his premises to be ... of the consequences is enough to make restaurant owners pay ... lay their eggs in other birds, nests. If the host ... their revenge by destroying the entire nest. Consequently, it is ...
(Date:4/17/2014)... in many serious conditions such as heart disease, epilepsy ... drug therapies. Unfortunately, there is still much scientists do ... fresh and unexpected insight into the structure of sodium ... molecules - which are responsible for ,fine-tuning, the activity ... most recent edition of the Journal of Biological ...
(Date:4/17/2014)... genetic information of DNA is used to manufacture ... different functions in living organisms. Messenger RNA (mRNA) ... by relating the genetic information of DNA to ... , By examining the different types and amounts ... a given time, researchers can determine which specific ...
Breaking Biology News(10 mins):Fear of the cuckoo mafia 2Fear of the cuckoo mafia 3Structure of sodium channels different than previously believed 2Rapid and accurate mRNA detection in plant tissues 2
... position paper by researchers at the European Centre for ... Peninsula College of Medicine and Dentistry) and the University of ... virtual natural environments and concluded that the development of accurate ... interact with nature because of infirmity or other limitations: ...
... 2011 A new study from University of Miami ... Chris Langdon, Remy Okazaki and Nancy Muehllehner and colleagues ... Max-Planck Institute for Marine Microbiology in Germany concludes that ... severely reduce the diversity and resilience of coral reef ...
... researcher Elias Tomaras says the idea came to him while ... "If you watch sprinters, short distance speed skaters or cyclists ... two hours, including several brief bouts of high intensity exercise. ... it might be pretty tiring." Many coaches and physiologists ...
Cached Biology News:Virtual natural environments and benefits to health 2Virtual natural environments and benefits to health 3Virtual natural environments and benefits to health 4Tiny bubbles signal severe impacts to coral reefs worldwide 2When it comes to warm-up, less is more 2
Caliper offers a wide array of standard LabChip products designed to be used in combination with our AMS 90 and LabChip 3000 microfluidic platforms....
Experion StdSens chips are the microfluidic chips used to perform standard-sensitivity RNA analysis (nanogram levels) with the Experion automated electrophoresis system. Each chip has the capacity to...
...
Experion HighSens chips are the microfluidic chips used to perform high-sensitivity RNA analysis (picogram levels) with the Experion automated electrophoresis system. Each chip has the capacity to ru...
Biology Products: