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Date:6/3/2010

Vaccines 83

Live attenuated influenza vaccine vs. inactivated vaccine 84

Vaccines for H1N1 influenza 84

Vaccines in development 85

Cell culture-derived influenza vaccines 85

DNA vaccines for avian influenza 86

Epitope-based vaccines for influenza 86

Gene-based vaccines for influenza 87

MAbs for passive immunization against avian influenza 87

M2e-based human influenza A vaccine. 87

MF-59 as adjuvant for influenza vaccine 88

Pre-pandemic split antigen H5N1 vaccine 88

Recombinant hemagglutinin influenza vaccine 89

Synthetic avian influenza vaccine 89

Virus-like particles as influenza vaccines 90

Current status of influenza vaccines and limitations 91

Current recommendations for influenza vaccination 91

Limitations of current influenza vaccines 91

Needs of influenza vaccines 92

Problems with demand and supply of influenza vaccines 93

Problems with access to virus samples 93

FluVac project for development of pandemic influenza vaccine 94

Influenza vaccines for multiple strains of the disease 94

Current status of vaccine preparedness against seasonal influenza 94

Current status of vaccine preparedness against H5N1 95

RNAi-based approaches 95


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