Navigation Links
Researchers create method for more sensitive electrochemical sensors

Graphene and related materials hold promise for the future of electrochemical sensors detectors that measure the concentration of oxygen, toxic gases, and other substances but many applications require greater sensitivity at lower detection ranges than scientists have been able to achieve.

A Northwestern University research team and partners in India have recently developed a new method for amplifying signals in graphene oxide-based electrochemical sensors through a process called "magneto-electrochemical immunoassay." The findings could open up a new class of technologies with applications in medicine, chemistry, and engineering.

Researchers from Northwestern's McCormick School of Engineering and Applied Science, the Northwestern International Institute for Nanotechnology (IIN), the Northwestern University Atomic and Nanoscale Characterization Experimental (NUANCE) Center, and the Institute for Microbial Technology (IMTECH)-India, a national laboratory of India, contributed to the research.

A paper about the work, "Enhancing Electrochemical Detection on Graphene Oxide-CNT Nanostructured Electrodes Using Magneto-Nanobioprobes," was published November 19 in Nature Scientific Reports.

Graphene-based nanocomposite films have recently been used as an effective sensing platform for the development of electrochemical sensors and biosensors because of their unique facile surface modification characteristics and high charge mobility.

The researchers' new concept combines the advantages carbon nanotubes and reduced graphene oxide together with electrochemical bursting of magnetic gold nanoparticles into a large number of metal ions.

High sensitivity was achieved by precisely designing the nanohybrid and correlating the available metal ions with analyte concentration. The researchers used tiny magnetic particles encapsulated in inert coating of silicon dioxide to make core-shell nanostructures with favorable magnetic properties of metallic iron while preventing them from oxidation or significant degradation. They were then coated with gold because of its chemical inertness and biocompatibility.

This novel immune-detection platform shows potential for rapid and sensitive screening of environmental pollutants or toxins in samples. Researchers reported the ultrahigh sensitivity of this method for a new generation of herbicide diuron and its analogues up to sub-picomolar concentration in standard water samples. The process also proved to be efficient and cost-effective: tens of thousands of screen-printed electrodes can be manufactured quite readily with low cost for such hybrid assay.

Contact: Megan Fellman
Northwestern University

Related biology technology :

1. Sustainable Valley Technology Group Provides Technology Innovation Grant To Help Researchers & Start-Ups With Funding, Business Support, Equipment & Facilities
2. Penn researchers show new level of control over liquid crystals
3. Carin Grings remains identified by researchers at Uppsala University
4. MIT researchers discover a new kind of magnetism
5. Elsevier and the Dutch Fulbright Center Start Collaboration to Support Early Career Researchers in the Netherlands
6. Penn researchers make flexible, low-voltage circuits using nanocrystals
7. Researchers improve technology to detect hazardous chemicals
8. Researchers create laser the size of a virus particle
9. Taming mavericks: Stanford researchers use synthetic magnetism to control light
10. Promotion of Young Researchers Supported by Major Donation
11. Penn researchers make first all-optical nanowire switch
Post Your Comments:
(Date:11/24/2015)... -- --> --> ... Market by Product & Services (Primer, Probe, Custom Oligos, ... End-User (Research, Pharmaceutical & Biotech, Diagnostic Labs) - Global ... expected to reach USD 1,918.6 Million by 2020 from ... 10.1% during the forecast period. Browse 183 ...
(Date:11/24/2015)...  Tikcro Technologies Ltd. (OTCQB: TIKRF) today announced that its Annual General ... a.m. Israel time, at the law offices of ... 36 th Floor, Tel Aviv, Israel . ... Izhak Tamir to the Board of Directors; , election ... , approval of an amendment to certain terms of options granted to ...
(Date:11/24/2015)... ... November 24, 2015 , ... Creation Technologies ... being named to Deloitte's 2015 Technology Fast 500 list of the fastest growing ... a FDA-cleared, Class II medical device that speeds up orthodontic tooth movement by ...
(Date:11/24/2015)... MUNICH and NEW YORK , ... irst investment by Bristol-Myers Squibb in a ... Bristol-Myers Squibb Company in which the companies ... products in immuno-oncology and other areas of unmet medical need. ... Squibb in LSP 5, the latest LSP fund. This is ...
Breaking Biology Technology:
(Date:11/9/2015)... , Nov. 9, 2015  Synaptics Inc. (NASDAQ: ... today announced broader entry into the automotive market with ... match the pace of consumer electronics human interface innovation. ... are ideal for the automotive industry and will be ... Europe , Japan ...
(Date:10/29/2015)... Daon, a global leader in mobile biometric ... new version of its IdentityX Platform , IdentityX ... have already installed IdentityX v4.0 and are ... FIDO UAF certified server component as an option ... features. These customers include some of the largest and ...
(Date:10/27/2015)... , Oct. 27, 2015 In the present ... of concern for various industry verticals such as banking, ... to the growing demand for secure & simplified access ... ,sectors, such as hacking of bank accounts, misuse of ... equipment such as PC,s, laptops, and smartphones are expected ...
Breaking Biology News(10 mins):