Navigation Links
Researchers identify signals that direct the immune system to reject a transplanted organ
Date:5/17/2013

Organ transplant rejection occurs when the transplant recipient's immune system identifies the transplanted organ as foreign tissue and attacks it. It was previously thought that T cells, the immune cells that mediate rejection, must first be activated by molecules known as chemokines in order to migrate to the transplanted organ. In this issue of the Journal of Clinical Investigation, Fadi Lakkis and colleagues at the University of Pittsburgh used mice to demonstrate that chemokine stimulation of T cells is not required for migration. Instead, these cells must come into contact with immune-stimulating proteins (antigens) that are specifically expressed by the transplanted organ. In an accompanying commentary, Terry Strom discusses how these findings could have important implications for the design of novel anti-rejection therapeutics.


'/>"/>

Contact: Jillian Hurst
press_releases@the-jci.org
Journal of Clinical Investigation
Source:Eurekalert

Page: 1

Related biology technology :

1. Top Genetic and Cellular Researchers Honored at ASGCT 16th Annual Meeting
2. Pioneering Researchers Recognized for Scientific Achievements in Gene and Cell Therapy
3. SPIE Smart Structures/NDE Researchers Look to Nature for Inspiration
4. South Dakota School of Mines & Technology Researchers Document Splitting Water Molecules in Multiple Thermochemical Cycles with Goal to Sustain Hydrogen Energy
5. Israel’s Top BioEnergy Researchers Are Arriving Today at Oak Ridge National Laboratory For Deliberations to Establish U.S.-Israel Collaboration
6. Researchers untangle molecular pathology of giant axonal neuropathy
7. Top BioEnergy Researchers and Innovators Arriving Next Week to Foster U.S.-Israel Collaboration
8. Researchers identify transcription factors that regulate retinal vascularization
9. Bean leaves can trap bedbugs, researchers find
10. Elsevier and the Belarus Ministry of Education Honor Researchers with Scopus Awards
11. Beekeepers, Researchers and Bayer CropScience Associate Overwintering Bee Losses with Varroa Mite
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:12/9/2016)... /PRNewswire/ - Portage Biotech Inc. ("Portage" or "the Company") ... announce that Biohaven has issued today the following press ... (PRWEB) Dec 9, 2016 - Biohaven Pharmaceutical Holding ... the U.S. Food and Drug Administration ("FDA") has granted ... candidate BHV-0223, an orally dissolving tablet being developed for ...
(Date:12/8/2016)... CA (PRWEB) , ... December 08, 2016 , ... Lajollacooks4u, ... was a banner year for team building events, new program offerings and company expansion. ... it expanded earlier this year to include groups of over 30 people. Ever since, ...
(Date:12/8/2016)...  Biotheranostics today announced that new data will ... Cancer Index (BCI) in identifying which patients with ... for disease recurrence and might benefit from extended ... advancing the understanding of the value of BCI ... inform decisions related to patient treatment. These data ...
(Date:12/8/2016)... ... December 08, 2016 , ... Opal Kelly, ... essential device-to-computer interconnect using USB or PCI Express, announced the FOMD-ACV-A4, the company's ... is a small, thin, SODIMM-style module that fits a standard 204-pin SODIMM socket ...
Breaking Biology Technology:
(Date:11/29/2016)... , November 29, 2016 Nearly one billion ... Continue Reading ... ... part of an efficient Identity Management. (PRNewsFoto/DERMALOG Identification Systems) ... DERMALOG is Germany's largest Multi-Biometric supplier: The ...
(Date:11/21/2016)... Lithuania , Nov. 21, 2016   ... and object recognition technologies, today announced that the ... smart cards was submitted for the NIST ... successfully passed all the mandatory steps of the ... evaluation is a continuing test of fingerprint templates ...
(Date:11/15/2016)... Nov. 15, 2016  Synthetic Biologics, Inc. (NYSE ... focused on the gut microbiome, today announced the ... shares of its common stock and warrants to ... a price to the public of $1.00 per ... Biologics from the offering, excluding the proceeds, if ...
Breaking Biology News(10 mins):