Navigation Links
Researchers create the world's most advanced genetic map
Date:7/20/2011

ly in people of African ancestry.

These findings are expected to help researchers understand the roots of congenital conditions that occur more often in African Americans (due to mutations at hotspots that are more common in African Americans), and also to help discover new disease genes in all populations, because of the ability to map these genes more precisely.

The new map is so accurate because African American individuals often have a mixture of African and European ancestry from over the last two hundred years. David Reich and Simon Myers are experts in analyzing genetic data to reconstruct the mosaic of regions of African and European genetic ancestry in DNA of African Americans. By applying a computer program they previously wrote, Anjali Hinch identified the places in the genomes where the African and European ancestry switches in almost 30,000 people, detecting about 70 switches per person. These areas corresponded to recombination events in the last few hundred years. Thus, the researchers identified more than two million recombination events that they used to build the map.

The study was only possible because of collaboration from 81 co-authors, using DNA samples from five large studies that have been carried out to study common diseases such as heart disease and cancer, funded by the National Institutes of Health, the Department of Defense, and many private foundations.

Said James Wilson, a professor at the University of Mississippi Medical Center who was responsible for coordinating the collaboration, "All the co-authors worked together in an incredibly collegial way to put together the enormous set of samples and high quality genetic data that made this study a success."


'/>"/>

Contact: David Cameron
david_cameron@hms.harvard.edu
617-432-0442
Harvard Medical School
Source:Eurekalert

Page: 1 2 3

Related biology technology :

1. Penn researchers show single drug and soft environment can increase platelet production
2. SANYO and BD Biosciences Collaborate to Offer Researchers Valuable Technology and Research Tools
3. TUM researchers develop environmentally friendly process to improve storage stability of probiotics
4. Researchers image graphene electron clouds, revealing how folds can harm conductivity
5. Researchers clarify properties of confined water within single-walled carbon nanotube pores
6. Researchers engineer the environment for stem cell development to control differentiation
7. Penn researchers break light-matter coupling strength limit in nanoscale semiconductors
8. Researchers From More Than 30 Countries Share Findings About the Use of Ultrasound in the Prevention, Diagnosis and Treatment of Heart Disease
9. Singapore researchers invent broadband graphene polarizer
10. Livermore researchers develop battery-less chemical detector
11. Researchers create terahertz invisibility cloak
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:10/20/2014)... OR (PRWEB) October 20, 2014 Local ... participate in an investigational study of donor stem cells ... in stem cell therapy and has performed clinical stem ... this study is to determine if a single injection ... affected joints can help reduce pain and inflammation in ...
(Date:10/19/2014)... 2014 NextCODE Health, which enables clinicians and researchers ... time, today announced the launch of its new genomic data ... the American Society of Human Genetics (ASHG) annual meeting in ... up and apply for free beta access, visit www.nextcode.com ... can be viewed here . The Exchange: ...
(Date:10/19/2014)... 19, 2014 The Asia-Pacific Speech Analytics ... in Asia-Pacific with analysis and forecast of revenue. This ... 2014 to $208 million by 2019, at a Compound ... 2019. , Browse through the TOC of the Asia-Pacific ... the in-depth analysis provided. It also provides a glimpse ...
(Date:10/19/2014)... The report "Unmanned Ground Vehicle ... Technology, Payload, Type & by Geography - Forecasts ... unmanned ground vehicle market into various sub segments ... sizes. The report also identifies the factors driving ... along with the adoption trends. , The unmanned ...
Breaking Biology Technology:Cascade Veterinary Referral Center Seeks Candidates for an Investigational Study of Stem Cells for Dogs with Arthritis 2The NextCODE Exchange: The first global, real-time system for sharing full-resolution genomic data 2The NextCODE Exchange: The first global, real-time system for sharing full-resolution genomic data 3The Asia-Pacific Speech Analytics market is estimated to reach $208 million by 2019 - New Report by MicroMarket Monitor 2The Asia-Pacific Speech Analytics market is estimated to reach $208 million by 2019 - New Report by MicroMarket Monitor 3The Asia-Pacific Speech Analytics market is estimated to reach $208 million by 2019 - New Report by MicroMarket Monitor 4Unmanned Ground Vehicle (UGV) Market Estimated to Reach $8.26 Billion by 2020 - New Research Report by MarketsandMarkets 2Unmanned Ground Vehicle (UGV) Market Estimated to Reach $8.26 Billion by 2020 - New Research Report by MarketsandMarkets 3Unmanned Ground Vehicle (UGV) Market Estimated to Reach $8.26 Billion by 2020 - New Research Report by MarketsandMarkets 4Unmanned Ground Vehicle (UGV) Market Estimated to Reach $8.26 Billion by 2020 - New Research Report by MarketsandMarkets 5
... A decade of helping scientists and clinicians understand life one cell ... ... time, HAYWARD, Calif., Feb. 6 This year ... technologies directly to the lab benches of thousands of,scientists and clinicians ...
... Feb. 5 Anadys Pharmaceuticals,Inc. (Nasdaq: ANDS ) ... Annual,BIO CEO and Investor Conference on Tuesday, February 12, ... is being held at the Waldorf-Astoria,Hotel in New York., ... of Anadys,Pharmaceuticals, Inc., will present an overview of Anadys ...
... ... Expertise, OMAHA, Neb., Feb. ... has appointed David P.,Pauluzzi to its Board of Directors. Mr. Pauluzzi ... equity firm,specializing in the healthcare sector., Prior to his current ...
Cached Biology Technology:Guava Technologies Celebrates Tenth Anniversary 2Anadys Pharmaceuticals to Present at the BIO CEO & Investor Conference 2Transgenomic Appoints David Pauluzzi to Board of Directors 2Transgenomic Appoints David Pauluzzi to Board of Directors 3
(Date:10/18/2014)... with undiagnosed, suspected genetic conditions, a certain type of ... diagnostic yield than traditional molecular diagnostic methods, according to ... is being released to coincide with the American Society ... sequences the protein­coding region of the genome (the complete ... cell or organism), has been rapidly applied in research ...
(Date:10/17/2014)... University of Copenhagen have shown for the first time ... Cystic fibrosis patients, giving them the opportunity to get ... infections. , The study also discovered the bacterial growth ... was halted or slowed down by the immune cells. ... oxygen and helped "suffocate" the bacteria, forcing the bacteria ...
(Date:10/16/2014)... Institute of Marine Science have received a 3-year, ... identify the streams and wetlands most vulnerable to ... local governments and citizens conserve these important ecosystems. ... of tidal-marsh observations first gathered by VIMS scientists ... can today,s researchers accurately map the slow but ...
Breaking Biology News(10 mins):Study examines type of exome sequencing and molecular diagnostic yield 2Study examines type of exome sequencing and molecular diagnostic yield 3Scientists opens black box on bacterial growth in cystic fibrosis lung infection 2EPA grant will help localities conserve headwater wetlands 2EPA grant will help localities conserve headwater wetlands 3
... a long time that only 2% -- 3% of human ... genomes -- often referred to as junk DNA -- consists ... into DNA, and then reinserted into a new spot in ... these retroelements. Retroviruses can insinuate themselves into the host's DNA ...
... presented at the CIC bioGUNE hold at ... DNA chip concerning diagnosis and prognosis of ... normal, steatosis and NASH predisposed subjects. , ... of the liver of unknown etiology, characterized ...
... pioneering research into diseases such as Creutzfeld-Jakob Disease (CJD) and ... to a £300,000 grant from the Medical Research Council. , ... probable variant CJD (vCJD) in the UK. This is the ... with prions that is also responsible for the epidemic of ...
Cached Biology News:Chimp genome reveals a retroviral invasion 2Chimp genome reveals a retroviral invasion 3Owl genomics presents a HEPATOCHIP for diagnosis of non-alcoholic steatohepatitis 2
... APAgene kits are designed to rapidly ... using our patented APA Technology. APAgene provides ... competitive price. All necessary ingredients are provided ... can be used for gap filling, localized ...
... APAgene kits are designed to rapidly ... using our patented APA Technology. ... at an extraordinarily competitive price. All ... kit. The Locator Kit can be ...
A set of five peptides which can be used to calibrate a Matrix-assisted laser desorption/ionization time-of-flight (MALDI-TOF) or Electrospray Ionization (ESI) mass spectrometer....
... System is the only PCR system that ... every time. It provides accuracy, consistency, and ... or the property of the DNA templates. ... Mix, a unique blend of thermostable enzymes ...
Biology Products: