Navigation Links
Research could lead to new drugs for major diseases
Date:6/11/2012

Researchers at the University of Gothenburg, Sweden, are working to develop substances that can prevent parasites, bacteria and fungi from producing essential proteins, research that could, in the long term, lead to new drugs for several major diseases.

The World Health Organization (WHO) has announced that aminoacyl-tRNA synthetases a type of enzyme are important targets for the development of new drugs for several major diseases such as cancer, various parasitic diseases and bacterial and fungal infections.

These enzymes are involved in the production of proteins (protein synthesis) in all organisms. Their job is to ensure that the right amino acid is linked to the growing protein chain. These enzymes are essential for all living organisms.

Challenging research field

Researchers at the University of Gothenburg are currently undertaking basic research in this challenging field. The aim is to prevent the enzyme from producing proteins in bacteria, parasites or fungi, without stopping it from functioning in the human body.

"We're collaborating with researchers in several countries," says researcher Itedale Namro Redwan. "Our role has been to design and to synthesise substances that can be used for the development of drugs against parasitic diseases."

Looking for an effective substance

The enzymes' job of ensuring that the right amino acid is linked to the growing protein chain works in the same way in all types of cell, be they human or parasitic.

"The real challenge is identifying substances that act on enzymes in the parasite alone, without affecting the human enzymes at the same time," says Itedale Namro Redwan, who is making substances that can prevent bacterial and parasitic enzymes from functioning, but do not affect human enzymes. If this proves possible, it will help in the development of drugs for several major diseases.

"One of our main objectives has been to pr
'/>"/>

Contact: Itedale Namro Redwan
itedale.namro@chem.gu.se
46-031-786-9097
University of Gothenburg
Source:Eurekalert  

Page: 1 2

Related biology technology :

1. Wolters Kluwer Research Now Available via Bloomberg Tradebook
2. ACORN Research, LLC Announces Partnership with AdeptBio, LLC
3. New England Biolabs Introduces Polbase, an Information Repository of Scientific Data for Polymerase Researchers
4. Researching graphene nanoelectronics for a post-silicon world
5. In new quantum-dot LED design, researchers turn troublesome molecules to their advantage
6. BBVA Foundation Unites the Efforts of Massachusetts General Hospital and Barcelonas Vall dHebron Hospital in Biomarker Research for Personalized Cancer Therapies
7. New research points to benefits of innovative cobas® HPV test for primary screening as Englands cervical cancer screening programme includes the test in current HPV "triage" rollout
8. Multidisciplinary team of researchers develop world’s lightest material
9. K computer research results awarded ACM Gordon Bell Prize
10. ResearchMoz: Ophthalmic Devices Market to 2017 - Glaucoma and Cataract Surgery Devices, Minimally Invasive Procedures in Ophthalmic Surgery to Drive the Ophthalmic Surgery Market
11. Researchers shrink tumors and minimize side effects using tumor-homing peptide to deliver treatment
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Research could lead to new drugs for major diseases
(Date:1/15/2014)... 15, 2014 2013 was a banner ... State Technologies®. They saw continued independent research led by ... were awarded a $1 million grant from the Susanne ... and Behavior” a peer reviewed journal, Amy Grant highlighted ...
(Date:1/15/2014)... TaiGen Biotechnology Company, Limited ("TaiGen") today announced that ... leading Russian pharmaceutical company, to develop and commercialize nemonoxacin ... , Turkey and other ... novel antibiotic for the treatment of bacterial infections including ...
(Date:1/14/2014)... Histogen, Inc., a regenerative medicine company developing ... simulated embryonic conditions, today announced that they have entered ... for physician-dispensed aesthetic products containing Histogen’s proprietary multipotent cell ... an amendment to the existing license between Histogen and ...
(Date:1/14/2014)... EquitiesIQ, a leading informational research provider, has ... an emerging biomedical company acquiring, developing, manufacturing, and marketing ... Free report download: http://equitiesiq.com/reports/alliqua/ , In late ... and Board, which launched the company’s new strategy to ...
Breaking Biology Technology:Dynamic Innovative Technology Showcased at Scottsdale Company’s Open House 2Dynamic Innovative Technology Showcased at Scottsdale Company’s Open House 3TaiGen Biotechnology Signed Exclusive License Agreement with R-Pharm for Nemonoxacin (Taigexyn(R)) 2TaiGen Biotechnology Signed Exclusive License Agreement with R-Pharm for Nemonoxacin (Taigexyn(R)) 3TaiGen Biotechnology Signed Exclusive License Agreement with R-Pharm for Nemonoxacin (Taigexyn(R)) 4Histogen and Suneva Medical Expand License for Cell Conditioned Media-based Aesthetic Products Internationally 2Histogen and Suneva Medical Expand License for Cell Conditioned Media-based Aesthetic Products Internationally 3EquitiesIQ Initiates Coverage of Alliqua, Inc. 2EquitiesIQ Initiates Coverage of Alliqua, Inc. 3
... Widespread use of nanoscale silver will challenge regulatory ... possibility of significant environmental risk, highlighting the need ... according to a new report released today by ... But existing information about the impact of silver ...
... Inc., (TSX:,ARI), a biotechnology company discovering and developing ... RiskMetrics ISS Canada,Canada,s leading independent proxy firm, has ... and are recommending that ARIUS shareholders,and warrant holders ... Roche,will acquire all of ARIUS, outstanding shares and ...
... NewsRx, a 25-year-old publisher and,international news organization headquartered ... and psychiatry/psychology., These new titles will cover ... news and developments in pediatric,and psychiatric medicine. The ... print or online at http://www.NewsRx.com . ...
Cached Biology Technology:Nanoscale silver: No silver lining? 2Nanoscale silver: No silver lining? 3Arius announces leading independent proxy firm, RiskMetrics ISS Canada, recommends shareholders vote for the arrangement involving its acquisition by Roche 2Arius announces leading independent proxy firm, RiskMetrics ISS Canada, recommends shareholders vote for the arrangement involving its acquisition by Roche 3NewsRx Adds Pediatrics and Psychiatry Titles 2
(Date:4/23/2014)... and German . ... the difference between sexes depends on one single element of the ... the two sexual chromosomes are X and Y, whereas women have ... the morphological and physiological differences between males and females. , But ... ago, the X and Y were identical, until the Y started ...
(Date:4/23/2014)... ripping open a dinner roll, a fuel cell catalyst ... hydrogen molecule. Now researchers have captured a view of ... its hydrogen feast. The view confirms previous hypotheses and ... better for alternative energy uses. , This study is ... hydrogen halves end up in the structure of a ...
(Date:4/23/2014)... is available in French and Spanish ... 23 April 2014Today, the CEC released its Conservation Assessment ... Approach to Conservation, which identifies 29 priority conservation areas ... includes 11 different protected areas in the states of ... diverse arid and semi-arid habitats inhabited by rare and ...
Breaking Biology News(10 mins):Male or female? 2Male or female? 3Halving hydrogen 2Halving hydrogen 3Halving hydrogen 4Conservation priorities released for several protected areas along US-Mexico border 2Conservation priorities released for several protected areas along US-Mexico border 3
... in French . , A study led ... between individuals at the DNA level can lead to ... in turn, are responsible for the vast array of ... of the Genome Regulators in Disease (GRID) Project funded ...
... the elixir of all life, water is a very unusual ... water apart from other solids and liquids commonly found in ... freezes -- an effect known to anyone whose plumbing has ... long list of special characteristics. (Most liquids contract when they ...
... CREEK, CA--A preliminary assembly and annotation of the soybean ... U.S. Department of Energy Joint Genome Institute (DOE JGI), ... The announcement was made by Eddy Rubin, DOE ... the Plant and Animal Genome XVI Conference in San ...
Cached Biology News:Tiny genetic differences have huge consequences: McGill researchers 2Weird water: Discovery challenges long-held beliefs about water's special properties 2Weird water: Discovery challenges long-held beliefs about water's special properties 3DOE JGI releases soybean genome assembly to enable worldwide bioenergy research efforts 2DOE JGI releases soybean genome assembly to enable worldwide bioenergy research efforts 3
... 2000 instrument can be used as a ... Data Manager Software provides the means to ... the instrument. These data can then be ... such as Microsoft Excel or Lotus 123, ...
... allows for quick and reproducible immunoprecipitation (IP) by ... is more reproducible than regular IPs, which are ... agarose without disrupting the agarose bed. The binding ... is reversible, and elution of the immune complex ...
... description: self locking design in ice/water ... new product number, created to easily ... no availability yet, please order under ... contact customer service for assistance. ID ...
Kit containing MACS equipment and reagents for immunopurification of proteins....
Biology Products: